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NTRA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
225.700
Open
214.970
VWAP
220.16
Vol
2.69M
Mkt Cap
31.99B
Low
211.396
Amount
592.51M
EV/EBITDA(TTM)
--
Total Shares
143.22M
EV
30.98B
EV/OCF(TTM)
146.82
P/S(TTM)
12.36
Natera, Inc. provides cell-free DNA (cfDNA) and genetic testing, dedicated to oncology, women’s health, and organ health. The Company's cfDNA technology platform combines novel molecular biology techniques with bioinformatics software and artificial intelligence. It has leveraged its platform to develop non-invasive prenatal test on the market (Panorama), the first tumor-specific assay for truly individualized cancer care (Signatera), best-in-class rejection assessment for kidney transplantation (Prospera) and others. In the women’s health space, it develops and commercializes non- or minimally- invasive tests to evaluate risk for, and thereby enable early detection of, a range of genetic conditions, such as Down syndrome. In oncology, it is focused on detecting molecular residual disease and recurrence monitoring in solid tumors, among others. In organ health, it offers tests to assess kidney, heart, and lung transplant rejection as well as genetic testing for chronic kidney disease.
Show More

Events Timeline

(ET)
2026-05-29
06:20:00
Natera Collaborates with Diakonos on New Immunotherapy Development
select
2026-05-28 (ET)
2026-05-28
06:10:00
Natera Begins Enrollment of First Patients in SIgnatera-Guided Study
select
2026-05-21 (ET)
2026-05-21
07:20:00
Natera Expands Operations in North Austin, World's Largest Sequencing Capacity
select
2026-05-20 (ET)
2026-05-20
07:10:00
Natera's Expand Clinical Trial Enrolls Over 2,000 Patients
select
2026-05-15 (ET)
2026-05-15
12:50:00
Genentech Receives FDA Approval for Tecentriq in Bladder Cancer
select
2026-05-15
12:50:00
Natera's Signatera CDx Approved by FDA for MIBC
select

News

Newsfilter
7.5
05-29Newsfilter
Natera Partners with Diakonos to Evaluate New Therapy
  • Collaboration Background: Natera has partnered with Diakonos Oncology Corp. to utilize Signatera™ for assessing molecular responses in patients with refractory melanoma enrolled in the DOC-RM clinical trial, marking a significant advancement in precision medicine for cancer treatment.
  • Clinical Trial Progress: The DOC-RM trial, which began enrollment in May, evaluates the FDA Fast Track-designated DOC1021 therapy, aiming to provide new treatment options for patients with unresectable or metastatic cutaneous melanoma, indicating potential positive impacts on patient outcomes.
  • Technical Advantage: By analyzing circulating tumor DNA (ctDNA) at multiple timepoints, Natera's Signatera test can offer earlier insights into molecular responses compared to traditional imaging, enabling physicians to better understand treatment dynamics and optimize therapeutic strategies.
  • Market Demand: Patients with refractory melanoma face significant unmet medical needs, and the collaboration between Natera and Diakonos not only aims to address this gap but also has the potential to drive the development of new therapies, enhancing patient survival rates and quality of life.
NASDAQ.COM
8.5
05-28NASDAQ.COM
Natera Initiates SIGNAL-ER 101 Study for Early-Stage Breast Cancer
  • Study Launch: Natera Inc. has enrolled its first patient in the SIGNAL-ER 101 study, aimed at facilitating diagnosis and treatment for early-stage breast cancer through the Signatera MRD test, marking a significant advancement in precision medicine.
  • Patient Recruitment Plan: The study plans to enroll 725 intermediate-risk HR+/HER- early-stage breast cancer patients, allowing those diagnosed as MRD negative via the Signatera test to receive endocrine therapy alone, thus avoiding unnecessary CDK4/6 inhibitor treatment.
  • Efficacy Improvement: Endocrine therapy shows a 95% recurrence-free success rate in MRD negative patients, highlighting the importance of the Signatera test in optimizing treatment regimens and potentially improving patient outcomes significantly.
  • Market Reaction: Natera's stock is currently trading at $205.52, up 1.19%, reflecting positive market sentiment regarding the progress of its new study, which may drive further investment and development in the precision medicine sector.
Newsfilter
2.0
05-28Newsfilter
Natera Launches SIGNAL-ER 101 Trial for Breast Cancer Treatment De-escalation
  • SIGNAL-ER 101 Trial Launch: Natera has initiated the SIGNAL-ER 101 trial to evaluate the clinical utility of Signatera MRD-guided de-escalation strategies in early-stage HR+/HER2- breast cancer, aiming to enroll 725 patients across 50 sites in the U.S.
  • Standard of Care Transformation: The current standard recommends 2-3 years of CDK4/6 inhibitors for intermediate-risk HR+/HER2- breast cancer patients, yet only about 3% benefit, with over 60% experiencing serious adverse events, indicating a critical need to reassess treatment necessity and efficacy.
  • Potential of MRD-Negative Patients: Data shows that MRD-negative patients tested with Signatera have over 95% distant recurrence-free interval at 5 years, suggesting they can safely defer CDK4/6 inhibition, thereby reducing unnecessary treatments and associated side effects.
  • Optimizing Treatment Strategies: The implementation of SIGNAL-ER 101 not only helps mitigate overtreatment in breast cancer patients but also provides crucial evidence for Natera's innovations in cancer treatment, supporting MRD-based personalized treatment optimization and enhancing patient quality of life.
Newsfilter
3.5
05-26Newsfilter
Natera Enhances Panorama NIPT with Low Fetal Fraction Technology
  • Technological Innovation: Natera's Panorama non-invasive prenatal test (NIPT) has successfully reduced the no-call rate to 0.5% for low fetal fraction samples through SNP-informed deep sequencing technology, significantly enhancing the accuracy and reliability of testing, thereby enabling more patients to receive actionable results.
  • Clinical Validation: In a prospective clinical validation study involving 3,323 high- and low-risk pregnant patients, Panorama demonstrated 100% sensitivity for trisomy 21 and 93.3% sensitivity for trisomy 18 in low fetal fraction samples, indicating a substantial improvement in its competitive edge in this critical area.
  • Market Demand Fulfillment: Low fetal fraction has remained a significant challenge in non-invasive prenatal screening, and Natera's application of this new technology not only addresses this issue but also fills the gap in the market regarding performance data for low fetal fraction testing, thereby enhancing its market competitiveness.
  • Strategic Implications: This technological upgrade not only improves Panorama's clinical performance but also simplifies processes for healthcare providers by delivering more reliable testing results, positioning the company favorably in the rapidly evolving prenatal testing market.
seekingalpha
9.0
05-15seekingalpha
FDA Approves Tecentriq for Bladder Cancer Treatment
  • New Indication Approved: The FDA has approved Roche-owned Genentech's Tecentriq (atezolizumab) as an adjuvant treatment for adult patients with muscle-invasive bladder cancer (MIBC), specifically targeting those with circulating tumor DNA molecular residual disease after cystectomy, marking a significant expansion in cancer treatment applications.
  • Companion Diagnostic Approved: The FDA also approved Natera's Signatera CDx as a companion diagnostic for this indication, aimed at identifying ctDNA MRD-positive patients who are likely to benefit from Tecentriq therapy, thereby enhancing treatment precision and effectiveness.
  • Increased Indications: Tecentriq now boasts 11 approved indications, demonstrating its broad applicability in oncology and strengthening Roche's competitive position in the oncology market while providing patients with more treatment options.
  • Positive Market Outlook: With the expansion of Tecentriq's indications, Roche's market outlook in oncology appears optimistic, expected to drive future sales growth and solidify its leadership position in the biopharmaceutical industry.
Newsfilter
9.0
05-15Newsfilter
Natera Receives FDA Approval for Personalized MRD Testing
  • FDA Approval Milestone: Natera's Signatera CDx has received FDA approval as the first personalized molecular residual disease (MRD) test for MIBC patients, marking a new standard in precision cancer treatment that is expected to significantly improve outcomes for MRD-positive patients.
  • Clinical Trial Support: The IMvigor011 trial demonstrated that MRD-positive patients treated with immunotherapy achieved significant improvements in disease-free survival (DFS) and overall survival (OS), while MRD-negative patients had a 97% two-year OS without any adjuvant therapy, providing crucial evidence for clinical decision-making.
  • Significant Market Potential: With approximately 30,000 new MIBC diagnoses annually in the U.S. and 150,000 globally, the application of Signatera will assist physicians in accurately identifying recurrence risks, optimizing treatment plans, and reducing unnecessary therapies, thereby enhancing patient quality of life.
  • Signal of Industry Transformation: This approval not only validates Natera's decade-long vision but also propels the advancement of precision oncology, likely leading to the application of MRD testing across more cancer types, further improving patient treatment outcomes and survival rates.
Wall Street analysts forecast NTRA stock price to rise
13 Analyst Rating
Wall Street analysts forecast NTRA stock price to rise
12 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
205.00
Averages
262.92
High
300.00
Current: 0.000
sliders
Low
205.00
Averages
262.92
High
300.00
Piper Sandler
Overweight
maintain
$240 -> $249
AI Analysis
2026-05-12
Reason
Piper Sandler
Price Target
$240 -> $249
AI Analysis
2026-05-12
maintain
Overweight
Reason
Piper Sandler raised the firm's price target on Natera to $249 from $240 and keeps an Overweight rating on the shares. The firm notes the company has $1B in cash and equivalents, $210M in debt and 141.5M shares outstanding.
Baird
NULL
to
Outperform
maintain
$257 -> $265
2026-05-08
Reason
Baird
Price Target
$257 -> $265
2026-05-08
maintain
NULL
to
Outperform
Reason
Baird raised the firm's price target on Natera to $265 from $257 and keeps an Outperform rating on the shares. The firm updated its model following Q1 results and strong start to 2026.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for NTRA
Unlock Now

Valuation Metrics

The current forward P/E ratio for Natera Inc (NTRA.O) is 0.00, compared to its 5-year average forward P/E of -40.87. For a more detailed relative valuation and DCF analysis to assess Natera Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-40.87
Current PE
0.00
Overvalued PE
-4.65
Undervalued PE
-77.08

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-53.69
Current EV/EBITDA
-80.29
Overvalued EV/EBITDA
14.00
Undervalued EV/EBITDA
-121.39

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.47
Current PS
8.88
Overvalued PS
11.98
Undervalued PS
4.96

Financials

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Whales Holding NTRA

S
Summit Partners Public Asset Management, LLC
Holding
NTRA
+37.54%
3M Return
R
Rokos Capital Management LLP
Holding
NTRA
+28.31%
3M Return
F
Fred Alger Management, LLC
Holding
NTRA
+25.20%
3M Return
B
Bluebox Asset Management Uk Ltd.
Holding
NTRA
+24.26%
3M Return
Z
Zevenbergen Capital Investments LLC
Holding
NTRA
+24.04%
3M Return
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Paradigm Capital Management, Inc.
Holding
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+21.80%
3M Return

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Frequently Asked Questions

What is Natera Inc (NTRA) stock price today?

The current price of NTRA is 223.37 USD — it has increased 4.41

What is Natera Inc (NTRA)'s business?

Natera, Inc. provides cell-free DNA (cfDNA) and genetic testing, dedicated to oncology, women’s health, and organ health. The Company's cfDNA technology platform combines novel molecular biology techniques with bioinformatics software and artificial intelligence. It has leveraged its platform to develop non-invasive prenatal test on the market (Panorama), the first tumor-specific assay for truly individualized cancer care (Signatera), best-in-class rejection assessment for kidney transplantation (Prospera) and others. In the women’s health space, it develops and commercializes non- or minimally- invasive tests to evaluate risk for, and thereby enable early detection of, a range of genetic conditions, such as Down syndrome. In oncology, it is focused on detecting molecular residual disease and recurrence monitoring in solid tumors, among others. In organ health, it offers tests to assess kidney, heart, and lung transplant rejection as well as genetic testing for chronic kidney disease.

What is the price predicton of NTRA Stock?

Wall Street analysts forecast NTRA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NTRA is262.92 USD with a low forecast of 205.00 USD and a high forecast of 300.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Natera Inc (NTRA)'s revenue for the last quarter?

Natera Inc revenue for the last quarter amounts to 696.64M USD, increased 38.82

What is Natera Inc (NTRA)'s earnings per share (EPS) for the last quarter?

Natera Inc. EPS for the last quarter amounts to -0.60 USD, increased 20.00

How many employees does Natera Inc (NTRA). have?

Natera Inc (NTRA) has 6135 emplpoyees as of June 01 2026.

What is Natera Inc (NTRA) market cap?

Today NTRA has the market capitalization of 31.99B USD.