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ALNY Overview

-
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
282.980
Open
280.110
VWAP
278.06
Vol
2.21M
Mkt Cap
37.13B
Low
273.110
Amount
613.04M
EV/EBITDA(TTM)
45.64
Total Shares
133.51M
EV
36.83B
EV/OCF(TTM)
51.66
P/S(TTM)
8.80
Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) in adults ; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Zilebesiran, Elebsiran, Mivelsiran, ALN-6400, and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.
Show More

Events Timeline

(ET)
2026-06-03
16:50:00
Alnylam and Inceptive Sign Up to $2B Strategic Collaboration Agreement
select
2026-05-12 (ET)
2026-05-12
05:50:00
Alnylam Releases New Analyses Supporting Vutrisiran for Cardiac Amyloidosis Treatment
select
2026-05-07 (ET)
2026-05-07
09:40:00
MBX Biosciences Appoints Mark Soued as Chief Commercial Officer
select
2026-04-30 (ET)
2026-04-30
08:10:00
Alnylam Reports Q1 Revenue of $1.167B
select

News

Newsfilter
8.5
06-12Newsfilter
Alnylam to Host 10th RNAi Roundtable Series
  • RNAi Roundtable Series: Alnylam Pharmaceuticals announced its plan to host the 10th series of 'RNAi Roundtable' webinars in the coming months, featuring presentations from scientists and medical experts discussing recent advancements in the company's pipeline programs to address unmet clinical needs.
  • Live Webcast Arrangement: Each event will be webcast live on the company's investor website, with replays available approximately three hours after each session, ensuring timely access to critical information for investors.
  • 2030 Strategic Goals: Alnylam aims to increase its clinical programs from over 25 to more than 40 by 2030, demonstrating its commitment to sustainable innovation and market expansion in the RNAi therapeutics sector.
  • Increased R&D Investment: The company is significantly ramping up its R&D investments to extend the application of RNAi technology, aiming to deliver multiple new transformative medicines for patients with serious diseases, thereby reinforcing its market leadership position.
NASDAQ.COM
4.5
06-04NASDAQ.COM
US Stocks Close Mixed: Dow Hits All-Time High
  • Dow Hits Record High: The Dow Jones Industrial Average rose 1.73% to reach an all-time high, reflecting strong rebounds in bank and managed healthcare stocks, despite a 0.53% decline in the Nasdaq 100 due to weakness in technology stocks.
  • Crude Oil Prices Decline: WTI crude oil prices fell over 3%, lowering inflation expectations and pushing the 10-year T-note yield down 2 basis points to 4.47%, providing support for both stock and bond markets, indicating a complex market reaction to economic outlooks.
  • Jobless Claims Rise: Initial jobless claims in the US increased by 13,000 to 225,000, marking a 3.75-month high, suggesting a weaker labor market, although unit labor costs were unexpectedly revised down to 1.8%, easing concerns over wage pressures.
  • Earnings Season Summary: As of Thursday, 83% of the 494 S&P 500 companies reported earnings that beat estimates, with Q1 earnings projected to rise 12% year-over-year, but excluding the tech sector, growth is only about 3%, the lowest in two years, reflecting divergence across industries.
NASDAQ.COM
4.5
06-04NASDAQ.COM
Dow Jones Hits All-Time High Amid Mixed Market Performance
  • Dow Jones High: The Dow Jones Industrial Average surged 1.49% to reach a new all-time high, demonstrating market resilience driven by strong performance in managed healthcare stocks, despite overall market pressures.
  • Tech Sector Decline: Broadcom's stock plummeted over 14% due to disappointing AI revenue forecasts, leading to a broader decline in chipmakers, while CrowdStrike fell more than 8% despite beating Q1 earnings expectations, reflecting market caution towards tech stocks.
  • Mixed Economic Data: Initial jobless claims rose to 225,000, a 3.75-month high, indicating a weaker labor market, while Q1 nonfarm productivity was revised down to 0.3%, below expectations, potentially impacting future economic growth outlooks.
  • Oil Price Impact: WTI crude oil prices fell over 3% amid a ceasefire agreement between Israel and Lebanon, which lowered inflation expectations and provided support for both stock and bond markets, improving investor sentiment.
CNBC
2.0
06-04CNBC
Alnylam Partners with Inceptive in AI Collaboration
  • Strategic Collaboration: Alnylam Pharmaceuticals has entered into a strategic AI partnership with Inceptive Nucleics valued at up to $2 billion, aiming to leverage Inceptive's generative AI models to accelerate the discovery of RNA interference therapeutics, thereby enhancing its competitive edge in the biopharmaceutical sector.
  • Market Rebound: Blackstone's shares rose 8% despite the firm limiting withdrawals from its Private Credit fund, indicating investor confidence as the stock is poised to end a three-day losing streak, reflecting a positive sentiment towards asset management firms.
  • Stock Volatility: Broadcom's shares tumbled nearly 15% after reporting second-quarter revenue of $22.19 billion, falling short of the $22.27 billion expected by analysts, although CEO Hock Tan reiterated the company's fiscal year 2027 revenue guidance for AI chips to exceed $100 billion, raising concerns about future growth prospects.
  • Healthcare Outlook: UnitedHealth's stock climbed 5% following an upgrade from Bank of America from neutral to buy, citing improving medical cost trends and supportive near-term data points that are expected to favorably impact second-quarter earnings, reflecting optimism in the health insurance sector.
NASDAQ.COM
4.5
06-04NASDAQ.COM
Mixed US Stock Market with Tech Stocks Under Pressure
  • Tech Stock Decline: Broadcom (AVGO) shares plummeted over 15% after its AI revenue forecast fell short, marking it as the largest decliner in the Nasdaq 100, which reflects growing concerns about the tech sector and may dampen investor confidence.
  • Weak Employment Data: Initial jobless claims in the US rose by 13,000 to 225,000, reaching a 3.75-month high, indicating a weakening labor market that could lead to downward revisions in growth expectations.
  • Healthcare Stocks Strong: UnitedHealth Group (UNH) surged over 6%, leading gains in the S&P 500, after Bank of America upgraded its rating from neutral to buy with a price target of $450, showcasing resilience in the healthcare sector.
  • International Market Volatility: European markets showed mixed results, with Eurozone April retail sales falling 0.4% month-over-month, worse than the expected 0.3%, indicating weak consumer spending that could pressure future economic growth.
NASDAQ.COM
7.5
06-04NASDAQ.COM
Alnylam Partners with Inceptive for $2 Billion AI-Driven Collaboration
  • Strategic Partnership: Alnylam Pharmaceuticals has entered into a partnership with AI-driven biotechnology company Inceptive Nucleics in a deal valued at up to approximately $2 billion, aiming to combine expertise in RNA interference therapeutics with AI capabilities to accelerate the design and discovery of nucleic acid-based medicines.
  • Technology Integration: By integrating Inceptive's generative AI models into its R&D platform, Alnylam plans to expedite RNAi drug discovery and advance its pipeline expansion goals outlined in the Alnylam 2030 strategy, thereby enhancing its competitive position in the market.
  • Financial Terms: Under the agreement, Inceptive will receive a $30 million upfront payment and will be eligible for additional payments tied to the achievement of preclinical, regulatory, and commercial sales milestones, providing substantial financial support for Inceptive's technological advancements.
  • Stock Market Reaction: Alnylam shares closed at $292.58 on Wednesday and rose more than 2% in after-hours trading, indicating a positive market response to the partnership, which may bolster investor confidence in the company's future growth potential.
Wall Street analysts forecast ALNY stock price to rise
17 Analyst Rating
Wall Street analysts forecast ALNY stock price to rise
14 Buy
3 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
351.00
Averages
479.53
High
580.00
Current: 0.000
sliders
Low
351.00
Averages
479.53
High
580.00
Citi
NULL
to
Buy
initiated
$380
AI Analysis
2026-05-18
Reason
Citi
Price Target
$380
AI Analysis
2026-05-18
initiated
NULL
to
Buy
Reason
Citi initiated coverage of Alnylam with a Buy rating and $380 price target. The expanded launch of Amvuttra for ATTR-CM has \"no doubt been impressive,\" says the analyst, who views 28% year-to-date pullback as \"an attractive long-term entry point.\" Pressure has been led by competitor concerns, but the firm sees \"more tailwinds than headwinds for Amvuttra,\" the analyst added.
Morgan Stanley
Equal Weight
maintain
$360 -> $370
2026-05-01
Reason
Morgan Stanley
Price Target
$360 -> $370
2026-05-01
maintain
Equal Weight
Reason
Morgan Stanley raised the firm's price target on Alnylam to $370 from $360 and keeps an Equal Weight rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ALNY
Unlock Now

Valuation Metrics

The current forward P/E ratio for Alnylam Pharmaceuticals Inc (ALNY.O) is 30.30, compared to its 5-year average forward P/E of -37.48. For a more detailed relative valuation and DCF analysis to assess Alnylam Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-37.48
Current PE
30.30
Overvalued PE
37.79
Undervalued PE
-112.76

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-7407.76
Current EV/EBITDA
21.43
Overvalued EV/EBITDA
51058.09
Undervalued EV/EBITDA
-65873.61

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
14.04
Current PS
5.15
Overvalued PS
18.50
Undervalued PS
9.57

Financials

AI Analysis
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Whales Holding ALNY

B
Bluebox Asset Management Uk Ltd.
Holding
ALNY
+107.56%
3M Return
N
Nomura Asset Management Taiwan Ltd.
Holding
ALNY
+31.50%
3M Return
D
Deerfield Management Company, L.P.
Holding
ALNY
+20.88%
3M Return
C
Capital Research
Holding
ALNY
+19.44%
3M Return
R
Rock Springs Capital Management LP
Holding
ALNY
+18.31%
3M Return
T
Two Sigma Investments, LP
Holding
ALNY
+17.99%
3M Return

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Frequently Asked Questions

What is Alnylam Pharmaceuticals Inc (ALNY) stock price today?

The current price of ALNY is 278.09 USD — it has decreased -1.64

What is Alnylam Pharmaceuticals Inc (ALNY)'s business?

Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) in adults ; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Zilebesiran, Elebsiran, Mivelsiran, ALN-6400, and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.

What is the price predicton of ALNY Stock?

Wall Street analysts forecast ALNY stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALNY is479.53 USD with a low forecast of 351.00 USD and a high forecast of 580.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Alnylam Pharmaceuticals Inc (ALNY)'s revenue for the last quarter?

Alnylam Pharmaceuticals Inc revenue for the last quarter amounts to 1.17B USD, increased 96.43

What is Alnylam Pharmaceuticals Inc (ALNY)'s earnings per share (EPS) for the last quarter?

Alnylam Pharmaceuticals Inc. EPS for the last quarter amounts to 1.51 USD, decreased -1178.57

How many employees does Alnylam Pharmaceuticals Inc (ALNY). have?

Alnylam Pharmaceuticals Inc (ALNY) has 2500 emplpoyees as of June 20 2026.

What is Alnylam Pharmaceuticals Inc (ALNY) market cap?

Today ALNY has the market capitalization of 37.13B USD.