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ENGN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
8.370
Open
8.000
VWAP
7.44
Vol
1.42M
Mkt Cap
581.47M
Low
6.900
Amount
10.55M
EV/EBITDA(TTM)
--
Total Shares
66.99M
EV
411.06M
EV/OCF(TTM)
--
P/S(TTM)
--
enGene Holdings Inc. is a clinical-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II study, which includes a cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (Cis). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. The Company is developing non-viral genetic medicines based on its DDX gene delivery platform, which allows localized delivery of multiple gene cargos directly to mucosal tissues and other organs.
Show More

Events Timeline

(ET)
2026-03-09
07:10:00
enGene Cash and Securities Reach $312.5M, Expected to Fund Operations Until H2 2028
select
2026-02-19 (ET)
2026-02-19
16:40:00
enGene Files $400M Mixed Securities Shelf
select
2025-12-22 (ET)
2025-12-22
16:10:00
LEGEND Raises $140.1M, Cash Reserves Reach $342.4M
select
2025-12-02 (ET)
2025-12-02
07:50:00
enGene's Detalimogene Voraplasmid Selected for FDA Pilot Program
select
2025-11-13 (ET)
2025-11-13
06:14:19
enGene Prices 12.559 Million Share Spot Secondary Offering at $8.50
select
2025-11-12 (ET)
2025-11-12
16:06:54
enGene Announces Offering of Common Shares, Amount Not Disclosed
select

News

seekingalpha
9.5
18:12 PMseekingalpha
enGene Holdings Q1 Financial Highlights
  • Earnings Performance: enGene Holdings reported a Q1 GAAP EPS of $0.44, indicating stable profitability despite competitive market pressures.
  • Cash Position: As of January 31, 2026, the company held $312.5 million in cash, cash equivalents, and marketable securities, providing ample funding for future investments and operations.
  • Operating Expense Increase: Operating expenses for Q1 2026 totaled $31.2 million, a 17.3% increase from $26.6 million in 2025, reflecting ongoing investments in R&D and market expansion.
  • Positive Market Reaction: enGene Holdings saw a 14% surge in stock price on Friday, indicating investor optimism regarding the company's future prospects, particularly with major catalysts on the horizon.
Yahoo Finance
1.0
02-20Yahoo Finance
enGene Holdings to Participate in Multiple Investor Conferences
  • Investor Conference Schedule: enGene Holdings will present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference on February 26, 2026, showcasing its advancements in gene therapy, which is expected to attract investor interest and enhance the company's visibility.
  • Timing and Format: The company will also participate in fireside chats at the Leerink Partners Global Healthcare Conference on March 9 and the Barclays Global Healthcare Conference on March 10, scheduled for 8:00 AM and 9:00 AM respectively, aiming to engage in deeper discussions with investors to bolster market confidence.
  • Product Development Progress: enGene's lead program, detalimogene voraplasmid, is currently in the ongoing LEGEND Phase 2 trial focusing on treating patients with Non-Muscle Invasive Bladder Cancer, demonstrating the company's potential in addressing high clinical need diseases, which may lay the groundwork for future market performance.
  • Platform Technology Advantage: The product utilizes enGene's proprietary DDX platform, which enables effective penetration of mucosal tissues and delivery of various therapeutic payloads, enhancing the company's competitiveness in the gene therapy sector and is expected to drive future product line expansion.
Yahoo Finance
8.5
02-20Yahoo Finance
EnGene Files Shelf Registration for Up to $40 Million
  • Funding Initiative: EnGene filed a shelf registration statement late Thursday for a potential sale of up to $40 million, aiming to provide flexibility for future capital needs and enhance the company's financial stability.
  • Market Reaction: This move may attract investor attention, particularly in the biotech sector, where enhanced funding capabilities are often viewed as a positive signal for a company's expansion in R&D and marketing.
  • Strategic Implications: By establishing a funding channel, EnGene can more effectively respond to market changes and industry competition, thereby improving its competitiveness in the biopharmaceutical market.
  • Future Outlook: The implementation of this funding plan will provide EnGene with the necessary financial support to drive product development and market expansion, further solidifying its position in the industry.
seekingalpha
8.5
01-23seekingalpha
enGene Holdings Inc. (ENGN) Expands $125M Debt Facility, Stock Rises 14%
  • Stock Surge: enGene Holdings Inc. saw a 14% increase in stock price on Friday, closing at $12.12, which is a $1.48 gain from the previous session, reflecting strong market confidence in its financial health.
  • Debt Facility Expansion: The company announced an expanded $125 million debt facility with Hercules Capital, Inc., which includes $100 million in new loan proceeds and $25 million to refinance existing debt, enhancing its financial flexibility.
  • Strong Market Performance: ENGN's stock has risen in eight of the past nine trading sessions, climbing approximately 47% since January 6, and reached a new 52-week high of $12.25 on Friday, indicating investor optimism about its future potential.
  • Clear Future Plans: CEO Ron Cooper stated that the additional capital will support the company's plans for a BLA filing in the second half of this year and a potential commercial launch in 2027, showcasing its strategic positioning in the gene therapy sector.
Businesswire
8.5
01-20Businesswire
enGene Holdings Secures $125 Million Loan Agreement with Hercules Capital
  • Financing Enhancement: enGene has entered into an amended loan agreement with Hercules Capital for up to $125 million in non-dilutive capital, strengthening the company's financial flexibility in preparation for its planned Biologics License Application (BLA) to the FDA in the second half of 2026.
  • Clinical Trial Support: The loan agreement includes an initial $25 million for refinancing existing debt, with an additional $75 million available based on clinical and regulatory milestones, ensuring continued R&D in high-risk non-muscle invasive bladder cancer (NMIBC) treatment.
  • Significant Market Potential: Approximately 75-80% of new bladder cancer diagnoses are NMIBC, with BCG-unresponsive patients facing a 50-70% recurrence rate, making enGene's detalimogene voraplasmid a promising innovative bladder-sparing treatment option to meet urgent market needs.
  • Deepening Strategic Partnership: Hercules Capital's support underscores its commitment as a long-term capital partner and highlights the importance of financing innovative life sciences companies, aiding enGene in the potential commercial launch of detalimogene in 2027.
Newsfilter
9.0
2025-12-02Newsfilter
enGene Selected for FDA CDRP Program to Accelerate Drug Development
  • FDA Program Participation: enGene's detalimogene voraplasmid has been selected for the FDA's Chemistry, Manufacturing, and Controls Development and Readiness Pilot (CDRP) program, which aims to expedite clinical development timelines and provide patients with earlier access to therapies.
  • Manufacturing Capacity Enhancement: Detalimogene has already been scaled to commercial manufacturing levels, and participation in the CDRP is expected to facilitate additional FDA interactions to ensure CMC readiness for a Biologics License Application (BLA) submission in the second half of 2026.
  • Clinical Trial Progress: In the pivotal cohort of the LEGEND trial, detalimogene demonstrated a 62% six-month complete response rate among 125 high-risk NMIBC patients, indicating its potential effectiveness for BCG-unresponsive patients.
  • Strategic Implications: This FDA recognition not only bolsters enGene's confidence in detalimogene's potential but also underscores the company's commitment to strong manufacturing practices, aiming to address the urgent medical needs of high-risk NMIBC patients.
Wall Street analysts forecast ENGN stock price to rise
8 Analyst Rating
Wall Street analysts forecast ENGN stock price to rise
7 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
10.00
Averages
23.88
High
33.00
Current: 0.000
sliders
Low
10.00
Averages
23.88
High
33.00
Jefferies
initiated
$28
AI Analysis
2026-01-30
Reason
Jefferies
Price Target
$28
AI Analysis
2026-01-30
initiated
Reason
Jefferies initiated coverage of enGene with a Buy rating and $28 price target. The company is running a pivotal high-risk non-muscle invasive bladder cancer study with a key update in the second half of 2026, the analyst tells investors in a research note. The firm says enGene's interim data are competitive versus cretostimogene with a "clear differentiator" being the company's practice-friendly profile. enGene's detalimogene is "positioned to stand out," contends Jefferies.
UBS
Neutral
maintain
$4 -> $10
2025-11-12
Reason
UBS
Price Target
$4 -> $10
2025-11-12
maintain
Neutral
Reason
UBS raised the firm's price target on enGene (ENGN) to $10 from $4 and keeps a Neutral rating on the shares. EnGene reported updated Phase 2 LEGEND trial data for detalimogene in high-risk BCG-unresponsive non-muscle invasive bladder cancer, showing a 63% anytime complete response rate and 62% six-month CR under the amended protocol, an improvement from prior results but below competitors CG Oncology (CGON) and Johnson & Johnson (JNJ), the analyst tells investors in a research note. While the results confirm deta's activity, limited near-term catalysts and a later market entry contribute to a Neutral outlook.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ENGN
Unlock Now

Valuation Metrics

The current forward P/E ratio for enGene Holdings Inc (ENGN.O) is -3.71, compared to its 5-year average forward P/E of -3.05. For a more detailed relative valuation and DCF analysis to assess enGene Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.05
Current PE
-3.71
Overvalued PE
-0.13
Undervalued PE
-5.97

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.08
Current EV/EBITDA
-2.81
Overvalued EV/EBITDA
1.25
Undervalued EV/EBITDA
-5.40

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Annual
Quarterly

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Whales Holding ENGN

A
Artal Group S.A.
Holding
ENGN
+7.48%
3M Return
K
Kynam Capital Management, LP
Holding
ENGN
+5.06%
3M Return
V
Vestal Point Capital, LP
Holding
ENGN
+4.39%
3M Return
P
Perceptive Advisors LLC
Holding
ENGN
+3.52%
3M Return
V
VR Management, LLC
Holding
ENGN
+3.25%
3M Return
F
Fonds de solidarité FTQ
Holding
ENGN
+2.34%
3M Return

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Frequently Asked Questions

What is enGene Holdings Inc (ENGN) stock price today?

The current price of ENGN is 7.05 USD — it has decreased -18.78

What is enGene Holdings Inc (ENGN)'s business?

enGene Holdings Inc. is a clinical-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II study, which includes a cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (Cis). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. The Company is developing non-viral genetic medicines based on its DDX gene delivery platform, which allows localized delivery of multiple gene cargos directly to mucosal tissues and other organs.

What is the price predicton of ENGN Stock?

Wall Street analysts forecast ENGN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ENGN is23.88 USD with a low forecast of 10.00 USD and a high forecast of 33.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is enGene Holdings Inc (ENGN)'s revenue for the last quarter?

enGene Holdings Inc revenue for the last quarter amounts to -39.48M USD, increased 126.19

What is enGene Holdings Inc (ENGN)'s earnings per share (EPS) for the last quarter?

enGene Holdings Inc. EPS for the last quarter amounts to -25399000.00 USD, increased 28.24

How many employees does enGene Holdings Inc (ENGN). have?

enGene Holdings Inc (ENGN) has 45 emplpoyees as of March 09 2026.

What is enGene Holdings Inc (ENGN) market cap?

Today ENGN has the market capitalization of 581.47M USD.