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ENGN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
7.060
Open
6.920
VWAP
6.55
Vol
162.39K
Mkt Cap
426.72M
Low
6.220
Amount
1.06M
EV/EBITDA(TTM)
--
Total Shares
66.99M
EV
175.70M
EV/OCF(TTM)
--
P/S(TTM)
--
enGene Holdings Inc. is a clinical-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II study, which includes a cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (Cis). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. The Company is developing non-viral genetic medicines based on its DDX gene delivery platform, which allows localized delivery of multiple gene cargos directly to mucosal tissues and other organs.
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Events Timeline

(ET)
2026-03-09
07:10:00
enGene Cash and Securities Reach $312.5M, Expected to Fund Operations Until H2 2028
select
2026-02-19 (ET)
2026-02-19
16:40:00
enGene Files $400M Mixed Securities Shelf
select
2025-12-22 (ET)
2025-12-22
16:10:00
LEGEND Raises $140.1M, Cash Reserves Reach $342.4M
select
2025-12-02 (ET)
2025-12-02
07:50:00
enGene's Detalimogene Voraplasmid Selected for FDA Pilot Program
select
2025-11-13 (ET)
2025-11-13
06:14:19
enGene Prices 12.559 Million Share Spot Secondary Offering at $8.50
select

News

PRnewswire
8.5
03-19PRnewswire
Global Oncology Market Set for Rapid Growth
  • Market Size Forecast: The global oncology market is projected to reach $279.98 billion in 2026 and grow to $748.17 billion by 2035, indicating a structural shift from single-agent treatments to combination therapies and next-generation cell therapies.
  • Immuno-Oncology Expansion: The immuno-oncology segment is expected to expand from $65.22 billion in 2025 to $170.19 billion by 2032, as approvals of combination therapies convert previously resistant tumors into viable treatment targets, driving market demand.
  • Oncolytics Biotech New Data: Oncolytics Biotech will present new data at the 2026 American Association for Cancer Research Annual Meeting, indicating that its lead drug pelareorep can make tumors more susceptible to immunotherapy, particularly showing positive results in breast and gastrointestinal cancer trials.
  • Clinical Trial Progress: Oncolytics' REO 033 trial demonstrated a total survival of 27 months in second-line RAS-mutant, microsatellite-stable metastatic colorectal cancer patients, with the FDA granting Fast Track Designation, which is expected to enhance the company's position in high-value markets.
Newsfilter
7.5
03-19Newsfilter
Global Oncology Market Expected to Reach $748.17 Billion
  • Market Growth Potential: The global oncology market is valued at $279.98 billion in 2026 and is projected to reach $748.17 billion by 2035, indicating a strong trend towards a shift from single-agent treatments to combination platforms and next-generation cell therapies, potentially creating significant market opportunities for related companies.
  • Immuno-Oncology Expansion: The immuno-oncology segment is expected to grow from $65.22 billion in 2025 to $170.19 billion by 2032, as the approval of combination therapies transforms previously resistant tumors into viable treatment targets, driving rapid industry growth.
  • Oncolytics Biotech New Data: Oncolytics Biotech is set to present new mechanistic and translational data at the 2026 American Association for Cancer Research Annual Meeting, indicating that its lead drug pelareorep can enhance tumor sensitivity to immunotherapy, potentially providing crucial scientific support for the company in a competitive market.
  • Clinical Trial Progress: Oncolytics' REO 033 trial for KRAS-mutant metastatic colorectal cancer shows an overall survival of 27 months and a 33% objective response rate, with the FDA granting Fast Track Designation, which is expected to create significant market opportunities for the company.
moomoo
4.0
03-11moomoo
ENGENE HOLDINGS INC.: OPPENHEIMER LOWERS TARGET PRICE FROM $33 TO $30
  • Company Overview: Engene Holdings Inc. is a company involved in various business activities, including investments and holdings.

  • Target Price Adjustment: Oppenheimer has reduced the target price for Engene Holdings from $33 to $30.

seekingalpha
9.5
03-09seekingalpha
enGene Holdings Q1 Financial Highlights
  • Earnings Performance: enGene Holdings reported a Q1 GAAP EPS of $0.44, indicating stable profitability despite competitive market pressures.
  • Cash Position: As of January 31, 2026, the company held $312.5 million in cash, cash equivalents, and marketable securities, providing ample funding for future investments and operations.
  • Operating Expense Increase: Operating expenses for Q1 2026 totaled $31.2 million, a 17.3% increase from $26.6 million in 2025, reflecting ongoing investments in R&D and market expansion.
  • Positive Market Reaction: enGene Holdings saw a 14% surge in stock price on Friday, indicating investor optimism regarding the company's future prospects, particularly with major catalysts on the horizon.
Yahoo Finance
1.0
02-20Yahoo Finance
enGene Holdings to Participate in Multiple Investor Conferences
  • Investor Conference Schedule: enGene Holdings will present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference on February 26, 2026, showcasing its advancements in gene therapy, which is expected to attract investor interest and enhance the company's visibility.
  • Timing and Format: The company will also participate in fireside chats at the Leerink Partners Global Healthcare Conference on March 9 and the Barclays Global Healthcare Conference on March 10, scheduled for 8:00 AM and 9:00 AM respectively, aiming to engage in deeper discussions with investors to bolster market confidence.
  • Product Development Progress: enGene's lead program, detalimogene voraplasmid, is currently in the ongoing LEGEND Phase 2 trial focusing on treating patients with Non-Muscle Invasive Bladder Cancer, demonstrating the company's potential in addressing high clinical need diseases, which may lay the groundwork for future market performance.
  • Platform Technology Advantage: The product utilizes enGene's proprietary DDX platform, which enables effective penetration of mucosal tissues and delivery of various therapeutic payloads, enhancing the company's competitiveness in the gene therapy sector and is expected to drive future product line expansion.
Yahoo Finance
8.5
02-20Yahoo Finance
EnGene Files Shelf Registration for Up to $40 Million
  • Funding Initiative: EnGene filed a shelf registration statement late Thursday for a potential sale of up to $40 million, aiming to provide flexibility for future capital needs and enhance the company's financial stability.
  • Market Reaction: This move may attract investor attention, particularly in the biotech sector, where enhanced funding capabilities are often viewed as a positive signal for a company's expansion in R&D and marketing.
  • Strategic Implications: By establishing a funding channel, EnGene can more effectively respond to market changes and industry competition, thereby improving its competitiveness in the biopharmaceutical market.
  • Future Outlook: The implementation of this funding plan will provide EnGene with the necessary financial support to drive product development and market expansion, further solidifying its position in the industry.
Wall Street analysts forecast ENGN stock price to rise
8 Analyst Rating
Wall Street analysts forecast ENGN stock price to rise
7 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
10.00
Averages
23.88
High
33.00
Current: 0.000
sliders
Low
10.00
Averages
23.88
High
33.00
UBS
David Dai
Neutral
downgrade
$10 -> $9
AI Analysis
2026-03-22
Reason
UBS
David Dai
Price Target
$10 -> $9
AI Analysis
2026-03-22
downgrade
Neutral
Reason
UBS analyst David Dai lowered the firm's price target on enGene to $9 from $10 and keeps a Neutral rating on the shares following the fiscal Q1 report. The firm cites increased spending due to the LEGEND trial and launch of detalimogene in 2027 for the target cut.
Oppenheimer
Oppenheimer
Outperform
to
Outperform
downgrade
$33 -> $30
2026-03-11
Reason
Oppenheimer
Oppenheimer
Price Target
$33 -> $30
2026-03-11
downgrade
Outperform
to
Outperform
Reason
Oppenheimer lowered the firm's price target on enGene to $30 from $33 and keeps an Outperform rating on the shares. The firm notes the company announced that it plans to present updated results from the pivotal cohort of its ongoing LEGEND trial in NMIBC at a medical conference this spring - Oppenheimer presumes the annual AUA meeting in mid-May. The firm caught up with management, who indicated that the content will most likely feature six-month complete response rates, as well as CR rates at any time, from the vast majority of this cohort's subjects. Oppenheimer looks toward the second half of 2026 for 12-month data as well as potential BLA submission.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ENGN
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Valuation Metrics

The current forward P/E ratio for enGene Holdings Inc (ENGN.O) is -3.71, compared to its 5-year average forward P/E of -3.05. For a more detailed relative valuation and DCF analysis to assess enGene Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.05
Current PE
-3.71
Overvalued PE
-0.13
Undervalued PE
-5.97

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.08
Current EV/EBITDA
-2.81
Overvalued EV/EBITDA
1.25
Undervalued EV/EBITDA
-5.40

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding ENGN

V
VR Management, LLC
Holding
ENGN
+5.88%
3M Return
V
Vestal Point Capital, LP
Holding
ENGN
+1.57%
3M Return
A
Artal Group S.A.
Holding
ENGN
+0.12%
3M Return
P
Perceptive Advisors LLC
Holding
ENGN
-0.06%
3M Return
K
Kynam Capital Management, LP
Holding
ENGN
-0.98%
3M Return
B
Braidwell LP
Holding
ENGN
-1.04%
3M Return

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Frequently Asked Questions

What is enGene Holdings Inc (ENGN) stock price today?

The current price of ENGN is 6.37 USD — it has decreased -8.48

What is enGene Holdings Inc (ENGN)'s business?

enGene Holdings Inc. is a clinical-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II study, which includes a cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (Cis). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. The Company is developing non-viral genetic medicines based on its DDX gene delivery platform, which allows localized delivery of multiple gene cargos directly to mucosal tissues and other organs.

What is the price predicton of ENGN Stock?

Wall Street analysts forecast ENGN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ENGN is23.88 USD with a low forecast of 10.00 USD and a high forecast of 33.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is enGene Holdings Inc (ENGN)'s revenue for the last quarter?

enGene Holdings Inc revenue for the last quarter amounts to -31.18M USD, increased 17.18

What is enGene Holdings Inc (ENGN)'s earnings per share (EPS) for the last quarter?

enGene Holdings Inc. EPS for the last quarter amounts to -29056000.00 USD, increased 11.78

How many employees does enGene Holdings Inc (ENGN). have?

enGene Holdings Inc (ENGN) has 45 emplpoyees as of March 30 2026.

What is enGene Holdings Inc (ENGN) market cap?

Today ENGN has the market capitalization of 426.72M USD.