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ALKS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
45.760
Open
45.250
VWAP
44.91
Vol
7.75M
Mkt Cap
7.50B
Low
43.980
Amount
348.12M
EV/EBITDA(TTM)
36.14
Total Shares
166.68M
EV
8.50B
EV/OCF(TTM)
33.17
P/S(TTM)
4.84
Alkermes plc is an Ireland-based global biopharmaceutical company that seeks to develop medicines in the field of neuroscience. The Company has a portfolio of commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy. Its pipeline includes late-stage clinical candidates in development for narcolepsy and idiopathic hypersomnia, and orexin 2 receptor agonists in early clinical development for other neurological disorders, including attention-deficit hyperactivity disorder (ADHD) and fatigue associated with multiple sclerosis and Parkinson’s disease. The Company's pipeline includes Olanzapine and samidorphan, Alixorexton, ALKS 4510, ALKS 7290, and Valiloxybate. Its LUMRYZ (sodium oxybate) for extended-release oral suspension is a central nervous system depressant indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients seven years of age and older with narcolepsy.
Show More

Events Timeline

(ET)
2026-06-17
20:30:00
Federal Reserve Keeps Rates Unchanged, Markets Rebound
select
2026-06-17
16:30:00
Alkermes Announces Positive Results for Alixorexton in Type 2 Narcolepsy Patients
select
2026-06-15 (ET)
2026-06-15
07:31:00
Alkermes' alixorexton Granted Orphan Drug Designation
select
2026-06-11 (ET)
2026-06-11
12:30:00
Alkermes' Alixorexton Granted FDA Orphan Designation
select
link
2026-06-04 (ET)
2026-06-04
07:20:00
Alkermes to Present New Sleep Medicine Data at SLEEP 2026
select
2026-05-12 (ET)
2026-05-12
07:20:00
Alkermes Reports Positive Results for LUMRYZ in Phase 3 Study
select

News

seekingalpha
2.0
06-17seekingalpha
Alkermes Shares Plunge 31% After Phase 2 Study Results
  • Clinical Trial Results: Alkermes reported results from its Phase 2 study of alixorexton for narcolepsy type 2, achieving dual primary endpoints; however, shares plummeted approximately 31% in after-hours trading, indicating a negative market reaction despite the trial's success.
  • Primary Endpoint Achievement: The Vibrance-2 trial demonstrated improvements at week eight on the Maintenance of Wakefulness Test and Epworth Sleepiness Scale compared to placebo, with patient-reported wakefulness improvements maintained through a five-week open-label extension, suggesting the drug's potential efficacy.
  • Adverse Events: No serious treatment-emergent adverse events were reported during the trial, which may bolster investor confidence in the safety profile of alixorexton, although the stock still faced downward pressure.
  • Future Research Plans: Alkermes has initiated a Phase 3 program to examine once-daily and split dosing regimens of alixorexton, reflecting the company's commitment to the long-term development of the drug, despite the short-term negative market response.
Newsfilter
9.0
06-17Newsfilter
Alkermes Reports Positive Phase 2 Results for Alixorexton in Narcolepsy Type 2
  • Clinical Trial Success: Alkermes' alixorexton achieved its primary endpoints in the Vibrance-2 phase 2 study involving 93 patients with narcolepsy type 2, demonstrating statistically significant improvements in the Maintenance of Wakefulness Test (MWT) and Epworth Sleepiness Scale (ESS) compared to placebo, indicating its substantial potential in treating narcolepsy.
  • Sustained Improvement: Patient-reported enhancements in wakefulness and cognition were maintained throughout the 13-week study, with mean sleep latencies of 14 minutes and 16 minutes for the 14 mg and 18 mg doses respectively at week eight, showcasing significant clinical relevance.
  • Good Safety Profile: Alixorexton exhibited favorable tolerability across all tested doses (10 mg, 14 mg, and 18 mg), with over 95% of participants completing the eight-week treatment and no serious treatment-emergent adverse events reported, underscoring its safety in clinical applications.
  • Future Development Potential: Following the positive results from Vibrance-2, Alkermes has initiated a global phase 3 program to evaluate alixorexton in patients with narcolepsy type 1 and type 2, highlighting the drug's innovative potential and market prospects in the neuroscience field.
NASDAQ.COM
9.0
06-15NASDAQ.COM
Alkermes Receives Orphan Drug Designation for Alixorexton
  • Orphan Drug Designation: Alkermes' alixorexton has received orphan drug designation from the FDA for idiopathic hypersomnia, marking a significant milestone in the drug development process that could expedite market access.
  • European Commission Approval: The drug also received orphan drug designation from the European Commission for narcolepsy treatment, which will aid the company's expansion in the European market and enhance its international competitiveness.
  • Clinical Trial Progress: Alkermes is currently enrolling patients in the phase 3 Brilliance Studies and completing the phase 2 Vibrance-3 study for alixorexton, with completion expected this year, which could lead to potential revenue growth for the company.
  • Market Reaction: Alkermes shares are down 0.18% to $44.20 in pre-market trading on Nasdaq, reflecting a cautious market response to the drug development progress, which may impact investor confidence.
seekingalpha
9.0
06-11seekingalpha
Alkermes Receives FDA Orphan Drug Designation
  • Orphan Drug Designation: The US FDA has granted orphan drug designation to Alkermes' alixorexton for idiopathic hypersomnia, highlighting the company's innovative potential in the sleep medicine sector.
  • Drug Development Stage: Alixorexton is currently in phase 2 clinical trials as an oral orexin 2 receptor agonist, aimed at alleviating daytime sleepiness symptoms, which could introduce a new treatment option to the market.
  • Market Demand Context: Idiopathic hypersomnia is characterized by difficulty waking up in the morning and extreme daytime sleepiness, and as awareness of sleep health increases, the successful development of this drug will meet the growing market demand.
  • Strategic Company Implications: The FDA's orphan drug designation not only enhances Alkermes' reputation in the sleep medicine field but may also provide funding and market support for its future commercialization efforts, strengthening its competitive position in the CNS pharmaceutical market.
seekingalpha
9.0
05-12seekingalpha
Alkermes' Lumryz Achieves Key Trial Milestone for Sleep Disorder
  • Trial Success: Alkermes announced that its sleep disorder therapy Lumryz met the primary goal in a late-stage trial for idiopathic hypersomnia, with patients showing statistically significant improvements in excessive daytime sleepiness, indicating strong market potential for the drug.
  • Safety Profile Confirmed: The Revitalyz study reaffirmed Lumryz's safety profile consistent with prior data, with no new safety signals reported, which supports its future market rollout and mitigates regulatory risks.
  • Future Plans: Alkermes intends to present the trial data at an upcoming medical event and plans to submit a supplemental new drug application by the end of 2026 to seek label expansion for Lumryz in the U.S., further enhancing its competitive position.
  • Market Potential: With increasing demand for treatments for idiopathic hypersomnia, Alkermes' Lumryz is poised to play a significant role in the sleep medicine sector, driving future revenue growth and market share expansion for the company.
seekingalpha
9.5
05-04seekingalpha
Alkermes Q1 Earnings Announcement Scheduled
  • Earnings Release Date: Alkermes is set to announce its Q1 earnings on May 5 before market open, with a consensus EPS estimate of -$0.04, reflecting a significant year-over-year decline of 130.8%, indicating potential profitability challenges for the company.
  • Revenue Expectations: The anticipated revenue for Q1 is $361.38 million, representing a 17.9% year-over-year increase, suggesting that despite challenges, Alkermes may still exhibit revenue growth potential, possibly reflecting stable product demand.
  • Historical Performance Review: Over the past year, Alkermes has only beaten EPS estimates 25% of the time while exceeding revenue estimates 75% of the time, indicating relative stability in revenue but a need for improvement in profitability.
  • Estimate Revision Trends: In the last three months, EPS estimates have seen no upward or downward revisions, while revenue estimates experienced 10 upward and 6 downward revisions, indicating market divergence in expectations for the company's future revenue.
Wall Street analysts forecast ALKS stock price to rise
12 Analyst Rating
Wall Street analysts forecast ALKS stock price to rise
10 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
37.00
Averages
46.20
High
58.00
Current: 0.000
sliders
Low
37.00
Averages
46.20
High
58.00
H.C. Wainwright
H.C. Wainwright
Neutral
maintain
$43
AI Analysis
2026-06-18
New
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$43
AI Analysis
2026-06-18
New
maintain
Neutral
Reason
H.C. Wainwright says Alkermes' detailed results from the Vibrance-2 study provide additional insights into the broader effects of alixorexton on narcolepsy type 2 patients. In addition to the previously reported improvements in the maintenance of wakefulness test and Epworth Sleepiness Scale, new exploratory endpoints demonstrated enhancements in fatigue and cognitive function at higher doses, the analyst tells investors in a research note. H.C. Wainwright views the data as "encouraging signals" that OX2R agonism may provide functional improvements, including fatigue, brain fog, and daytime functioning, beyond improvements in wakefulness alone. The findings are supportive of the Alkermes' work in attention-deficit/hyperactivity disorder with ALKS-7290, adds the firm. It keeps a Neutral rating on Alkermes with a $43 price target. The stock in premarket trading is down 1% to $44.09.
Baird
Luke Herrmann
Outperform
maintain
$45 -> $48
2026-05-13
Reason
Baird
Luke Herrmann
Price Target
$45 -> $48
2026-05-13
maintain
Outperform
Reason
Baird analyst Luke Herrmann raised the firm's price target on Alkermes to $48 from $45 and keeps an Outperform rating on the shares. The firm updated its model following positive IH Phase 3 data setting up sNDA by the end of 2026.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ALKS
Unlock Now

Valuation Metrics

The current forward P/E ratio for Alkermes Plc (ALKS.O) is 117.65, compared to its 5-year average forward P/E of 100.90. For a more detailed relative valuation and DCF analysis to assess Alkermes Plc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
100.90
Current PE
117.65
Overvalued PE
249.27
Undervalued PE
-47.47

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
10.97
Current EV/EBITDA
245.29
Overvalued EV/EBITDA
89.90
Undervalued EV/EBITDA
-67.96

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.54
Current PS
3.97
Overvalued PS
4.35
Undervalued PS
2.72

Financials

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Whales Holding ALKS

C
Commodore Capital LP
Holding
ALKS
+25.88%
3M Return
A
Avoro Capital Advisors LLC
Holding
ALKS
+24.79%
3M Return
D
Deep Track Capital, LP
Holding
ALKS
+16.77%
3M Return
R
RTW Investments, LP
Holding
ALKS
+10.61%
3M Return
B
Baker Bros. Advisors LP
Holding
ALKS
+10.49%
3M Return
S
Soleus Capital Management, L.P.
Holding
ALKS
+9.90%
3M Return

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Frequently Asked Questions

What is Alkermes Plc (ALKS) stock price today?

The current price of ALKS is 44.99 USD — it has increased 1.08

What is Alkermes Plc (ALKS)'s business?

Alkermes plc is an Ireland-based global biopharmaceutical company that seeks to develop medicines in the field of neuroscience. The Company has a portfolio of commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy. Its pipeline includes late-stage clinical candidates in development for narcolepsy and idiopathic hypersomnia, and orexin 2 receptor agonists in early clinical development for other neurological disorders, including attention-deficit hyperactivity disorder (ADHD) and fatigue associated with multiple sclerosis and Parkinson’s disease. The Company's pipeline includes Olanzapine and samidorphan, Alixorexton, ALKS 4510, ALKS 7290, and Valiloxybate. Its LUMRYZ (sodium oxybate) for extended-release oral suspension is a central nervous system depressant indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients seven years of age and older with narcolepsy.

What is the price predicton of ALKS Stock?

Wall Street analysts forecast ALKS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALKS is46.20 USD with a low forecast of 37.00 USD and a high forecast of 58.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Alkermes Plc (ALKS)'s revenue for the last quarter?

Alkermes Plc revenue for the last quarter amounts to 392.91M USD, increased 28.19

What is Alkermes Plc (ALKS)'s earnings per share (EPS) for the last quarter?

Alkermes Plc. EPS for the last quarter amounts to -0.40 USD, decreased -407.69

How many employees does Alkermes Plc (ALKS). have?

Alkermes Plc (ALKS) has 2050 emplpoyees as of June 20 2026.

What is Alkermes Plc (ALKS) market cap?

Today ALKS has the market capitalization of 7.50B USD.