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ELVN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
40.935
Open
40.650
VWAP
39.84
Vol
747.89K
Mkt Cap
2.52B
Low
39.020
Amount
29.80M
EV/EBITDA(TTM)
--
Total Shares
60.90M
EV
2.02B
EV/OCF(TTM)
--
P/S(TTM)
--
Enliven Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule inhibitors to help patients with cancer. It is advancing two parallel lead product candidates, ELVN-001 and ELVN-002, and pursuing several additional research stage opportunities that align with its development approach. Its first product candidate, ELVN-001, is a potent, highly selective, small molecule kinase inhibitor designed to specifically target the breakpoint cluster region-Abelson (BCR-ABL) gene fusion, the oncogenic driver for patients with chronic myeloid leukemia. Its second product candidate, ELVN-002, is a potent, highly selective, central nervous system penetrant and irreversible human epidermal growth factor receptor 2 (HER2) inhibitor with activity against wild type HER2 and various HER2 mutations. ELVN-002 is designed to inhibit wild type HER2 and key mutations of HER2, while sparing wild-type EGFR and avoiding EGFR-related toxicities.
Show More

Events Timeline

(ET)
2026-05-12
10:00:00
Enliven Therapeutics Releases ELVN-001 Clinical Trial Data
select
2026-05-07 (ET)
2026-05-07
16:50:00
Company Cash and Securities Total $452.4M, Expected to Last into H1 2029
select
2026-03-26 (ET)
2026-03-26
12:10:00
Enliven Stock Rises 11% to $39.45
select
2026-03-25 (ET)
2026-03-25
10:10:00
Merck Acquires Terns Pharmaceuticals for $6.7B, Focuses on CML Treatment
select

News

NASDAQ.COM
8.0
05-29NASDAQ.COM
Surge in Options Trading Volume for Apple and Coinbase
  • Apple Options Volume: Apple Inc (AAPL) saw options trading volume of 1.1 million contracts, equivalent to approximately 113 million shares, representing a 225.4% increase over its average daily trading volume of 50.2 million shares in the past month, indicating strong market interest in its future performance.
  • High Strike Activity: Notably, the $315 strike call option expiring on May 29, 2026, recorded a trading volume of 143,582 contracts today, representing about 14.4 million underlying shares, suggesting a significant bullish sentiment among investors regarding Apple's stock price.
  • Coinbase Options Dynamics: Coinbase Global Inc (COIN) experienced options trading volume of 204,154 contracts, translating to approximately 20.4 million shares, which is 213.4% of its average daily trading volume of 9.6 million shares over the past month, reflecting positive market sentiment towards its future trajectory.
  • Bullish Call Options: The $190 strike call option expiring on May 29, 2026, saw a trading volume of 13,657 contracts today, equivalent to about 1.4 million underlying shares, indicating investor optimism about Coinbase's future performance.
Fool
8.5
05-13Fool
Avidity Partners Increases Stake in Enliven Therapeutics
  • Increased Holdings: Avidity Partners Management acquired an additional 259,700 shares of Enliven Therapeutics in Q1 2026, valued at approximately $7.19 million, indicating strong confidence in the company's future potential.
  • Market Capitalization Growth: As of March 31, 2026, Enliven's market capitalization reached $2.65 billion, with its stock price increasing by 120% over the past year, significantly outperforming the S&P 500's 26% rise, reflecting positive market expectations for its products.
  • R&D Progress: Enliven is advancing its clinical trials for small molecule kinase inhibitors, particularly ELVN-001 for chronic myeloid leukemia, with new clinical data expected by mid-2026, further bolstering investor confidence.
  • Strong Financial Position: As of Q1 2026, Enliven held approximately $452 million in cash and marketable securities, which is projected to fund operations into the first half of 2029, demonstrating a solid financial foundation in the clinical-stage biopharmaceutical sector.
stocktwits
2.0
05-12stocktwits
Enliven's ELVN-001 Shows Promising Trial Results and Analyst Support
  • Trial Results: The ENABLE trial results as of December 22, 2025, indicate that ELVN-001 shows promising efficacy and a favorable safety profile in heavily pretreated chronic myeloid leukemia patients, with 76% of the 141 enrolled patients still on treatment and a median treatment duration of 31.7 weeks, demonstrating sustained anti-CML activity.
  • Future Trial Plans: Enliven is preparing to advance ELVN-001 into a pivotal late-stage trial in the second half of 2026, reflecting the company's confidence in the drug's potential and its strategic importance in the market.
  • Analyst Rating Upgrade: Guggenheim Securities initiated coverage of Enliven with a ‘Buy’ rating and an $80 price target, viewing ELVN-001 as a potential best-in-class oral therapy for CML, while noting that the current valuation does not fully capture its commercial opportunity.
  • Positive Market Reaction: Following the announcement of positive data presentation at an upcoming conference, Enliven's stock surged 7%, indicating strong market optimism regarding its development progress, with the stock having more than doubled over the past 12 months, reflecting investor confidence in future growth.
PRnewswire
9.0
05-12PRnewswire
Enliven Therapeutics Reports Positive Data on ELVN-001 for CML
  • Clinical Trial Progress: In the ENABLE clinical trial, ELVN-001 demonstrated a favorable safety and tolerability profile in 141 patients with a median treatment duration of approximately 32 weeks, indicating its potential application in chronic myeloid leukemia (CML).
  • Efficacy Data Update: In the 80 mg QD Phase 1b cohort, the cumulative major molecular response (MMR) rate was 47%, with 38% of patients achieving MMR by 24 weeks, showcasing ELVN-001's robust anti-CML activity in heavily pretreated patients.
  • Upcoming Conference Data: Enliven is set to present updated data at the 2026 European Hematology Association Congress, which is expected to further enhance the clinical prospects of ELVN-001, particularly in patients resistant to existing tyrosine kinase inhibitors (TKIs).
  • Strategic Implications: ELVN-001's distinct binding mode and complementary mechanism to allosteric inhibitors may position it as a best-in-class option for CML treatment, further solidifying Enliven's market position in the biopharmaceutical sector.
Newsfilter
9.0
05-12Newsfilter
Enliven Therapeutics Announces Updated Clinical Data for ELVN-001
  • Clinical Trial Progress: As of December 22, 2025, 141 patients with chronic myeloid leukemia (CML) were enrolled in the Phase 1 trial of ELVN-001, with 76% remaining on treatment for an average of 31.7 weeks, demonstrating favorable safety and tolerability in heavily pretreated patients.
  • Efficacy Data Update: In the initial 80 mg QD Phase 1b cohort, 47% of patients achieved major molecular response (MMR), while in the randomized 60 mg and 120 mg QD cohorts, 69% achieved MMR, indicating ELVN-001's potential in treating refractory CML patients.
  • Safety Analysis: ELVN-001 exhibited a favorable safety profile, with less than 10% of patients experiencing dose reductions due to treatment-emergent adverse events, and only 6.4% discontinuing treatment due to adverse events, reinforcing its advantages as a selective kinase inhibitor.
  • Future Outlook: Enliven plans to present additional data at the European Hematology Association Congress on June 11, 2026, highlighting ELVN-001's prospects as a potential best-in-class therapy, particularly in targeting the BCR::ABL1 gene fusion in CML treatment.
NASDAQ.COM
5.0
03-28NASDAQ.COM
Helen Collins Sells 40,000 Shares of Enliven Therapeutics
  • Transaction Overview: Helen Louise Collins exercised and sold 40,000 shares of Common Stock between March 9-10, 2026, generating approximately $1.20 million at a weighted average price of $30.07 per share, reducing her direct holdings by 61.54% from 65,000 to 25,000 shares.
  • Market Reaction Analysis: Following Collins' sale, Enliven Therapeutics' stock closed at $30.24 on March 10, 2026, indicating positive market sentiment towards the company's future potential, despite Collins selling at a lower price than the subsequent market value.
  • Clinical Progress and Competition: Enliven Therapeutics focuses on developing small-molecule therapies for cancer, with its CML candidate ELVN-001 showing a 47% major molecular response rate at 24 weeks, although Merck's acquisition of Terns Pharmaceuticals may spark interest in acquiring Enliven.
  • Investor Caution: Despite Enliven Therapeutics' potential in the biotech sector, the Motley Fool Stock Advisor analyst team did not include it in their current list of top investment stocks, advising investors to carefully consider market dynamics before making investment decisions.
Wall Street analysts forecast ELVN stock price to rise
4 Analyst Rating
Wall Street analysts forecast ELVN stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
35.00
Averages
40.67
High
48.00
Current: 0.000
sliders
Low
35.00
Averages
40.67
High
48.00
Guggenheim
NULL
to
Buy
initiated
$80
AI Analysis
2026-05-12
Reason
Guggenheim
Price Target
$80
AI Analysis
2026-05-12
initiated
NULL
to
Buy
Reason
Guggenheim last night initiated coverage of Enliven with a Buy rating and $80 price target. The company is focused on the discovery and development of small molecule therapeutics, the analyst tells investors in a research note. The firm says Enliven's lead product candidate ELVN-001 is a "potential best in-class" oral BCR-ABL inhibitor for chronic myeloid leukemia that should be Phase 3-ready this summer. The stock's current valuation does not appreciate the size of the opportunity, strategic validation, and reasonable risk-adjusted market share assumptions for ELVN-001, contends Guggenheim.
Guggenheim
Buy
initiated
$80
2026-05-11
Reason
Guggenheim
Price Target
$80
2026-05-11
initiated
Buy
Reason
Guggenheim initiated coverage of Enliven with a Buy rating and $80 price target.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ELVN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Enliven Therapeutics Inc (ELVN.O) is 0.00, compared to its 5-year average forward P/E of -9.29. For a more detailed relative valuation and DCF analysis to assess Enliven Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-9.29
Current PE
0.00
Overvalued PE
-7.18
Undervalued PE
-11.40

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.66
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-2.27
Undervalued EV/EBITDA
-7.05

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
106677.84
Current PS
302769.94
Overvalued PS
208974.86
Undervalued PS
4380.82

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Whales Holding ELVN

N
Novo Holdings A/S
Holding
ELVN
+20.39%
3M Return
C
Commodore Capital LP
Holding
ELVN
+18.34%
3M Return
F
Fairmount Funds Management LLC
Holding
ELVN
+14.62%
3M Return
V
VR Management, LLC
Holding
ELVN
+9.81%
3M Return
R
Rock Springs Capital Management LP
Holding
ELVN
+7.73%
3M Return
L
Logos Global Management, L.P.
Holding
ELVN
+6.22%
3M Return

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Frequently Asked Questions

What is Enliven Therapeutics Inc (ELVN) stock price today?

The current price of ELVN is 39.57 USD — it has decreased -2.66

What is Enliven Therapeutics Inc (ELVN)'s business?

Enliven Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule inhibitors to help patients with cancer. It is advancing two parallel lead product candidates, ELVN-001 and ELVN-002, and pursuing several additional research stage opportunities that align with its development approach. Its first product candidate, ELVN-001, is a potent, highly selective, small molecule kinase inhibitor designed to specifically target the breakpoint cluster region-Abelson (BCR-ABL) gene fusion, the oncogenic driver for patients with chronic myeloid leukemia. Its second product candidate, ELVN-002, is a potent, highly selective, central nervous system penetrant and irreversible human epidermal growth factor receptor 2 (HER2) inhibitor with activity against wild type HER2 and various HER2 mutations. ELVN-002 is designed to inhibit wild type HER2 and key mutations of HER2, while sparing wild-type EGFR and avoiding EGFR-related toxicities.

What is the price predicton of ELVN Stock?

Wall Street analysts forecast ELVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ELVN is40.67 USD with a low forecast of 35.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Enliven Therapeutics Inc (ELVN)'s revenue for the last quarter?

Enliven Therapeutics Inc revenue for the last quarter amounts to -27.82M USD, decreased -12.21

What is Enliven Therapeutics Inc (ELVN)'s earnings per share (EPS) for the last quarter?

Enliven Therapeutics Inc. EPS for the last quarter amounts to -19291000.00 USD, decreased -20.11

How many employees does Enliven Therapeutics Inc (ELVN). have?

Enliven Therapeutics Inc (ELVN) has 60 emplpoyees as of May 30 2026.

What is Enliven Therapeutics Inc (ELVN) market cap?

Today ELVN has the market capitalization of 2.52B USD.