enGene Holdings Secures $125 Million Loan Agreement with Hercules Capital
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1h ago
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Source: Businesswire
- Financing Enhancement: enGene has entered into an amended loan agreement with Hercules Capital for up to $125 million in non-dilutive capital, strengthening the company's financial flexibility in preparation for its planned Biologics License Application (BLA) to the FDA in the second half of 2026.
- Clinical Trial Support: The loan agreement includes an initial $25 million for refinancing existing debt, with an additional $75 million available based on clinical and regulatory milestones, ensuring continued R&D in high-risk non-muscle invasive bladder cancer (NMIBC) treatment.
- Significant Market Potential: Approximately 75-80% of new bladder cancer diagnoses are NMIBC, with BCG-unresponsive patients facing a 50-70% recurrence rate, making enGene's detalimogene voraplasmid a promising innovative bladder-sparing treatment option to meet urgent market needs.
- Deepening Strategic Partnership: Hercules Capital's support underscores its commitment as a long-term capital partner and highlights the importance of financing innovative life sciences companies, aiding enGene in the potential commercial launch of detalimogene in 2027.
Analyst Views on ENGN
Wall Street analysts forecast ENGN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ENGN is 23.75 USD with a low forecast of 10.00 USD and a high forecast of 33.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
8 Analyst Rating
7 Buy
1 Hold
0 Sell
Strong Buy
Current: 9.310
Low
10.00
Averages
23.75
High
33.00
Current: 9.310
Low
10.00
Averages
23.75
High
33.00
About ENGN
enGene Holdings Inc. is a clinical-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II study, which includes a cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (Cis). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. The Company is developing non-viral genetic medicines based on its DDX gene delivery platform, which allows localized delivery of multiple gene cargos directly to mucosal tissues and other organs.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
