
CTMX
CytomX Therapeutics Inc
- Overview
- Forecast
- Valuation
- Earnings

Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
2.500
Open
2.420
VWAP
2.43
Vol
676.08K
Mkt Cap
375.74M
Low
2.380
Amount
1.64M
EV/EBITDA(TTM)
7.86
Total Shares
77.92M
EV
295.86M
EV/OCF(TTM)
--
P/S(TTM)
1.39
CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q2
FY2025Q3
FY2025Q4
19.10M
-23.95%
--
--
16.13M
-51.77%
--
--
16.13M
-57.67%
--
--
Estimates Revision
The market is revising Downward the revenue expectations for CytomX Therapeutics, Inc. (CTMX) for FY2025, with the revenue forecasts being adjusted by -6.9% over the past three months. During the same period, the stock price has changed by 218.04%.
Revenue Estimates for FY2025
Revise Downward

-6.9%
In Past 3 Month
Stock Price
Go Up

+218.04%
In Past 3 Month
3 Analyst Rating

88.68% Upside
Wall Street analysts forecast CTMX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CTMX is 4.50 USD with a low forecast of 3.50 USD and a high forecast of 5.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Buy
0 Hold
0 Sell
Strong Buy

88.68% Upside
Current: 2.385

Low
3.50
Averages
4.50
High
5.00

88.68% Upside
Current: 2.385

Low
3.50
Averages
4.50
High
5.00
H.C. Wainwright
H.C. Wainwright
Neutral -> Buy
upgrade
$5
2025-05-15
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$5
2025-05-15
upgrade
Neutral -> Buy
Reason
Piper Sandler
Edward A. Tenthoff
upgrade
$5
2025-05-15
Reason
Piper Sandler
Edward A. Tenthoff
Price Target
$5
2025-05-15
upgrade
Reason
Piper Sandler analyst Edward A. Tenthoff raised the firm's price target on CytomX Therapeutics to $5 from $2.50 and keeps an Overweight rating on the shares after the company reported positive initial Phase I CX-2051 data in 3rd-line+ metastatic colorectal cancer. The results compare favorably to currently approved agents. Importantly, CytomX's masking technology allowed for a clean safety profile with no Grade 4+ TRAEs. If the early efficacy signal holds, Piper expects CytomX will meet with FDA and initiate a potentially registrational Phase II study in the first half of 2026.
Piper Sandler
Joseph Catanzaro
Buy
Maintains
$3.25 → $2.5
2025-04-14
Reason
Piper Sandler
Joseph Catanzaro
Price Target
$3.25 → $2.5
2025-04-14
Maintains
Buy
Reason
Piper Sandler analyst Edward A. Tenthoff assumed coverage of CytomX Therapeutics with an Overweight rating with a price target of $2.50, down from $3.25. The firm notes CytomX is enrolling the 7th cohort in the Phase I dose-escalation study of CX-2051 in metastatic colorectal cancer with initial data in Q2 2025. Clean safety data will validate this masked EpCAM ADC with any efficacy signal including stable disease a positive in lateline CRC patients, adds Piper. CytomX is also conducting Phase I dose-escalation of Probody masked interferon-alpha2b CX-801 i metastatic melanoma with initial PD data in the second half of 2025 and efficacy data in 2026.
HC Wainwright & Co.
Mitchell Kapoor
Hold
Reiterates
n/a
2025-03-07
Reason
HC Wainwright & Co.
Mitchell Kapoor
Price Target
n/a
2025-03-07
Reiterates
Hold
Reason
HC Wainwright & Co.
Mitchell Kapoor
Hold
Reiterates
n/a
2025-01-07
Reason
HC Wainwright & Co.
Mitchell Kapoor
Price Target
n/a
2025-01-07
Reiterates
Hold
Reason
HC Wainwright & Co.
Mitchell Kapoor
Hold
Reiterates
n/a
2024-11-11
Reason
HC Wainwright & Co.
Mitchell Kapoor
Price Target
n/a
2024-11-11
Reiterates
Hold
Reason
See All Ratings
Valuation Metrics
The current forward P/E ratio for CytomX Therapeutics Inc (CTMX.O) is -9.81, compared to its 5-year average forward P/E of 13.60. For a more detailed relative valuation and DCF analysis to assess CytomX Therapeutics Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
13.60
Current PE
-9.81
Overvalued PE
84.18
Undervalued PE
-56.97
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-1.81
Current EV/EBITDA
-54.92
Overvalued EV/EBITDA
8.13
Undervalued EV/EBITDA
-11.75
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

Overvalued
5Y Average PS
2.82
Current PS
5.38
Overvalued PS
4.74
Undervalued PS
0.91
Financials
Annual
Quarterly
FY2025Q1
YoY :
+22.80%
50.92M
Total Revenue
FY2025Q1
YoY :
+94.06%
22.62M
Operating Profit
FY2025Q1
YoY :
+70.58%
23.53M
Net Income after Tax
FY2025Q1
YoY :
+58.82%
0.27
EPS - Diluted
FY2025Q1
YoY :
-19.11%
-21.16M
Free Cash Flow
FY2025Q1
YoY :
0.00%
100.00
Gross Profit Margin - %
FY2025Q1
YoY :
-28.68%
-55.26
FCF Margin - %
FY2025Q1
YoY :
+38.91%
46.20
Net Margin - %
Trading Trends
Insider
Insiders areSelling! The selling amount has increased 359.35% over the last month.
Sold
0-3
Months
220.0K
USD
4
3-6
Months
47.9K
USD
5
6-9
Months
0.0
USD
0
0-12
Months
34.9K
USD
5
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds areBuying! The buying amount has increased 1199% over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
0.0
Volume
0
6-9
Months
0.0
Volume
0
0-12
Months
0.0
Volume
0
Bought
0-3
1
13.0M
Volume
Months
3-6
1
1,000K
Volume
Months
6-9
0
0.0
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders areSelling! The selling amount has increased 359.35% over the last month.
Sold
0-3
Months
220.0K
USD
4
3-6
Months
47.9K
USD
5
6-9
Months
0.0
USD
0
0-12
Months
34.9K
USD
5
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
CTMX News & Events
Events Timeline
2025-05-19 (ET)
2025-05-19
08:11:44
CytomX Therapeutics announces first patient dosed in Phase 1 study of CX-801

2025-05-12 (ET)
2025-05-12
07:24:54
CytomX Therapeutics 76.9M share Secondary priced at $1.30

2025-05-12
06:19:48
CytomX reports results from interim Phase 1 data for CX-2051

Sign Up For More Events
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News
9.0
07-09NewsfilterBreaking Through: Systemic Genetic Medicines for Hard-to-Treat Cancers
3.0
07-06Yahoo FinanceDo CytomX Therapeutics' (NASDAQ:CTMX) Earnings Warrant Your Attention?
2.0
05-28BenzingaHeico, Monro, Abercrombie & Fitch, Joby Aviation And Other Big Stocks Moving Higher On Wednesday
Sign Up For More News
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FAQ

What is CytomX Therapeutics Inc (CTMX) stock price today?
The current price of CTMX is 2.385 USD — it has increased 0.21 % in the last trading day.

What is CytomX Therapeutics Inc (CTMX)'s business?

What is the price predicton of CTMX Stock?

What is CytomX Therapeutics Inc (CTMX)'s revenue for the last quarter?

What is CytomX Therapeutics Inc (CTMX)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for CytomX Therapeutics Inc (CTMX)'s fundamentals?

How many employees does CytomX Therapeutics Inc (CTMX). have?
