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OCS Overview

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Intellectia

Loading chart...

High
29.150
Open
29.130
VWAP
27.79
Vol
368.41K
Mkt Cap
1.58B
Low
26.935
Amount
10.24M
EV/EBITDA(TTM)
--
Total Shares
57.98M
EV
1.36B
EV/OCF(TTM)
--
P/S(TTM)
--
Oculis Holding AG is a Switzerland-based company primally engaged in biotechnology sector. The Company is focused on the development of eye disease treatment for ophthalmology. It includes OCS-01, based on the OPTIREACH technology, a topical retinal candidate for diabetic macular edema (DME); OCS-02, a topical biologic candidate for dry eye disease (DED) in a form of a single chain antibody fragment; and OCS-05, a disease modifying candidate for acute optic neuritis (AON) and for other neuro-ophtha disorders such as glaucoma, diabetic retinopathy, geographic atrophy, and neurotrophic keratitis. The Company have operations in the USA, Europe and China. Ocullis deliver treatments to patients worldwide.
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Events Timeline

(ET)
2026-03-04
16:30:00
Oculis Files Automatic Mixed Securities Shelf
select
2026-03-03 (ET)
2026-03-03
16:30:00
Oculis CEO Predicts 2026 Will Be Landmark Year
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2026-01-06 (ET)
2026-01-06
09:00:00
Stock Futures Show Modest Movement, S&P 500 Futures Up 0.01%
select
2026-01-06
08:00:00
Oculis' Privosegtor Receives FDA Breakthrough Therapy Designation
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News

Newsfilter
8.5
03-05Newsfilter
Oculis Announces Upcoming Investor Conference Schedule
  • Breakthrough Therapy Progress: Oculis' Privosegtor has received breakthrough therapy designation for optic neuritis (ON), which is expected to drive its strategic transformation in neuro-ophthalmology and tap into a market opportunity exceeding $7 billion in the U.S.
  • Clinical Trial Advancements: The topline results for OCS-01 from the DIAMOND Phase 3 trials are anticipated in Q2 2026, positioning this non-invasive eye drop as a potential first registered treatment for diabetic macular edema (DME), thereby solidifying Oculis' leadership in ophthalmology.
  • Precision Medicine Development: Licaminlimab is being evaluated in a registrational trial as the first genotype-based program for dry eye disease (DED), aiming to enhance personalized treatment options and strengthen Oculis' competitive edge in the ophthalmic market.
  • Investor Conference Schedule: Oculis will present its innovative portfolio at several investor conferences in March, with CEO Riad Sherif scheduled to present on March 10, which is expected to attract investor interest in its robust clinical pipeline and financial health.
NASDAQ.COM
9.5
03-04NASDAQ.COM
Oculis Reports 2025 Financial Results and Clinical Milestones
  • Narrowed Q4 Loss: Oculis reported a net loss of 23.51 million Swiss Francs in Q4 2025, or 0.42 Franc per share, down from 28.66 million Francs or 0.67 Franc per share last year, indicating improved cost management efforts.
  • Expanded Annual Loss: The full-year net loss for 2025 increased to 98.96 million Francs, or 1.89 Franc per share, compared to 85.78 million Francs and 2.12 Franc per share in 2024, reflecting heightened R&D expenditures and intensified market competition.
  • Increased Cash Reserves: As of December 31, 2025, the company reported cash and short-term investments of $268.7 million, significantly up from $109.0 million last year, providing a cash runway into 2029 to support ongoing operations.
  • Clinical Trial Progress: The Phase 3 trials for OCS-01 are nearing completion with readouts expected in Q2 2026, and if positive, a New Drug Application to the FDA is planned for Q4 2026, with a potential market opportunity exceeding $30 billion.
seekingalpha
9.5
03-03seekingalpha
Oculis Holding Reports Q4 Earnings Beat Expectations
  • Earnings Beat: Oculis Holding reported a Q4 GAAP EPS of CHF -0.42, surpassing expectations by $0.11, indicating potential improvements in profitability and investor confidence.
  • Significant Revenue Growth: The operating income for Q4 reached CHF 411K, a substantial increase from CHF 3K in Q4 2024, reflecting strong market demand and sales performance.
  • FDA Breakthrough Therapy Status: The company received FDA breakthrough therapy designation for its optic neuritis treatment, which could expedite the product's market entry and provide new revenue growth opportunities.
  • Increased Investor Attention: Oculis's presentation at the 44th Annual J.P. Morgan Healthcare Conference garnered significant investor interest, further enhancing market confidence in its future prospects.
Newsfilter
5.0
02-17Newsfilter
Oculis Appoints New Chief Legal Officer to Enhance Leadership
  • Leadership Enhancement: Oculis has appointed Katie Kazem as Chief Legal Officer, leveraging her extensive experience in life sciences to advance the company's three late-stage assets toward clinical and regulatory milestones.
  • Legal Compliance Expertise: With over 15 years of experience in capital markets and corporate governance, Kazem has advised numerous public life sciences companies, which is expected to enhance Oculis's ability to navigate complex transactions and regulatory matters.
  • Accelerated Clinical Progress: Oculis's Privosegtor project is advancing in the PIONEER program, which is expected to support registration trials for a novel neuroprotective platform, further solidifying its market position in neuro-ophthalmology.
  • Deepening Strategic Collaboration: Kazem has served as external legal counsel since Oculis's NASDAQ listing in 2023, and will continue to work closely with the management team to drive rapid progress in clinical and commercialization efforts.
Globenewswire
3.5
01-08Globenewswire
Oculis Receives FDA Breakthrough Therapy Designation, Potential Market Exceeds $7 Billion
  • Breakthrough Therapy Designation: Oculis's Privosegtor has received FDA breakthrough therapy designation due to significant vision improvements in the ACUITY Phase 2 trial, positioning it as the first neuroprotective therapy for optic neuropathies, addressing a critical unmet medical need.
  • Substantial Market Potential: The PIONEER program aims to support registration for Privosegtor in optic neuritis and non-arteritic anterior ischemic optic neuropathy, representing a potential market opportunity exceeding $7 billion, highlighting the company's strategic focus in neuro-ophthalmology.
  • Clinical Trial Progress: Oculis's OCS-01 eye drops are currently in Phase 3 trials, with topline results from the DIAMOND trial expected in Q2 2026, and if approved, it will be the first non-invasive treatment for diabetic macular edema.
  • Future Outlook: CEO Riad Sherif stated that 2026 is set to be a milestone-rich year for Oculis, with advancements in both Privosegtor and OCS-01 expected to significantly transform the treatment landscape for neuro-axonal diseases.
Globenewswire
3.5
01-08Globenewswire
Oculis Receives FDA Breakthrough Therapy Designation, Potential Market Exceeds $7 Billion
  • Breakthrough Therapy Designation: Oculis's Privosegtor has received FDA breakthrough therapy designation based on significant vision improvement shown in the ACUITY Phase 2 trial, potentially becoming the first neuroprotective therapy for optic neuritis, addressing a substantial unmet medical need.
  • Significant Market Opportunity: The PIONEER program by Oculis includes three pivotal trials for optic neuritis and non-arteritic anterior ischemic optic neuropathy (NAION), with a projected market opportunity exceeding $7 billion in the U.S., showcasing the company's strategic positioning in neuro-ophthalmology.
  • Clinical Trial Progress: OCS-01 eye drops are currently in Phase 3 development targeting diabetic macular edema (DME), with topline results from the DIAMOND Phase 3 trials expected in Q2 2026, which could fill a significant market gap if approved.
  • Industry Conference Presentation: Oculis CEO Riad Sherif will present at the J.P. Morgan Healthcare Conference on January 14, 2026, highlighting the company's innovative potential and market prospects in the neuro-ophthalmology sector.
Wall Street analysts forecast OCS stock price to rise
6 Analyst Rating
Wall Street analysts forecast OCS stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
29.00
Averages
40.00
High
55.00
Current: 0.000
sliders
Low
29.00
Averages
40.00
High
55.00
Stifel
Buy
maintain
$40 -> $50
AI Analysis
2026-03-05
Reason
Stifel
Price Target
$40 -> $50
AI Analysis
2026-03-05
maintain
Buy
Reason
Stifel raised the firm's price target on Oculis to $50 from $40 and keeps a Buy rating on the shares after having hosted management on the road. The company approaches pivotal data on OCS-01's DIAMOND studies in DME, is rapidly advancing privosegtor, and continues the licaminlimab pivotal studies, the analyst noted.
H.C. Wainwright
Buy
maintain
$42 -> $44
2026-03-04
Reason
H.C. Wainwright
Price Target
$42 -> $44
2026-03-04
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on Oculis to $44 from $42 and keeps a Buy rating on the shares following the Q4 report. The firm believes OCS-01 has the potential to be the first topical eye drop approved to treat of diabetic macular edema. Oculis is on track to report topline data in Q2, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for OCS
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Valuation Metrics

The current forward P/E ratio for Oculis Holding AG (OCS.O) is -9.48, compared to its 5-year average forward P/E of -5.46. For a more detailed relative valuation and DCF analysis to assess Oculis Holding AG's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.46
Current PE
-9.48
Overvalued PE
-2.01
Undervalued PE
-8.91

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.58
Current EV/EBITDA
-7.86
Overvalued EV/EBITDA
-1.73
Undervalued EV/EBITDA
-9.44

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
570.16
Current PS
1733.49
Overvalued PS
1085.30
Undervalued PS
55.01

Financials

AI Analysis
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OCS
Oculis Holding AG
1.51B

Whales Holding OCS

F
Folketrygdfondet
Holding
OCS
+33.89%
3M Return
E
Eqt Fund Management S.à R.L.
Holding
OCS
-16.95%
3M Return

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Frequently Asked Questions

What is Oculis Holding AG (OCS) stock price today?

The current price of OCS is 27.28 USD — it has decreased -4.78

What is Oculis Holding AG (OCS)'s business?

Oculis Holding AG is a Switzerland-based company primally engaged in biotechnology sector. The Company is focused on the development of eye disease treatment for ophthalmology. It includes OCS-01, based on the OPTIREACH technology, a topical retinal candidate for diabetic macular edema (DME); OCS-02, a topical biologic candidate for dry eye disease (DED) in a form of a single chain antibody fragment; and OCS-05, a disease modifying candidate for acute optic neuritis (AON) and for other neuro-ophtha disorders such as glaucoma, diabetic retinopathy, geographic atrophy, and neurotrophic keratitis. The Company have operations in the USA, Europe and China. Ocullis deliver treatments to patients worldwide.

What is the price predicton of OCS Stock?

Wall Street analysts forecast OCS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OCS is40.00 USD with a low forecast of 29.00 USD and a high forecast of 55.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Oculis Holding AG (OCS)'s revenue for the last quarter?

Oculis Holding AG revenue for the last quarter amounts to -20.63M USD, increased 19.54

What is Oculis Holding AG (OCS)'s earnings per share (EPS) for the last quarter?

Oculis Holding AG. EPS for the last quarter amounts to -16343000.00 USD, increased 56.92

How many employees does Oculis Holding AG (OCS). have?

Oculis Holding AG (OCS) has 60 emplpoyees as of March 12 2026.

What is Oculis Holding AG (OCS) market cap?

Today OCS has the market capitalization of 1.58B USD.