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LXRX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.715
Open
1.691
VWAP
1.70
Vol
1.92M
Mkt Cap
728.73M
Low
1.665
Amount
3.27M
EV/EBITDA(TTM)
--
Total Shares
423.68M
EV
686.50M
EV/OCF(TTM)
--
P/S(TTM)
12.54
Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company focusing on the research and development of pilavapadin, LX9851 and sotagliflozin and the commercialization of INPEFA. It is developing pilavapadin (LX9211), an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. It has completed three Phase II clinical trials evaluating the safety and tolerability of pilavapadin and its effects on diabetic peripheral neuropathic pain (DPNP) and neuropathic pain. It is developing LX9851, an orally delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic disorders and is conducting preclinical development of LX9851 in preparation for filing an investigational new drug application. It is commercializing INPEFA (sotagliflozin), an orally delivered small molecule drug, in the United States to reduce the risk of cardiovascular death, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus.
Show More

Events Timeline

(ET)
2026-03-11
08:20:00
Lexicon Presents Sotagliflozin Clinical Data Analysis Results
select
2026-03-05 (ET)
2026-03-05
07:10:00
Lexicon Reports Q4 Revenue of $5.5M, Beating Consensus
select
2026-01-30 (ET)
2026-01-30
12:00:00
Major Averages Broadly Lower as Tech Stocks Decline
select
2026-01-30
06:10:00
Jefferies and Piper Sandler Jointly Manage Offering
select
2026-01-29 (ET)
2026-01-29
16:40:00
Lexicon Pharmaceuticals Commences Underwritten Public Offering
select
2026-01-21 (ET)
2026-01-21
16:20:00
Dow Jones Rises 588.64 Points as Trump Discusses Greenland
select
2026-01-21
12:10:00
Major Averages Bounce Back at Noon, Dow Up 288.53 Points
select
2026-01-21
08:40:00
Lexicon Completes FDA Phase 2 Meeting, Advances Drug Development
select

News

seekingalpha
9.5
03-05seekingalpha
Lexicon Pharmaceuticals Q4 2025 Earnings Call Insights
  • Core Program Progress: Lexicon Pharmaceuticals is advancing three late-stage programs in cardiometabolic disease and chronic pain, with significant progress in the development of sotagliflozin for hypertrophic cardiomyopathy, expected to submit an NDA in 2026, indicating a strategic focus on critical therapeutic areas.
  • Financial Position Improvement: Total revenues for Q4 2025 were $5.5 million, with full-year revenues reaching $49.8 million, showing significant improvement from 2024, while net loss decreased from $33.8 million in 2024 to $15.5 million, reflecting successful cost control and operational efficiency.
  • R&D Expense Optimization: R&D expenses for Q4 dropped to $11.3 million, halving compared to 2024, indicating Lexicon's more efficient resource allocation and continued focus on advancing core programs in the future.
  • Future Outlook: Management expects operating expenses in 2026 to range between $100 million and $110 million, with R&D expenses projected at $63 million to $68 million, demonstrating confidence in future growth while emphasizing the smooth progress of the SONATA-HCM trial and plans for NDA resubmission for Zynquista.
seekingalpha
9.5
03-05seekingalpha
Lexicon Pharmaceuticals Q4 Earnings Beat Expectations
  • Earnings Highlights: Lexicon Pharmaceuticals reported a Q4 GAAP EPS of -$0.04, beating expectations by $0.03, indicating potential improvements in profitability despite ongoing challenges.
  • Revenue Performance: The company generated $5.49 million in revenue, a 79.3% year-over-year decline, yet it exceeded expectations by $2.35 million, suggesting some resilience in market demand amid adversity.
  • Liquidity Position: As of December 31, 2025, Lexicon's total cash, investments, and restricted cash amounted to $125.2 million, down from $238.0 million in the same period of 2024, highlighting pressures on the company's financial management.
  • Market Reaction: Lexicon Pharmaceuticals showcased FDA feedback on Pilavapadin at the J.P. Morgan Healthcare Conference, and despite facing challenges, the market remains cautiously optimistic about its future prospects.
seekingalpha
9.5
03-04seekingalpha
Lexicon Pharmaceuticals to Announce Q4 Earnings on March 5
  • Earnings Announcement: Lexicon Pharmaceuticals is set to release its Q4 earnings on March 5 before market open, with a consensus EPS estimate of -$0.07, indicating ongoing challenges in profitability.
  • Revenue Decline: The anticipated revenue of $3.14 million for Q4 represents an 88.2% year-over-year decline, highlighting significant pressures in market competition and product sales that could impact future liquidity.
  • Positive FDA Feedback: Despite financial hurdles, Lexicon's Pilavapadin drug has received FDA feedback allowing it to proceed, providing potential growth opportunities for the company's product pipeline and possibly improving its market outlook.
  • Active Insider Trading: Lexicon's stock recently spiked following insider buying, reflecting management's confidence in the company's future, which may attract more investor interest in its stock performance.
Newsfilter
2.0
03-03Newsfilter
Chronic Kidney Disease Market Growth Drivers
  • Market Size Growth: According to analysis, the chronic kidney disease (CKD) market size was approximately $4.8 billion in 2024 and is expected to grow further by 2034, reflecting increased demand for new therapies and an expanding patient base.
  • Rising Patient Numbers: In 2024, there were about 82 million prevalent cases of CKD across the 7 major markets (7MM), with projections indicating continued growth from 2025 to 2034, primarily driven by an aging population and the rising prevalence of diabetes and hypertension.
  • Launch of New Therapies: The introduction of emerging therapies such as AstraZeneca's Zibotentan/Dapagliflozin and Boehringer Ingelheim's Vicadrostat + Empagliflozin is expected to significantly boost market growth and improve treatment outcomes for patients.
  • Advancements in Biomarkers: Progress in biomarkers like KIM-1 and NGAL enables more precise early detection of CKD, thereby enhancing the potential for timely interventions and improving overall patient prognosis.
seekingalpha
5.0
02-19seekingalpha
Lexicon Pharmaceuticals Chairman Buys Over $350K in Shares
  • Chairman Share Purchase: Lexicon Pharmaceuticals Chairman Raymond Debbane purchased approximately 268.5K shares at an average price of $1.31 each, totaling over $352.9K through three transactions, reflecting confidence in the company's future prospects.
  • Increased Ownership: Following this purchase, Debbane's direct ownership in Lexicon has risen to over 1.6 million shares, further solidifying his control over the company and potentially boosting investor confidence.
  • Stock Price Recovery Context: Lexicon's shares rose in late January after the company disclosed a successful meeting with the FDA regarding the late-stage development of its experimental therapy pilavapidin, creating a favorable market environment for Debbane's acquisition.
  • Market Outlook: With positive FDA feedback, Lexicon's potential in treating diabetic peripheral neuropathic pain (DPNP) is gaining attention, which may attract more investors and drive the company's stock price higher in the future.
Newsfilter
8.5
02-06Newsfilter
Lexicon Pharmaceuticals Closes 32 Million Share Public Offering
  • Public Offering Size: Lexicon Pharmaceuticals successfully closed a public offering of 32 million shares of common stock at a price of $1.30 per share, reflecting the company's strong capital market presence and investor confidence.
  • Preferred Stock Placement: The concurrent private placement included 22.4 million shares of common stock and 367,145 shares of Series B Convertible Preferred Stock priced at $65 per share, further strengthening the company's capital structure.
  • Additional Purchase Options: The underwriters were granted a 30-day option to purchase an additional 4.8 million shares of common stock, providing Lexicon with potential additional funding to support research and operations.
  • Planned Use of Proceeds: Lexicon intends to utilize the net proceeds from the offerings for drug research and development as well as general corporate purposes, indicating the company's commitment to future product development and strategic positioning.
Wall Street analysts forecast LXRX stock price to rise
3 Analyst Rating
Wall Street analysts forecast LXRX stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
2.10
Averages
4.03
High
6.00
Current: 0.000
sliders
Low
2.10
Averages
4.03
High
6.00
Citi
Yigal Nochomovitz
Buy
maintain
AI Analysis
2026-03-10
New
Reason
Citi
Yigal Nochomovitz
Price Target
AI Analysis
2026-03-10
New
maintain
Buy
Reason
Citi analyst Yigal Nochomovitz raised the firm's price target on Lexicon to $2.30 from $2.10 and keeps a Buy rating on the shares.
H.C. Wainwright
H.C. Wainwright
Buy
maintain
$4 -> $6
2026-03-05
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$4 -> $6
2026-03-05
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on Lexicon to $6 from $4 and keeps a Buy rating on the shares following the Q4 report. The firm increased its probability of success for pilavapadin to 30% from 15%. It expects an "important partnership" for the Phase 3-ready pilavapadin based on Lexicon's work on the clinical and regulatory front helping to de-risk program.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for LXRX
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Valuation Metrics

The current forward P/E ratio for Lexicon Pharmaceuticals Inc (LXRX.O) is -4.15, compared to its 5-year average forward P/E of -4.33. For a more detailed relative valuation and DCF analysis to assess Lexicon Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.33
Current PE
-4.15
Overvalued PE
-0.34
Undervalued PE
-8.33

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.78
Current EV/EBITDA
-3.82
Overvalued EV/EBITDA
1.78
Undervalued EV/EBITDA
-11.33

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
485.54
Current PS
20.42
Overvalued PS
1779.39
Undervalued PS
-808.31

Financials

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Whales Holding LXRX

A
Artal Group S.A.
Holding
LXRX
+7.65%
3M Return
S
Sessa Capital IM, L.P.
Holding
LXRX
-10.80%
3M Return

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Frequently Asked Questions

What is Lexicon Pharmaceuticals Inc (LXRX) stock price today?

The current price of LXRX is 1.72 USD — it has increased 0

What is Lexicon Pharmaceuticals Inc (LXRX)'s business?

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company focusing on the research and development of pilavapadin, LX9851 and sotagliflozin and the commercialization of INPEFA. It is developing pilavapadin (LX9211), an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. It has completed three Phase II clinical trials evaluating the safety and tolerability of pilavapadin and its effects on diabetic peripheral neuropathic pain (DPNP) and neuropathic pain. It is developing LX9851, an orally delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic disorders and is conducting preclinical development of LX9851 in preparation for filing an investigational new drug application. It is commercializing INPEFA (sotagliflozin), an orally delivered small molecule drug, in the United States to reduce the risk of cardiovascular death, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus.

What is the price predicton of LXRX Stock?

Wall Street analysts forecast LXRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LXRX is4.03 USD with a low forecast of 2.10 USD and a high forecast of 6.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Lexicon Pharmaceuticals Inc (LXRX)'s revenue for the last quarter?

Lexicon Pharmaceuticals Inc revenue for the last quarter amounts to 5.49M USD, decreased -79.31

What is Lexicon Pharmaceuticals Inc (LXRX)'s earnings per share (EPS) for the last quarter?

Lexicon Pharmaceuticals Inc. EPS for the last quarter amounts to -0.04 USD, decreased -55.56

How many employees does Lexicon Pharmaceuticals Inc (LXRX). have?

Lexicon Pharmaceuticals Inc (LXRX) has 81 emplpoyees as of March 12 2026.

What is Lexicon Pharmaceuticals Inc (LXRX) market cap?

Today LXRX has the market capitalization of 728.73M USD.