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LXRX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
2.430
Open
2.315
VWAP
2.38
Vol
553.92K
Mkt Cap
1.03B
Low
2.300
Amount
1.32M
EV/EBITDA(TTM)
--
Total Shares
444.20M
EV
767.42M
EV/OCF(TTM)
--
P/S(TTM)
10.70
Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders.
Show More

Events Timeline

(ET)
2026-05-07
09:20:00
Company Reports Q1 Revenue of $21.1M, Exceeds Expectations
select
2026-04-17 (ET)
2026-04-17
08:20:00
Lexicon Pharmaceuticals to Present Pilavapadin Study Results at AAN Meeting
select
2026-04-17
08:10:00
Company and Bank Show Strong Core Deposit Growth in Q1
select
2026-03-23 (ET)
2026-03-23
07:50:00
Lexicon and Novo Nordisk Initiate Phase 1 Study of LX9851
select
2026-03-11 (ET)
2026-03-11
08:20:00
Lexicon Presents Sotagliflozin Clinical Data Analysis Results
select
2026-03-05 (ET)
2026-03-05
07:10:00
Lexicon Reports Q4 Revenue of $5.5M, Beating Consensus
select
2026-01-30 (ET)
2026-01-30
12:00:00
Major Averages Broadly Lower as Tech Stocks Decline
select

News

seekingalpha
9.5
05-07seekingalpha
Lexicon Pharmaceuticals Reports Q1 2026 Revenue Surge and Reduced Losses
  • Revenue Surge: Lexicon Pharmaceuticals reported Q1 2026 revenue of $21.1 million, a staggering 1574.6% increase year-over-year, exceeding market expectations by $11.32 million, indicating strong performance in product promotion and market demand.
  • Significant Loss Reduction: The net loss for Q1 2026 was $1.0 million, or less than $0.01 per share, a substantial decrease from the $25.3 million loss, or $0.07 per share, in the same period of 2025, reflecting improved cost control and operational efficiency.
  • Improved Cash Position: As of March 31, 2026, Lexicon had $199.7 million in cash, investments, and restricted cash, up from $125.2 million as of December 31, 2025, driven by $96.5 million in net proceeds from stock sales in February 2026.
  • Strategic Investment Outlook: The strong financial performance in Q1 2026 provides robust funding support for Lexicon's ongoing R&D and market expansion, particularly with the SONATA-HCM project, which has surpassed 50% enrollment, laying a solid foundation for future growth.
seekingalpha
9.5
05-06seekingalpha
Lexicon Pharmaceuticals to Announce Q1 Earnings on May 7
  • Earnings Announcement Schedule: Lexicon Pharmaceuticals is set to announce its Q1 2025 earnings on May 7 before market open, with consensus EPS estimated at -$0.04 and revenue forecasted at $9.78 million, a significant increase from $1.26 million in Q1 2025, indicating potential for revenue growth.
  • Earnings Estimate Revisions: Over the past three months, Lexicon's EPS estimates have seen two upward revisions with no downward adjustments, reflecting analysts' growing confidence in the company's future profitability, while revenue estimates also experienced two upward revisions, indicating optimistic market demand for its products.
  • SONATA-HCM Progress: Lexicon highlighted that enrollment for SONATA-HCM has surpassed 50% as part of its 2026 milestones, which not only indicates smooth progress in clinical trials but also lays a foundation for future revenue growth, thereby boosting investor confidence.
  • Insider Trading Activity: Lexicon's stock price spiked following insider buying, demonstrating management's confidence in the company's future prospects, which may attract more investor interest in its stock performance.
stocktwits
8.5
03-23stocktwits
Novo Nordisk Advances Next-Gen Obesity Treatments with LX9851 Trial
  • Clinical Trial Initiation: Novo Nordisk has announced the initiation of a Phase 1 study for LX9851, an oral non-incretin drug candidate from Lexicon Pharmaceuticals aimed at treating obesity and related metabolic disorders, marking a significant advancement in the company's obesity treatment efforts.
  • Milestone Payment Triggered: The start of this trial triggers a second $10 million milestone payment to Lexicon under their licensing agreement signed in March 2025, granting Novo Nordisk exclusive global rights to develop and commercialize the drug, with Lexicon eligible for up to $1 billion in total milestone payments and royalties on future sales.
  • Trial Scale and Timeline: The Phase 1 study will evaluate safety and dosing in 96 overweight or obese participants, expected to be completed by early 2027, demonstrating Novo Nordisk's commitment and strategic planning in advancing its drug pipeline.
  • Market Reaction and Outlook: While NVO shares fell 1.5%, LXRX's stock rose about 1% in pre-market trading, reflecting market optimism regarding the new drug development and enhancing Novo Nordisk's competitive position in the obesity treatment market.
moomoo
9.0
03-23moomoo
Lexicon Pharmaceuticals and Novo Nordisk Launch Phase 1 Study for Oral Obesity Drug Candidate LX9851
  • Announcement of Phase 1 Study: Lexicon Pharmaceuticals and Novartis have announced the initiation of a Phase 1 study for the oral obesity drug candidate, LX9851.

  • Focus on Obesity Treatment: The study aims to evaluate the safety and efficacy of LX9851 as a potential treatment for obesity, highlighting the ongoing efforts in developing innovative therapies in this area.

seekingalpha
9.5
03-05seekingalpha
Lexicon Pharmaceuticals Q4 2025 Earnings Call Insights
  • Core Program Progress: Lexicon Pharmaceuticals is advancing three late-stage programs in cardiometabolic disease and chronic pain, with significant progress in the development of sotagliflozin for hypertrophic cardiomyopathy, expected to submit an NDA in 2026, indicating a strategic focus on critical therapeutic areas.
  • Financial Position Improvement: Total revenues for Q4 2025 were $5.5 million, with full-year revenues reaching $49.8 million, showing significant improvement from 2024, while net loss decreased from $33.8 million in 2024 to $15.5 million, reflecting successful cost control and operational efficiency.
  • R&D Expense Optimization: R&D expenses for Q4 dropped to $11.3 million, halving compared to 2024, indicating Lexicon's more efficient resource allocation and continued focus on advancing core programs in the future.
  • Future Outlook: Management expects operating expenses in 2026 to range between $100 million and $110 million, with R&D expenses projected at $63 million to $68 million, demonstrating confidence in future growth while emphasizing the smooth progress of the SONATA-HCM trial and plans for NDA resubmission for Zynquista.
seekingalpha
9.5
03-05seekingalpha
Lexicon Pharmaceuticals Q4 Earnings Beat Expectations
  • Earnings Highlights: Lexicon Pharmaceuticals reported a Q4 GAAP EPS of -$0.04, beating expectations by $0.03, indicating potential improvements in profitability despite ongoing challenges.
  • Revenue Performance: The company generated $5.49 million in revenue, a 79.3% year-over-year decline, yet it exceeded expectations by $2.35 million, suggesting some resilience in market demand amid adversity.
  • Liquidity Position: As of December 31, 2025, Lexicon's total cash, investments, and restricted cash amounted to $125.2 million, down from $238.0 million in the same period of 2024, highlighting pressures on the company's financial management.
  • Market Reaction: Lexicon Pharmaceuticals showcased FDA feedback on Pilavapadin at the J.P. Morgan Healthcare Conference, and despite facing challenges, the market remains cautiously optimistic about its future prospects.
Wall Street analysts forecast LXRX stock price to rise
3 Analyst Rating
Wall Street analysts forecast LXRX stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
2.10
Averages
4.03
High
6.00
Current: 0.000
sliders
Low
2.10
Averages
4.03
High
6.00
Citi
Buy
upgrade
AI Analysis
2026-05-11
New
Reason
Citi
Price Target
AI Analysis
2026-05-11
New
upgrade
Buy
Reason
Citi raised the firm's price target on Lexicon to $3.10 from $2.30 and keeps a Buy rating on the shares.
Citi
Yigal Nochomovitz
Buy
maintain
2026-03-10
Reason
Citi
Yigal Nochomovitz
Price Target
2026-03-10
maintain
Buy
Reason
Citi analyst Yigal Nochomovitz raised the firm's price target on Lexicon to $2.30 from $2.10 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for LXRX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Lexicon Pharmaceuticals Inc (LXRX.O) is 0.00, compared to its 5-year average forward P/E of -3.86. For a more detailed relative valuation and DCF analysis to assess Lexicon Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.86
Current PE
0.00
Overvalued PE
-0.80
Undervalued PE
-6.92

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.91
Current EV/EBITDA
-14.96
Overvalued EV/EBITDA
2.96
Undervalued EV/EBITDA
-14.79

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
437.24
Current PS
39.02
Overvalued PS
1680.97
Undervalued PS
-806.49

Financials

AI Analysis
Annual
Quarterly

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Whales Holding LXRX

A
Artal Group S.A.
Holding
LXRX
+16.80%
3M Return
S
Sessa Capital IM, L.P.
Holding
LXRX
+6.57%
3M Return

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Frequently Asked Questions

What is Lexicon Pharmaceuticals Inc (LXRX) stock price today?

The current price of LXRX is 2.395 USD — it has increased 3.68

What is Lexicon Pharmaceuticals Inc (LXRX)'s business?

Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders.

What is the price predicton of LXRX Stock?

Wall Street analysts forecast LXRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LXRX is4.03 USD with a low forecast of 2.10 USD and a high forecast of 6.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Lexicon Pharmaceuticals Inc (LXRX)'s revenue for the last quarter?

Lexicon Pharmaceuticals Inc revenue for the last quarter amounts to 21.10M USD, increased 1572.11

What is Lexicon Pharmaceuticals Inc (LXRX)'s earnings per share (EPS) for the last quarter?

Lexicon Pharmaceuticals Inc. EPS for the last quarter amounts to -0.00 USD, decreased -100.00

How many employees does Lexicon Pharmaceuticals Inc (LXRX). have?

Lexicon Pharmaceuticals Inc (LXRX) has 81 emplpoyees as of May 12 2026.

What is Lexicon Pharmaceuticals Inc (LXRX) market cap?

Today LXRX has the market capitalization of 1.03B USD.