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ANNX Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
6.200
Open
5.670
VWAP
5.98
Vol
2.22M
Mkt Cap
906.26M
Low
5.670
Amount
13.30M
EV/EBITDA(TTM)
--
Total Shares
149.06M
EV
619.29M
EV/OCF(TTM)
--
P/S(TTM)
--
Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.
Show More

Events Timeline

(ET)
2026-01-12
07:30:00
Annexon Outlines 2026 Strategic Priorities
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2026-01-08 (ET)
2026-01-08
08:10:00
Annexon Submits Marketing Authorization Application for tanruprubart to Treat GBS
select
2025-12-01 (ET)
2025-12-01
16:20:00
Clear Street Initiates Buy Rating on Annexon with $17 Price Target
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2025-11-17 (ET)
2025-11-17
09:29:08
BofA Reduces Annexon Price Target from $9 to $8
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2025-11-12 (ET)
2025-11-12
23:21:49
Annexon Prices 25.1M Share Spot Secondary Offering at $2.60
select
2025-11-12
16:15:55
Annexon reveals $75M offering of common stock and warrants
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2025-11-10 (ET)
2025-11-10
16:38:24
Annexon announces Q3 earnings per share of 37 cents, surpassing consensus estimate of 34 cents.
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News

Globenewswire
5.0
01-16Globenewswire
Annexon Grants 155,000 Stock Options to New Employees to Advance Immunotherapy
  • Employee Incentive Plan: Annexon has granted 155,000 stock options to two new non-executive employees under the 2022 Employment Inducement Award Plan, highlighting the company's commitment to attracting talent.
  • Option Details: The options have an exercise price of $6.16 per share, based on the closing price on January 15, 2026, with a ten-year term and a four-year vesting schedule, where 25% vests on the first anniversary of the grant.
  • Market Impact: This option grant not only enhances employee loyalty but may also improve the company's competitive position in the biopharmaceutical sector, particularly in the development of immunotherapies for neuroinflammatory diseases.
  • Strategic Significance: With a mission to provide therapies for nearly 10 million people suffering from neuroinflammatory diseases, this incentive measure will help attract and retain key talent, thereby advancing the company's objectives.
Benzinga
6.5
01-15Benzinga
Biotech Insider Buying Signals Strong, Three Companies Draw Attention
  • Insider Buying Signals: Summit Therapeutics has recently seen insider purchases, indicating management's confidence in its cancer drug's market potential, which could lead to significant stock price volatility in the future.
  • Neurological Drug Development: Annexon also reported insider buying, reflecting confidence in its antibody drugs targeting neurological diseases, despite the high clinical trial risks, the potential for success is substantial.
  • Cognitive Disorder Treatment: CervoMed's insider trading is noteworthy as its drug for Lewy body dementia shows market expectations for new therapies, although challenges in clinical trials remain significant.
  • Investor Strategy: Insider buying in biotech stocks is not a buy signal but a research prompt, urging investors to carefully assess company cash flow and market sentiment to avoid losses from market fluctuations.
seekingalpha
8.0
01-14seekingalpha
San Francisco Expands Free Childcare Access, Saving Families Thousands Annually
  • Income Support for Families: San Francisco's plan provides free childcare for children under five to families earning less than $230,000, while those earning up to $310,000 qualify for partial subsidies, potentially saving families tens of thousands of dollars annually.
  • Addressing Living Costs: The initiative targets childcare costs that can reach $30,000 annually for full-time infant care, with city officials stating that this move offers meaningful economic relief for middle-class families, helping them remain in the city.
  • Funding Assurance: Funding for the initiative will come from a commercial rent tax approved by voters in 2018, with estimates suggesting that unused revenue will support approximately 20,000 children through 2032, ensuring the program's sustainability.
  • Political Context: Mayor Daniel Lurie, as part of a growing group of Democratic leaders, is pushing this affordability agenda, reflecting a broader focus on the economic pressures facing middle-class families post-2024 election cycle, with similar efforts underway in New York.
Globenewswire
5.0
2025-12-17Globenewswire
Annexon Grants 19,000 Stock Options to New Employee at $4.91 Exercise Price
  • Employee Incentive Program: Annexon has granted 19,000 stock options to a new non-executive employee under the 2022 Employment Inducement Award Plan, with an exercise price of $4.91 per share, highlighting the company's commitment to attracting and retaining talent.
  • Long-Term Incentive Mechanism: The options have a ten-year term and vest over four years, with 25% vesting on the first anniversary and the remainder vesting monthly, aimed at promoting employee retention and contribution through sustained incentives.
  • Market Reaction Potential: The options are priced based on the closing price on December 15, 2025, reflecting the company's confidence in future stock price appreciation, which could positively influence investor sentiment.
  • Strategic Development Focus: Annexon is dedicated to developing complement inhibitors targeting neuroinflammation to address the unmet medical needs of nearly 10 million patients worldwide, indicating a long-term strategic positioning in the biopharmaceutical sector.
Newsfilter
5.0
2025-12-17Newsfilter
Annexon Grants 19,000 Stock Options to New Employee at $4.91 Exercise Price
  • Employee Incentive Program: Annexon has granted 19,000 stock options to a new non-executive employee under the 2022 Employment Inducement Award Plan, with an exercise price of $4.91 per share, reflecting the company's commitment to attracting and retaining talent.
  • Long-Term Incentive Structure: The options have a ten-year term and vest over four years, with 25% vesting on the first anniversary and the remainder vesting monthly, designed to enhance employee retention and motivation through a long-term incentive mechanism.
  • Compliance Assurance: This grant complies with Nasdaq Listing Rule 5635(c)(4), ensuring the company's adherence to regulations while strengthening its position in attracting and retaining key talent in the competitive biopharmaceutical sector.
  • Strategic Development Focus: Annexon is focused on developing complement inhibitors targeting neuroinflammation to address unmet medical needs for nearly 10 million people globally, and this incentive measure will help attract more professionals to advance its research and development efforts.
Yahoo Finance
5.0
2025-11-20Yahoo Finance
Annexon Stock Soars Following Director's $5.06 Million Share Acquisition
  • Stock Performance: Annexon (ANNX) stock experienced an 8.6% increase in trading on Thursday.
  • Director Purchase: The rise in stock price followed the purchase of $5.06 million worth of shares by director Muneer Satter.
Wall Street analysts forecast ANNX stock price to rise
6 Analyst Rating
Wall Street analysts forecast ANNX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
16.40
High
27.00
Current: 0.000
sliders
Low
8.00
Averages
16.40
High
27.00
Chardan
Daniil Gataulin
Buy
initiated
$16
AI Analysis
2025-12-23
Reason
Chardan
Daniil Gataulin
Price Target
$16
AI Analysis
2025-12-23
initiated
Buy
Reason
Chardan analyst Daniil Gataulin initiated coverage of Annexon with a Buy rating and $16 price target. The firm cites the commercial potential of the company's complement C1q inhibitors tanruprubart in Guillain-Barre syndrome and vonaprument in geographic atrophy for the Buy rating. It sees additional upside potential from tanruprubart in Huntington's disease.
Wells Fargo
NULL
to
Overweight
upgrade
$14 -> $27
2025-11-19
Reason
Wells Fargo
Price Target
$14 -> $27
2025-11-19
upgrade
NULL
to
Overweight
Reason
Wells Fargo raised the firm's price target on Annexon to $27 from $14 and keeps an Overweight rating on the shares. The firm is raising its probability of success to 55% from 10% that vonaprument's Phase 3 trial in GA will be positive in the second half of 2026. Wells believes the setup offers a significant, asymmetric risk/reward skew with the potential for VC-like upside in the next 12 months.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ANNX
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Valuation Metrics

The current forward P/E ratio for Annexon Inc (ANNX.O) is -3.60, compared to its 5-year average forward P/E of -3.44. For a more detailed relative valuation and DCF analysis to assess Annexon Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.44
Current PE
-3.60
Overvalued PE
-1.23
Undervalued PE
-5.65

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.13
Current EV/EBITDA
-2.31
Overvalued EV/EBITDA
0.31
Undervalued EV/EBITDA
-2.58

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.05
Current PS
0.00
Overvalued PS
1.93
Undervalued PS
-1.82

Financials

AI Analysis
Annual
Quarterly

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Whales Holding ANNX

B
BVF Partners L.P.
Holding
ANNX
+6.57%
3M Return
B
Bellevue Asset Management AG
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ANNX
-2.17%
3M Return

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Frequently Asked Questions

What is Annexon Inc (ANNX) stock price today?

The current price of ANNX is 6.08 USD — it has increased 8.77

What is Annexon Inc (ANNX)'s business?

Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.

What is the price predicton of ANNX Stock?

Wall Street analysts forecast ANNX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ANNX is16.40 USD with a low forecast of 8.00 USD and a high forecast of 27.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Annexon Inc (ANNX)'s revenue for the last quarter?

Annexon Inc revenue for the last quarter amounts to -57.02M USD, increased 44.56

What is Annexon Inc (ANNX)'s earnings per share (EPS) for the last quarter?

Annexon Inc. EPS for the last quarter amounts to -52352000.00 USD, increased 63.48

How many employees does Annexon Inc (ANNX). have?

Annexon Inc (ANNX) has 100 emplpoyees as of March 11 2026.

What is Annexon Inc (ANNX) market cap?

Today ANNX has the market capitalization of 906.26M USD.