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ANNX Overview

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$
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0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
5.480
Open
5.370
VWAP
5.38
Vol
2.18M
Mkt Cap
888.03M
Low
5.235
Amount
11.71M
EV/EBITDA(TTM)
--
Total Shares
163.84M
EV
654.81M
EV/OCF(TTM)
--
P/S(TTM)
--
Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.
Show More

Events Timeline

(ET)
2026-05-07
16:10:00
Annexon Anticipates Key Data from ARCHER II Trial
select
2026-03-31 (ET)
2026-03-31
13:10:00
Biogen to Acquire Apellis Pharmaceuticals for $41 per Share
select
2026-03-30 (ET)
2026-03-30
16:20:00
Annexon Launches New Immunotherapies to Improve Neuroinflammation Treatment
select
2026-01-12 (ET)
2026-01-12
07:30:00
Annexon Outlines 2026 Strategic Priorities
select
2026-01-08 (ET)
2026-01-08
08:10:00
Annexon Submits Marketing Authorization Application for tanruprubart to Treat GBS
select
2025-12-01 (ET)
2025-12-01
16:20:00
Clear Street Initiates Buy Rating on Annexon with $17 Price Target
select

News

Newsfilter
2.0
05-11Newsfilter
GBS|CIDP Awareness Month: Celebrating 110 Years of Advocacy
  • Historical Milestone: This year marks the 110th anniversary of the discovery of Guillain-Barré syndrome (GBS), highlighting that despite over a century of research, thousands still face the challenges posed by this condition each year, indicating a continued need for awareness and research.
  • Story Sharing Initiative: The GBS|CIDP Foundation International has launched the 'GBS: 110 Years, 110 Stories' campaign, aiming to share 110 stories from GBS patients worldwide through short videos to raise public awareness and understanding of this rare disease.
  • Partnership for Awareness: The GBS|CIDP Foundation International has partnered with Annexon Biosciences to promote the GBS 110 campaign, with the goal of gathering and showcasing 110 patient stories to emphasize the urgent need for advancements in patient care.
  • Impact Statistics: According to the GBS|CIDP Foundation International, GBS affects approximately 2 in 100,000 people annually, while the prevalence of CIDP is estimated to be as high as 9 in 100,000, underscoring the rarity of these conditions and their profound impact on patients' lives.
Yahoo Finance
2.0
05-11Yahoo Finance
GBS|CIDP Awareness Month: 110 Years of Progress and Future Goals
  • Historical Milestone: This year marks the 110th anniversary of the discovery of Guillain-Barré syndrome (GBS), highlighting over a century of global research and awareness efforts since its identification by French neurologists in 1916, despite ongoing challenges faced by thousands of patients.
  • Story Sharing Initiative: The GBS|CIDP Foundation International has launched the 'GBS: 110 Years, 110 Stories' campaign to raise awareness of GBS and CIDP by collecting 110 patient stories from around the world, encouraging individuals to share their experiences to build a stronger support network.
  • Partnership for Awareness: The campaign collaborates with Annexon Biosciences to emphasize the urgent need for improved care for GBS patients through storytelling, with Annexon's VP noting the inspiring resilience of GBS survivors despite long-term impacts of the disease.
  • Disease Prevalence: GBS affects approximately 2 in 100,000 people annually, while the prevalence of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is estimated at 9 in 100,000, underscoring the necessity for continued focus and research on these rare conditions.
seekingalpha
9.5
05-07seekingalpha
Annexon Biosciences Q1 Earnings Beat Expectations
  • Earnings Performance: Annexon Biosciences reported a Q1 GAAP EPS of -$0.23, beating expectations by $0.06, indicating improvements in financial management and operational efficiency.
  • Strong Balance Sheet: As of March 31, 2026, the company holds approximately $225 million in cash, cash equivalents, and short-term investments, providing a financial runway into the second half of 2027, which enhances investor confidence in its sustainability.
  • C1q Inhibition Research Progress: Annexon is advancing research on C1q inhibition for vision preservation in geographic atrophy, leveraging key insights from the ARCHER trials, showcasing its innovative potential in ophthalmic treatments.
  • Historical Financial Data Review: Historical earnings data indicates that despite challenges, Annexon Biosciences is gradually improving its financial performance, reflecting its adaptability and growth potential in the biopharmaceutical industry.
NASDAQ.COM
5.0
04-15NASDAQ.COM
Annexon and Exzeo Executives Increase Stock Holdings
  • Carson's ANNX Purchase: William H. Carson bought 8,000 shares of ANNX at $6.20 each on Friday, totaling $49,600, which brings his total investment over the past year to $138,729 at an average cost of $3.77 per share, indicating strong confidence in the company's future.
  • ANNX Stock Surge: Following Carson's purchase, ANNX shares rose approximately 6% on Wednesday, reflecting positive market sentiment towards insider buying, which may further bolster investor confidence in the company's prospects.
  • Patel's XZO Investment: Exzeo Group CEO Paresh Patel purchased 2,000 shares of XZO at $15.13 each on Monday for a total of $30,260, increasing his total investment over the past year to $1.41 million at an average price of $19.02 per share, demonstrating optimism about the company's long-term value.
  • XZO Stock Performance: Patel's recent purchase has led to a 1.3% increase in XZO's stock price on Wednesday, with his investment currently yielding an approximate 8.8% gain based on the day's high of $16.45, indicating growing market confidence in Exzeo.
seekingalpha
9.5
03-30seekingalpha
Annexon Biosciences Q4 Earnings Beat Expectations
  • Earnings Highlights: Annexon Biosciences reported a Q4 GAAP EPS of -$0.28, beating expectations by $0.04, indicating improvements in financial management despite ongoing losses.
  • Cash Position: As of December 31, 2025, the company held $238.3 million in cash, cash equivalents, and short-term investments, including $86.3 million from a November 2025 public offering, ensuring operational funding for the coming years.
  • Investment Strategy: Annexon plans to focus investments on its lead late-stage programs, expecting to fund operations and anticipated milestones into the second half of 2027, reflecting confidence in future growth.
  • Market Outlook: The company is viewed as a high-risk, high-reward investment opportunity in a new approach to complement-mediated diseases, particularly in vision preservation for geographic atrophy, which may attract increased investor interest in its R&D progress.
moomoo
7.0
03-30moomoo
ANNEXON INC: EXPECTED CASH RESOURCES TO LAST THROUGH THE SECOND HALF OF 2027
  • Anticipated Cash Runway: The company expects a cash runway extending into the second half of 2027.
  • Financial Outlook: This projection indicates a stable financial position and potential for continued operations without immediate funding needs.
Wall Street analysts forecast ANNX stock price to rise
6 Analyst Rating
Wall Street analysts forecast ANNX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
16.40
High
27.00
Current: 0.000
sliders
Low
8.00
Averages
16.40
High
27.00
Goldman Sachs
Neutral
initiated
$7
AI Analysis
2026-05-12
Reason
Goldman Sachs
Price Target
$7
AI Analysis
2026-05-12
initiated
Neutral
Reason
Goldman Sachs initiated coverage of Annexon with a Neutral rating and $7 price target. Annexon is a clinical-stage biotechnology company developing therapeutics for neuroinflammatory diseases via inhibition of the complement pathway, the analyst tells investors in a research note. Goldman views the company's Phase data for vonaprument in geographic atrophy in Q4 as a "binary event."
Chardan
Daniil Gataulin
Buy
initiated
$16
2025-12-23
Reason
Chardan
Daniil Gataulin
Price Target
$16
2025-12-23
initiated
Buy
Reason
Chardan analyst Daniil Gataulin initiated coverage of Annexon with a Buy rating and $16 price target. The firm cites the commercial potential of the company's complement C1q inhibitors tanruprubart in Guillain-Barre syndrome and vonaprument in geographic atrophy for the Buy rating. It sees additional upside potential from tanruprubart in Huntington's disease.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ANNX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Annexon Inc (ANNX.O) is 0.00, compared to its 5-year average forward P/E of -3.20. For a more detailed relative valuation and DCF analysis to assess Annexon Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.20
Current PE
0.00
Overvalued PE
-1.24
Undervalued PE
-5.16

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.96
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.26
Undervalued EV/EBITDA
-2.17

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
18.39
Current PS
21.46
Overvalued PS
95.92
Undervalued PS
-59.15

Financials

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Annual
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Whales Holding ANNX

R
Redmile Group, LLC
Holding
ANNX
+7.59%
3M Return
B
BVF Partners L.P.
Holding
ANNX
+3.71%
3M Return
B
Bellevue Asset Management AG
Holding
ANNX
+1.82%
3M Return
L
Longaeva Partners L.P.
Holding
ANNX
+1.76%
3M Return

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Frequently Asked Questions

What is Annexon Inc (ANNX) stock price today?

The current price of ANNX is 5.42 USD — it has increased 0.93

What is Annexon Inc (ANNX)'s business?

Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.

What is the price predicton of ANNX Stock?

Wall Street analysts forecast ANNX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ANNX is16.40 USD with a low forecast of 8.00 USD and a high forecast of 27.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Annexon Inc (ANNX)'s revenue for the last quarter?

Annexon Inc revenue for the last quarter amounts to -46.05M USD, decreased -19.78

What is Annexon Inc (ANNX)'s earnings per share (EPS) for the last quarter?

Annexon Inc. EPS for the last quarter amounts to -46796000.00 USD, decreased -6.65

How many employees does Annexon Inc (ANNX). have?

Annexon Inc (ANNX) has 96 emplpoyees as of May 30 2026.

What is Annexon Inc (ANNX) market cap?

Today ANNX has the market capitalization of 888.03M USD.