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CNTX Overview

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ET
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ET
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Intellectia

Loading chart...

High
0.637
Open
0.620
VWAP
0.62
Vol
3.14M
Mkt Cap
58.06M
Low
0.589
Amount
1.95M
EV/EBITDA(TTM)
--
Total Shares
91.88M
EV
598.91K
EV/OCF(TTM)
--
P/S(TTM)
--
Context Therapeutics Inc. is a clinical-stage biopharmaceutical company, which is engaged in advancing T cell engaging (TCE) bispecific antibodies (bsAb) for solid tumors. It is building a portfolio of TCE bispecific therapeutics, including CTIM-76, a Claudin 6 (CLDN6) x CD3 TCE, CT-95, a Mesothelin (MSLN) x CD3 TCE, and CT-202, a Nectin cell adhesion protein 4 (Nectin-4) x CD3 TCE. CLDN6 is a tight junction membrane protein target expressed in multiple solid tumors and absent from or expressed at low levels in healthy adult tissues. CT-95 is intended to redirect T-cell-mediated lysis toward malignant cells expressing MSLN. MSLN is a membrane protein overexpressed in approximately 30% of cancers. Nectin-4 is a target for cancer therapy using a traditional antibody-drug conjugate, but it is also associated with certain adverse events, including neuropathy and rash. CT-202 is a pH-dependent TCE that is designed to be preferentially active within the acidic tumor microenvironment.
Show More

Events Timeline

(ET)
2026-06-15
07:00:00
Context Therapeutics Announces Positive Interim Data for CTIM-76
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2026-05-18 (ET)
2026-05-18
06:50:00
Context Therapeutics Amends License Agreement with BioAtla
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2026-05-06 (ET)
2026-05-06
17:00:00
Context Therapeutics Cash and Cash Equivalents Drop to $54.5M
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2026-04-02 (ET)
2026-04-02
08:00:00
Context Therapeutics' CTIM-76 Receives FDA Fast Track Designation
select
2025-11-07 (ET)
2025-11-07
07:33:38
Context Therapeutics Showcases CT-95 and CT-202 Initiatives at SITC Conference
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News

stocktwits
9.0
06-15stocktwits
CTIM-76 Early Data Triggers Stock Plunge
  • Clinical Data Response: Context Therapeutics reported that initial data from CTIM-76 indicated a 29% confirmed response rate among ovarian cancer patients in a cohort of 21 CLDN6-positive tumor patients, showcasing competitive activity despite a modest overall response rate after a median of seven prior therapies.
  • Severe Market Reaction: The company's stock plummeted 51% on Monday, marking its worst day ever, yet analysts view the selloff as a buying opportunity, maintaining optimism for future data improvements and potential recovery in stock performance.
  • Analyst Insights: H.C. Wainwright analyst Emily Bodnar maintains a 'Buy' rating with a $5 price target, highlighting CTIM-76's competitive activity in a challenging patient population, particularly among those previously treated with antibody-drug conjugates.
  • Future Catalysts: Context Therapeutics plans to release initial clinical data for CT-95 in September 2026 and expects to begin dosing the first patient in an early-stage study of CT-202 in the third quarter, indicating ongoing commitment to its research and development pipeline.
NASDAQ.COM
9.0
06-15NASDAQ.COM
CTIM-76 Shows Promising Interim Results in Ovarian Cancer Trial
  • Clinical Trial Progress: Context Therapeutics Inc. reported early signs of anti-tumor activity in its ongoing Phase 1 trial of CTIM-76 for heavily pretreated ovarian cancer patients, with 29% of evaluable patients (2 out of 7) achieving confirmed partial responses and 57% (4 out of 7) achieving disease control, indicating the drug's potential in treating this challenging condition.
  • Patient Background: As of the May 29, 2026 data cutoff, participants had a median of seven prior therapies, highlighting the urgent need for new treatment options in a population that has limited choices after multiple treatment failures.
  • Safety Assessment: Cytokine Release Syndrome (CRS) occurred in only 11% of ovarian cancer patients treated with CTIM-76, all at Grade 1 severity, suggesting a manageable safety profile at active doses, which enhances the drug's clinical applicability.
  • Future Development Plans: The company plans to transition CTIM-76 to a once-every-three-weeks dosing schedule in the second half of 2026 and expects to initiate a Phase 1b expansion study in 2027, with FDA Fast Track Designation reflecting the significant need for new treatment options.
Newsfilter
9.0
06-15Newsfilter
Context Therapeutics Reports Positive Interim Data for CTIM-76 in Ovarian Cancer
  • Clinical Trial Results: Context Therapeutics' CTIM-76 demonstrated a 29% overall response rate in platinum-resistant ovarian cancer patients who had undergone a median of seven prior therapies, indicating significant anti-tumor activity and potential as a new treatment option for these patients.
  • Safety Analysis: In the clinical trial of CTIM-76, Cytokine Release Syndrome (CRS) occurred in only 11% of patients, all at Grade 1, showcasing the drug's favorable tolerability and supporting future outpatient dosing strategies.
  • Pharmacokinetic Support: The pharmacokinetic profile of CTIM-76 indicates dose-dependent increases in exposure, which supports the exploration of a Q3W dosing schedule in the second half of 2026, potentially optimizing treatment regimens and enhancing patient compliance.
  • Future Development Plans: The company plans to conduct a Phase 1b clinical trial expansion for CTIM-76 in 2027, building on the current positive clinical data to further evaluate its efficacy and safety in platinum-resistant ovarian cancer patients.
Newsfilter
5.0
06-09Newsfilter
Context Therapeutics Grants Stock Options to New Employee
  • Stock Option Grant: Context Therapeutics awarded 146,000 stock options to a new employee on June 8, 2026, with an exercise price of $1.71 per share, aimed at attracting talent and enhancing employee loyalty.
  • Incentive Plan Details: The stock options were granted outside of the 2021 Long-Term Performance Incentive Plan, in accordance with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's flexibility and innovation in talent acquisition.
  • Vesting Arrangement: The stock options have a four-year vesting period, with one-fourth vesting on the first anniversary and the remainder vesting in monthly installments, ensuring continued employee contribution during their service.
  • Strategic Company Goals: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, and the stock option grant aids in attracting and retaining key talent to advance its innovative drug portfolio.
Newsfilter
5.0
05-27Newsfilter
Context Therapeutics Grants Stock Options to New Employee
  • Conference Presentation: Context Therapeutics is scheduled to present at the Jefferies Global Healthcare Conference in New York on June 3, 2026, which is expected to attract investor and industry attention, thereby enhancing the company's visibility in the biopharmaceutical sector.
  • Stock Option Grant: The company has granted a non-qualified stock option award for 146,000 shares to a new employee under Nasdaq Listing Rule 5635(c)(4), with an exercise price of $2.63 per share, aimed at attracting and retaining talent to strengthen the team for future R&D efforts.
  • Option Details: These stock options have a 10-year term and vest over four years, with 25% vesting on the first anniversary and the remainder vesting in equal monthly installments, ensuring continued employee contribution during their tenure with the company.
  • Strategic Goals: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, aiming to build an innovative therapeutic portfolio that enhances the company's competitiveness in the rapidly evolving biopharmaceutical market.
seekingalpha
9.5
05-07seekingalpha
Context Therapeutics Reports Q1 Financials with Cash Position Update
  • Cash Position: As of March 31, 2026, Context Therapeutics reported cash and cash equivalents of $54.5 million, down from $66.0 million at December 31, 2025, with expectations that this will fund operations into mid-2027, ensuring financial stability for the upcoming year.
  • R&D Expense Increase: The company incurred $7.0 million in research and development expenses in Q1 2026, a 100% increase from $3.5 million in Q1 2025, indicating a strong commitment to accelerating product development to meet market demands.
  • Slight Rise in G&A Costs: General and administrative expenses rose to $2.3 million in Q1 2026 from $2.1 million in Q1 2025, reflecting ongoing investments in operational management, which, while modest, underscore the company's focus on governance.
  • Decline in Other Income: Other income decreased to $0.7 million in Q1 2026 from $1.0 million in Q1 2025, primarily due to lower interest income from cash and cash equivalents, which may exert some pressure on the company's overall profitability.
Wall Street analysts forecast CNTX stock price to rise
5 Analyst Rating
Wall Street analysts forecast CNTX stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
4.00
Averages
5.25
High
7.00
Current: 0.000
sliders
Low
4.00
Averages
5.25
High
7.00
Maxim
Jason McCarthy
Buy
downgrade
$8 -> $4
AI Analysis
2026-06-16
New
Reason
Maxim
Jason McCarthy
Price Target
$8 -> $4
AI Analysis
2026-06-16
New
downgrade
Buy
Reason
Maxim analyst Jason McCarthy lowered the firm's price target on Context Therapeutics to $4 from $8 but keeps a Buy rating on the shares. The firm cites the company reporting of interim Phase 1a data for CTIM-76 in platinum-resistant ovarian cancer, but also believes the sharp negative stock price response is an "overreaction", the analyst tells investors in a research note. While this is a Phase 1a/b study, it is exploratory in the sense of learning about the drug, PK profile, dosing, safety/tolerability and initial efficacy, the firm added.
JonesResearch
Buy
maintain
$7
2026-06-15
New
Reason
JonesResearch
Price Target
$7
2026-06-15
New
maintain
Buy
Reason
JonesResearch views today's selloff in shares of Context Therapeutics (CNTX) as a buying opportunity. Context's Phase I study update of CTIM-76 in CLDN6+ solid tumors is "encouraging," says the firm, which expects the data to continue improving in future updates. Jones views the selloff as an overreaction, noting the 29% overall response rate was in platinum-resistant ovarian cancer patients with a median seven prior therapies. The firm points out that the median line of therapy with Zymeworks' (ZYME) ZW191 was three compared to CTIM-76's seven, with a range between 5-16 therapies, underscoring that CTIM-76 was tested in highly pre-treated patients. Jones does not see Context's and Zymeworks' trials as comparable given the difference in lines of therapy and patient characteristics. It keeps a Buy rating on Context Therapeutics with a $7 price target. The stock in afternoon trading is down 47%, or 65c, to 74c.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CNTX
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Valuation Metrics

The current forward P/E ratio for Context Therapeutics Inc (CNTX.O) is 0.00, compared to its 5-year average forward P/E of -2.74. For a more detailed relative valuation and DCF analysis to assess Context Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.74
Current PE
0.00
Overvalued PE
-0.47
Undervalued PE
-5.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.17
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.26
Undervalued EV/EBITDA
-1.59

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
-0.54
Current PS
0.00
Overvalued PS
2.83
Undervalued PS
-3.92

Financials

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Whales Holding CNTX

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Frequently Asked Questions

What is Context Therapeutics Inc (CNTX) stock price today?

The current price of CNTX is 0.6319 USD — it has increased 5.33

What is Context Therapeutics Inc (CNTX)'s business?

Context Therapeutics Inc. is a clinical-stage biopharmaceutical company, which is engaged in advancing T cell engaging (TCE) bispecific antibodies (bsAb) for solid tumors. It is building a portfolio of TCE bispecific therapeutics, including CTIM-76, a Claudin 6 (CLDN6) x CD3 TCE, CT-95, a Mesothelin (MSLN) x CD3 TCE, and CT-202, a Nectin cell adhesion protein 4 (Nectin-4) x CD3 TCE. CLDN6 is a tight junction membrane protein target expressed in multiple solid tumors and absent from or expressed at low levels in healthy adult tissues. CT-95 is intended to redirect T-cell-mediated lysis toward malignant cells expressing MSLN. MSLN is a membrane protein overexpressed in approximately 30% of cancers. Nectin-4 is a target for cancer therapy using a traditional antibody-drug conjugate, but it is also associated with certain adverse events, including neuropathy and rash. CT-202 is a pH-dependent TCE that is designed to be preferentially active within the acidic tumor microenvironment.

What is the price predicton of CNTX Stock?

Wall Street analysts forecast CNTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CNTX is5.25 USD with a low forecast of 4.00 USD and a high forecast of 7.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Context Therapeutics Inc (CNTX)'s revenue for the last quarter?

Context Therapeutics Inc revenue for the last quarter amounts to -9.34M USD, increased 68.99

What is Context Therapeutics Inc (CNTX)'s earnings per share (EPS) for the last quarter?

Context Therapeutics Inc. EPS for the last quarter amounts to -11466632.00 USD, increased 126.51

How many employees does Context Therapeutics Inc (CNTX). have?

Context Therapeutics Inc (CNTX) has 15 emplpoyees as of June 19 2026.

What is Context Therapeutics Inc (CNTX) market cap?

Today CNTX has the market capitalization of 58.06M USD.