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PLX Overview

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ET
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Intellectia

Loading chart...

High
2.160
Open
2.140
VWAP
2.13
Vol
734.79K
Mkt Cap
172.42M
Low
2.100
Amount
1.57M
EV/EBITDA(TTM)
12.09
Total Shares
80.57M
EV
118.12M
EV/OCF(TTM)
7.83
P/S(TTM)
2.47
Protalix BioTherapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of recombinant therapeutic proteins expressed through its proprietary plant cell-based expression system, ProCellEx. In addition, the Company is developing PEGylated uricase, or PRX-115, for the treatment of uncontrolled gout, Long Acting (LA) DNase I, or PRX-119, for the treatment of NETs-related diseases, and other technologies and preclinical assets. Its ProCellEx platform is being used to manufacture both of its approved and marketed products as well as PRX-115 and PRX-119. PRX-115, a plant cell-expressed recombinant PEGylated Uricase (urate oxidase) - a chemically modified enzyme to treat uncontrolled gout. PRX-119 is a plant cell-expressed PEGylated recombinant human DNase I product candidate. Its product includes Elelyso and Elfabrio. Elelyso is an enzyme replacement therapy (ERT) for the treatment of patients with Gaucher disease.
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Events Timeline

(ET)
2026-01-30
10:00:00
Chiesi and Protalix Update on Elfabrio Progress
select
2025-12-17 (ET)
2025-12-17
07:00:00
Protalix and Secarna Collaborate on Rare Renal Disease Therapies
select
2025-11-13 (ET)
2025-11-13
06:54:47
Protalix Announces Q3 Earnings Per Share of 3 Cents, Below Consensus Estimate of 5 Cents
select
2025-10-17 (ET)
2025-10-17
07:05:41
Protalix and Chiesi Global Receive Negative CHMP Opinion for Elfabrio
select
2025-07-21 (ET)
2025-07-21
06:52:09
Protalix appoints Gilad Mamlok as CFO
select
2025-06-30 (ET)
2025-06-30
07:00:54
Protalix added to Russell 3000, Russell 2000 Indexes
select

News

seekingalpha
9.5
05-13seekingalpha
Protalix BioTherapeutics Q1 2026 Earnings Call Insights
  • Milestone Revenue: Protalix received a $25 million milestone payment from Chiesi in Q1 2026, driving total revenue to $33.8 million, indicating positive progress in product promotion and expected to enhance future cash flow and market confidence.
  • Financial Outlook: The company reaffirmed its 2026 total revenue guidance of $78 million to $83 million, with Elfabrio revenues anticipated at $33 million to $35 million and Elelyso revenues at $20 million to $23 million, reflecting management's confidence in future performance.
  • Increased R&D Spending: R&D expenses rose to $5.4 million in Q1, up from $3.5 million in the prior year, primarily for preparations for the Phase II RELEASE study of PRX-115, demonstrating the company's ongoing investment in new product development.
  • Net Income Turnaround: The quarter saw a net income of $18.3 million, or $0.23 per share, compared to a net loss of $3.6 million in the same period last year, showcasing a significant improvement in the company's financial health and boosting investor confidence in its long-term growth potential.
seekingalpha
9.5
05-13seekingalpha
Protalix BioTherapeutics Reaffirms 2026 Revenue Guidance
  • Earnings Highlights: Protalix BioTherapeutics reported a Q1 GAAP EPS of $0.22 with revenues of $33.75 million, reflecting a remarkable 233.8% year-over-year growth, indicating strong market momentum for the company.
  • 2026 Revenue Outlook: The company reaffirms its 2026 revenue expectations, projecting total revenues to range from $78 million to $83 million, including a $25 million milestone already received, showcasing confidence in future performance.
  • Sales Forecast: For 2026, Protalix anticipates Elfabrio sales to generate approximately $33 million to $35 million, while Elelyso sales are expected to range from $20 million to $23 million, reflecting positive market demand expectations for its products.
  • Competitive Market Challenges: Despite facing oral competition pressures for Elfabrio, Protalix aims to bolster investor confidence through milestone-backed revenue guidance, demonstrating its strategic resilience in a competitive biopharmaceutical landscape.
Yahoo Finance
9.5
05-13Yahoo Finance
Protalix BioTherapeutics Reports Q1 Earnings
  • Earnings Performance: Protalix BioTherapeutics reported a profit of $18.3 million in Q1, translating to earnings of $0.22 per share, indicating robust growth in the drug development sector and boosting investor confidence.
  • Revenue Growth: The company posted quarterly revenue of $33.8 million, reflecting an increase compared to the previous year, which demonstrates sustained demand for its products in the market and further solidifies its market position.
  • Full-Year Revenue Outlook: Protalix expects full-year revenue to range between $78 million and $83 million, signaling strong confidence in future business development, which may attract more investor interest.
  • Market Reaction: With the growth in earnings and revenue, Protalix's stock is likely to experience positive impacts, enhancing investor expectations for its future performance and further driving the company's competitiveness in the biopharmaceutical industry.
seekingalpha
9.5
05-12seekingalpha
Protalix BioTherapeutics Set to Announce Q1 Earnings on May 13
  • Earnings Announcement: Protalix BioTherapeutics (PLX) is set to announce its Q1 2023 earnings on May 13 before market open, with consensus EPS estimate at -$0.01 and revenue expected at $11.47 million, reflecting a 13.5% year-over-year growth.
  • Historical Performance: Over the past year, PLX has beaten EPS estimates 50% of the time and has achieved a 100% success rate in beating revenue estimates, indicating a stable performance that may bolster investor confidence.
  • Future Guidance: Protalix targets revenue between $78 million and $83 million for 2026, contingent on achieving EU milestones, which could positively impact the company's long-term growth trajectory if realized.
  • Competitive Pressure: Despite Protalix's solid revenue performance, its product Elfabrio faces challenges from oral competitors, which may affect its market share and future financial outcomes.
NASDAQ.COM
9.5
03-19NASDAQ.COM
Protalix BioTherapeutics Reports FY 2025 Results with Mixed Performance
  • Product Sales Performance: Protalix reported product sales of $51.8 million for FY 2025, a slight decline from $53.0 million in 2024, primarily due to reduced sales to partner Chiesi, although increased demand from Pfizer and Brazil's Fiocruz partially offset this decline.
  • Financial Performance: The company reported a net loss of $6.6 million, or $(0.08) per share, compared to a net income of $2.9 million, or $0.04 per share, in 2024, indicating a significant deterioration in profitability.
  • Cash Flow Position: As of year-end 2025, Protalix had cash and cash equivalents of $30.3 million, with expectations to strengthen to about $50.0 million by April 2026, supported by a $25 million milestone payment from Chiesi.
  • Future Outlook: Management projects 2026 revenues between $78 million and $83 million, with Elfabrio sales expected to contribute $33.0 million to $35.0 million and Elelyso sales forecasted at $20.0 million to $23.0 million, indicating ongoing growth potential in rare disease therapies.
seekingalpha
9.5
03-18seekingalpha
Protalix BioTherapeutics Q4 2025 Earnings Call Insights
  • EU Dosing Approval: Protalix announced the European Commission's approval of Elfabrio's 2 mg/kg every 4-week dosing regimen, enhancing treatment options for adult Fabry disease patients and expected to significantly improve long-term management, thereby strengthening the company's competitive position in the market.
  • Revenue Growth Outlook: Management projects total revenues for 2026 to range from $78 million to $83 million, including a $25 million milestone payment from Chiesi, with expected revenue from Chiesi growing over 50%, which will further solidify the company's profitability profile.
  • Increased R&D Investment: R&D expenses reached $19.6 million in 2025, primarily driven by investments in the PRX-115 RELEASE study, which is anticipated to enhance the company's competitive edge in the uncontrolled gout market, with management expressing optimism about the product's prospects.
  • Strong Cash Position: As of December 31, 2025, Protalix's cash and cash equivalents totaled $30.3 million, with expectations to reach approximately $50 million by early 2026, providing ample financial support for executing strategies and clinical trials.
Wall Street analysts forecast PLX stock price to rise
1 Analyst Rating
Wall Street analysts forecast PLX stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
12.00
Averages
12.00
High
12.00
Current: 0.000
sliders
Low
12.00
Averages
12.00
High
12.00
Morgan Stanley
Ed Young
Equal Weight
downgrade
AI Analysis
2025-12-16
Reason
Morgan Stanley
Ed Young
Price Target
AI Analysis
2025-12-16
downgrade
Equal Weight
Reason
Morgan Stanley analyst Ed Young lowered the firm's price target on Pluxee to EUR 21 from EUR 23 and keeps an Equal Weight rating on the shares.
JPMorgan
Neutral
downgrade
2025-12-02
Reason
JPMorgan
Price Target
2025-12-02
downgrade
Neutral
Reason
JPMorgan lowered the firm's price target on Pluxee to EUR 18 from EUR 23 and keeps a Neutral rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PLX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Protalix Biotherapeutics Inc (PLX.A) is 10.50, compared to its 5-year average forward P/E of 6.46. For a more detailed relative valuation and DCF analysis to assess Protalix Biotherapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
6.46
Current PE
10.50
Overvalued PE
20.62
Undervalued PE
-7.71

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.22
Current EV/EBITDA
3.28
Overvalued EV/EBITDA
4.78
Undervalued EV/EBITDA
-7.21

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
1.77
Current PS
2.55
Overvalued PS
2.44
Undervalued PS
1.09

Financials

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Frequently Asked Questions

What is Protalix Biotherapeutics Inc (PLX) stock price today?

The current price of PLX is 2.14 USD — it has increased 1.9

What is Protalix Biotherapeutics Inc (PLX)'s business?

Protalix BioTherapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of recombinant therapeutic proteins expressed through its proprietary plant cell-based expression system, ProCellEx. In addition, the Company is developing PEGylated uricase, or PRX-115, for the treatment of uncontrolled gout, Long Acting (LA) DNase I, or PRX-119, for the treatment of NETs-related diseases, and other technologies and preclinical assets. Its ProCellEx platform is being used to manufacture both of its approved and marketed products as well as PRX-115 and PRX-119. PRX-115, a plant cell-expressed recombinant PEGylated Uricase (urate oxidase) - a chemically modified enzyme to treat uncontrolled gout. PRX-119 is a plant cell-expressed PEGylated recombinant human DNase I product candidate. Its product includes Elelyso and Elfabrio. Elelyso is an enzyme replacement therapy (ERT) for the treatment of patients with Gaucher disease.

What is the price predicton of PLX Stock?

Wall Street analysts forecast PLX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PLX is12.00 USD with a low forecast of 12.00 USD and a high forecast of 12.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Protalix Biotherapeutics Inc (PLX)'s revenue for the last quarter?

Protalix Biotherapeutics Inc revenue for the last quarter amounts to 26.33M USD, increased 160.37

What is Protalix Biotherapeutics Inc (PLX)'s earnings per share (EPS) for the last quarter?

Protalix Biotherapeutics Inc. EPS for the last quarter amounts to 0.22 USD, decreased -540.00

How many employees does Protalix Biotherapeutics Inc (PLX). have?

Protalix Biotherapeutics Inc (PLX) has 226 emplpoyees as of May 27 2026.

What is Protalix Biotherapeutics Inc (PLX) market cap?

Today PLX has the market capitalization of 172.42M USD.