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AXSM Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
260.190
Open
255.620
VWAP
252.68
Vol
770.86K
Mkt Cap
12.89B
Low
247.340
Amount
194.78M
EV/EBITDA(TTM)
--
Total Shares
51.46M
EV
12.78B
EV/OCF(TTM)
--
P/S(TTM)
17.80
Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.
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Events Timeline

(ET)
2026-06-03
07:30:00
Axsome Therapeutics Resolves Sunosi Patent Litigation
select

News

Newsfilter
8.5
06-18Newsfilter
PinnedAxsome Promotes Alzheimer's Awareness During Awareness Month
  • Impact of Alzheimer's Disease: Over 7 million individuals in the U.S. are affected by Alzheimer's disease, with projections indicating this number could rise to approximately 13 million by 2050, highlighting the significant impact on patients and nearly 13 million family members, thus underscoring the importance of brain health awareness and support.
  • Community Engagement Activities: Axsome is set to participate in more than 30 Walk to End Alzheimer's® events in New York City, aiming to raise public awareness about Alzheimer's disease and encourage individuals to adopt daily habits that support brain health.
  • Headquarters Lighting Event: Axsome's headquarters at One World Trade Center will be lit in purple on June 21 through the Spireworks program, symbolizing support for Alzheimer's patients and further enhancing public focus on the disease.
  • Collaboration with Advocacy Organizations: Axsome is partnering with various advocacy and patient organizations to provide resources and support for individuals and families affected by Alzheimer's disease, demonstrating the company's commitment to promoting brain health and disease awareness.
NASDAQ.COM
8.5
06-16NASDAQ.COM
Three Innovative Biotechs with Promising Prospects
  • Madrigal Approval: Madrigal Pharmaceuticals made history in 2024 by earning approval for Rezdiffra, the first treatment for metabolic dysfunction-associated steatohepatitis, addressing the urgent needs of millions of patients in the U.S., and is expected to see significant revenue growth over the next decade.
  • Axsome Sales Surge: Axsome Therapeutics reported first-quarter sales of $153.2 million for its Auvelity drug, a 59% year-over-year increase, and has received label expansion for treating Alzheimer's disease agitation, projecting peak sales of $8 billion in the future.
  • Kailera's Market Potential: Kailera Therapeutics focuses on developing weight loss medications and, despite not having marketed products, its leading candidate ribupatide is currently in phase 3 trials, potentially positioning it well in the rapidly growing anti-obesity market.
  • Investment Risks and Opportunities: While Madrigal and Axsome face competition and regulatory risks, their market prospects and pipeline potential make them attractive for investors, particularly for those looking at long-term investments in the biotech sector.
Fool
2.0
06-16Fool
Analysis of Three Promising Biotech Companies
  • Madrigal Pharmaceuticals Breakthrough: Madrigal Pharmaceuticals made history in 2024 by earning approval for Rezdiffra, the first medicine for metabolic dysfunction-associated steatohepatitis, with over 42,250 patients treated and a 127% year-over-year revenue increase to $311.3 million in Q1, indicating strong market demand and growth potential.
  • Axsome Therapeutics Progress: Axsome Therapeutics' Auvelity achieved $153.2 million in sales in Q1, a 59% increase year-over-year, and received label expansion for treating Alzheimer's disease agitation, with projected peak sales of $8 billion, showcasing its robust growth potential in mental health.
  • Kailera Risks and Opportunities: Kailera Therapeutics focuses on developing weight loss medications and, despite having no marketed products, its leading candidate ribupatide is in phase 3 trials, potentially positioning it in the rapidly growing anti-obesity market, appealing to risk-tolerant investors.
  • Market Competition and Challenges: While Madrigal and Axsome excel in their respective fields, they face competition from large pharmaceutical companies like Novo Nordisk, and Kailera's lack of marketed products increases investment risk, necessitating careful evaluation of potential clinical and regulatory challenges.
Newsfilter
5.0
06-04Newsfilter
Axsome Presents New SYMBRAVO Data at AHS Meeting
  • New Data Presentation: Axsome Therapeutics showcased new SYMBRAVO® data at the American Headache Society annual meeting, covering multiple studies on acute migraine treatment, highlighting its market potential and clinical value.
  • Clinical Trial Results: SYMBRAVO demonstrated sustained pain relief in the MOMENTUM and MOVEMENT trials, indicating its effectiveness in acute migraine treatment, which could drive market acceptance and sales growth.
  • Comparative Analysis: A network meta-analysis comparing SYMBRAVO with Gepants further validated its efficacy, enhancing its competitiveness and potentially attracting more attention from healthcare providers.
  • Strategic Implications: This data presentation not only underscores Axsome's leadership in the CNS field but also lays the groundwork for future product development and market expansion, further elevating the company's influence in the biopharmaceutical industry.
NASDAQ.COM
7.0
06-04NASDAQ.COM
Axsome Therapeutics Settles Patent Litigation for SUNOSI
  • Patent Litigation Settlement: Axsome Therapeutics announced a settlement with the last first-to-file generic applicant, resolving all patent litigation related to its product SUNOSI, marking a significant legal victory for the company.
  • Generic Sales Rights: Under the settlement terms, Axsome will grant five companies the right to sell generic versions of SUNOSI starting on March 1, 2040, or September 1, 2040, if pediatric exclusivity is granted, further solidifying its market position.
  • Market Exclusivity Assurance: This settlement provides long-term clarity for SUNOSI's market exclusivity, allowing Axsome to focus on expanding its CNS pipeline and advancing therapies for conditions affecting millions of patients.
  • Stock Performance: Axsome's stock has traded between $96.09 and $238.56 over the past year, closing at $233.49 on Wednesday with a 5.10% increase, reflecting positive market sentiment regarding the settlement.
seekingalpha
8.5
06-03seekingalpha
Axsome Therapeutics Settles Patent Lawsuits for Sunosi
  • Patent Lawsuit Resolution: Axsome Therapeutics announced the settlement of all patent lawsuits related to its sleep disorder therapy Sunosi, ensuring market stability and boosting investor confidence.
  • Market Access Rights: As a result of the agreements, five companies will gain rights to sell generic versions of Sunosi by 2040, positioning Axsome for long-term competitive advantages in the market.
  • Sales Performance: Sunosi generated $120.1 million in net sales last year, accounting for nearly 19% of Axsome's total product sales, demonstrating strong market performance.
  • Future Outlook: Axsome projects peak sales of its new drug Auvelity to reach at least $8 billion following approval for agitation in Alzheimer's disease, further solidifying the company's market position.
Wall Street analysts forecast AXSM stock price to rise
15 Analyst Rating
Wall Street analysts forecast AXSM stock price to rise
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
TD Cowen
Joseph Thome
Buy
maintain
$275 -> $300
AI Analysis
2026-06-17
New
Reason
TD Cowen
Joseph Thome
Price Target
$275 -> $300
AI Analysis
2026-06-17
New
maintain
Buy
Reason
TD Cowen analyst Joseph Thome raised the firm's price target on Axsome Therapeutics to $300 from $275 and keeps a Buy rating on the shares. The firm said management remains confident in Auvelity's growth potential following its recent discussion given the sales force expansion and the new Alzheimer's disease agitation indication. Cowen said its KOLs have been encouraged by the clinical data package of Auvelity across a wide range of patients with depression and believe it will continue to see adoption across the spectrum.
RBC Capital
Leonid Timashev
Outperform
maintain
$242 -> $302
2026-05-05
Reason
RBC Capital
Leonid Timashev
Price Target
$242 -> $302
2026-05-05
maintain
Outperform
Reason
RBC Capital analyst Leonid Timashev raised the firm's price target on Axsome Therapeutics to $302 from $242 and keeps an Outperform rating on the shares after its Q1 results. Auvelity in MDD - major depressive disorder - won a small topline beat, though spending grew faster than expected as the company advances toward its ADA launch in June and looks to several catalyst read-outs over FY26 to provide incremental upside, the analyst tells investors in a research note. RBC adds that it would buy the stock into strength.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for AXSM
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Valuation Metrics

The current forward P/E ratio for Axsome Therapeutics Inc (AXSM.O) is 333.33, compared to its 5-year average forward P/E of 9.67. For a more detailed relative valuation and DCF analysis to assess Axsome Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
9.67
Current PE
333.33
Overvalued PE
116.26
Undervalued PE
-96.93

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-19.75
Current EV/EBITDA
-24.83
Overvalued EV/EBITDA
63.76
Undervalued EV/EBITDA
-103.25

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1337.16
Current PS
8.07
Overvalued PS
7470.20
Undervalued PS
-4795.87

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Whales Holding AXSM

P
Pallas Capital Advisors LLC
Holding
AXSM
+32.77%
3M Return
E
Eventide Asset Management, LLC
Holding
AXSM
+30.67%
3M Return
N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
AXSM
+26.01%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
AXSM
+20.68%
3M Return
D
Deep Track Capital, LP
Holding
AXSM
+16.77%
3M Return
I
IFP Advisors, LLC
Holding
AXSM
+16.57%
3M Return

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Frequently Asked Questions

What is Axsome Therapeutics Inc (AXSM) stock price today?

The current price of AXSM is 250.5 USD — it has decreased -0.66

What is Axsome Therapeutics Inc (AXSM)'s business?

Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.

What is the price predicton of AXSM Stock?

Wall Street analysts forecast AXSM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AXSM is209.54 USD with a low forecast of 153.00 USD and a high forecast of 260.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Axsome Therapeutics Inc (AXSM)'s revenue for the last quarter?

Axsome Therapeutics Inc revenue for the last quarter amounts to 191.20M USD, increased 57.42

What is Axsome Therapeutics Inc (AXSM)'s earnings per share (EPS) for the last quarter?

Axsome Therapeutics Inc. EPS for the last quarter amounts to -1.26 USD, increased 3.28

How many employees does Axsome Therapeutics Inc (AXSM). have?

Axsome Therapeutics Inc (AXSM) has 925 emplpoyees as of June 21 2026.

What is Axsome Therapeutics Inc (AXSM) market cap?

Today AXSM has the market capitalization of 12.89B USD.