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AXSM Overview

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Intellectia

Loading chart...

High
217.440
Open
215.000
VWAP
215.95
Vol
737.76K
Mkt Cap
11.19B
Low
213.950
Amount
159.32M
EV/EBITDA(TTM)
--
Total Shares
51.46M
EV
11.08B
EV/OCF(TTM)
--
P/S(TTM)
15.45
Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.
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Events Timeline

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News

Fool
8.5
05-08Fool
Healthcare Transformation: The Rise of Data-Driven Models
  • Tempus AI's Market Potential: Tempus AI is collecting clinical and genomic data, with projected revenue of $1.27 billion in 2025, an 83% increase, positioning itself as a core player in precision medicine that enhances smart and precise medical decision-making.
  • Recursion Pharmaceuticals' Innovative Model: Recursion Pharmaceuticals generated approximately $74.7 million in revenue last year through partnerships with Bayer and Roche, despite operating expenses exceeding $722 million, its innovative drug discovery model is poised to fundamentally change the dynamics of the pharmaceutical industry.
  • Axsome Therapeutics' Rapid Growth: Axsome Therapeutics' Auvelity drug shows a rapid onset of action for major depressive disorder, reporting $191.2 million in revenue for Q1 2026, a 57% year-over-year increase, with FDA approval for Alzheimer's agitation potentially adding $2 billion in additional sales.
  • Integration Trends in Future Healthcare: These three companies represent different layers of healthcare transformation, with Tempus AI focusing on data and personalization, Recursion Pharmaceuticals on automated drug discovery, and Axsome Therapeutics on enhancing treatment efficacy, collectively driving the healthcare system towards greater precision and efficiency.
NASDAQ.COM
8.5
05-08NASDAQ.COM
Tempus AI and Others Poised to Transform Precision Medicine
  • Tempus AI's Growth Potential: Tempus AI is projected to reach $1.27 billion in revenue by 2025, an 83% increase from 2024, by collecting clinical and genomic data to assist doctors in making more precise treatment decisions, thereby positioning itself as a core player in precision medicine.
  • Revolutionizing Drug Discovery: Recursion Pharmaceuticals aims to disrupt traditional drug discovery methods by integrating high-throughput automation and machine learning; despite operating expenses exceeding $722 million in 2025, its partnerships with Bayer and Roche generated approximately $74.7 million in revenue, indicating significant market potential.
  • Rapid Advancement of Axsome Therapeutics: Axsome Therapeutics' Auvelity drug shows a rapid onset of action for major depressive disorder, with FDA approval for treating Alzheimer's agitation expected to generate an additional $2 billion in annual sales, highlighting its clinical advantage and market opportunity.
  • Transformation of Future Healthcare Systems: These three companies represent different layers of the healthcare industry's evolution, combining data-driven and precision treatment trends, and by 2030, the winners will be those who own the data, accelerate discovery, and deliver real outcomes, fundamentally reshaping the healthcare landscape.
Fool
5.0
05-05Fool
Potential Analysis of Small Biotech Stocks
  • FDA Approval for Axsome: Axsome Therapeutics' drug Auvelity received FDA approval for treating agitation associated with Alzheimer's disease, with a commercial launch set for June, which is expected to pivot the company from R&D to a multi-product commercial model, significantly enhancing its market share and revenue.
  • NovoCure's Innovative Therapy: NovoCure's Tumor Treating Fields technology was approved by the FDA for advanced pancreatic cancer, providing a non-invasive treatment option that is projected to meet the needs of over 52,000 patients in 2026, although the company continues to invest heavily in R&D, limiting short-term profitability.
  • MBX's Weight Loss Drug Development: MBX Biosciences focuses on developing long-acting protein endocrine drugs, and while it currently has no product revenue, it possesses $459.1 million in cash to fund operations through 2029, with its monthly dosing obesity candidate MBX 4291 poised to be a potential breakthrough in the market.
  • Growth Opportunities in Biotech: As Axsome, NovoCure, and MBX advance their clinical trials and commercial launches, 2026 is shaping up to be a pivotal year for validating these innovative therapies, allowing investors to capitalize on the disparity between current valuations and market potential for high returns.
seekingalpha
9.5
05-04seekingalpha
Axsome Therapeutics Q1 2026 Earnings Call Highlights
  • Significant Revenue Growth: Axsome Therapeutics reported total revenue of $191.2 million in Q1 2026, reflecting a 57% year-over-year increase, primarily driven by strong performances from Auvelity and Sunosi, indicating enhanced competitive positioning in the market.
  • FDA Approval for New Drug: The company received FDA approval for Auvelity to treat agitation associated with Alzheimer's disease, marking a significant expansion of its product line and laying the groundwork for the upcoming commercial launch.
  • Sales Team Expansion: Axsome has substantially expanded its sales force for Auvelity, now comprising approximately 630 representatives, aimed at increasing market coverage and supporting the promotion of new products, which is expected to drive future revenue growth.
  • Optimistic Long-Term Sales Outlook: Management anticipates that Auvelity could generate peak annual revenues of at least $8 billion, with sales expectations for Sunosi and SYMBRAVO ranging from $300 million to $500 million and $500 million to $1 billion respectively, reflecting strong confidence in future market potential.
Fool
9.5
05-04Fool
Axsome Therapeutics Shares Surge on FDA Approval and Strong Pipeline
  • FDA Approval: Axsome Therapeutics' flagship drug Auvelity has received FDA approval for treating agitation related to Alzheimer's disease, potentially benefiting over 5 million Americans, marking a significant advancement in the mental health sector.
  • Stock Surge: Axsome's stock has soared over 20% in the past month and jumped another 11.1% today, reflecting strong investor confidence in the company's future potential, pushing its market cap to $11 billion.
  • New Drug Development: The company recently acquired exclusive global rights to the oral inhibitor balipodect from Takeda Pharmaceuticals, now named AXS-20, with plans to initiate Phase III trials for schizophrenia later this year, further strengthening its pipeline.
  • Positive Earnings Report: Axsome's latest earnings report shows robust growth with a gross margin of 91.16% and the upcoming commercial launch of Auvelity, indicating the company's ongoing success and competitiveness in the biopharmaceutical market.
CNBC
2.0
05-04CNBC
Amazon Launches Supply Chain Services, Pressuring Logistics Stocks
  • Logistics Stocks Decline: Amazon's announcement of its own supply chain services has pressured logistics stocks, with GXO Logistics down 11%, UPS falling about 10%, and both FedEx and C.H. Robinson sinking 9%, indicating market concerns over Amazon's competitive threat.
  • Berkshire Hathaway's Steady Performance: CEO Greg Abel reassured investors at the annual shareholders meeting, leading to nearly a 1% increase in stock price, which reflects growing investor confidence in the company's future opportunities and alleviates concerns about breaking up the conglomerate.
  • Global Business Travel Group Acquisition: Long Lake's $6.3 billion acquisition of Global Business Travel Group signals confidence in AI's potential to reshape the travel sector, resulting in a 57% surge in the company's stock price, showcasing optimistic market expectations for future growth.
  • Norwegian Cruise Line Lowers Forecast: Norwegian Cruise Line's stock dropped 8% after it sharply cut its second-quarter and full-year estimates due to skyrocketing fuel prices from the U.S.-Iran conflict, reflecting market concerns about its profitability amid rising operational costs.
Wall Street analysts forecast AXSM stock price to rise
15 Analyst Rating
Wall Street analysts forecast AXSM stock price to rise
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
RBC Capital
Leonid Timashev
Outperform
maintain
$242 -> $302
AI Analysis
2026-05-05
Reason
RBC Capital
Leonid Timashev
Price Target
$242 -> $302
AI Analysis
2026-05-05
maintain
Outperform
Reason
RBC Capital analyst Leonid Timashev raised the firm's price target on Axsome Therapeutics to $302 from $242 and keeps an Outperform rating on the shares after its Q1 results. Auvelity in MDD - major depressive disorder - won a small topline beat, though spending grew faster than expected as the company advances toward its ADA launch in June and looks to several catalyst read-outs over FY26 to provide incremental upside, the analyst tells investors in a research note. RBC adds that it would buy the stock into strength.
Morgan Stanley
Equal Weight
maintain
$217 -> $242
2026-05-05
Reason
Morgan Stanley
Price Target
$217 -> $242
2026-05-05
maintain
Equal Weight
Reason
Morgan Stanley raised the firm's price target on Axsome Therapeutics to $242 from $217 and keeps an Equal Weight rating on the shares. The firm notes that its updated sales estimates for Auvelity in MDD and ADA are $2.2B and $2.1B, respectively, which remain "conservative" compared to management's $8B guidance.
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Valuation Metrics

The current forward P/E ratio for Axsome Therapeutics Inc (AXSM.O) is 333.33, compared to its 5-year average forward P/E of 1.35. For a more detailed relative valuation and DCF analysis to assess Axsome Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
1.35
Current PE
333.33
Overvalued PE
95.25
Undervalued PE
-92.56

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-19.57
Current EV/EBITDA
-21.86
Overvalued EV/EBITDA
64.01
Undervalued EV/EBITDA
-103.14

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1341.20
Current PS
7.11
Overvalued PS
7478.49
Undervalued PS
-4796.10

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Whales Holding AXSM

N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
AXSM
+18.11%
3M Return
P
Perceptive Advisors LLC
Holding
AXSM
+16.35%
3M Return
I
IFP Advisors, LLC
Holding
AXSM
+15.60%
3M Return
A
Algert Global LLC
Holding
AXSM
+13.40%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
AXSM
+12.08%
3M Return
V
Vestal Point Capital, LP
Holding
AXSM
+9.90%
3M Return

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Frequently Asked Questions

What is Axsome Therapeutics Inc (AXSM) stock price today?

The current price of AXSM is 216.47 USD — it has decreased -0.42

What is Axsome Therapeutics Inc (AXSM)'s business?

Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.

What is the price predicton of AXSM Stock?

Wall Street analysts forecast AXSM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AXSM is209.54 USD with a low forecast of 153.00 USD and a high forecast of 260.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Axsome Therapeutics Inc (AXSM)'s revenue for the last quarter?

Axsome Therapeutics Inc revenue for the last quarter amounts to 191.20M USD, increased 57.42

What is Axsome Therapeutics Inc (AXSM)'s earnings per share (EPS) for the last quarter?

Axsome Therapeutics Inc. EPS for the last quarter amounts to -1.26 USD, increased 3.28

How many employees does Axsome Therapeutics Inc (AXSM). have?

Axsome Therapeutics Inc (AXSM) has 925 emplpoyees as of May 12 2026.

What is Axsome Therapeutics Inc (AXSM) market cap?

Today AXSM has the market capitalization of 11.19B USD.