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VRTX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
464.980
Open
462.170
VWAP
455.67
Vol
2.99M
Mkt Cap
114.63B
Low
450.390
Amount
1.36B
EV/EBITDA(TTM)
21.42
Total Shares
253.81M
EV
107.38B
EV/OCF(TTM)
25.32
P/S(TTM)
9.51
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
Show More

Events Timeline

(ET)
2026-06-05
12:10:00
Vertex Pharmaceuticals Shows ALYFTREK's Potential Impact in Children Aged 2 to 5
select
2026-06-01 (ET)
2026-06-01
08:20:00
Vertex Pharmaceuticals' BLA for Povetacicept Accepted by FDA
select
2026-05-21 (ET)
2026-05-21
13:00:00
Vertex Pharmaceuticals' Suzetrigine New Drug Submission Accepted for Review by Health Canada
select
2026-05-06 (ET)
2026-05-06
07:30:00
Vertex Pharmaceuticals Signs Reimbursement Agreement for CASGEVY with GKV
select

News

Fool
8.5
06-20Fool
Investment Opportunities in Healthcare Sector
  • Vertex Pharmaceuticals' Market Leadership: Vertex Pharmaceuticals leads the global cystic fibrosis treatment market, with its flagship product Trikafta and the newly launched Alyftrek contributing to a 25% growth in the recent quarter, indicating strong market demand and future growth potential.
  • Intuitive Surgical's Competitive Advantage: As the global leader in robotic surgery, Intuitive Surgical ensures long-term revenue growth through its Da Vinci robot and recurring service contract revenues, while the high investment cost of its robotic systems encourages hospitals to stick with their purchases for extended periods.
  • Strong Financial Performance: Johnson & Johnson achieved nearly 10% revenue growth in Q1, with expectations to reach $100 billion in revenue for 2023, supported by 28 projects generating over $1 billion annually, providing a robust foundation for future growth.
  • Sustained Dividend Growth: Johnson & Johnson, known as a 'Dividend King', recently raised its dividend for the 64th consecutive year, demonstrating its commitment to shareholder returns and reflecting the company's stable earnings growth and financial health.
NASDAQ.COM
8.5
06-20NASDAQ.COM
Investment Opportunities in Healthcare Sector
  • Vertex Pharmaceuticals' Market Leadership: Vertex Pharmaceuticals is the global leader in cystic fibrosis treatment, with its top drug Trikafta and the newly launched Alyftrek contributing to a 25% growth in the recent quarter, indicating strong market demand and future expansion potential.
  • Intuitive Surgical's Competitive Advantage: As the global leader in robotic surgery, Intuitive Surgical has established a strong moat with its Da Vinci robot, ensuring hospitals' long-term investment in its equipment, which guarantees a continuous revenue stream, especially as service contracts and accessory sales constitute a larger share of revenue.
  • Robust Financial Growth: Johnson & Johnson achieved nearly 10% revenue growth in Q1 2023, with expectations to reach $100 billion in revenue this year, and its 28 programs generating over $1 billion annually lay a solid foundation for future double-digit growth.
  • Commitment to Dividend Growth: As a Dividend King, Johnson & Johnson has raised its dividend for the 64th consecutive year, demonstrating its focus on shareholder returns and reflecting its stable earnings growth capability, making it an ideal long-term investment.
Fool
7.5
06-20Fool
Vertex and Eli Lilly's Market Competition in Pain Management
  • Vertex Drug Approval: Vertex Pharmaceuticals' Journavx has become the first FDA-approved non-opioid pain signal inhibitor, marking a significant breakthrough in acute pain management, with expected sales growth over the coming years that will help reduce reliance on cystic fibrosis drugs.
  • Eli Lilly Acquisitions: Last year, Eli Lilly acquired SiteOne Therapeutics for up to $1 billion, gaining the non-opioid chronic pain treatment STC-004, and recently announced the acquisition of 4E Therapeutics, further enhancing its competitive position in the pain management market.
  • Market Potential: Vertex estimates that there are 80 million acute pain patients in North America and Europe, providing both Vertex and Eli Lilly opportunities to profit in this market; although Vertex currently leads, Eli Lilly's R&D progress could shift the competitive landscape.
  • Strong Financial Performance: Despite Vertex's underperformance over the past 12 months, it expects to generate at least $500 million in revenue this year from Journavx and gene-editing drug Casgevy, indicating potential in new drug launches, while Eli Lilly is also viewed as a strong investment due to its robust pipeline and profitability.
NASDAQ.COM
7.5
06-20NASDAQ.COM
Vertex and Eli Lilly Compete in Non-Opioid Pain Management Market
  • Intensifying Market Competition: Vertex Pharmaceuticals leads the non-opioid pain management market with its FDA-approved Journavx, the first oral non-opioid pain signal inhibitor, which, despite currently low revenue, is expected to see significant sales growth in the coming years and may expand into diabetic peripheral neuropathy (DPN) treatment.
  • Acquisition Strategy: Eli Lilly is actively entering the non-opioid pain management space through acquisitions, including SiteOne Therapeutics for up to $1 billion and 4E Therapeutics, whose lead asset 4ET1103 demonstrated a robust safety profile in phase 1 studies, indicating Lilly's potential in this market.
  • Vast Market Opportunity: Vertex estimates that there are 80 million patients suffering from acute pain in North America and Europe, with several million more in niche markets like DPN, providing significant market opportunities for both Vertex and Eli Lilly; while Vertex currently holds the lead, Lilly could dominate if its products demonstrate superior efficacy.
  • Strong Financial Performance: Although Vertex has lagged broader equities over the past 12 months, its dominance in the cystic fibrosis market ensures solid financial results, with expectations of at least $500 million in revenue this year from Journavx and gene editing drug Casgevy, highlighting the company's potential in new product launches.
Yahoo Finance
7.5
06-20Yahoo Finance
Vertex and Eli Lilly's Market Competition in Pain Management
  • Market Leadership: Vertex Pharmaceuticals holds a monopoly in the cystic fibrosis (CF) drug market, while Eli Lilly excels in anti-obesity medications and diabetes care, although both companies are actively seeking to reduce their reliance on their core markets.
  • Non-Opioid Drug Innovation: Vertex's Journavx became the first oral non-opioid pain signal inhibitor approved by the FDA, and while it has not generated significant revenue yet, sales are expected to ramp up over the next few years, helping the company decrease its dependence on CF products.
  • Acquisition Strategy: Eli Lilly acquired SiteOne Therapeutics last year for up to $1 billion, securing the key asset STC-004, a non-opioid treatment for chronic pain, and recently announced the acquisition of 4E Therapeutics, further expanding its footprint in the non-opioid pain treatment space.
  • Market Opportunity: Vertex estimates that there are 80 million patients suffering from acute pain in North America and Europe, providing both Vertex and Eli Lilly with significant profit potential in this market; despite Vertex's first-mover advantage, Eli Lilly could still dominate if its candidates demonstrate superior efficacy.
Fool
8.5
06-18Fool
CRISPR Therapeutics Faces Commercialization Challenges
  • Slow Commercialization: CRISPR Therapeutics' gene-editing therapy CASGEVY was approved in late 2023, yet by Q1 2026, it reported only $1.46 million in revenue against a net loss of $122.9 million, highlighting the lengthy transition from scientific breakthrough to commercial product.
  • Strong Financial Position: The company ended Q1 with approximately $2.4 billion in cash and equivalents, providing substantial financial flexibility to support ongoing research programs without the need for immediate capital raising, thus ensuring long-term viability.
  • Significant Market Potential: CTX112, an investigational CAR-T therapy, could see its market value exceed $22 billion by 2033, and capturing just 5% of this market would imply over $1 billion in annual revenue potential, indicating its promising future in cancer treatment.
  • Patient Adoption Challenges: While the company has increased authorized treatment centers in the U.S. and Europe, the complexity of gene-editing therapies and lengthy approval processes hinder rapid commercialization, necessitating careful observation of patient volume growth in the coming years.
Wall Street analysts forecast VRTX stock price to rise
22 Analyst Rating
Wall Street analysts forecast VRTX stock price to rise
17 Buy
5 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Truist
NULL
to
Buy
initiated
$525 -> $542
AI Analysis
2026-05-27
Reason
Truist
Price Target
$525 -> $542
AI Analysis
2026-05-27
initiated
NULL
to
Buy
Reason
Truist assumed coverage of Vertex Pharmaceuticals with a Buy rating and price target of $542, up from $525. The firm believes Vertex's emerging kidney franchise can grow into blockbuster assets and further diversify the company's product portfolio.
Barclays
NULL -> Overweight
maintain
$607 -> $615
2026-05-06
Reason
Barclays
Price Target
$607 -> $615
2026-05-06
maintain
NULL -> Overweight
Reason
Barclays raised the firm's price target on Vertex Pharmaceuticals to $615 from $607 and keeps an Overweight rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VRTX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 23.75, compared to its 5-year average forward P/E of 186.83. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
186.83
Current PE
23.75
Overvalued PE
780.60
Undervalued PE
-406.94

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
23.24
Current EV/EBITDA
19.64
Overvalued EV/EBITDA
47.13
Undervalued EV/EBITDA
-0.65

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.67
Current PS
8.03
Overvalued PS
10.12
Undervalued PS
7.23

Financials

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3M Return
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3M Return
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ProFund Advisors LLC
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Security Investors, LLC
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Capital Research
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Frequently Asked Questions

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?

The current price of VRTX is 451.63 USD — it has decreased -1.6

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).

What is the price predicton of VRTX Stock?

Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is515.88 USD with a low forecast of 414.00 USD and a high forecast of 604.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

Vertex Pharmaceuticals Inc revenue for the last quarter amounts to 2.99B USD, increased 7.82

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

Vertex Pharmaceuticals Inc. EPS for the last quarter amounts to 4.02 USD, increased 61.45

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?

Vertex Pharmaceuticals Inc (VRTX) has 6400 emplpoyees as of June 21 2026.

What is Vertex Pharmaceuticals Inc (VRTX) market cap?

Today VRTX has the market capitalization of 114.63B USD.