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VRTX Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
431.940
Open
422.370
VWAP
427.62
Vol
953.35K
Mkt Cap
109.09B
Low
421.110
Amount
407.67M
EV/EBITDA(TTM)
20.32
Total Shares
253.81M
EV
101.84B
EV/OCF(TTM)
24.02
P/S(TTM)
9.05
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
Show More

Events Timeline

(ET)
2026-05-06
07:30:00
Vertex Pharmaceuticals Signs Reimbursement Agreement for CASGEVY with GKV
select
2026-05-04 (ET)
2026-05-04
19:50:00
Escalating Geopolitical Tensions in the Middle East Increase Market Volatility
select
2026-05-04
18:30:00
Vertex Discontinues VX-522 Clinical Trial
select
link
2026-05-04
16:10:00
Vertex Pharmaceuticals Confirms FY26 Revenue of $12.95B-$13.1B
select
2026-05-04
16:10:00
Vertex Reports Q1 Revenue of $2.99B, Slightly Below Expectations
select

News

seekingalpha
9.5
05-08seekingalpha
PinnedVertex Pharmaceuticals Set to Announce Q2 Earnings on May 11
  • Earnings Announcement: Vertex Pharmaceuticals is set to release its Q2 2023 earnings report on May 11 after market close, with consensus EPS estimate at $4.75, reflecting a 5.1% year-over-year increase, and revenue estimate at $3.22 billion, up 8.8% year-over-year.
  • Historical Performance Review: Over the past two years, Vertex has exceeded EPS estimates 50% of the time and revenue estimates 63% of the time, indicating a degree of stability in its financial performance amidst market fluctuations.
  • Expectation Adjustment Dynamics: In the last three months, EPS estimates have seen 2 upward revisions and 9 downward revisions, while revenue estimates experienced 8 upward revisions and 4 downward revisions, reflecting market uncertainty regarding the company's future performance.
  • Long-term Revenue Outlook: Vertex projects revenue for 2026 to be between $12.95 billion and $13.1 billion, while targeting over $500 million from non-CF products, showcasing the company's strategic focus on diversifying its product lines.
Fool
9.5
05-06Fool
Vertex Pharmaceuticals: Investment Returns and Future Outlook
  • Significant Investment Returns: An investment of $20,000 in Vertex Pharmaceuticals during its 1991 IPO would now exceed $1 million, reflecting a commendable 14% compound annual growth rate, which outperforms the S&P 500's 11% over the same period, indicating the company's robust long-term growth potential.
  • Core Market Dominance: Vertex Pharmaceuticals leads the cystic fibrosis (CF) market, treating approximately 95% of CF patients in the U.S., although its revenue growth has slowed, with an 8% year-over-year increase to $2.99 billion in Q1, suggesting sustained market demand despite challenges.
  • Diversification Challenges: While Vertex aims to reduce its reliance on CF, it anticipates $500 million in non-CF revenue this year, a significant increase from $10 million in 2024, yet this growth remains insufficient, highlighting ongoing challenges in its diversification efforts.
  • Future Growth Potential: Vertex is seeking approval for Casgevy, a gene-editing drug for sickle cell disease and transfusion-dependent beta-thalassemia, which could drive future growth, alongside advancing povetacicept for IgA nephropathy, showcasing the potential for an expanded product portfolio.
NASDAQ.COM
9.5
05-06NASDAQ.COM
Vertex Pharmaceuticals' Future Outlook Appears Promising
  • Core Business Slowdown: Vertex Pharmaceuticals reported an 8% year-over-year revenue increase to $2.99 billion in Q1, which, while not terrible, reflects a general downward trend in growth over recent years, indicating weakness in its core market.
  • Non-CF Revenue Potential: The company expects at least $500 million in non-CF revenue for 2023, a significant increase from $10 million in 2024, suggesting that its diversification efforts are beginning to pay off.
  • New Drug Development Progress: Vertex is seeking approval for Casgevy, a gene-editing medicine for sickle cell disease and transfusion-dependent beta-thalassemia, aimed at providing early treatment for patients aged 5 to 11, highlighting its significant market potential.
  • Future Growth Outlook: As Vertex continues to develop new products in the CF space and expand its portfolio, it is expected to achieve stronger revenue and earnings growth in the coming years, presenting a positive long-term outlook.
Yahoo Finance
2.0
05-05Yahoo Finance
Vertex Pharmaceuticals Confident in Renal Franchise
  • Renal Business Outlook: Vertex Pharmaceuticals (VRTX) management expresses strong confidence in its emerging renal franchise, indicating that the strategic positioning in this area is beginning to yield results, which is expected to drive future revenue growth.
  • Market Potential: With the increasing global demand for treatments for kidney diseases, Vertex's renal product line is poised to capture significant market share in the coming years, thereby enhancing the company's overall competitiveness.
  • R&D Investment: The company continues to increase its investment in research and development related to kidney diseases, aiming to meet unmet medical needs through innovative therapies, further solidifying its leadership position in the biopharmaceutical industry.
  • Management Confidence: The management's confidence reflects a positive assessment of product development progress, which is expected to attract more investor attention and improve the company's performance in the capital markets.
Fool
8.5
05-05Fool
Pinterest Surges on Record User Growth and Positive Revenue Guidance
  • Strong User Growth: Pinterest (PINS) surged over 15% ahead of market open, driven by an 11% year-over-year increase in monthly active users (MAU), marking the tenth consecutive quarter of double-digit growth, indicating that enhanced user engagement will support future profitability.
  • Optimistic Revenue Guidance: Pinterest's revenue guidance exceeded expectations, with CEO Bill Ready emphasizing the company's commitment to aligning profitability with user engagement, thereby boosting investor confidence and driving stock price increases.
  • Positive Market Reaction: Analyst Rich Greifner highlighted that Pinterest's large and engaged user base, characterized by high commercial intent, makes it an attractive platform for advertisers, further solidifying its competitive position in the advertising market.
  • Favorable Industry Outlook: As Pinterest's user growth and revenue expectations improve, market confidence in its future performance is likely to attract more investor interest, propelling further development in the social media sector.
seekingalpha
9.5
05-05seekingalpha
Vertex Pharmaceuticals Q1 2026 Earnings Highlights
  • Significant Revenue Growth: Vertex Pharmaceuticals reported total product revenue of $2.99 billion for Q1 2026, reflecting an 8% year-over-year increase, with CASGEVY and JOURNAVX contributing approximately 25% to this growth, indicating strong performance in non-CF products.
  • ALYFTREK Milestone: ALYFTREK has surpassed $1 billion in cumulative global revenue, and the U.S. label expansions present a meaningful commercial opportunity for approximately 800 newly eligible patients, further solidifying the company's position in the CF market.
  • VX-522 Program Termination: Vertex has chosen to discontinue the VX-522 program due to tolerability issues, which means the company will not be able to assess its efficacy or safety; however, this shift allows a focus on alternative treatment modalities to ensure product line diversity in the future.
  • Optimistic Outlook: The company reiterated its total revenue guidance for 2026 at $12.95 billion to $13.1 billion, with expectations for non-CF product revenue exceeding $500 million, reflecting strong market demand and growth potential for CASGEVY and JOURNAVX.
Wall Street analysts forecast VRTX stock price to rise
22 Analyst Rating
Wall Street analysts forecast VRTX stock price to rise
17 Buy
5 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Barclays
NULL -> Overweight
maintain
$607 -> $615
AI Analysis
2026-05-06
New
Reason
Barclays
Price Target
$607 -> $615
AI Analysis
2026-05-06
New
maintain
NULL -> Overweight
Reason
Barclays raised the firm's price target on Vertex Pharmaceuticals to $615 from $607 and keeps an Overweight rating on the shares.
Morgan Stanley
analyst
Overweight
maintain
$612 -> $616
2026-05-05
Reason
Morgan Stanley
analyst
Price Target
$612 -> $616
2026-05-05
maintain
Overweight
Reason
Morgan Stanley raised the firm's price target on Vertex Pharmaceuticals to $616 from $612 and keeps an Overweight rating on the shares. Q1 results were "uneventful" and FY26 guidance was reiterated, notes the analyst, who says that kidney pipeline execution remains the focus.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VRTX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 22.57, compared to its 5-year average forward P/E of 187.01. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
187.01
Current PE
22.57
Overvalued PE
781.25
Undervalued PE
-407.22

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
23.06
Current EV/EBITDA
18.42
Overvalued EV/EBITDA
47.03
Undervalued EV/EBITDA
-0.90

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.67
Current PS
7.55
Overvalued PS
10.12
Undervalued PS
7.21

Financials

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Whales Holding VRTX

P
ProFund Advisors LLC
Holding
VRTX
+21.50%
3M Return
B
Bluebox Asset Management Uk Ltd.
Holding
VRTX
+20.01%
3M Return
H
Hudson Bay Capital Management LP
Holding
VRTX
+18.13%
3M Return
O
Osmosis Investment Management UK Limited
Holding
VRTX
+16.21%
3M Return
N
Nomura Asset Management Taiwan Ltd.
Holding
VRTX
+16.02%
3M Return
S
Security Investors, LLC
Holding
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+15.35%
3M Return

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Frequently Asked Questions

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?

The current price of VRTX is 429.82 USD — it has increased 1.13

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).

What is the price predicton of VRTX Stock?

Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is515.88 USD with a low forecast of 414.00 USD and a high forecast of 604.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

Vertex Pharmaceuticals Inc revenue for the last quarter amounts to 2.99B USD, increased 7.82

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

Vertex Pharmaceuticals Inc. EPS for the last quarter amounts to 4.02 USD, increased 61.45

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?

Vertex Pharmaceuticals Inc (VRTX) has 6400 emplpoyees as of May 11 2026.

What is Vertex Pharmaceuticals Inc (VRTX) market cap?

Today VRTX has the market capitalization of 109.09B USD.