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VRTX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
500.000
Open
498.000
VWAP
493.04
Vol
1.36M
Mkt Cap
126.81B
Low
488.870
Amount
673.23M
EV/EBITDA(TTM)
24.57
Total Shares
254.03M
EV
120.31B
EV/OCF(TTM)
33.13
P/S(TTM)
10.73
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
Show More

Events Timeline

(ET)
2026-03-10
10:00:00
Vertex Stock Rises $42.53 to $503.40
select
2026-03-10
09:00:00
Stock Futures Lower as Oil Prices Retreat, Easing Inflation Fears
select

News

Benzinga
9.5
03-10Benzinga
PinnedVertex Achieves Phase 3 Trial Success, Boosting Stock Performance
  • Clinical Trial Success: Vertex's Phase 3 RAINIER trial met its primary objective, achieving a 52% reduction in urine protein to creatinine ratio (UPCR) at Week 36, indicating strong potential for povetacicept in treating IgAN and positioning it as a market leader.
  • FDA Review Progress: The FDA has initiated a rolling review of the Biologics License Application for povetacicept, with Vertex planning to complete its submission by the end of March, which could accelerate product launch and enhance future revenue expectations for the company.
  • Analyst Optimism: Analyst William Blair raised the probability of success for povetacicept from 70% to 90%, anticipating potential approval by year-end under priority review, although material revenue is not expected until 2027 due to reimbursement dynamics.
  • Stock Performance Analysis: Vertex shares rose 6.32% to $489.99 in premarket trading, reflecting positive market reaction to the clinical data, despite a 7.83% decline over the past year, indicating resilience as the stock approaches its 52-week highs.
NASDAQ.COM
4.5
15:03 PMNASDAQ.COM
Analysis of TQQQ ETF's 52-Week Price Fluctuations
  • Price Range Analysis: TQQQ ETF's 52-week low is $17.50 per share, with a high of $60.685, while the latest trade stands at $49.39, indicating relative stability in a volatile market that may attract investor interest.
  • Technical Analysis Tool: Comparing the latest share price to the 200-day moving average provides investors with valuable insights for technical analysis, aiding in market trend assessment and potential buying opportunities to optimize investment decisions.
  • ETF Unit Trading Mechanism: ETFs trade like stocks, where investors buy and sell 'units' that can be created or destroyed based on demand, offering flexibility that enhances liquidity in the market.
  • Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding helps identify ETFs experiencing notable inflows (new units created) or outflows (old units destroyed), as these liquidity shifts can impact the performance of individual stocks held within the ETFs.
Barron's
4.5
03-10Barron's
Stocks Close Steady as Oil Prices Drop Significantly
  • Session Outcome: The recent session concluded with a lack of significant developments, leaving many feeling underwhelmed.
  • Mixed Signals: The overall messaging from the session was inconsistent, contributing to confusion among participants.
  • Expectations vs. Reality: Anticipated outcomes did not materialize, leading to disappointment among stakeholders.
  • Future Implications: The session's lack of decisive action may have repercussions for future discussions and decisions.
Barron's
4.5
03-10Barron's
U.S. Markets Closed with Mixed Results on Tuesday, Driven by BridgeBio Pharma's Gains and Centene's Declines
  • U.S. Stock Market Performance: U.S. stock indexes closed mixed on Tuesday, with overall performance remaining flat.
  • Index Movements: The Dow Jones Industrial Average dropped by 0.07%, while the S&P 500 fell by 0.21%.
Benzinga
8.5
03-10Benzinga
CRISPR Therapeutics to Issue $350 Million Convertible Notes
  • Convertible Note Offering: CRISPR Therapeutics plans to issue $350 million in convertible senior notes due in 2031 through a private placement aimed at qualified institutional investors, which is expected to enhance the company's capital structure and liquidity.
  • Bond Terms Details: Under Rule 144A of the Securities Act, the notes will rank as senior unsecured obligations, with interest payments occurring biannually, starting in September 2026, providing a stable cash inflow to support ongoing R&D activities.
  • Use of Proceeds: While management did not specify particular spending priorities, the proceeds are expected to be allocated toward general corporate purposes, potentially including further development of gene-editing therapies targeting blood disorders and oncology.
  • Recent Earnings Performance: The company's latest gene-editing therapy, Casgevy, generated $54 million in revenue for the fourth quarter and $116 million for the full year, indicating strong market potential and demand for its products, despite an 8.54% drop in stock price at the time of publication.
CNBC
2.0
03-10CNBC
Hims & Hers Shares Rise, BioNTech Crashes Amid Leadership Changes
  • Hims & Hers Stock Surge: Shares of Hims & Hers rose 3% after Bank of America upgraded the stock from underperform to neutral, indicating market optimism about its potential to sell Novo's Ozempic and Wegovy drugs on its platform.
  • BioNTech Shares Plummet: BioNTech's stock crashed over 20% following the announcement of its co-founders' departure to establish an independent company, alongside a reported fourth-quarter net loss of €305 million, highlighting deteriorating financial conditions.
  • SolarEdge Stock Rises: Following Bank of America's upgrade to neutral, SolarEdge shares surged nearly 10%, reflecting increased market confidence in its improved margin trajectory, revenue stability, and liquidity.
  • United Natural Foods Lowers Guidance: The grocery distributor reported second-quarter revenue of $7.95 billion, missing the $8.11 billion expected, and lowered its full-year revenue guidance to $31 billion to $31.4 billion, indicating ongoing market challenges.
Wall Street analysts forecast VRTX stock price to rise
22 Analyst Rating
Wall Street analysts forecast VRTX stock price to rise
17 Buy
5 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Jefferies
Buy
initiated
$580
AI Analysis
2026-03-10
New
Reason
Jefferies
Price Target
$580
AI Analysis
2026-03-10
New
initiated
Buy
Reason
Jefferies initiated coverage of Vertex Pharmaceuticals with a Buy rating and $580 price target. The stock has underperformed its peers over the past six months following several setbacks last year, notes the analyst, ho sees upside for povetacicept, which it thinks has the potential to diversify Vertex beyond cystic fibrosis.
Citi
Geoff Meacham
Buy
maintain
$575 -> $585
2026-03-10
New
Reason
Citi
Geoff Meacham
Price Target
$575 -> $585
2026-03-10
New
maintain
Buy
Reason
Citi analyst Geoff Meacham raised the firm's price target on Vertex Pharmaceuticals to $585 from $575 and keeps a Buy rating on the shares. The company reported positive Phase 3 data for povetacicept in proteinuria, the analyst tells investors in a research note. Citi upped its estimates for the povetacicept program, seeing broad usage potential.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VRTX
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Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 22.55, compared to its 5-year average forward P/E of 192.95. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
192.95
Current PE
22.55
Overvalued PE
797.14
Undervalued PE
-411.24

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
22.88
Current EV/EBITDA
16.66
Overvalued EV/EBITDA
47.36
Undervalued EV/EBITDA
-1.60

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.67
Current PS
8.97
Overvalued PS
10.15
Undervalued PS
7.20

Financials

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Whales Holding VRTX

H
Hardman Johnston Global Advisors LLC
Holding
VRTX
+18.55%
3M Return
F
Freemont Capital Pte. Ltd.
Holding
VRTX
+14.45%
3M Return
N
Nomura Asset Management Taiwan Ltd.
Holding
VRTX
+7.51%
3M Return
B
Bowen, Hanes & Company, Inc.
Holding
VRTX
+7.21%
3M Return
S
Sofinnova Investment, Inc.
Holding
VRTX
+5.81%
3M Return
G
Grandfield & Dodd, LLC
Holding
VRTX
+5.10%
3M Return

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Frequently Asked Questions

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?

The current price of VRTX is 490.2364 USD — it has decreased -1.79

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).

What is the price predicton of VRTX Stock?

Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is515.88 USD with a low forecast of 414.00 USD and a high forecast of 604.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

Vertex Pharmaceuticals Inc revenue for the last quarter amounts to 3.19B USD, increased 9.55

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

Vertex Pharmaceuticals Inc. EPS for the last quarter amounts to 4.65 USD, increased 30.99

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?

Vertex Pharmaceuticals Inc (VRTX) has 6400 emplpoyees as of March 11 2026.

What is Vertex Pharmaceuticals Inc (VRTX) market cap?

Today VRTX has the market capitalization of 126.81B USD.