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VRTX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
448.350
Open
443.430
VWAP
445.66
Vol
1.63M
Mkt Cap
113.44B
Low
442.085
Amount
724.17M
EV/EBITDA(TTM)
21.66
Total Shares
254.03M
EV
106.08B
EV/OCF(TTM)
29.21
P/S(TTM)
9.53
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
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Events Timeline

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News

seekingalpha
8.5
03-31seekingalpha
PinnedVertex Pharmaceuticals Submits BLA for IgAN Treatment
  • Application Progress: Vertex Pharmaceuticals has completed its rolling Biologics License Application (BLA) submission for povetacicept, aimed at treating immunoglobulin A nephropathy (IgAN), with an expected FDA review completion within six months of acceptance, indicating the company's proactive stance in drug development.
  • Priority Review Utilization: The application leverages a priority review voucher to expedite the FDA review process, thereby shortening the time to market and enhancing Vertex's position in the competitive biopharmaceutical landscape.
  • Drug Mechanism: Povetacicept acts as a dual antagonist of B cell activating factor (BAFF) and proliferation-inducing ligand (APRIL) cytokines, both of which play crucial roles in the pathogenesis of various autoimmune diseases, highlighting its therapeutic potential for IgAN.
  • Market Outlook: Given the rising demand for treatments for autoimmune diseases, the successful launch of povetacicept could present significant market opportunities for Vertex, potentially driving future revenue growth and enhancing shareholder value.
NASDAQ.COM
4.5
03-31NASDAQ.COM
CGGR Stock Price Analysis and ETF Dynamics
  • Price Fluctuation Analysis: CGGR's 52-week low is $29.23 and high is $45.835, with the latest trade at $39.55, indicating price volatility within this range that may influence investor buying decisions.
  • Technical Analysis Tool: Comparing the latest stock price to the 200-day moving average can provide investors with valuable insights for technical analysis, helping to assess market trends and potential buying opportunities.
  • ETF Trading Mechanism: Exchange-traded funds (ETFs) trade similarly to stocks, where investors are buying and selling 'units' that can be created or destroyed based on investor demand, impacting liquidity and market performance.
  • Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding for ETFs focuses on those experiencing notable inflows (new units created) or outflows (old units destroyed), assessing their impact on underlying assets and market sentiment.
NASDAQ.COM
2.0
03-28NASDAQ.COM
Trump Bull Market May End, Three Stocks Still Poised to Rise
  • Market Uncertainty: The attack by the U.S. and Israel on Iran has disrupted traffic through the Strait of Hormuz, leading to rising oil prices that are expected to increase overall commodity prices and exacerbate inflationary pressures, thereby affecting investor confidence.
  • Economic Slowdown: The U.S. GDP growth rate for Q4 2025 has slipped to 1.4%, coupled with a loss of 92,000 jobs in February, indicating that economic weakness may impact market performance, especially in the impending bear market.
  • Investor Safe Haven: Berkshire Hathaway is viewed as a safe haven during market turbulence, with a massive cash stockpile that allows it to acquire quality stocks at lower prices during downturns, enhancing its risk resilience.
  • Defensive Stock Advantage: Enbridge attracts many investors with a 5.2% dividend yield and a 31-year track record of dividend increases, while Vertex Pharmaceuticals' monopoly in treating cystic fibrosis positions it for potential growth even in a declining market.
Fool
5.0
03-28Fool
Prediction of the End of the Trump Bull Market
  • Market Prediction Update: The conflict between the U.S. and Iran has led to rising oil prices, with the Producer Price Index (PPI) increasing by 3.4% year-over-year, significantly exceeding economists' expectations, prompting me to revise my stock market outlook and predict the end of the Trump bull market, which may lead to increased inflation.
  • Economic Growth Slowdown: The U.S. GDP growth rate for Q4 2025 has slipped to 1.4%, partly due to the federal government shutdown, while the loss of 92,000 jobs highlights economic weakness, adding to market uncertainty.
  • Fed Policy Dilemma: With the dual pressures of high inflation and a sluggish economy, the Federal Reserve faces a tough choice; cutting rates could exacerbate inflation, while raising them might further harm job growth, leaving the market uncertain about future policy directions.
  • Defensive Stock Recommendations: Despite the potential end of the bull market, stocks like Berkshire Hathaway, Enbridge, and Vertex Pharmaceuticals are expected to rise; Berkshire's cash reserves and Enbridge's attractive dividends appeal to investors, while Vertex's unique position in healthcare makes it a strong candidate for growth.
Fool
7.0
03-27Fool
Long-Term Investment Potential in Strong Healthcare Stocks
  • Strong Market Position: Johnson & Johnson (JNJ) maintains its leadership in the healthcare sector by continuously launching new products in pharmaceuticals and medical devices, effectively managing patent expirations and competitive pressures.
  • Robust Financial Health: Johnson & Johnson boasts the highest credit rating, indicating its ability to meet financial obligations while retaining ample funds for investment, thereby strengthening its competitive edge for the next 20 years.
  • Monopoly Market Advantage: Vertex Pharmaceuticals (VRTX) holds a monopoly in the cystic fibrosis drug market, benefiting from significant pricing power due to the absence of competitors, ensuring substantial revenue and profits for the next decade.
  • Innovative Drug Development: Vertex is working on new medicines, including candidates for kidney disease and Type 1 diabetes, which are expected to drive strong returns beyond 2046, ensuring the company's long-term growth potential.
Fool
7.0
03-25Fool
Vertex Pharmaceuticals Shows Promising Future Prospects
  • Core Business Stability: Vertex Pharmaceuticals continues to rely heavily on its cystic fibrosis drugs, Trikafta and Alyftrek, which drove a 9% year-over-year revenue increase to $12 billion in 2025, with expectations for core business growth at high single or low double-digit rates over the next year, solidifying its leadership in the global market.
  • New Product Progress: The company anticipates generating at least $500 million in revenue from new products, Journavx and Casgevy, in 2025, indicating a strong performance in its non-cystic fibrosis portfolio and potentially marking the beginning of a new growth era for Vertex.
  • Pipeline Advancements: Vertex plans to seek approval for povetacicept, a therapy for IgA nephropathy, by the end of March, with potential market entry by late 2026 or early 2027, which would further enhance its product lineup.
  • Future Drug Approvals: The company also intends to request approval for Type 1 diabetes drug zimislecel this year and expects positive clinical trial results for inaxaplin, targeting APOL-1-mediated kidney disease, which could significantly boost its market competitiveness if successful in late 2026.
Wall Street analysts forecast VRTX stock price to rise
22 Analyst Rating
Wall Street analysts forecast VRTX stock price to rise
17 Buy
5 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Wells Fargo
Wells Fargo
Overweight
maintain
$515 -> $550
AI Analysis
2026-03-19
Reason
Wells Fargo
Wells Fargo
Price Target
$515 -> $550
AI Analysis
2026-03-19
maintain
Overweight
Reason
Wells Fargo raised the firm's price target on Vertex Pharmaceuticals to $550 from $515 and keeps an Overweight rating on the shares. The firm thinks new drugs and mechanisms such as CD20, BAFF/APRILs, and next generation complement Inhibitors have potential to expand the generalized Myasthenia Gravis market by more than threefold in the next 10 years, to $15B U.S. and $20B global sales in 2036. Vertex Pharmaceuticals (VRTX), Amgen (AMGN) and Regeneron (REGN) could be the biggest beneficiaries here, and Wells is of the view that there is upside to Street numbers.
Maxim
Hold
to
Buy
upgrade
$575
2026-03-18
Reason
Maxim
Price Target
$575
2026-03-18
upgrade
Hold
to
Buy
Reason
Maxim upgraded Vertex Pharmaceuticals to Buy from Hold with a $575 price target. The firm believes povetacicept can be a blockbuster and has "pipeline-in-a-product potential." When combined with the contributions from Journavx and Casgevy, Vertex has three products that "could move the needle" and provide diversification from the cystic fibrosis franchise, the analyst tells investors in a research note. Maxim views the shares as an attractive investment in a challenging biotech and macro environment.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VRTX
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Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 22.55, compared to its 5-year average forward P/E of 195.02. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
195.02
Current PE
22.55
Overvalued PE
802.46
Undervalued PE
-412.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
23.02
Current EV/EBITDA
16.66
Overvalued EV/EBITDA
47.61
Undervalued EV/EBITDA
-1.57

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.69
Current PS
8.97
Overvalued PS
10.17
Undervalued PS
7.21

Financials

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Whales Holding VRTX

H
Hardman Johnston Global Advisors LLC
Holding
VRTX
+10.93%
3M Return
F
Freemont Capital Pte. Ltd.
Holding
VRTX
+9.08%
3M Return
S
Sofinnova Investment, Inc.
Holding
VRTX
+4.93%
3M Return
B
Bowen, Hanes & Company, Inc.
Holding
VRTX
+3.20%
3M Return
A
Amundi Asset Management US, Inc.
Holding
VRTX
+1.50%
3M Return
T
Tang Capital Management, LLC
Holding
VRTX
+1.48%
3M Return

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Frequently Asked Questions

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?

The current price of VRTX is 446.54 USD — it has increased 0.76

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).

What is the price predicton of VRTX Stock?

Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is515.88 USD with a low forecast of 414.00 USD and a high forecast of 604.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

Vertex Pharmaceuticals Inc revenue for the last quarter amounts to 3.19B USD, increased 9.55

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

Vertex Pharmaceuticals Inc. EPS for the last quarter amounts to 4.65 USD, increased 30.99

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?

Vertex Pharmaceuticals Inc (VRTX) has 6400 emplpoyees as of April 01 2026.

What is Vertex Pharmaceuticals Inc (VRTX) market cap?

Today VRTX has the market capitalization of 113.44B USD.