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VRTX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
450.000
Open
448.010
VWAP
446.60
Vol
1.89M
Mkt Cap
113.59B
Low
442.250
Amount
845.58M
EV/EBITDA(TTM)
21.22
Total Shares
253.81M
EV
106.34B
EV/OCF(TTM)
25.08
P/S(TTM)
9.42
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
Show More

Events Timeline

(ET)
2026-05-21
13:00:00
Vertex Pharmaceuticals' Suzetrigine New Drug Submission Accepted for Review by Health Canada
select
2026-05-06 (ET)
2026-05-06
07:30:00
Vertex Pharmaceuticals Signs Reimbursement Agreement for CASGEVY with GKV
select
2026-05-04 (ET)
2026-05-04
19:50:00
Escalating Geopolitical Tensions in the Middle East Increase Market Volatility
select

News

Yahoo Finance
6.5
05-31Yahoo Finance
Investment Choices in Gene Editing Technology
  • Dependency of CRISPR Therapeutics: CRISPR Therapeutics relies heavily on Vertex Pharmaceuticals for the commercialization of CASGEVY, reporting a net loss of $581.6 million in fiscal 2025, which highlights the risks associated with its concentrated revenue stream, while its debt-to-equity ratio stands at 0.2, indicating low leverage.
  • Growth Potential of Editas Medicine: Editas Medicine achieved revenue of $40.5 million in fiscal 2025, reflecting a 25.4% year-over-year growth, despite a net loss of $160.1 million and a net margin of negative 395%, underscoring the high costs associated with developing genomic therapies and the potential market opportunities.
  • Risk Comparison: CRISPR Therapeutics faces legal challenges, including a patent infringement lawsuit, and its dependency on Vertex limits its revenue control, while Editas relies on third-party providers due to a lack of internal manufacturing, increasing the risk of supply chain disruptions.
  • Valuation Differences: CRISPR Therapeutics has a forward P/E ratio of 23.4x, while Editas has a P/S ratio of 8190x, indicating that Editas's stock valuation is relatively reasonable, even though CRISPR has a lead in FDA approvals, potentially giving it a market advantage.
Newsfilter
8.5
05-28Newsfilter
Avaí Bio Achieves Milestone in α-Klotho Cell Bank Development
  • Production Milestone: On May 20, 2026, Avaí Bio and Austrianova announced the completion of a GMP-grade Master Cell Bank for α-Klotho, marking a significant advancement in the anti-aging therapy field, which is expected to propel the clinical and preclinical research of α-Klotho cell therapy.
  • Regulatory Compliance Testing: The Master Cell Bank will undergo comprehensive third-party testing to ensure the absence of pathogenic viruses and contaminants, meeting the requirements of regulatory bodies such as the FDA, which is a prerequisite for advancing clinical trials.
  • Strategic Partnership Advantage: Klothonova, the joint venture between Avaí Bio and Austrianova, leverages the latter's cell encapsulation technology and GMP manufacturing capabilities, creating a unique integrated structure from development to clinic, enhancing competitiveness in the anti-aging biotech sector.
  • Future Outlook: Avaí Bio plans to present the latest data from the α-Klotho therapy at the Klotho Conference in September 2026, further increasing market visibility and laying the groundwork for long-term growth in its cell-based therapeutic platform.
seekingalpha
6.5
05-27seekingalpha
Seeking Alpha's Quant Ratings Upgrades and Downgrades Analysis
  • Investor Strategy Tool: Seeking Alpha's Quant Ratings provide investors with new methods to track market momentum and risks, analyzing financial statements, stock performance, and future earnings estimates to identify potential bullish or bearish signals.
  • Relative Industry Ranking: The system ranks stocks relative to their sectors and offers Factor Grades, allowing users to clearly see strengths and weaknesses across metrics such as value, growth, profitability, momentum, and EPS revisions, thereby optimizing investment decisions.
  • Market Sentiment Indicators: By utilizing Quant Ratings, investors can identify shifts in market sentiment earlier, enabling them to adopt more flexible investment strategies during market fluctuations and enhance portfolio resilience against risks.
  • Individual Stock Analysis Cases: The article highlights stocks like Vertex Pharmaceuticals and Keysight Technologies, which face the need for bolder M&A strategies and unsupported stock price gains, respectively, underscoring the importance of Quant Ratings in individual stock analysis.
Fool
8.5
05-26Fool
Gene Editing Sector Gains Momentum with Key Players CRISPR and Beam
  • CRISPR Therapeutics Progress: In 2023, CRISPR Therapeutics received approval for Casgevy, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
  • Pipeline Advantage: CRISPR Therapeutics boasts a deeper pipeline, including CTX310 aimed at lowering LDL cholesterol, offering a potential one-time treatment option that could enhance its market competitiveness and stock price.
  • Beam Therapeutics Innovation: Beam Therapeutics focuses on base editing technology and, while lacking marketed products, has shown strong results with its clinical candidate Risto-cel, with plans to submit a regulatory application by year-end, potentially driving stock price increases.
  • Financial Comparison: As of the end of Q1, CRISPR Therapeutics held $2.4 billion in cash and equivalents compared to Beam Therapeutics' $1.2 billion, providing CRISPR with greater resilience against clinical trial setbacks, making it a more attractive investment choice.
NASDAQ.COM
8.5
05-26NASDAQ.COM
Analysis of Gene Editing Industry Prospects
  • CRISPR Breakthrough: CRISPR Therapeutics received approval for Casgevy in 2023, a treatment for sickle cell disease and transfusion-dependent beta-thalassemia, which, despite currently low revenue, is expected to see significant commercial growth in the coming years.
  • Pipeline Advantage: The company's CTX310 is being developed to lower LDL cholesterol as a potential one-time treatment option, which could provide a more convenient choice in cardiovascular disease management, thereby enhancing its competitive position in the market.
  • Beam Innovation: Beam Therapeutics focuses on base editing technology and, while it currently has no products on the market, its Risto-cel candidate has shown strong results in clinical trials, with plans to submit a regulatory application by year-end, potentially driving its stock price higher.
  • Financial Comparison: As of the end of Q1, CRISPR Therapeutics had $2.4 billion in cash and marketable securities compared to Beam Therapeutics' $1.2 billion, indicating stronger financial stability that provides better resilience against clinical trial setbacks.
Fool
8.5
05-11Fool
CRISPR Therapeutics Shows Promising Upside Potential
  • Strong Stock Performance: CRISPR Therapeutics' shares have surged 56% over the past year, significantly outperforming the S&P 500's 30% gain, indicating robust market confidence in its growth prospects.
  • Optimistic Analyst Targets: According to Yahoo! Finance, CRISPR's average price target is $82.55, suggesting nearly 51% upside from current levels, while Piper Sandler's analyst has set a target of $110, indicating the stock could potentially double in the next 12 months.
  • Catalysts from Clinical Trials: The ongoing development of the anticoagulant CTX611 could yield crucial clinical trial data in the coming months, targeting a $20 billion market, and positive results could significantly boost the stock price.
  • Market Expansion Potential: The Casgevy drug, developed in collaboration with Vertex Pharmaceuticals, has yet to generate significant sales despite its 2023 approval due to its complex administration and high cost; however, the recent request for approval for children aged 5 to 11 could greatly expand its market potential, with annual revenues expected to exceed $1 billion in the coming years.
Wall Street analysts forecast VRTX stock price to rise
22 Analyst Rating
Wall Street analysts forecast VRTX stock price to rise
17 Buy
5 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Current: 0.000
sliders
Low
414.00
Averages
515.88
High
604.00
Truist
NULL
to
Buy
initiated
$525 -> $542
AI Analysis
2026-05-27
New
Reason
Truist
Price Target
$525 -> $542
AI Analysis
2026-05-27
New
initiated
NULL
to
Buy
Reason
Truist assumed coverage of Vertex Pharmaceuticals with a Buy rating and price target of $542, up from $525. The firm believes Vertex's emerging kidney franchise can grow into blockbuster assets and further diversify the company's product portfolio.
Barclays
NULL -> Overweight
maintain
$607 -> $615
2026-05-06
Reason
Barclays
Price Target
$607 -> $615
2026-05-06
maintain
NULL -> Overweight
Reason
Barclays raised the firm's price target on Vertex Pharmaceuticals to $615 from $607 and keeps an Overweight rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VRTX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 22.99, compared to its 5-year average forward P/E of 186.91. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
186.91
Current PE
22.99
Overvalued PE
780.92
Undervalued PE
-407.09

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
23.15
Current EV/EBITDA
18.99
Overvalued EV/EBITDA
47.08
Undervalued EV/EBITDA
-0.78

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.67
Current PS
7.78
Overvalued PS
10.12
Undervalued PS
7.21

Financials

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Whales Holding VRTX

P
ProFund Advisors LLC
Holding
VRTX
+28.95%
3M Return
S
Security Investors, LLC
Holding
VRTX
+24.30%
3M Return
B
Bluebox Asset Management Uk Ltd.
Holding
VRTX
+24.26%
3M Return
N
NEOS Investment Management, LLC
Holding
VRTX
+21.12%
3M Return
H
Hudson Bay Capital Management LP
Holding
VRTX
+20.71%
3M Return
J
Jennison Associates LLC
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+20.24%
3M Return

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Frequently Asked Questions

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?

The current price of VRTX is 447.54 USD — it has decreased -0.1

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).

What is the price predicton of VRTX Stock?

Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is515.88 USD with a low forecast of 414.00 USD and a high forecast of 604.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

Vertex Pharmaceuticals Inc revenue for the last quarter amounts to 2.99B USD, increased 7.82

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

Vertex Pharmaceuticals Inc. EPS for the last quarter amounts to 4.02 USD, increased 61.45

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?

Vertex Pharmaceuticals Inc (VRTX) has 6400 emplpoyees as of June 01 2026.

What is Vertex Pharmaceuticals Inc (VRTX) market cap?

Today VRTX has the market capitalization of 113.59B USD.