
Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
434.980
Open
429.970
VWAP
432.45
Vol
909.34K
Mkt Cap
110.32B
Low
428.510
Amount
393.25M
EV/EBITDA(TTM)
23.93
Total Shares
258.05M
EV
105.57B
EV/OCF(TTM)
--
P/S(TTM)
10.15
Vertex Pharmaceuticals Incorporated is a global biotechnology company. The Company is focused on investing in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has four approved medicines that treat the underlying cause of cystic fibrosis (CF), and one approved therapy that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT). Its pipeline includes clinical-stage programs in CF, SCD, TDT, acute and neuropathic pain, APOL1-mediated kidney disease, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency. Its marketed medicines are TRIKAFTA/KAFTRIO, SYMDEKO/SYMKEVI (tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor) and KALYDECO (ivacaftor). It is developing non-autologous (allogeneic) fully differentiated, stem-cell derived islet cell therapies designed to replace insulin-producing islet cells that are destroyed in people with T1D.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q4
FY2025Q3
FY2025Q2
3.22B
+10.47%
4.971
+24.89%
3.04B
+9.83%
4.596
+4.94%
2.91B
+9.83%
4.289
-133.43%
Estimates Revision
The market is revising Upward the revenue expectations for Vertex Pharmaceuticals Incorporated (VRTX) for FY2025, with the revenue forecasts being adjusted by 1.08% over the past three months. During the same period, the stock price has changed by -8.29%.
Revenue Estimates for FY2025
Revise Upward

+1.08%
In Past 3 Month
EPS Estimates for FY2025
Revise Upward

+9.54%
In Past 3 Month
Stock Price
Go Down

-8.29%
In Past 3 Month
27 Analyst Rating

16.54% Upside
Wall Street analysts forecast VRTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VRTX is 502.27 USD with a low forecast of 320.00 USD and a high forecast of 591.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
16 Buy
10 Hold
1 Sell
Moderate Buy

16.54% Upside
Current: 431.000

Low
320.00
Averages
502.27
High
591.00

16.54% Upside
Current: 431.000

Low
320.00
Averages
502.27
High
591.00
Cantor Fitzgerald
Carter Gould
Buy
Initiates
$535
2025-04-22
Reason
Cantor Fitzgerald
Carter Gould
Price Target
$535
2025-04-22
Initiates
Buy
Reason
Cantor Fitzgerald assumed coverage of Vertex Pharmaceuticals with an Overweight rating and $535 price target.
RBC Capital
Brian Abrahams
Hold
Maintains
$408 → $420
2025-04-01
Reason
RBC Capital
Brian Abrahams
Price Target
$408 → $420
2025-04-01
Maintains
Hold
Reason
RBC Capital analyst Brian Abrahams believes the resignation of the head of the FDA's Center for Biologics Evaluation and Research, Dr. Peter Marks, is "not good for the biotech industry even beyond vaccines." Marks had been a key advocate for more flexible, efficient approval processes for drugs, particularly those for orphan diseases such as gene therapies, the analyst tells investors in a research note. Additionally, the news highlights risk of further attrition among leaders and personnel at the FDA potentially frustrated with Robert F. Kennedy Jr.'s "lack of expertise/experience, which could slow engagement with drugmakers and drug review processes," contends RBC. The firm expects some weakness for biotech stocks "as uncertainty continues to be perpetuated." RBC believes the companies in its coverage that could see the greatest impact include Sarepta (SPRT), Legend Biotech (LEGN), Gilead (GILD), Regeneron (REGN), Vertex Pharmaceuticals (VRTX), PTC Therapeutics (PTCT), Galapagos (GLPG), Regenxbio (RGNX), Avidity Biosciences (RNA), Dyne Therapeutics (DYN), Moderna (MRNA), Karyopharm (KPTI), MeiraGTx (MGTX), and Pacira (PCRX).
B of A Securities
Ying Huang
Strong Buy
Maintains
$555 → $567
2025-03-31
Reason
B of A Securities
Ying Huang
Price Target
$555 → $567
2025-03-31
Maintains
Strong Buy
Reason
RBC Capital
Brian Abrahams
Hold
Maintains
$407 → $408
2025-02-20
Reason
RBC Capital
Brian Abrahams
Price Target
$407 → $408
2025-02-20
Maintains
Hold
Reason
Canaccord Genuity
Whitney Ijem
Strong Sell
to
Hold
Upgrades
$408 → $424
2025-02-12
Reason
Canaccord Genuity
Whitney Ijem
Price Target
$408 → $424
2025-02-12
Upgrades
Strong Sell
to
Hold
Reason
Canaccord upgraded Vertex Pharmaceuticals to Hold from Sell with a price target of $424, up from $408.
Needham
Joseph Stringer
Hold
Reiterates
n/a
2025-02-11
Reason
Needham
Joseph Stringer
Price Target
n/a
2025-02-11
Reiterates
Hold
Reason
See All Ratings
Valuation Metrics
The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX.O) is 22.77, compared to its 5-year average forward P/E of 185.98. For a more detailed relative valuation and DCF analysis to assess Vertex Pharmaceuticals Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
185.98
Current PE
22.77
Overvalued PE
777.96
Undervalued PE
-405.99
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
22.48
Current EV/EBITDA
16.95
Overvalued EV/EBITDA
46.53
Undervalued EV/EBITDA
-1.56
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

Fair
5Y Average PS
8.91
Current PS
9.09
Overvalued PS
10.63
Undervalued PS
7.19
Financials
Annual
Quarterly
FY2025Q1
YoY :
+2.96%
2.77B
Total Revenue
FY2025Q1
YoY :
-15.22%
1.03B
Operating Profit
FY2025Q1
YoY :
-41.22%
646.30M
Net Income after Tax
FY2025Q1
YoY :
-40.86%
2.49
EPS - Diluted
FY2025Q1
YoY :
-26.46%
778.20M
Free Cash Flow
FY2025Q1
YoY :
-0.42%
86.90
Gross Profit Margin - %
FY2025Q1
YoY :
-133.17%
-11.33
FCF Margin - %
FY2025Q1
YoY :
-42.92%
23.33
Net Margin - %
FY2025Q1
YoY :
-124.89%
-5.98
ROIC
Trading Trends
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
7.1M
USD
5
3-6
Months
7.2M
USD
11
6-9
Months
461.2K
USD
1
0-12
Months
20.7M
USD
11
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds areBuying! The buying amount has increased 1727.96% over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
128.3K
Volume
8
6-9
Months
0.0
Volume
0
0-12
Months
392.1K
Volume
22
Bought
0-3
0
0.0
Volume
Months
3-6
2
1.4M
Volume
Months
6-9
0
0.0
Volume
Months
0-12
10
78.0K
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
8.0K
USD
1
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
2
65.0K
USD
Months
6-9
1
8.0K
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
7.1M
USD
5
3-6
Months
7.2M
USD
11
6-9
Months
461.2K
USD
1
0-12
Months
20.7M
USD
11
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
VRTX News & Events
Events Timeline
2025-05-05 (ET)
2025-05-05
16:04:41
Vertex Pharmaceuticals narrows FY25 revenue to $11.85B-$12.0B, consensus $12.0B

2025-05-05
16:03:17
Vertex Pharmaceuticals reports Q1 EPS $2.49, consensus $4.29

2025-05-05
13:08:38
Notable companies reporting after market close

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News
9.5
05-07NASDAQ.COMPinnedWhy Vertex Pharmaceuticals Stock Is a Screaming Buy on the Dip
9.5
05-06BenzingaPinnedWhy Did Vertex Pharmaceuticals Stock Fall On Tuesday?
3.0
09:00 AMNASDAQ.COM4 No-Brainer Stocks to Buy Right Now
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FAQ

What is Vertex Pharmaceuticals Inc (VRTX) stock price today?
The current price of VRTX is 431 USD — it has increased 0.33 % in the last trading day.

What is Vertex Pharmaceuticals Inc (VRTX)'s business?

What is the price predicton of VRTX Stock?

What is Vertex Pharmaceuticals Inc (VRTX)'s revenue for the last quarter?

What is Vertex Pharmaceuticals Inc (VRTX)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for Vertex Pharmaceuticals Inc (VRTX)'s fundamentals?

How many employees does Vertex Pharmaceuticals Inc (VRTX). have?
