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TYRA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
33.120
Open
32.990
VWAP
32.56
Vol
50.13K
Mkt Cap
1.97B
Low
32.250
Amount
1.63M
EV/EBITDA(TTM)
--
Total Shares
59.47M
EV
1.59B
EV/OCF(TTM)
--
P/S(TTM)
--
Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing precision medicines that target large opportunities in FGFR biology. Its in-house precision medicine platform, SNAP, enables precise drug design through iterative molecular SNAPshots that help predict genetic alterations to cause acquired resistance to existing therapies. It has a differentiated pipeline with three product candidates in clinical development in targeted oncology and genetically defined conditions. Its lead precision medicine stemming from SNAP, TYRA-300, is a potential selective FGFR3 inhibitor that is designed to avoid the toxicities associated with inhibition of FGFR1, FGFR2 and FGFR4, while being agnostic for the FGFR3 gatekeeper mutations. It is also developing TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in the SURF201 study for metastatic intrahepatic cholangiocarcinoma, and TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers.
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Events Timeline

(ET)
2026-05-13
08:10:00
TYRA Reports $383.5M in Cash and Securities, Advancing Drug Development
select
2026-04-25 (ET)
2026-04-25
19:10:00
Lyft Short Interest Rises to 25.7%
select
2026-03-02 (ET)
2026-03-02
16:30:00
TYRA CEO Emphasizes FGFR3 Importance, Plans $256M Investment
select
2026-02-27 (ET)
2026-02-27
15:50:00
Lenz Therapeutics Short Interest Rises to 44%
select

News

Fool
6.5
05-17Fool
HighVista Strategies Increases Stake in Tyra Biosciences
  • Stake Increase: On May 15, 2026, HighVista Strategies disclosed the purchase of 96,218 shares of Tyra Biosciences, valued at approximately $3.11 million, indicating strong confidence in the company's future prospects.
  • Market Value Growth: The value of Tyra's position increased by $4.11 million at quarter-end due to both the additional shares acquired and stock price appreciation, reflecting robust performance and market recognition in the biopharmaceutical sector.
  • Stock Performance: As of May 14, 2026, Tyra's shares were priced at $36.51, representing a 280% increase over the past year, significantly outperforming the S&P 500 by 250 percentage points, showcasing investor optimism regarding potential clinical catalysts.
  • Financial Position: Tyra ended the first quarter with approximately $383.5 million in cash and cash equivalents, which management indicates should fund operations into the second half of 2028, enhancing its financial stability for upcoming clinical trials.
seekingalpha
9.5
05-13seekingalpha
Tyra Biosciences Reports Q1 Loss and Cash Position
  • Financial Performance: Tyra Biosciences reported a GAAP EPS of -$0.64 for Q1 2026, indicating ongoing challenges in profitability and reflecting persistent financial pressure on the company.
  • Cash Reserves: As of March 31, 2026, Tyra had $383.5 million in cash, cash equivalents, and short-term investments, which are expected to support the company's operational plans into the second half of 2028, ensuring its continued viability.
  • Rising Administrative Expenses: General and administrative expenses for Q1 2026 were $8.5 million, up from $6.9 million in the same period of 2025, primarily driven by increased compensation and personnel costs due to headcount growth, highlighting cost pressures during the company's expansion.
  • Widening Net Loss: The net loss for the first quarter was $39.3 million, compared to $28.1 million for the same period in 2025, indicating that the company still faces significant challenges in improving its financial health.
Fool
8.5
03-20Fool
Boone Capital Acquires New Stake in Tyra Biosciences
  • New Investment Disclosure: On February 17, 2026, Boone Capital Management disclosed its position in Tyra Biosciences, acquiring 398,482 shares worth $10.48 million, reflecting confidence in the company's growth potential.
  • Asset Management Proportion: The newly acquired shares represent 3.3% of Boone Capital's 13F reportable AUM as of December 31, 2025, indicating the firm's significant focus on Tyra within its investment portfolio.
  • Stock Performance: As of last Friday, Tyra's shares were priced at $38.67, having surged 253% over the past year, significantly outperforming the S&P 500's 16% increase during the same period, showcasing strong market optimism.
  • Financial Status Analysis: Despite a net loss nearing $120 million over the past year, Tyra maintains approximately $256 million in cash and investments, sufficient to fund operations into 2027, highlighting its ongoing development potential in the biotech sector.
NASDAQ.COM
8.5
03-20NASDAQ.COM
Boone Capital Acquires 398,482 Shares of Tyra Biosciences
  • New Investment Disclosure: Boone Capital disclosed the acquisition of 398,482 shares of Tyra Biosciences in Q4 2026, totaling $10.48 million, indicating a strategic interest in the biotech sector despite this position not being among the fund's top five holdings.
  • Financial Condition Analysis: Tyra Biosciences focuses on precision therapies for cancer and rare diseases, and while the company reported a net loss of approximately $120 million for the year, its $256 million in cash and investments is sufficient to fund operations into 2027, showcasing financial stability.
  • Clinical Strategy Focus: Tyra is narrowing its focus around a defined clinical strategy with three Phase 2 programs targeting FGFR3 biology, demonstrating discipline and foresight in the biotech field despite facing significant losses.
  • Market Performance Review: Since the end of last quarter, Tyra's shares have climbed about 47%, suggesting Boone Capital's investment may have already paid off, although the analyst team did not include Tyra in their current list of top investment stocks.
seekingalpha
9.5
03-02seekingalpha
Tyra Biosciences Q4 Earnings Report Analysis
  • Disappointing Earnings: Tyra Biosciences reported a Q4 GAAP EPS of -$0.57, missing expectations by $0.04, indicating ongoing challenges in profitability that could undermine investor confidence.
  • Net Loss Reported: The company recorded a net loss of $33.8 million, reflecting high costs in R&D and operations, which may lead to increased future financing needs and impact shareholder returns.
  • Cash Position: As of the end of the reporting period, Tyra Biosciences held $256 million in cash, cash equivalents, and marketable securities, providing a solid liquidity position, yet ongoing losses may restrict future investment and expansion capabilities.
  • Market Reaction Outlook: Given the earnings miss, investors may adopt a cautious stance towards Tyra Biosciences' future performance, potentially leading to stock price volatility and a decline in market confidence.
PRnewswire
8.5
03-02PRnewswire
Tyra Biosciences Launches 'Dabogratinib 3x3' Strategy for Blockbuster Indications
  • New Strategy Launch: Tyra Biosciences has unveiled its 'dabogratinib 3x3' strategy, aiming to conduct three late-stage clinical studies in low-grade upper tract urothelial carcinoma (LG-UTUC), intermediate-risk non-muscle invasive bladder cancer (IR NMIBC), and achondroplasia (ACH), demonstrating the company's strategic focus in precision medicine.
  • Clinical Data Progress: Interim Phase 2 data readouts for SURF302 are expected by the end of 1H 2026, with BEACH301 scheduled for 2H 2026, indicating Tyra's proactive advancement in clinical trials that may lay the groundwork for future regulatory submissions.
  • Strong Financial Position: As of Q4 2025, Tyra reported cash, cash equivalents, and marketable securities totaling $256 million, providing a runway through at least 2027, showcasing its financial resilience in supporting R&D and market expansion.
  • Significant Market Potential: By focusing on selective FGFR3 inhibition, Tyra aims to address high unmet medical needs while creating substantial long-term value, underscoring its strategic importance and competitive edge in the biotechnology sector.
Wall Street analysts forecast TYRA stock price to rise
5 Analyst Rating
Wall Street analysts forecast TYRA stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
33.75
High
37.00
Current: 0.000
sliders
Low
30.00
Averages
33.75
High
37.00
Wolfe Research
Peer Perform
initiated
AI Analysis
2026-05-19
Reason
Wolfe Research
Price Target
AI Analysis
2026-05-19
initiated
Peer Perform
Reason
Wolfe Research initiated coverage of Tyra Biosciences with a Peer Perform rating an no price target. Tyra has dabogratinib in development for bladder cancer and achondroplasia, notes the analyst, who sees the drug as likely to \"achieve the CR bar for LR IR NMIBC,\" but is \"on the fence\" until seeing safety de-risking. The pipeline supports the long-term thesis, though current levels limit near-term upside, the analyst added.
Guggenheim
Buy
initiated
$54
2026-04-15
Reason
Guggenheim
Price Target
$54
2026-04-15
initiated
Buy
Reason
Guggenheim last night initiated coverage of Tyra Biosciences with a Buy rating and $54 price target. The firm says the company "has the right drug" to test three clinical hypotheses across three disparate patient populations, "where success in any one could generate significant upside." The company's dabogratinib "could find its home at lower doses in multiple diseases," the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for TYRA
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Valuation Metrics

The current forward P/E ratio for Tyra Biosciences Inc (TYRA.O) is 0.00, compared to its 5-year average forward P/E of -8.72. For a more detailed relative valuation and DCF analysis to assess Tyra Biosciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-8.72
Current PE
0.00
Overvalued PE
-4.25
Undervalued PE
-13.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.45
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
12.33
Undervalued EV/EBITDA
-19.24

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2830.91
Current PS
326684.59
Overvalued PS
33699.98
Undervalued PS
-28038.16

Financials

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Whales Holding TYRA

C
Commodore Capital LP
Holding
TYRA
+18.34%
3M Return
T
TCG Crossover Management, LLC
Holding
TYRA
+11.54%
3M Return
F
Farallon Capital Management, L.L.C.
Holding
TYRA
+11.08%
3M Return
L
Logos Global Management, L.P.
Holding
TYRA
+6.22%
3M Return
V
Vestal Point Capital, LP
Holding
TYRA
+5.45%
3M Return
B
BVF Partners L.P.
Holding
TYRA
+2.38%
3M Return

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Frequently Asked Questions

What is Tyra Biosciences Inc (TYRA) stock price today?

The current price of TYRA is 32.32 USD — it has decreased -1.1

What is Tyra Biosciences Inc (TYRA)'s business?

Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing precision medicines that target large opportunities in FGFR biology. Its in-house precision medicine platform, SNAP, enables precise drug design through iterative molecular SNAPshots that help predict genetic alterations to cause acquired resistance to existing therapies. It has a differentiated pipeline with three product candidates in clinical development in targeted oncology and genetically defined conditions. Its lead precision medicine stemming from SNAP, TYRA-300, is a potential selective FGFR3 inhibitor that is designed to avoid the toxicities associated with inhibition of FGFR1, FGFR2 and FGFR4, while being agnostic for the FGFR3 gatekeeper mutations. It is also developing TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in the SURF201 study for metastatic intrahepatic cholangiocarcinoma, and TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers.

What is the price predicton of TYRA Stock?

Wall Street analysts forecast TYRA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TYRA is33.75 USD with a low forecast of 30.00 USD and a high forecast of 37.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Tyra Biosciences Inc (TYRA)'s revenue for the last quarter?

Tyra Biosciences Inc revenue for the last quarter amounts to -42.00M USD, increased 31.86

What is Tyra Biosciences Inc (TYRA)'s earnings per share (EPS) for the last quarter?

Tyra Biosciences Inc. EPS for the last quarter amounts to -32659000.00 USD, increased 28.22

How many employees does Tyra Biosciences Inc (TYRA). have?

Tyra Biosciences Inc (TYRA) has 87 emplpoyees as of May 29 2026.

What is Tyra Biosciences Inc (TYRA) market cap?

Today TYRA has the market capitalization of 1.97B USD.