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TYRA Should I Buy

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Intellectia

Should You Buy Tyra Biosciences Inc (TYRA) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Buy
Latest Price
36.290
1 Day change
-4.58%
52 Week Range
39.150
Analysis Updated At
2026/03/27
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Tyra Biosciences Inc (TYRA) presents a compelling long-term investment opportunity for a beginner investor with $50,000-$100,000 available. Despite a slight pre-market dip, the stock has strong analyst support, significant upside potential due to its FGFR3 inhibitor pipeline, and a robust cash position to fund operations into 2027. The technical indicators and options data suggest a neutral to slightly bullish sentiment, making this a good buy for long-term growth.

Technical Analysis

The stock shows bullish moving averages (SMA_5 > SMA_20 > SMA_200), indicating a positive trend. The MACD histogram is negative but contracting, suggesting potential stabilization. RSI is neutral at 67.976, and the stock is trading near its resistance level of 38.754, with support at 36.787. Overall, the technical indicators lean slightly bullish.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate a bullish sentiment in the options market, with significantly higher call volume compared to put volume.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
7

Positive Catalysts

  • Strong analyst support with multiple Overweight/Outperform ratings and price targets raised to as high as $59.

  • Boone Capital Management's recent acquisition of 398,482 shares reflects institutional confidence.

  • The company's focus on three high-value Phase 2 clinical programs targeting FGFR3 biology, with significant market potential in oncology and growth disorders.

  • Robust cash position of $256 million to fund operations into 2027.

Neutral/Negative Catalysts

  • The company reported a net loss of $120 million over the past year, though this is typical for biotech firms in the development phase.

  • The stock has already increased 47% since last quarter, which might limit short-term upside.

Financial Performance

In Q4 2025, the company reported a net income loss of -$33.83 million, improving by 32.31% YoY. EPS also improved by 32.56% YoY to -0.57. While revenue remains at $0, the company is in a development phase with a strong cash position of $256 million to fund operations into 2027.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are highly bullish on TYRA, with multiple firms raising price targets and initiating Overweight/Outperform ratings. The highest price target is $59.62, reflecting significant upside potential from the current price of $37.6. Analysts highlight the company's FGFR3 inhibitor pipeline as a key growth driver, with blockbuster potential in oncology and growth disorders.

Wall Street analysts forecast TYRA stock price to fall
5 Analyst Rating
Wall Street analysts forecast TYRA stock price to fall
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 38.030
sliders
Low
30
Averages
33.75
High
37
Current: 38.030
sliders
Low
30
Averages
33.75
High
37
Piper Sandler
Piper Sandler
Overweight
upgrade
$42 -> $56
AI Analysis
2026-03-20
Reason
Piper Sandler
Piper Sandler
Price Target
$42 -> $56
AI Analysis
2026-03-20
upgrade
Overweight
Reason
Piper Sandler raised the firm's price target on Tyra Biosciences to $56 from $42 and keeps an Overweight rating on the shares heading into the stock's two key 2026 data events for dabogratinib. First up will be initial three months CR data in IR-NMIBC, followed by six months AHV data from the safety sentinel cohort in achondroplasia. The firm believes the efficacy bars are clearly defined and achievable. Piper knows from erdafitinib and infigratinib that FGFR3 inhibition works in these indications, and believes these readouts will show that dabo's selectivity for FGFR3 means it can hit the efficacy bars safely, with a clean safety profile that allows for chronic dosing.
Cantor Fitzgerald
Overweight
initiated
2026-02-24
Reason
Cantor Fitzgerald
Price Target
2026-02-24
initiated
Overweight
Reason
Cantor Fitzgerald initiated coverage of Tyra Biosciences with an Overweight rating. A constructive stance on Tyra shares is driven by three high-conviction Phase 2 clinical readouts for dabogratinib, a selective small-molecule FGFR3 inhibitor currently in development, the analyst tells investors in a research note.
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