$
22.540
-1.15(-4.854%)1D
  • Overview
  • Forecast
  • Valuation
  • Earnings
Line
Line
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Candle
Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
23.935
Open
23.300
VWAP
22.73
Vol
474.19K
Mkt Cap
662.24M
Low
22.400
Amount
10.78M
EV/EBITDA(TTM)
--
Total Shares
27.32M
EV
356.09M
EV/OCF(TTM)
--
P/S(TTM)
6.21
AnaptysBio, Inc. is a clinical-stage biotechnology company. The Company is focused on delivering immunology therapeutics for autoimmune and inflammatory diseases. The Company’s lead program, Rosnilimab, is a depleter and agonist targeting PD-1+ T cells, is in a Phase IIb trial for the treatment of rheumatoid arthritis and in a Phase II trial for the treatment of ulcerative colitis. The Company’s pipeline also includes ANB033, a CD122 antagonist, and ANB101, a blood dendritic cell antigen 2 (BDCA2) modulator, in Phase I trials. It has also discovered multiple therapeutic antibodies licensed to GSK in a financial collaboration for immuno-oncology, including a PD-1 antagonist (Jemperli (dostarlimab-gxly)) and a TIM-3 antagonist (cobolimab, GSK4069889). Rosnilimab is an IgG1 antibody that directly targets PD-1+ T cells, resulting in their depletion or agonism, impacting pathogenic drivers of autoimmune and inflammatory diseases.
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Market Estimates

Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q2
FY2025Q3
FY2025Q4
11.68M
+6.5%
-1.546
-9.58%
11.76M
-60.81%
-1.534
+34.56%
28.32M
-34.32%
-1.161
+61.23%
Estimates Revision
The market is revising Upward the revenue expectations for AnaptysBio, Inc. (ANAB) for FY2025, with the revenue forecasts being adjusted by 24.1% over the past three months. During the same period, the stock price has changed by 14.53%.
Revenue Estimates for FY2025
Revise Upward
up Image
+24.1%
In Past 3 Month
EPS Estimates for FY2025
Revise Downward
down Image
-2.52%
In Past 3 Month
Stock Price
Go Up
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+14.53%
In Past 3 Month
11 Analyst Rating
up Image
125.64% Upside
Wall Street analysts forecast ANAB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ANAB is 50.86 USD with a low forecast of 25.00 USD and a high forecast of 90.00  USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
10 Buy
1 Hold
0 Sell
Strong Buy
up Image
125.64% Upside
Current: 22.540
sliders
Low
25.00
Averages
50.86
High
90.00
JPMorgan
Overweight
maintain
2025-06-11
Reason
JPMorgan says AnaptysBio shares at current levels are undervalued on the clinical and strategic potential of rosnilimab in rheumatoid arthritis alone. Looking to the balance of the year, the firm expects an increasing focus on the potential of the asset in ulcerative colitis, given the anticipated Q4 Phase 2 data. JPMorgan does not sense there are any Street expectations for the ulcerative colitis Phase 2 readout. While the company did not provide more granular details on timing, AnaptysBio noted a clear line of sight on enrollment completion, so the timelines are not at risk, the analyst tells investors in a research note. JPMorgan keeps an Overweight rating on AnaptysBio.
H.C. Wainwright
H.C. Wainwright
Neutral -> Buy
upgrade
$38
2025-06-04
Reason
H.C. Wainwright upgraded AnaptysBio to Buy from Neutral with a $38 price target after the company announced week 28 data from the Phase 2 rheumatoid arthritis trial which met its primary endpoint. The firm says that given the data "showcase a positive holistic story" for rosnilimab in rheumatoid arthritis, it is increasingly positive on upcoming ulcerative colitis data. AnaptysBio's week 28 data compare favorably with competitor datasets, such as JAK inhibitors, contends H.C. Wainwright.
Guggenheim
NULL -> Buy
maintain
$54 -> $90
2025-05-28
Reason
Guggenheim raised the firm's price target on AnaptysBio (ANAB) to $90 from $54 and keeps a Buy rating on the shares. The firm is "encouraged" by the company's ongoing clinical developments and strong financial position and believes the stock is trading at a significant discount, says the analyst, who updated the firm's model to reflect GSK's (GSK) Jemperli royalties.
JP Morgan
Anupam Rama
Buy
Maintains
$36 → $42
2025-03-05
Reason
JPMorgan raised the firm's price target on AnaptysBio to $42 from $36 and keeps an Overweight rating on the shares. The firm updated models in the Smid-cap biotechnology group.
HC Wainwright & Co.
Emily Bodnar
Hold
Reiterates
$22
2025-03-04
Reason
Wells Fargo
Derek Archila
Buy
Maintains
$40 → $51
2025-02-13
Reason

Valuation Metrics

The current forward P/E ratio for AnaptysBio Inc (ANAB.O) is -4.36, compared to its 5-year average forward P/E of -4.22. For a more detailed relative valuation and DCF analysis to assess AnaptysBio Inc 's fair value, click here.

Forward PE

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.22
Current PE
-4.36
Overvalued PE
2.59
Undervalued PE
-11.03

Forward EV/EBITDA

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.36
Current EV/EBITDA
-6.70
Overvalued EV/EBITDA
1.63
Undervalued EV/EBITDA
-6.35

Forward PS

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
Fair
5Y Average PS
29.39
Current PS
11.53
Overvalued PS
54.27
Undervalued PS
4.50

Financials

Annual
Quarterly
FY2025Q2
YoY :
+102.93%
22.26M
Total Revenue
FY2025Q2
YoY :
-35.10%
-26.17M
Operating Profit
FY2025Q2
YoY :
-17.21%
-38.63M
Net Income after Tax
FY2025Q2
YoY :
-21.64%
-1.34
EPS - Diluted
FY2025Q2
YoY :
+88.63%
-40.28M
Free Cash Flow
FY2025Q2
YoY :
-100.00%
N/A
Gross Profit Margin - %
FY2025Q2
YoY :
-75.61%
-103.99
FCF Margin - %
FY2025Q2
YoY :
-100.00%
N/A
Net Margin - %

Trading Trends

Insider
Insiders areSelling! The selling amount has increased 241.21% over the last month.
Sold
0-3
Months
637.7K
USD
3
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
1.4M
USD
6
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
3
1.1M
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
812.0K
Volume
2
6-9
Months
714.7K
Volume
2
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
3
4.8M
Volume
Months
6-9
6
5.0M
Volume
Months
0-12
1
274.0K
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months

ANAB News & Events

Events Timeline

2025-06-04 (ET)
2025-06-04
12:58:14
AnaptysBio's rosnilimab demonstrates safety in Phase 2b trial, says Leerink
select
2025-06-03 (ET)
2025-06-03
16:29:24
AnaptysBio announces investigational rosnilimab data
select
2025-05-05 (ET)
2025-05-05
17:02:54
AnaptysBio reports Q1 EPS ($1.28), consensus ($1.46)
select
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News

9.0
06-04SeekingAlpha
J&J sends AnaptysBio lower with mid-stage trial data for anti-inflammatory agent
4.0
06-04Benzinga
This Snowflake Analyst Turns Bullish; Here Are Top 5 Upgrades For Wednesday
9.0
06-04SeekingAlpha
Anaptys gains after updated data from mid-stage trial for arthritis therapy
Sign Up For More News

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The current price of ANAB is 22.54 USD — it has decreased -4.85 % in the last trading day.

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