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QURE Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
29.290
Open
29.280
VWAP
27.73
Vol
928.18K
Mkt Cap
1.84B
Low
26.870
Amount
25.74M
EV/EBITDA(TTM)
--
Total Shares
63.07M
EV
1.78B
EV/OCF(TTM)
--
P/S(TTM)
95.87
Uniqure NV is a company based in the Netherlands specialized in gene therapy. It seeks to develop one-time administered treatments with potentially curative results for patients suffering from genetic and other devastating diseases. It develops, both internally and through partnerships, a pipeline of gene therapies. It produces adeno-associated virus based, or AAV-based, gene therapies in its own facilities with a proprietary, commercial-scale, current good manufacturing practices, compliant, manufacturing process. AMT-061, the Company’s lead product candidate for patients with hemophilia B, is going through a dosing phase of a pivotal study. AMT-130, the product candidate for patients with Huntington’s disease is in Phase I/II clinical study.
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Events Timeline

(ET)
2026-05-12
16:20:00
Major Averages Finish Mixed as Semiconductor Stocks Pull Back
select
2026-05-12
10:50:00
Trump Plans to Reduce Beef Import Tariffs
select
2026-05-11 (ET)
2026-05-11
12:30:00
Trump Approves Firing of FDA Commissioner Makary
select
link
2026-05-11
10:20:00
Trump Plans to Fire FDA Commissioner, Biotech Stocks Affected
select
2026-05-08 (ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
select
2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
select
link
2026-05-05 (ET)
2026-05-05
07:40:00
uniQure Q1 Revenue $3.56M, Below Consensus $4.49M
select

News

stocktwits
7.0
05-12stocktwits
FDA Commissioner Resignation Triggers Stock Movements
  • Commissioner Resignation: Marty Makary's resignation from the FDA, following clashes with the Trump administration, has led to Kyle Diamantas stepping in as acting commissioner, potentially shifting FDA policy and its relationship with the pharmaceutical industry.
  • Positive Market Reaction: Following Makary's exit, shares of Replimune (REPL) and uniQure (QURE) surged by 7% and 5%, respectively, indicating market optimism regarding the new leadership and future regulatory approaches.
  • Strong Industry Backlash: Replimune faced significant criticism after the FDA rejected its melanoma therapy RP1, and Makary's departure may alter the regulatory landscape, impacting the company's strategic direction moving forward.
  • Investor Sentiment Shift: While REPL has fallen 49% over the past year, QURE has gained 120%, reflecting differing investor sentiments towards the future prospects of both companies, especially in light of potential FDA policy changes.
CNBC
5.0
05-12CNBC
FDA Commissioner Makary Resigns Amid Controversy
  • Makary Resignation: FDA Commissioner Marty Makary resigned on December 18, 2025, concluding a controversial tenure marked by criticism over the government's COVID-19 response and drug approval processes, which drew backlash from various stakeholders.
  • Acting Commissioner Appointment: President Trump announced that Kyle Diamantas will temporarily take over as acting commissioner, having previously served as the top food official at the FDA, and will need to navigate the complex drug approval landscape left by Makary.
  • Internal Turmoil Intensifies: Under Makary's leadership, staff morale at the FDA plummeted due to layoffs and departures, notably that of cancer regulator Richard Pazdur, leading to increased distrust in leadership and impacting the agency's stability.
  • Drug Approval Controversies: During Makary's tenure, the FDA rejected several rare disease treatments, raising concerns within the pharmaceutical industry, particularly as negotiations for the reauthorization of the Prescription Drug User Fee Act highlighted the industry's sensitivity to leadership changes at the FDA.
stocktwits
6.5
05-08stocktwits
FDA Leadership Shakeup May Impact Biotech Stocks
  • Stock Price Surge: Following reports of potential dismissal of FDA Commissioner Marty Makary, shares of Replimune (REPL) and uniQure (QURE) surged by 17% and 15% respectively, indicating market optimism regarding regulatory improvements under new leadership.
  • Industry Response: The pharmaceutical industry has expressed dissatisfaction with Makary's drug review policies, citing inconsistencies and overly restrictive processes that hinder innovative drug approvals, suggesting that new leadership could accelerate approval timelines and restore clearer regulatory guidance.
  • Potential Beneficiaries: Companies like Replimune and uniQure, which have publicly clashed with the FDA, are seen as potential beneficiaries of new leadership, with Replimune's melanoma therapy RP1 being rejected and uniQure's Huntington's disease gene therapy AMT-130 facing significant shifts in review policy.
  • Market Reaction: Despite REPL's stock falling approximately 50% over the past year, QURE's stock has risen by 124%, reflecting investor confidence in the future of the biotech sector and expectations for changes in FDA policies.
moomoo
7.0
05-08moomoo
ClearPoint Neuro and UniQure Stocks Surge Following WSJ Report on Trump's Potential Plan to Dismiss FDA Commissioner Marty Makary
  • Company Overview: ClearPoint Neuro and Uniqure are involved in the biotechnology sector, focusing on innovative solutions in neurotechnology.

  • Market Reaction: Shares of ClearPoint Neuro have seen a significant increase following reports from the Wall Street Journal regarding potential changes in leadership at the FDA.

  • Leadership Changes: The reports suggest that former President Trump is considering firing FDA Commissioner Marty Makary, which has implications for regulatory processes in the biotech industry.

  • Investor Sentiment: The news has sparked interest among investors, leading to a spike in ClearPoint Neuro's stock prices as market participants react to the potential shifts in FDA oversight.

seekingalpha
9.5
05-05seekingalpha
uniQure Q1 2026 Earnings Call Insights
  • Revenue Growth: uniQure reported revenue of $3.6 million for Q1 2026, a 125% increase from $1.6 million in the prior year, primarily driven by increased licensing revenue, indicating a strengthening market position and commercialization potential.
  • R&D Expense Adjustment: Research and development expenses were $29.2 million, down from $36.1 million a year ago, mainly due to reduced external spending and personnel costs, providing greater financial flexibility for future clinical trials.
  • Cash Flow Status: As of March 31, 2026, the company had $586.6 million in cash, cash equivalents, and investment securities, expected to fund operations into the second half of 2029, reflecting robust financial management.
  • Clinical Trial Progress: uniQure is preparing to submit a marketing authorization application for AMT-130 in the U.K. and plans to hold a Type B FDA meeting in Q2 to discuss new clinical study designs, laying the groundwork for future product launches.
seekingalpha
9.5
05-05seekingalpha
uniQure Q1 Earnings Beat Expectations Despite Revenue Miss
  • Earnings Highlights: uniQure reported a Q1 GAAP EPS of -$0.85, beating expectations by $0.01, indicating efforts in cost control, although overall financial performance still requires improvement.
  • Revenue Growth: The company generated $3.56M in revenue, a 126.8% year-over-year increase, but fell short of expectations by $1.71M, reflecting market demand fluctuations and sales challenges.
  • License Revenue Increase: The $2.0M increase in license revenue compared to the prior period suggests that the company's strategic focus on intellectual property is beginning to pay off, potentially laying the groundwork for future revenue growth.
  • Market Reaction: Despite mixed financial indicators, uniQure's stock rose following regulatory updates, indicating market optimism regarding the prospects of its gene therapy asset AMT-130.
Wall Street analysts forecast QURE stock price to rise
10 Analyst Rating
Wall Street analysts forecast QURE stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
33.00
Averages
49.88
High
70.00
Current: 0.000
sliders
Low
33.00
Averages
49.88
High
70.00
H.C. Wainwright
Patrick Trucchio
Buy
downgrade
$70 -> $50
AI Analysis
2026-05-06
Reason
H.C. Wainwright
Patrick Trucchio
Price Target
$70 -> $50
AI Analysis
2026-05-06
downgrade
Buy
Reason
H.C. Wainwright analyst Patrick Trucchio lowered the firm's price target on uniQure to $50 from $70 and keeps a Buy rating on the shares after the company reported Q1 results and provided updates across its gene therapy pipeline. AMT-130 timing risk has increased in the U.S., but the U.K. path "now provides a credible route to first approval" and the firm continues to view AMT-130 as having "the strongest clinical dataset generated" in Huntington's disease, the analyst tells investors.
Stifel
Paul Matteis
Buy
maintain
$14 -> $28
2026-05-05
Reason
Stifel
Paul Matteis
Price Target
$14 -> $28
2026-05-05
maintain
Buy
Reason
Stifel analyst Paul Matteis raised the firm's price target on uniQure to $28 from $14 and keeps a Buy rating on the shares. The firm reiterated its Buy view following the company's Q1 update, where the company remains on track to have a Type B meeting with the FDA in 2Q26. While the firm isn't expecting an imminent FDA 180, what will be interesting here is tot see how uniQure can try to preserve some optionality with the four-year data cut, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for QURE
Unlock Now

Valuation Metrics

The current forward P/E ratio for Uniqure NV (QURE.O) is 27.93, compared to its 5-year average forward P/E of -4.23. For a more detailed relative valuation and DCF analysis to assess Uniqure NV's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.23
Current PE
27.93
Overvalued PE
12.06
Undervalued PE
-20.52

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.03
Current EV/EBITDA
-2.07
Overvalued EV/EBITDA
0.18
Undervalued EV/EBITDA
-10.25

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
17.72
Current PS
28.34
Overvalued PS
38.60
Undervalued PS
-3.16

Financials

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Quarterly

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Uniqure NV
1.49B

Whales Holding QURE

A
Avoro Capital Advisors LLC
Holding
QURE
+18.32%
3M Return
S
Senvest Management, LLC
Holding
QURE
+16.81%
3M Return
S
Suvretta Capital Management, LLC
Holding
QURE
+16.07%
3M Return
N
Nantahala Capital Management, LLC
Holding
QURE
+11.06%
3M Return
S
Sofinnova Investment, Inc.
Holding
QURE
+3.50%
3M Return
R
RTW Investments, LP
Holding
QURE
+3.40%
3M Return

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Frequently Asked Questions

What is Uniqure NV (QURE) stock price today?

The current price of QURE is 27.03 USD — it has decreased -7.34

What is Uniqure NV (QURE)'s business?

Uniqure NV is a company based in the Netherlands specialized in gene therapy. It seeks to develop one-time administered treatments with potentially curative results for patients suffering from genetic and other devastating diseases. It develops, both internally and through partnerships, a pipeline of gene therapies. It produces adeno-associated virus based, or AAV-based, gene therapies in its own facilities with a proprietary, commercial-scale, current good manufacturing practices, compliant, manufacturing process. AMT-061, the Company’s lead product candidate for patients with hemophilia B, is going through a dosing phase of a pivotal study. AMT-130, the product candidate for patients with Huntington’s disease is in Phase I/II clinical study.

What is the price predicton of QURE Stock?

Wall Street analysts forecast QURE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for QURE is49.88 USD with a low forecast of 33.00 USD and a high forecast of 70.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Uniqure NV (QURE)'s revenue for the last quarter?

Uniqure NV revenue for the last quarter amounts to 3.56M USD, increased 127.31

What is Uniqure NV (QURE)'s earnings per share (EPS) for the last quarter?

Uniqure NV. EPS for the last quarter amounts to -0.85 USD, increased 3.66

How many employees does Uniqure NV (QURE). have?

Uniqure NV (QURE) has 221 emplpoyees as of May 14 2026.

What is Uniqure NV (QURE) market cap?

Today QURE has the market capitalization of 1.84B USD.