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BCRX Overview

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ET
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ET
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Intellectia

Loading chart...

High
10.150
Open
9.800
VWAP
9.92
Vol
1.18M
Mkt Cap
2.43B
Low
9.680
Amount
11.67M
EV/EBITDA(TTM)
9.52
Total Shares
254.16M
EV
3.03B
EV/OCF(TTM)
9.69
P/S(TTM)
2.43
BioCryst Pharmaceuticals, Inc. is a biotechnology company focused on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. Its marketed products include oral, once-daily ORLADEYO for the prevention of HAE attacks and RAPIVAB (peramivir injection) for the treatment of acute uncomplicated influenza in the United States. Its other products and product candidates include BCX17725, navenibart, Avoralstat, STAR-0310, RAPIACTA (peramivir injection) and PERAMIFLU (peramivir injection). The RAPIVAB (peramivir injection) is approved in the United States for the treatment of acute uncomplicated influenza for patients six months and older. Peramivir injection is also approved in Canada (RAPIVAB), Australia (RAPIVAB), Japan (RAPIACTA), Taiwan (RAPIACTA), and Korea (PERAMIFLU). It has also obtained an early-stage program for atopic dermatitis (AD), STAR0310.
Show More

Events Timeline

(ET)
2026-06-29
07:30:00
BioCryst Announces Closure of Internal Discovery Programs by End of 2026
select
2026-06-25 (ET)
2026-06-25
09:01:00
Angion Biomedica Borrow Rate Increases to 183.97%
select
2026-06-12 (ET)
2026-06-12
07:30:00
BioCryst Announces New Clinical Data and Therapy for HAE
select
2026-05-06 (ET)
2026-05-06
08:00:00
BioCryst Reports Q1 Revenue of $156.41M
select
2026-05-06
08:00:00
Company Maintains FY26 ORLADEYO Revenue Outlook of $625M-$645M
select
2026-05-04 (ET)
2026-05-04
07:20:00
BioCryst Enters License Agreement with Neopharmed Gentili, Receives $70M Upfront
select
2026-04-06 (ET)
2026-04-06
07:10:00
BioCryst Appoints Sandeep Menon as Chief R&D Officer
select

News

Newsfilter
4.5
06-29Newsfilter
BioCryst Accelerates Rare Disease Pipeline Growth Through Strategic Shift
  • Strategic Shift: BioCryst announced the discontinuation of its internal discovery programs and the closure of its Birmingham, Alabama, Discovery Center of Excellence, prioritizing external innovation to build a sustainable rare disease pipeline in a more nimble and capital-efficient manner.
  • Clinical Trial Progress: Enrollment for the Phase 3 ALPHA-ORBIT study of navenibart has been completed, positioning it to potentially be the first hereditary angioedema therapy with both 3- and 6-month dosing, with efficacy data expected in Q3 2027.
  • Improved Financial Outlook: BioCryst has revised its 2026 non-GAAP operating expense guidance down from $450-$470 million to $420-$440 million, demonstrating the company's ability to control costs during its transition.
  • Product Launch Plans: The previously disclosed manufacturing delay of ORLADEYO oral pellets has been resolved, with the product expected to be available in early August 2026, further enhancing the company's competitive position in the rare disease market.
stocktwits
7.5
06-25stocktwits
BioCryst Pharmaceuticals Shares Surge Amid Positive Therapy Data
  • Strong Stock Performance: BioCryst Pharmaceuticals (BCRX) shares have surged for six consecutive trading days, gaining over 33% and reaching a 52-week high on Thursday, reflecting strong investor confidence in its future performance.
  • Market Sentiment Extremely Bullish: Data from Stocktwits indicates that retail sentiment for BCRX remains in the 'extremely bullish' zone, with message volumes surging 360% within a 24-hour period, suggesting investor anticipation for a breakout above key resistance levels.
  • Promising Orladeyo Therapy: Recent data from BioCryst shows that its Orladeyo therapy significantly reduced hereditary angioedema attacks in children aged 2 to 12, with medical care needs dropping from 22 to just 3, and projected revenue for Orladeyo in 2026 is expected to reach $625 million to $645 million, accounting for 97.7% to 98.4% of total revenue.
  • Advancement in Drug Development: BioCryst is also advancing a potential treatment for Netherton syndrome, with Phase 1 data expected by year-end, further enhancing the company's competitive position in the rare disease market.
NASDAQ.COM
8.0
06-24NASDAQ.COM
Bitdeer and BioCryst Options Trading Activity Surges
  • Surge in Bitdeer Options: Bitdeer Technologies Group (BTDR) has seen an options trading volume of 60,785 contracts today, equating to approximately 6.1 million shares, which represents about 49.9% of its average daily trading volume over the past month, indicating strong market interest in its future performance.
  • High Call Option Activity: Within BTDR, the $20 strike call option has been particularly active, with 30,291 contracts traded today, representing around 3.0 million shares, reflecting a strong bullish sentiment among investors regarding the stock's potential upside.
  • BioCryst Options Trading: BioCryst Pharmaceuticals Inc (BCRX) has recorded an options trading volume of 21,183 contracts today, translating to approximately 2.1 million shares, which is about 49.1% of its average daily trading volume over the past month, showcasing market interest in its growth prospects.
  • Active BCRX Call Options: For BCRX, the $15 strike call option has also seen significant activity, with 8,347 contracts traded today, representing approximately 834,700 shares, indicating investor optimism about the company's future performance.
NASDAQ.COM
9.0
06-12NASDAQ.COM
BioCryst Releases New Data on ORLADEYO and Navenibart
  • ORLADEYO Efficacy: In the APeX-P study, patients treated with ORLADEYO experienced only 0.169 hereditary angioedema (HAE) attacks per month, a significant reduction from 0.691 attacks on standard-of-care therapies, highlighting the drug's effectiveness in lowering attack frequency.
  • Standard Treatment Comparison: Over a 12-week observation period, patients on standard treatment averaged 22 HAE attacks, which dropped to just 3 attacks with ORLADEYO, indicating its potential to significantly improve patients' quality of life through long-term prevention of HAE attacks.
  • Navenibart Development Progress: BioCryst is developing Navenibart as a long-acting treatment, with preliminary data showing effective reduction of moderate to severe HAE attacks across various body mass index (BMI) and age groups, supporting its application in future clinical trials.
  • Clinical Trial Support: The Phase 1b/2 ALPHA-STAR trial results for Navenibart indicate reduced on-demand medication use among treated patients, with good drug tolerability, laying the groundwork for its upcoming Phase 3 ALPHA-ORBIT trial, which could offer new treatment options for HAE patients.
Yahoo Finance
9.5
06-06Yahoo Finance
BioCryst Reaffirms ORLADEYO Revenue Guidance Amid Navenibart Trial Progress
  • Revenue Guidance Reaffirmed: BioCryst reaffirms its 2023 ORLADEYO revenue guidance of $625 million to $645 million, with Q1 revenue at $148.3 million aligning with expectations, indicating strong patient demand and reimbursement trends that are expected to drive U.S. sales towards the $1 billion target.
  • Pediatric Launch Delayed: The pediatric launch of ORLADEYO was delayed due to a batch-specific manufacturing issue, which is deemed isolated and non-safety-related; early prescriptions have exceeded expectations, indicating strong market demand, and once available, this could positively impact sales.
  • Navenibart Trial Progress: BioCryst's navenibart Phase 3 trial is nearing completion of enrollment, with top-line data expected in Q3 next year and a BLA filing planned by the end of 2027, showcasing the company's ongoing R&D advancements in rare diseases.
  • Strong Financial Position: BioCryst reported a cash position of $330 million at the end of Q1, with expectations of profitability this year and increased profitability next year, reflecting robust development in both commercialization and R&D efforts.
seekingalpha
9.5
05-06seekingalpha
BioCryst Pharmaceuticals Q1 2026 Earnings Call Highlights
  • Strong Financial Performance: BioCryst reported ORLADEYO net revenue of $148.3 million for Q1 2026, aligning with expectations and reflecting a 21% year-over-year increase, indicating robust market demand and sustained revenue growth potential.
  • R&D Progress on Track: The pivotal ALPHA-ORBIT trial for navenibart has exceeded expectations, with approximately 145 patients expected to be enrolled by the end of next month, laying the groundwork for future regulatory submissions and enhancing the company's competitive position in the rare disease space.
  • Market Competition Management: Despite facing new competition, demand for new prescriptions among patients aged 12 and older remains stable, demonstrating continued trust in ORLADEYO from both physicians and patients, which is expected to drive further market share growth.
  • Supply Chain Challenges: Although a manufacturing issue for pediatric formulations has been identified that will delay initial product fulfillment, management has stated that this delay will not impact the revenue guidance for 2026, reflecting the company's confidence in future performance.
Wall Street analysts forecast BCRX stock price to rise
11 Analyst Rating
Wall Street analysts forecast BCRX stock price to rise
9 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
19.45
High
32.00
Current: 0.000
sliders
Low
8.00
Averages
19.45
High
32.00
Cantor Fitzgerald
NULL
to
Overweight
maintain
$27 -> $29
AI Analysis
2026-06-30
New
Reason
Cantor Fitzgerald
Price Target
$27 -> $29
AI Analysis
2026-06-30
New
maintain
NULL
to
Overweight
Reason
Cantor Fitzgerald raised the firm's price target on BioCryst to $29 from $27 and keeps an Overweight rating on the shares. The long-term commercial outlook for a Q6M hereditary angioedema prophylaxis therapy is strong and unchanged, with expectations that a best-in-class agent could benefit from improved 12-month efficacy data versus 6-month results, supported by prior clinical precedents and model-based projections for navenibart, the analyst tells investors in a research note.
Citizens
Jonathan Wolleben
Outperform
maintain
$25 -> $28
2026-05-07
Reason
Citizens
Jonathan Wolleben
Price Target
$25 -> $28
2026-05-07
maintain
Outperform
Reason
Citizens analyst Jonathan Wolleben raised the firm's price target on BioCryst to $28 from $25 and keeps an Outperform rating on the shares. Orladeyo posted a typical seasonal Q1 dip with sales slightly below expectations but steady patient starts and reaffirmed 2026 guidance, while confidence remains high in longer-term growth driven by continued patient additions, pricing, international expansion through the Neopharmed deal, and pipeline opportunities including navenibart and BCX17725 that could support meaningful upside through the next decade, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for BCRX
Unlock Now

Valuation Metrics

The current forward P/E ratio for BioCryst Pharmaceuticals Inc (BCRX.O) is 86.96, compared to its 5-year average forward P/E of -21.66. For a more detailed relative valuation and DCF analysis to assess BioCryst Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-21.66
Current PE
86.96
Overvalued PE
87.56
Undervalued PE
-130.88

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-13.32
Current EV/EBITDA
-257.74
Overvalued EV/EBITDA
61.01
Undervalued EV/EBITDA
-87.66

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.08
Current PS
3.33
Overvalued PS
8.31
Undervalued PS
1.85

Financials

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N
Nantahala Capital Management, LLC
Holding
BCRX
+27.24%
3M Return
P
Perceptive Advisors LLC
Holding
BCRX
+20.74%
3M Return
R
RA Capital Management, L.P.
Holding
BCRX
+19.70%
3M Return
D
Deerfield Management Company, L.P.
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BCRX
+19.56%
3M Return
B
Baker Bros. Advisors LP
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+17.23%
3M Return
K
Kynam Capital Management, LP
Holding
BCRX
+16.15%
3M Return

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Frequently Asked Questions

What is BioCryst Pharmaceuticals Inc (BCRX) stock price today?

The current price of BCRX is 9.92 USD — it has increased 3.87

What is BioCryst Pharmaceuticals Inc (BCRX)'s business?

BioCryst Pharmaceuticals, Inc. is a biotechnology company focused on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. Its marketed products include oral, once-daily ORLADEYO for the prevention of HAE attacks and RAPIVAB (peramivir injection) for the treatment of acute uncomplicated influenza in the United States. Its other products and product candidates include BCX17725, navenibart, Avoralstat, STAR-0310, RAPIACTA (peramivir injection) and PERAMIFLU (peramivir injection). The RAPIVAB (peramivir injection) is approved in the United States for the treatment of acute uncomplicated influenza for patients six months and older. Peramivir injection is also approved in Canada (RAPIVAB), Australia (RAPIVAB), Japan (RAPIACTA), Taiwan (RAPIACTA), and Korea (PERAMIFLU). It has also obtained an early-stage program for atopic dermatitis (AD), STAR0310.

What is the price predicton of BCRX Stock?

Wall Street analysts forecast BCRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BCRX is19.45 USD with a low forecast of 8.00 USD and a high forecast of 32.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is BioCryst Pharmaceuticals Inc (BCRX)'s revenue for the last quarter?

BioCryst Pharmaceuticals Inc revenue for the last quarter amounts to 156.41M USD, increased 7.48

What is BioCryst Pharmaceuticals Inc (BCRX)'s earnings per share (EPS) for the last quarter?

BioCryst Pharmaceuticals Inc. EPS for the last quarter amounts to -2.98 USD, decreased

How many employees does BioCryst Pharmaceuticals Inc (BCRX). have?

BioCryst Pharmaceuticals Inc (BCRX) has 435 emplpoyees as of June 30 2026.

What is BioCryst Pharmaceuticals Inc (BCRX) market cap?

Today BCRX has the market capitalization of 2.43B USD.