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BCRX Overview

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0.000(0.000%)Aft-market
ET
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ET
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Intellectia

Loading chart...

High
9.010
Open
8.970
VWAP
8.84
Vol
3.88M
Mkt Cap
2.28B
Low
8.730
Amount
34.25M
EV/EBITDA(TTM)
9.06
Total Shares
254.16M
EV
2.89B
EV/OCF(TTM)
9.22
P/S(TTM)
2.28
BioCryst Pharmaceuticals, Inc. is a biotechnology company focused on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. Its marketed products include oral, once-daily ORLADEYO for the prevention of hereditary angioedema (HAE) attacks and RAPIVAB (peramivir injection) for the treatment of acute uncomplicated influenza in the United States. Its other products and product candidates include BCX10013, RAPIACTA (peramivir injection), PERAMIFLU (peramivir injection), and early-stage discovery programs. BCX10013, is a potent and specific Factor D inhibitor. RAPIACTA focuses on uncomplicated seasonal influenza. The RAPIVAB (peramivir injection) is approved in the United States for the treatment of acute uncomplicated influenza for patients six months and older. Its portfolio also includes navenibart, which is a late-stage, long-acting plasma kallikrein inhibitor. It has also obtained an early-stage program for atopic dermatitis, STAR0310.
Show More

Events Timeline

(ET)
2026-05-06
08:00:00
BioCryst Reports Q1 Revenue of $156.41M
select
2026-05-06
08:00:00
Company Maintains FY26 ORLADEYO Revenue Outlook of $625M-$645M
select
2026-05-04 (ET)
2026-05-04
07:20:00
BioCryst Enters License Agreement with Neopharmed Gentili, Receives $70M Upfront
select
2026-04-06 (ET)
2026-04-06
07:10:00
BioCryst Appoints Sandeep Menon as Chief R&D Officer
select
2026-03-04 (ET)
2026-03-04
07:10:00
BioCryst Grants 65,850 Restricted Stock Units to New Employees
select
2026-02-26 (ET)
2026-02-26
07:20:00
BioCryst Reports Q4 Revenue of $406.555M, Achieves Full-Year Profitability
select
2026-02-26
07:20:00
Sees FY26 Orladeyo Revenue at $625M-$645M
select

News

seekingalpha
9.5
05-06seekingalpha
BioCryst Pharmaceuticals Q1 2026 Earnings Call Highlights
  • Strong Financial Performance: BioCryst reported ORLADEYO net revenue of $148.3 million for Q1 2026, aligning with expectations and reflecting a 21% year-over-year increase, indicating robust market demand and sustained revenue growth potential.
  • R&D Progress on Track: The pivotal ALPHA-ORBIT trial for navenibart has exceeded expectations, with approximately 145 patients expected to be enrolled by the end of next month, laying the groundwork for future regulatory submissions and enhancing the company's competitive position in the rare disease space.
  • Market Competition Management: Despite facing new competition, demand for new prescriptions among patients aged 12 and older remains stable, demonstrating continued trust in ORLADEYO from both physicians and patients, which is expected to drive further market share growth.
  • Supply Chain Challenges: Although a manufacturing issue for pediatric formulations has been identified that will delay initial product fulfillment, management has stated that this delay will not impact the revenue guidance for 2026, reflecting the company's confidence in future performance.
seekingalpha
9.5
05-06seekingalpha
BioCryst Pharmaceuticals Q1 Earnings Analysis
  • Disappointing Earnings: BioCryst Pharmaceuticals reported a Q1 GAAP EPS of -$2.98, missing expectations by $3.03, indicating challenges in profitability that could negatively impact investor confidence.
  • Revenue Growth: The company achieved Q1 revenue of $156.4 million, a 7.5% year-over-year increase, exceeding expectations by $5.28 million, suggesting sustained demand for its products and potentially laying a foundation for future financial performance.
  • 2026 Financial Outlook: BioCryst maintained its expectation for global net ORLADEYO revenue in 2026 to be between $625 million and $645 million, reflecting confidence in its core product while indicating stability in future revenue projections.
  • Operating Expense Projections: The company expects non-GAAP operating expenses for 2026 to remain between $450 million and $470 million, indicating ongoing efforts to control costs, which may aid in achieving profitability in the future.
seekingalpha
9.5
05-05seekingalpha
BioCryst Pharmaceuticals to Announce Q1 Earnings on May 6
  • Earnings Announcement: BioCryst Pharmaceuticals (BCRX) is set to announce its Q1 2023 earnings on May 6 before the market opens, with consensus EPS estimated at $0.11 and revenue expected to reach $151.12 million, reflecting a 3.9% year-over-year growth.
  • Historical Performance: Over the past two years, BCRX has beaten EPS estimates 50% of the time and revenue estimates 88% of the time, indicating a level of stability and confidence in the company's financial performance.
  • Estimate Revision Trends: In the last three months, there have been no upward revisions to EPS estimates and one downward revision, while revenue estimates saw one upward revision but four downward revisions, suggesting a cautious outlook from the market regarding the company's future performance.
  • Future Revenue Target: BioCryst has set a revenue target of $625 million to $645 million for ORLADEYO in 2026, as the HAE pipeline advances, demonstrating the company's positive outlook for future growth opportunities.
Newsfilter
5.0
04-06Newsfilter
BioCryst Appoints New Chief R&D Officer to Drive Rare Disease Strategy
  • New R&D Leadership: BioCryst Pharmaceuticals has appointed Dr. Sandeep M. Menon as Chief Research and Development Officer, bringing a wealth of experience from Alnylam Pharmaceuticals that is expected to invigorate the company's focus on rare disease therapies.
  • New Strategic Phase: Following the acquisition of Astria Therapeutics and the navenibart program, BioCryst is entering a new phase of execution aimed at enhancing company value through the development and commercialization of rare disease therapies.
  • Clinical Development Achievements: Dr. Menon previously led the FDA approval of AMVUTTRA® at Alnylam, showcasing his exceptional capabilities in managing complex programs and scaling global R&D organizations, which will aid BioCryst in improving its R&D success rates.
  • Future Growth Potential: The addition of Dr. Menon is seen as a critical inflection point for BioCryst in the rare disease sector, with expectations that he will drive continued growth in the development of innovative therapies and market expansion.
stocktwits
4.5
03-24stocktwits
Rising Oil Prices and Middle East Tensions Impact Market Sentiment
  • Cautious Market Sentiment: Elevated oil prices and tensions in the Middle East have kept investors cautious about market direction, even as Dow and S&P 500 futures rose by 0.2% and Nasdaq and Russell 2000 futures increased by 0.3%, indicating signs of recovery.
  • Supply Chain Concerns Intensify: AI stocks remain in focus amid heightened geopolitical scrutiny over chip exports, particularly as U.S. Senators reportedly demand a suspension of Nvidia's GPU export licenses to China and Southeast Asia, which could impact its market performance.
  • Retail Sentiment Weakens: The SPDR S&P 500 ETF (SPY) and Invesco QQQ Trust (QQQ) reflect ‘extremely bearish’ and ‘bearish’ retail sentiment, respectively, indicating a lack of confidence among investors regarding future market trends, which may affect capital inflows.
  • Key Earnings Reports Ahead: Gamestop (GME) is set to report earnings after the market close today, with investors keenly watching for updates on its Bitcoin treasury and AI-driven pivot, which could significantly impact its stock price.
stocktwits
8.5
03-24stocktwits
BioCryst Shares Surge in After-Hours Trading Amid Speculation of Major Pharma Interest — Retail Sentiment Reaches Highest Level Since 2026
  • Retail Traders Debate Buyout Timing: Retail traders are discussing the timing and pricing of a potential buyout of BioCryst Pharmaceuticals, with some speculating on an all-cash offer and others considering various takeover scenarios.

  • Stock Performance and Investor Sentiment: BioCryst's stock jumped about 11% in after-hours trading, reflecting strong retail sentiment and speculation about a U.S. biopharma firm potentially acquiring the company, which has a market cap exceeding $15 billion.

  • Growth and Revenue Highlights: The company reported $601 million in revenue and $214 million in non-GAAP operating profit last year, with its growth anchored by its oral treatment, Orladeyo, which is unique in the market.

  • Future Outlook and Market Positioning: Analysts suggest that the stock could reach $16-$18 in a buyout scenario, while others warn of potential declines if competition increases, emphasizing the importance of market positioning and investor confidence in future acquisitions.

Wall Street analysts forecast BCRX stock price to rise
11 Analyst Rating
Wall Street analysts forecast BCRX stock price to rise
9 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
19.45
High
32.00
Current: 0.000
sliders
Low
8.00
Averages
19.45
High
32.00
Citizens
Jonathan Wolleben
Outperform
maintain
$25 -> $28
AI Analysis
2026-05-07
Reason
Citizens
Jonathan Wolleben
Price Target
$25 -> $28
AI Analysis
2026-05-07
maintain
Outperform
Reason
Citizens analyst Jonathan Wolleben raised the firm's price target on BioCryst to $28 from $25 and keeps an Outperform rating on the shares. Orladeyo posted a typical seasonal Q1 dip with sales slightly below expectations but steady patient starts and reaffirmed 2026 guidance, while confidence remains high in longer-term growth driven by continued patient additions, pricing, international expansion through the Neopharmed deal, and pipeline opportunities including navenibart and BCX17725 that could support meaningful upside through the next decade, the analyst tells investors in a research note.
RBC Capital
Outperform
maintain
$13 -> $14
2026-04-07
Reason
RBC Capital
Price Target
$13 -> $14
2026-04-07
maintain
Outperform
Reason
RBC Capital raised the firm's price target on BioCryst to $14 from $13 and keeps an Outperform rating on the shares as part of the firm's broader research note previewing Q1 results in Biotech. Seasonal headwinds around gross/net, reimbursement resets, and fewer selling days may be exacerbated in Q1 by weather impact, particularly for launching and in-clinic products, but the robust return of M&A, coupled with clarity on limited tariff/Most Favored Nation drug pricing impacts, could help offset both this and broader macro volatility while keeping sector perceptions favorable, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for BCRX
Unlock Now

Valuation Metrics

The current forward P/E ratio for BioCryst Pharmaceuticals Inc (BCRX.O) is 75.19, compared to its 5-year average forward P/E of -23.92. For a more detailed relative valuation and DCF analysis to assess BioCryst Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-23.92
Current PE
75.19
Overvalued PE
84.25
Undervalued PE
-132.09

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-7.86
Current EV/EBITDA
-243.08
Overvalued EV/EBITDA
57.10
Undervalued EV/EBITDA
-72.82

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.59
Current PS
3.08
Overvalued PS
9.97
Undervalued PS
1.20

Financials

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Holding
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+10.36%
3M Return
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3M Return
D
Deerfield Management Company, L.P.
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Baker Bros. Advisors LP
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Frequently Asked Questions

What is BioCryst Pharmaceuticals Inc (BCRX) stock price today?

The current price of BCRX is 8.77 USD — it has decreased -2.23

What is BioCryst Pharmaceuticals Inc (BCRX)'s business?

BioCryst Pharmaceuticals, Inc. is a biotechnology company focused on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. Its marketed products include oral, once-daily ORLADEYO for the prevention of hereditary angioedema (HAE) attacks and RAPIVAB (peramivir injection) for the treatment of acute uncomplicated influenza in the United States. Its other products and product candidates include BCX10013, RAPIACTA (peramivir injection), PERAMIFLU (peramivir injection), and early-stage discovery programs. BCX10013, is a potent and specific Factor D inhibitor. RAPIACTA focuses on uncomplicated seasonal influenza. The RAPIVAB (peramivir injection) is approved in the United States for the treatment of acute uncomplicated influenza for patients six months and older. Its portfolio also includes navenibart, which is a late-stage, long-acting plasma kallikrein inhibitor. It has also obtained an early-stage program for atopic dermatitis, STAR0310.

What is the price predicton of BCRX Stock?

Wall Street analysts forecast BCRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BCRX is19.45 USD with a low forecast of 8.00 USD and a high forecast of 32.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is BioCryst Pharmaceuticals Inc (BCRX)'s revenue for the last quarter?

BioCryst Pharmaceuticals Inc revenue for the last quarter amounts to 156.41M USD, increased 7.48

What is BioCryst Pharmaceuticals Inc (BCRX)'s earnings per share (EPS) for the last quarter?

BioCryst Pharmaceuticals Inc. EPS for the last quarter amounts to -2.98 USD, decreased

How many employees does BioCryst Pharmaceuticals Inc (BCRX). have?

BioCryst Pharmaceuticals Inc (BCRX) has 435 emplpoyees as of May 20 2026.

What is BioCryst Pharmaceuticals Inc (BCRX) market cap?

Today BCRX has the market capitalization of 2.28B USD.