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MLYS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
32.140
Open
31.630
VWAP
31.54
Vol
1.09M
Mkt Cap
2.60B
Low
30.970
Amount
34.42M
EV/EBITDA(TTM)
--
Total Shares
82.50M
EV
1.95B
EV/OCF(TTM)
--
P/S(TTM)
--
Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.
Show More

Events Timeline

(ET)
2026-05-31
17:10:00
Mineralys Therapeutics Presents Clinical Data for Lorundrostat
select
2026-05-18 (ET)
2026-05-18
09:20:00
Jefferies Analyst Says AstraZeneca's Baxfendy FDA Approval is Positive for Mineralys
select
2026-05-06 (ET)
2026-05-06
17:00:00
Mineralys Therapeutics Advances lorundrostat Application
select
2026-03-31 (ET)
2026-03-31
07:10:00
Immunic Appoints Jon Congleton to Board of Directors
select
2026-03-24 (ET)
2026-03-24
08:10:00
Mineralys Therapeutics Appoints Jeffrey Munsie as Chief Legal Officer
select
2026-03-12 (ET)
2026-03-12
16:40:00
Mineralys Submits First NDA Application for Hypertension
select

News

NASDAQ.COM
6.5
05-31NASDAQ.COM
Velan Capital Reduces Stake in Mineralys Therapeutics
  • Stake Reduction: According to an SEC filing dated May 15, 2026, Velan Capital sold 140,000 shares of Mineralys Therapeutics in Q1, with an estimated transaction value of $4.11 million, indicating a cautious outlook on the company's future prospects.
  • Decline in Position Value: Following the sale, Velan Capital's position value decreased by $5.18 million, reflecting the dual impact of trading activities and stock price changes, suggesting a weakening market confidence in Mineralys.
  • Current Holdings: As of quarter-end, Velan Capital holds 11,000 shares of Mineralys valued at $297,990, with this stake now representing only 0.19% of its total assets under management, thus falling outside its top five holdings.
  • Financial Status Analysis: Mineralys reported a loss of $39.3 million in Q1, but with $646 million in cash on hand, it should be able to sustain operations while the FDA reviews its lorundrostat application, although the lack of approved products poses ongoing risks.
Fool
6.5
05-31Fool
Velan Capital Reduces Stake in Mineralys Therapeutics
  • Share Reduction Details: According to an SEC filing dated May 15, 2026, Velan Capital sold 140,000 shares of Mineralys Therapeutics in Q1, valued at approximately $4.11 million, leaving it with 11,000 shares worth about $297,990, resulting in a net position decline of $5.18 million due to both share sales and price fluctuations.
  • Holding Proportion Change: Following this reduction, Mineralys Therapeutics now represents only 0.19% of Velan Capital's reportable U.S. equity AUM, indicating a waning confidence in the company, while its top holdings include PRAX, TARA, and STRO.
  • Market Performance Analysis: As of May 14, 2026, Mineralys Therapeutics shares were priced at $27.27, reflecting an 80.5% increase over the past year, significantly outperforming the S&P 500 by 53.18 percentage points, showcasing its strong position in the biopharmaceutical market.
  • FDA Review Progress: Mineralys's lead product candidate, lorundrostat, is currently under FDA review, with an expected approval decision by December 22, 2026, which could present significant market opportunities for the company, despite reporting a loss of $39.3 million in Q1 and having no approved products yet.
Newsfilter
9.0
05-30Newsfilter
Lorundrostat Shows Significant Efficacy in Chronic Kidney Disease Patients
  • Clinical Trial Results: In a study involving 800 participants, lorundrostat achieved a significant reduction of 9.6 mmHg in systolic blood pressure among chronic kidney disease patients, highlighting its potential in managing hypertension and CKD effectively.
  • Urinary Albumin Reduction: Among 84 participants with baseline albuminuria, lorundrostat treatment led to a remarkable 52.2% reduction in urinary albumin-to-creatinine ratio after 12 weeks, indicating its potential for renal protection and improving long-term patient outcomes.
  • Safety Profile: Over the 12-week study, lorundrostat demonstrated a low incidence of confirmed hyperkalemia at 2.4% in CKD patients, showcasing its favorable safety profile and enhancing its attractiveness as a treatment option.
  • FDA Review Progress: Lorundrostat is currently under review by the U.S. FDA, with results expected by December 22, 2026, which could open new market opportunities for the company to address the unmet needs of hypertension patients.
seekingalpha
9.5
05-07seekingalpha
Mineralys Therapeutics Q1 2026 Earnings Call Highlights
  • FDA Acceptance Milestone: Mineralys Therapeutics successfully received FDA acceptance for the NDA of lorundrostat in Q1 2026, with a PDUFA target date set for December 22, 2026, establishing a crucial foundation for future commercialization efforts.
  • Stable Financial Position: As of March 31, 2026, the company reported cash and cash equivalents totaling $646.1 million, indicating that these resources are expected to support operations into 2028, reflecting strong financial health.
  • Decline in R&D Expenses: R&D expenses for Q1 2026 were $24.4 million, significantly down from $37.9 million in Q1 2025, showcasing a strategic shift in spending during the clinical trial phase.
  • Market Access Strategy: Management emphasized a focus on market access for fourth-line hypertension patients, ensuring “parity access” with competitors to enhance the market competitiveness of lorundrostat.
Newsfilter
5.0
05-05Newsfilter
Mineralys Grants Stock Options and RSUs to New Employees
  • Stock Option Grants: On May 4, 2026, Mineralys Therapeutics granted a total of 29,760 stock options to two new non-executive employees, aimed at attracting and retaining talent, thereby enhancing the company's competitive edge in the biopharmaceutical sector.
  • Restricted Stock Units: The company also awarded 22,320 restricted stock units that will vest over four years, with the first vesting occurring on the anniversary of the grant date, reflecting the company's long-term commitment to new employees and promoting team stability.
  • Vesting Mechanism: The stock options will vest gradually over four years, with 25% vesting in the first year and 1/48 vesting monthly thereafter, ensuring that employees contribute continuously during their tenure, which enhances their sense of belonging.
  • Compliance Assurance: This grant complies with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's adherence to regulations and transparency in attracting new employees, which further boosts investor confidence in the company.
Fool
5.0
04-07Fool
Mineralys CEO Sells 75,000 Shares Amid Market Fluctuations
  • Executive Stock Sale: Jon Congleton, CEO of Mineralys Therapeutics, sold 75,000 shares on March 31 through multiple open-market transactions valued at approximately $1.97 million, indicating active trading behavior in the company's stock.
  • Holding Proportion Change: The sale impacted 9.61% of Congleton's direct holdings, leaving him with 705,051 shares, which represents about 58.6% of his position from August 2023, suggesting he still retains confidence in the company.
  • Trading Plan Context: The stock sale was executed under Congleton's Rule 10b5-1 trading plan adopted in December 2025, which is designed to avoid legal issues related to insider trading, reflecting his cautious approach to compliance.
  • Market Reaction and Risks: While Congleton's sale may raise market concerns, Mineralys stock has significantly dropped from its 52-week high of $47.65 last November in 2026, prompting investors to carefully assess the impact of the company's clinical trial results on future stock performance.
Wall Street analysts forecast MLYS stock price to rise
6 Analyst Rating
Wall Street analysts forecast MLYS stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
Goldman Sachs
Buy
to
Buy
downgrade
$49 -> $42
AI Analysis
2026-05-07
Reason
Goldman Sachs
Price Target
$49 -> $42
AI Analysis
2026-05-07
downgrade
Buy
to
Buy
Reason
Goldman Sachs lowered the firm's price target on Mineralys Therapeutics to $42 from $49 and keeps a Buy rating on the shares.
TD Cowen
Buy
initiated
2026-04-27
Reason
TD Cowen
Price Target
2026-04-27
initiated
Buy
Reason
TD Cowen initiated coverage of Mineralys Therapeutics with a Buy rating and no price target. The company's lorundrostat has broad, blockbuster potential in uncontrolled and resistant hypertension a $5B market, the analyst tells investors in a research note. TD believes lorundrostat will have a better label and favorable pricing relative to baxdrostat.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MLYS
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Valuation Metrics

The current forward P/E ratio for Mineralys Therapeutics Inc (MLYS.O) is 0.00, compared to its 5-year average forward P/E of -5.81. For a more detailed relative valuation and DCF analysis to assess Mineralys Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.81
Current PE
0.00
Overvalued PE
-1.04
Undervalued PE
-10.57

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.85
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.24
Undervalued EV/EBITDA
-7.95

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2.48
Current PS
21.39
Overvalued PS
9.08
Undervalued PS
-4.11

Financials

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Annual
Quarterly

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Whales Holding MLYS

N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
MLYS
+25.16%
3M Return
A
Artal Group S.A.
Holding
MLYS
+11.24%
3M Return
A
Affinity Asset Advisors, LLC
Holding
MLYS
+7.94%
3M Return
R
Rock Springs Capital Management LP
Holding
MLYS
+7.73%
3M Return
S
Samlyn Capital, LLC
Holding
MLYS
+5.72%
3M Return
O
OrbiMed Advisors LLC
Holding
MLYS
-0.35%
3M Return

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Frequently Asked Questions

What is Mineralys Therapeutics Inc (MLYS) stock price today?

The current price of MLYS is 31.5 USD — it has decreased -0.13

What is Mineralys Therapeutics Inc (MLYS)'s business?

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.

What is the price predicton of MLYS Stock?

Wall Street analysts forecast MLYS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MLYS is52.60 USD with a low forecast of 46.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mineralys Therapeutics Inc (MLYS)'s revenue for the last quarter?

Mineralys Therapeutics Inc revenue for the last quarter amounts to -45.34M USD, increased 2.01

What is Mineralys Therapeutics Inc (MLYS)'s earnings per share (EPS) for the last quarter?

Mineralys Therapeutics Inc. EPS for the last quarter amounts to -39471000.00 USD, decreased -13.23

How many employees does Mineralys Therapeutics Inc (MLYS). have?

Mineralys Therapeutics Inc (MLYS) has 76 emplpoyees as of June 01 2026.

What is Mineralys Therapeutics Inc (MLYS) market cap?

Today MLYS has the market capitalization of 2.60B USD.