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MLYS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
30.150
Open
29.710
VWAP
29.65
Vol
718.91K
Mkt Cap
2.45B
Low
29.060
Amount
21.31M
EV/EBITDA(TTM)
--
Total Shares
82.50M
EV
1.79B
EV/OCF(TTM)
--
P/S(TTM)
--
Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.
Show More

Events Timeline

(ET)
2026-05-06
17:00:00
Mineralys Therapeutics Advances lorundrostat Application
select
2026-03-31 (ET)
2026-03-31
07:10:00
Immunic Appoints Jon Congleton to Board of Directors
select
2026-03-24 (ET)
2026-03-24
08:10:00
Mineralys Therapeutics Appoints Jeffrey Munsie as Chief Legal Officer
select
2026-03-12 (ET)
2026-03-12
16:40:00
Mineralys Submits First NDA Application for Hypertension
select
2026-03-09 (ET)
2026-03-09
16:40:00
Mineralys Therapeutics' Lorundrostat NDA Accepted by FDA
select

News

seekingalpha
9.5
05-07seekingalpha
Mineralys Therapeutics Q1 2026 Earnings Call Highlights
  • FDA Acceptance Milestone: Mineralys Therapeutics successfully received FDA acceptance for the NDA of lorundrostat in Q1 2026, with a PDUFA target date set for December 22, 2026, establishing a crucial foundation for future commercialization efforts.
  • Stable Financial Position: As of March 31, 2026, the company reported cash and cash equivalents totaling $646.1 million, indicating that these resources are expected to support operations into 2028, reflecting strong financial health.
  • Decline in R&D Expenses: R&D expenses for Q1 2026 were $24.4 million, significantly down from $37.9 million in Q1 2025, showcasing a strategic shift in spending during the clinical trial phase.
  • Market Access Strategy: Management emphasized a focus on market access for fourth-line hypertension patients, ensuring “parity access” with competitors to enhance the market competitiveness of lorundrostat.
Newsfilter
5.0
05-05Newsfilter
Mineralys Grants Stock Options and RSUs to New Employees
  • Stock Option Grants: On May 4, 2026, Mineralys Therapeutics granted a total of 29,760 stock options to two new non-executive employees, aimed at attracting and retaining talent, thereby enhancing the company's competitive edge in the biopharmaceutical sector.
  • Restricted Stock Units: The company also awarded 22,320 restricted stock units that will vest over four years, with the first vesting occurring on the anniversary of the grant date, reflecting the company's long-term commitment to new employees and promoting team stability.
  • Vesting Mechanism: The stock options will vest gradually over four years, with 25% vesting in the first year and 1/48 vesting monthly thereafter, ensuring that employees contribute continuously during their tenure, which enhances their sense of belonging.
  • Compliance Assurance: This grant complies with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's adherence to regulations and transparency in attracting new employees, which further boosts investor confidence in the company.
Fool
5.0
04-07Fool
Mineralys CEO Sells 75,000 Shares Amid Market Fluctuations
  • Executive Stock Sale: Jon Congleton, CEO of Mineralys Therapeutics, sold 75,000 shares on March 31 through multiple open-market transactions valued at approximately $1.97 million, indicating active trading behavior in the company's stock.
  • Holding Proportion Change: The sale impacted 9.61% of Congleton's direct holdings, leaving him with 705,051 shares, which represents about 58.6% of his position from August 2023, suggesting he still retains confidence in the company.
  • Trading Plan Context: The stock sale was executed under Congleton's Rule 10b5-1 trading plan adopted in December 2025, which is designed to avoid legal issues related to insider trading, reflecting his cautious approach to compliance.
  • Market Reaction and Risks: While Congleton's sale may raise market concerns, Mineralys stock has significantly dropped from its 52-week high of $47.65 last November in 2026, prompting investors to carefully assess the impact of the company's clinical trial results on future stock performance.
NASDAQ.COM
8.0
03-31NASDAQ.COM
Dell and Super Group See Surge in Options Trading Volume
  • Dell Options Volume: Dell Technologies saw options trading volume of 56,231 contracts, representing approximately 5.6 million shares, which is about 59.2% of its average daily trading volume over the past month, indicating heightened market interest in its future performance.
  • High-Frequency Contracts: Notably, the $210 strike put option expiring March 19, 2027, has seen 5,000 contracts traded today, equating to approximately 500,000 shares, suggesting an increasing bearish sentiment among investors regarding Dell's stock price.
  • Super Group Options Activity: Super Group Ltd recorded options trading volume of 12,084 contracts, representing around 1.2 million shares, which constitutes about 58.1% of its average daily trading volume over the past month, reflecting sustained market interest in the company.
  • Bullish Call Options: Within Super Group, the $8.75 strike call option expiring April 17, 2026, has traded 6,499 contracts today, representing approximately 649,900 shares, indicating a bullish outlook among investors for the company's future stock performance.
NASDAQ.COM
6.5
03-20NASDAQ.COM
ETF Analysis: FTLS Implied Upside of 21.41%
  • FTLS Potential Upside: The First Trust Long/Short Equity ETF (FTLS) has an implied analyst target price of $84.44 per unit, while trading at $69.55, indicating a potential upside of 21.41%, reflecting investor optimism about the ETF's future performance.
  • MLYS Stock Analysis: Mineralys Therapeutics Inc (MLYS) trades at $23.28, with an analyst target price of $50.00, suggesting a potential upside of 114.78%, which indicates strong market confidence in its future growth prospects.
  • Q Company Outlook: Qnity Electronics, Inc. (Q) has a current share price of $111.94, with an analyst target price of $233.67, showing an upside of 108.74%, highlighting analysts' very optimistic expectations for its future performance.
  • LIF Investment Potential: Life360 Inc (LIF) is currently priced at $39.27, with an analyst target price of $75.97, representing a potential upside of 93.45%, further emphasizing the market's positive outlook on the company.
seekingalpha
9.5
03-13seekingalpha
Mineralys Therapeutics Q4 2025 Earnings Call Highlights
  • FDA NDA Acceptance: CEO Jon Congleton highlighted the FDA's acceptance of the NDA for lorundrostat, with a PDUFA target action date of December 22, 2026, marking a significant milestone that positions the company for rapid entry into the U.S. hypertension market.
  • Improved Financial Position: As of December 31, 2025, the company reported cash and cash equivalents totaling $656.6 million, a substantial increase from $198.2 million in 2024, indicating sufficient funding for planned clinical trials and regulatory activities.
  • Decrease in R&D Expenses: R&D expenses for 2025 were $132 million, down from $168.6 million in 2024, primarily due to the completion of the lorundrostat pivotal program, allowing the company to focus resources on market launch and commercialization strategies.
  • Market Opportunity Outlook: Management reiterated the market potential for lorundrostat in patients with resistant hypertension, expecting rapid uptake post-approval while also evaluating further indications and potential partnerships for international expansion.
Wall Street analysts forecast MLYS stock price to rise
6 Analyst Rating
Wall Street analysts forecast MLYS stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
Goldman Sachs
Buy
to
Buy
downgrade
$49 -> $42
AI Analysis
2026-05-07
New
Reason
Goldman Sachs
Price Target
$49 -> $42
AI Analysis
2026-05-07
New
downgrade
Buy
to
Buy
Reason
Goldman Sachs lowered the firm's price target on Mineralys Therapeutics to $42 from $49 and keeps a Buy rating on the shares.
TD Cowen
Buy
initiated
2026-04-27
Reason
TD Cowen
Price Target
2026-04-27
initiated
Buy
Reason
TD Cowen initiated coverage of Mineralys Therapeutics with a Buy rating and no price target. The company's lorundrostat has broad, blockbuster potential in uncontrolled and resistant hypertension a $5B market, the analyst tells investors in a research note. TD believes lorundrostat will have a better label and favorable pricing relative to baxdrostat.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MLYS
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Valuation Metrics

The current forward P/E ratio for Mineralys Therapeutics Inc (MLYS.O) is 0.00, compared to its 5-year average forward P/E of -5.81. For a more detailed relative valuation and DCF analysis to assess Mineralys Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.81
Current PE
0.00
Overvalued PE
-1.04
Undervalued PE
-10.57

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.85
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.24
Undervalued EV/EBITDA
-7.95

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2.16
Current PS
29.89
Overvalued PS
8.38
Undervalued PS
-4.06

Financials

AI Analysis
Annual
Quarterly

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Whales Holding MLYS

N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
MLYS
+17.01%
3M Return
A
Artal Group S.A.
Holding
MLYS
+16.80%
3M Return
B
Boothbay Fund Management, LLC
Holding
MLYS
+14.10%
3M Return
S
Suvretta Capital Management, LLC
Holding
MLYS
+12.77%
3M Return
R
Rock Springs Capital Management LP
Holding
MLYS
+1.75%
3M Return
S
Samlyn Capital, LLC
Holding
MLYS
-3.33%
3M Return

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Frequently Asked Questions

What is Mineralys Therapeutics Inc (MLYS) stock price today?

The current price of MLYS is 29.73 USD — it has increased 0.64

What is Mineralys Therapeutics Inc (MLYS)'s business?

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.

What is the price predicton of MLYS Stock?

Wall Street analysts forecast MLYS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MLYS is52.60 USD with a low forecast of 46.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mineralys Therapeutics Inc (MLYS)'s revenue for the last quarter?

Mineralys Therapeutics Inc revenue for the last quarter amounts to -45.34M USD, increased 2.01

What is Mineralys Therapeutics Inc (MLYS)'s earnings per share (EPS) for the last quarter?

Mineralys Therapeutics Inc. EPS for the last quarter amounts to -39471000.00 USD, decreased -13.23

How many employees does Mineralys Therapeutics Inc (MLYS). have?

Mineralys Therapeutics Inc (MLYS) has 76 emplpoyees as of May 12 2026.

What is Mineralys Therapeutics Inc (MLYS) market cap?

Today MLYS has the market capitalization of 2.45B USD.