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MLYS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
27.560
Open
24.070
VWAP
26.24
Vol
2.51M
Mkt Cap
2.23B
Low
24.070
Amount
65.84M
EV/EBITDA(TTM)
--
Total Shares
82.40M
EV
1.28B
EV/OCF(TTM)
--
P/S(TTM)
--
Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.
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Events Timeline

(ET)
2026-03-31
07:10:00
Immunic Appoints Jon Congleton to Board of Directors
select
2026-03-24 (ET)
2026-03-24
08:10:00
Mineralys Therapeutics Appoints Jeffrey Munsie as Chief Legal Officer
select
2026-03-12 (ET)
2026-03-12
16:40:00
Mineralys Submits First NDA Application for Hypertension
select
2026-03-09 (ET)
2026-03-09
16:40:00
Mineralys Therapeutics' Lorundrostat NDA Accepted by FDA
select

News

NASDAQ.COM
8.0
03-31NASDAQ.COM
Dell and Super Group See Surge in Options Trading Volume
  • Dell Options Volume: Dell Technologies saw options trading volume of 56,231 contracts, representing approximately 5.6 million shares, which is about 59.2% of its average daily trading volume over the past month, indicating heightened market interest in its future performance.
  • High-Frequency Contracts: Notably, the $210 strike put option expiring March 19, 2027, has seen 5,000 contracts traded today, equating to approximately 500,000 shares, suggesting an increasing bearish sentiment among investors regarding Dell's stock price.
  • Super Group Options Activity: Super Group Ltd recorded options trading volume of 12,084 contracts, representing around 1.2 million shares, which constitutes about 58.1% of its average daily trading volume over the past month, reflecting sustained market interest in the company.
  • Bullish Call Options: Within Super Group, the $8.75 strike call option expiring April 17, 2026, has traded 6,499 contracts today, representing approximately 649,900 shares, indicating a bullish outlook among investors for the company's future stock performance.
NASDAQ.COM
6.5
03-20NASDAQ.COM
ETF Analysis: FTLS Implied Upside of 21.41%
  • FTLS Potential Upside: The First Trust Long/Short Equity ETF (FTLS) has an implied analyst target price of $84.44 per unit, while trading at $69.55, indicating a potential upside of 21.41%, reflecting investor optimism about the ETF's future performance.
  • MLYS Stock Analysis: Mineralys Therapeutics Inc (MLYS) trades at $23.28, with an analyst target price of $50.00, suggesting a potential upside of 114.78%, which indicates strong market confidence in its future growth prospects.
  • Q Company Outlook: Qnity Electronics, Inc. (Q) has a current share price of $111.94, with an analyst target price of $233.67, showing an upside of 108.74%, highlighting analysts' very optimistic expectations for its future performance.
  • LIF Investment Potential: Life360 Inc (LIF) is currently priced at $39.27, with an analyst target price of $75.97, representing a potential upside of 93.45%, further emphasizing the market's positive outlook on the company.
seekingalpha
9.5
03-13seekingalpha
Mineralys Therapeutics Q4 2025 Earnings Call Highlights
  • FDA NDA Acceptance: CEO Jon Congleton highlighted the FDA's acceptance of the NDA for lorundrostat, with a PDUFA target action date of December 22, 2026, marking a significant milestone that positions the company for rapid entry into the U.S. hypertension market.
  • Improved Financial Position: As of December 31, 2025, the company reported cash and cash equivalents totaling $656.6 million, a substantial increase from $198.2 million in 2024, indicating sufficient funding for planned clinical trials and regulatory activities.
  • Decrease in R&D Expenses: R&D expenses for 2025 were $132 million, down from $168.6 million in 2024, primarily due to the completion of the lorundrostat pivotal program, allowing the company to focus resources on market launch and commercialization strategies.
  • Market Opportunity Outlook: Management reiterated the market potential for lorundrostat in patients with resistant hypertension, expecting rapid uptake post-approval while also evaluating further indications and potential partnerships for international expansion.
seekingalpha
9.5
03-12seekingalpha
Mineralys Therapeutics Q4 Earnings Beat Expectations
  • Earnings Performance: Mineralys Therapeutics reported a Q4 GAAP EPS of -$0.40, beating market expectations by $0.13, indicating improved financial management that may bolster investor confidence.
  • Significant Cash Reserves Growth: As of December 31, 2025, the company reported cash, cash equivalents, and investments totaling $656.6 million, a substantial increase from $198.2 million in 2024, reflecting a robust financial position that supports future R&D activities.
  • Sufficient Funding for Future Plans: Mineralys believes its current cash reserves will adequately fund planned clinical trials and regulatory activities through 2028, laying a solid foundation for long-term growth and enhancing market confidence in its future prospects.
  • Positive FDA Review Progress: The ongoing FDA review of its blood pressure drug has positively impacted Mineralys's market performance, signaling potential success in drug development and market entry strategies.
seekingalpha
9.0
03-10seekingalpha
FDA Accepts Marketing Application for Mineralys' Lorundrostat
  • FDA Application Accepted: Mineralys Therapeutics' marketing application for lorundrostat has been accepted by the FDA, marking a significant advancement in the treatment of hypertension, which is expected to enhance market recognition and investor confidence.
  • Clinical Trial Results: In the Phase 2 Explore-OSA trial, although no clinically meaningful difference was observed in the primary endpoint, the significant reduction in blood pressure and favorable safety profile were deemed clinically meaningful, indicating the drug's potential in difficult-to-control hypertension patients.
  • Market Outlook: The FDA has set a target action date of December 22, 2026, and if approved, this could open new revenue streams for the company and potentially secure a position in the competitive hypertension drug market.
  • CEO Commentary: CEO Jon Congleton noted that despite the primary endpoint not being met, the drug's blood pressure-lowering effects and safety profile remain clinically significant, reflecting the company's ongoing commitment to developing new therapies.
NASDAQ.COM
9.0
03-10NASDAQ.COM
Mineralys Therapeutics' NDA for Lorundrostat Accepted by FDA
  • FDA Acceptance: Mineralys Therapeutics announced that the FDA has accepted its New Drug Application for Lorundrostat, with a decision expected on December 22, 2026, marking a significant step in the company's potential market entry for hypertension treatment.
  • Clinical Trial Success: The NDA submission is supported by three positive clinical trials demonstrating Lorundrostat's safety and ability to control blood pressure over 24 hours, indicating its potential as a new treatment option for uncontrolled hypertension.
  • Explore-OSA Trial Findings: Although the Explore-OSA trial did not show a significant reduction in the apnea-hypopnea index (AHI), Lorundrostat demonstrated clinically meaningful blood pressure reductions and a favorable safety profile, enhancing its prospects for use in difficult-to-treat hypertension patients.
  • Upcoming Financial Results: The company is set to report its financial results for Q4 and the full year 2025 on March 12, 2026, with investors keenly awaiting insights into the financial implications of its drug development progress.
Wall Street analysts forecast MLYS stock price to rise
6 Analyst Rating
Wall Street analysts forecast MLYS stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
Current: 0.000
sliders
Low
46.00
Averages
52.60
High
56.00
BofA
Buy
maintain
$46 -> $51
AI Analysis
2026-03-13
Reason
BofA
Price Target
$46 -> $51
AI Analysis
2026-03-13
maintain
Buy
Reason
BofA raised the firm's price target on Mineralys Therapeutics to $51 from $46 and keeps a Buy rating on the shares following some corporate updates on the clinical development progress of lead drug lorundrostat for the treatment of uncontrolled hypertension that came with Q4 earnings. The firm's view is that lorundrostat's peak sales opportunity remains "underappreciated," the analyst tells investors.
Stifel
Buy
maintain
$45 -> $52
2025-12-19
Reason
Stifel
Price Target
$45 -> $52
2025-12-19
maintain
Buy
Reason
Stifel raised the firm's price target on Mineralys Therapeutics to $52 from $45 and keeps a Buy rating on the shares as part of a 2026 outlook note for the analyst's Biopharma coverage.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MLYS
Unlock Now

Valuation Metrics

The current forward P/E ratio for Mineralys Therapeutics Inc (MLYS.O) is -16.21, compared to its 5-year average forward P/E of -5.82. For a more detailed relative valuation and DCF analysis to assess Mineralys Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.82
Current PE
-16.21
Overvalued PE
-1.04
Undervalued PE
-10.60

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.86
Current EV/EBITDA
-10.89
Overvalued EV/EBITDA
0.24
Undervalued EV/EBITDA
-7.97

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding MLYS

A
Artal Group S.A.
Holding
MLYS
+11.60%
3M Return
B
Boothbay Fund Management, LLC
Holding
MLYS
+5.47%
3M Return
N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
MLYS
+2.07%
3M Return
R
RA Capital Management, L.P.
Holding
MLYS
-0.01%
3M Return
O
OrbiMed Advisors LLC
Holding
MLYS
-0.50%
3M Return
S
Suvretta Capital Management, LLC
Holding
MLYS
-1.50%
3M Return

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Frequently Asked Questions

What is Mineralys Therapeutics Inc (MLYS) stock price today?

The current price of MLYS is 27.09 USD — it has increased 15.23

What is Mineralys Therapeutics Inc (MLYS)'s business?

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing medicines to target hypertension, chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor (ASI) that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension, CKD and OSA. Lorundrostat is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone. It has completed the Target-HTN trial, a Phase II proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). It is also investigating the benefits of lorundrostat in subjects with hypertension and CKD and in subjects with hypertension and OSA.

What is the price predicton of MLYS Stock?

Wall Street analysts forecast MLYS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MLYS is52.60 USD with a low forecast of 46.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mineralys Therapeutics Inc (MLYS)'s revenue for the last quarter?

Mineralys Therapeutics Inc revenue for the last quarter amounts to -38.28M USD, decreased -26.05

What is Mineralys Therapeutics Inc (MLYS)'s earnings per share (EPS) for the last quarter?

Mineralys Therapeutics Inc. EPS for the last quarter amounts to -37903000.00 USD, decreased -43.30

How many employees does Mineralys Therapeutics Inc (MLYS). have?

Mineralys Therapeutics Inc (MLYS) has 76 emplpoyees as of April 01 2026.

What is Mineralys Therapeutics Inc (MLYS) market cap?

Today MLYS has the market capitalization of 2.23B USD.