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ARCT Overview

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Intellectia

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High
7.940
Open
7.390
VWAP
7.71
Vol
209.44K
Mkt Cap
204.93M
Low
7.370
Amount
1.61M
EV/EBITDA(TTM)
--
Total Shares
28.42M
EV
-11.56M
EV/OCF(TTM)
--
P/S(TTM)
3.56
Arcturus Therapeutics Holdings Inc. is a commercial mRNA medicines and vaccines company focused on the development of infectious disease vaccines and opportunities within liver and respiratory rare diseases. The Company with enabling technologies, including LUNAR lipid-mediated delivery, STARR mRNA technology (sa-mRNA) and mRNA drug substances along with drug product manufacturing. It has developed KOSTAIVE, a self-amplifying messenger RNA (sa-mRNA) COVID vaccine. The Company’s pipeline includes RNA therapeutic candidates to potentially treat ornithine transcarbamylase (OTC) deficiency and cystic fibrosis (CF), along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. The Company's versatile RNA therapeutics platforms can be applied to multiple types of nucleic acid medicines, including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics.
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Events Timeline

(ET)
2026-05-07
16:30:00
Arcturus Q1 Revenue $2.1M, Below Consensus
select
2026-03-03 (ET)
2026-03-03
16:10:00
Arcturus Q4 Revenue $7.2M, Below Consensus
select
2025-12-30 (ET)
2025-12-30
16:10:00
Arcturus Therapeutics Files $500M Mixed Securities Shelf
select

News

seekingalpha
9.5
05-08seekingalpha
Arcturus Therapeutics Q1 2026 Earnings Call Insights
  • Clinical Trial Progress: Arcturus initiated its 12-week Phase II trial for ARCT-032 in Q1 2026, having surpassed one month of dosing, which signifies steady advancement in its rare disease pipeline and is expected to provide crucial support for future clinical data collection.
  • Strong Financial Position: As of March 31, 2026, the company reported $213.4 million in cash and cash equivalents, a decrease from $232.8 million on December 31, 2025, primarily due to reduced revenue from CSL collaborations, reflecting a strategic shift towards rare disease clinical programs.
  • R&D Expense Control: Quarterly R&D expenses decreased by $13.4 million year-over-year, driven by lower manufacturing costs associated with LUNAR-COVID and BARDA, although increased costs related to LUNAR-OTC partially offset these reductions, demonstrating effective cost management by the company.
  • Clear Regulatory Path: Following a meeting with the FDA, management received clear regulatory direction for ARCT-810, with an end-of-Phase II meeting planned for the second half of 2026, indicating a strategic focus on pediatric studies is becoming increasingly defined.
seekingalpha
9.5
05-07seekingalpha
Arcturus Therapeutics Q1 Earnings Analysis
  • Earnings Performance: Arcturus Therapeutics reported a Q1 GAAP EPS of -$0.95, beating expectations by $0.04, yet revenue plummeted to $2.06M, down 93% year-over-year, missing estimates by $4.81M, indicating significant operational challenges.
  • Cash Position: As of March 31, 2026, the company held $213.4 million in cash and equivalents, down from $232.8 million on December 31, 2025, reflecting pressure on cash management that could impact future R&D investments.
  • Market Reaction: The downgrade to a 'Hold' rating due to a shift in the CF program's population focus has diminished market confidence in Arcturus's growth potential, likely putting downward pressure on its stock price.
  • Future Outlook: The company plans to launch a 12-week Phase II CF trial in 2026 and anticipates regulatory clarity for ARCT-810, presenting potential new growth opportunities despite the current challenges.
seekingalpha
9.5
05-06seekingalpha
Arcturus Therapeutics Set to Announce Q1 Earnings on May 7
  • Earnings Announcement: Arcturus Therapeutics (ARCT) is set to release its Q1 earnings on May 7 after market close, with consensus EPS estimate at -$1.01 and revenue estimate at $6.87 million, reflecting a significant 76.6% year-over-year decline, indicating substantial challenges ahead for the company.
  • Historical Performance: Over the past year, ARCT has beaten EPS estimates 100% of the time and revenue estimates 75% of the time, suggesting a degree of financial stability despite current pressures, which may influence investor sentiment.
  • Estimate Adjustments: In the last three months, EPS estimates have seen one upward revision and three downward revisions, while revenue estimates have experienced one upward and one downward revision, highlighting market uncertainty regarding the company's future performance.
  • Clinical Trial Progress: Arcturus is advancing a 12-week Phase II clinical trial for cystic fibrosis (CF) and expects regulatory clarity for ARCT-810 in 2026, which could provide new growth momentum for the company moving forward.
Globenewswire
8.5
04-20Globenewswire
Transformation of Value in Biotechnology Sector
  • Value Shift: The biotechnology sector is undergoing a profound transformation where scientific progress is increasingly viewed as a measurable financial asset rather than just research expenditure, reinforced by fair-value accounting under U.S. GAAP that allows companies to reflect clinical advancements and commercialization timing on their balance sheets.
  • Investment Opportunities in Clinical Assets: Institutional investors are increasingly recognizing the investment value of clinical-stage biotech assets, even in the absence of current revenue, as Oncotelic Therapeutics exemplifies how scientific progress can directly influence financial positioning, significantly enhancing enterprise valuation through its diversified pipeline and 45% stake in GMP Bio.
  • Clinical Development Drives Valuation: As drug candidates advance through clinical development, their value significantly increases due to rising probabilities of success and proximity to commercialization, particularly for late-stage assets nearing regulatory approval, which tend to command a disproportionate share of enterprise value, reflecting investors' focus on pipeline asset maturity.
  • AI and Manufacturing Convergence: AI-driven drug development and GMP-compliant manufacturing platforms are accelerating timelines and improving scalability across the biotech industry, with Oncotelic Therapeutics demonstrating how to integrate oncology drug development with AI platforms, thereby linking scientific advancement with financial valuation and positioning the company favorably in the rapidly evolving biotech landscape.
Newsfilter
8.5
04-20Newsfilter
Biotechnology Sector Undergoes Value Transformation
  • Value Transformation Trend: The biotechnology sector is undergoing a profound transformation where scientific progress is increasingly viewed as a measurable financial asset, particularly as drug candidates approach commercialization, significantly enhancing companies' balance sheet values.
  • Fair Value Accounting Implementation: The adoption of fair-value accounting under U.S. GAAP allows life sciences companies to incorporate clinical progress, probability of success, and commercialization timing into financial reporting, thereby increasing transparency and attracting institutional investors to clinical-stage biotech assets.
  • Clinical Progress Drives Valuation: As drug candidates advance through clinical development, their value increases significantly due to rising probabilities of success and proximity to commercialization, with late-stage assets commanding a disproportionate share of enterprise value, reflecting investors' focus on pipeline asset maturity.
  • AI and GMP Manufacturing Convergence: The integration of AI-driven drug development and GMP-compliant manufacturing accelerates timelines and enhances scalability across the biotech industry, improving clinical development efficiency and market readiness, further driving the alignment of scientific progress with financial valuation.
Fool
6.5
03-25Fool
Cathie Wood Increases Holdings in Three Stocks Amid Market Volatility
  • Circle Internet Group Dynamics: Circle Internet Group's stock plummeted 20% on Tuesday due to concerns over cryptocurrency regulation discussions, yet it reported revenue growth of 53%, 66%, and 77% in its first three quarters; Cathie Wood's decision to buy more shares at this low point reflects her confidence in its long-term potential despite regulatory risks.
  • Arcturus Therapeutics Outlook: Arcturus Therapeutics reported a sharp revenue decline for three consecutive years, with projections indicating a further drop to one-fifth of its 2022 revenue by 2026; however, positive clinical trial developments and an extended cash runway to Q2 2028 may provide investor reassurance, prompting Wood to increase her stake, indicating optimism in the biotech sector.
  • 10x Genomics Steady Growth: 10x Genomics, a provider of life sciences tools, has seen significant revenue growth in seven of the past eight years, and despite profitability challenges, Wood's continued purchases over four consecutive trading days highlight her belief in its long-term success, particularly with the promising Chromium platform.
  • Market Environment Impact: Despite Ark Invest's largest fund declining 11% this year, nearly three times the market's drop, Cathie Wood's strategy of increasing her holdings in these stocks during market volatility suggests a bullish outlook for future rebounds, potentially attracting more investor interest in her investment approach.
Wall Street analysts forecast ARCT stock price to rise
4 Analyst Rating
Wall Street analysts forecast ARCT stock price to rise
2 Buy
2 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
7.00
Averages
14.00
High
20.00
Current: 0.000
sliders
Low
7.00
Averages
14.00
High
20.00
B. Riley
Buy
initiated
$22
AI Analysis
2026-03-18
Reason
B. Riley
Price Target
$22
AI Analysis
2026-03-18
initiated
Buy
Reason
B. Riley initiated coverage of Arcturus Therapeutics with a Buy rating and $22 price target. The firm says the company "stands out" given its lipid-enabled and unlocked nucleic acid modified RNA platform. The platform enables multi-tissue, safe, efficient, and effective delivery of messenger RNA that is applied to two wholly-owned rare disease programs, inhaled ARCT-032 for cystic fibrosis and intravenously administered ARCT-810 for ornithine transcarbamylase, the analyst tells investors in a research note.
Canaccord
Whitney Ijem
Buy
downgrade
$66 -> $21
2026-03-05
Reason
Canaccord
Whitney Ijem
Price Target
$66 -> $21
2026-03-05
downgrade
Buy
Reason
Canaccord analyst Whitney Ijem lowered the firm's price target on Arcturus Therapeutics to $21 from $66 and keeps a Buy rating on the shares. The firm updated its model following uneventful Q4 results as execution continues to be up and down and as a result the analyst adjusted thigs more conervatively than in the past. The adjustments adjustments still leave it with a valuation significantly above where shares currently trade, and as a result remain Buy rated.
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Valuation Metrics

The current forward P/E ratio for Arcturus Therapeutics Holdings Inc (ARCT.O) is 2.48, compared to its 5-year average forward P/E of -6.80. For a more detailed relative valuation and DCF analysis to assess Arcturus Therapeutics Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.80
Current PE
2.48
Overvalued PE
-0.02
Undervalued PE
-13.58

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.91
Current EV/EBITDA
-0.02
Overvalued EV/EBITDA
1.33
Undervalued EV/EBITDA
-5.15

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.00
Current PS
5.73
Overvalued PS
7.94
Undervalued PS
2.07

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Frequently Asked Questions

What is Arcturus Therapeutics Holdings Inc (ARCT) stock price today?

The current price of ARCT is 7.815 USD — it has increased 8.39

What is Arcturus Therapeutics Holdings Inc (ARCT)'s business?

Arcturus Therapeutics Holdings Inc. is a commercial mRNA medicines and vaccines company focused on the development of infectious disease vaccines and opportunities within liver and respiratory rare diseases. The Company with enabling technologies, including LUNAR lipid-mediated delivery, STARR mRNA technology (sa-mRNA) and mRNA drug substances along with drug product manufacturing. It has developed KOSTAIVE, a self-amplifying messenger RNA (sa-mRNA) COVID vaccine. The Company’s pipeline includes RNA therapeutic candidates to potentially treat ornithine transcarbamylase (OTC) deficiency and cystic fibrosis (CF), along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. The Company's versatile RNA therapeutics platforms can be applied to multiple types of nucleic acid medicines, including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics.

What is the price predicton of ARCT Stock?

Wall Street analysts forecast ARCT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ARCT is14.00 USD with a low forecast of 7.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Arcturus Therapeutics Holdings Inc (ARCT)'s revenue for the last quarter?

Arcturus Therapeutics Holdings Inc revenue for the last quarter amounts to 2.06M USD, decreased -92.99

What is Arcturus Therapeutics Holdings Inc (ARCT)'s earnings per share (EPS) for the last quarter?

Arcturus Therapeutics Holdings Inc. EPS for the last quarter amounts to -0.95 USD, increased 82.69

How many employees does Arcturus Therapeutics Holdings Inc (ARCT). have?

Arcturus Therapeutics Holdings Inc (ARCT) has 106 emplpoyees as of May 27 2026.

What is Arcturus Therapeutics Holdings Inc (ARCT) market cap?

Today ARCT has the market capitalization of 204.93M USD.