The chart below shows how BCRX performed 10 days before and after its earnings report, based on data from the past quarters. Typically, BCRX sees a +2.43% change in stock price 10 days leading up to the earnings, and a +0.19% change 10 days following the report. On the earnings day itself, the stock moves by -0.97%. This data can give you a slight idea of what to expect for the next quarter's release.
Positive
Revenue Growth Achievement: Orladeo revenue grew by 34% year-over-year, reflecting strong execution by the commercial team.
Non-GAAP Operating Profit Surge: The company generated a non-GAAP operating profit of over $60 million, three times larger than planned.
Increased Revenue Guidance: Orladeo revenue guidance for 2025 has been raised to $535 million to $550 million due to strong demand and improved affordability for Medicare patients.
Physician Interest in Orladeo: 97% of surveyed US HAE treaters are considering prescribing Orladeo, indicating strong physician interest and momentum.
Pediatric HAE Treatment Success: The APEX-P trial for pediatric Orladeo showed promising results, with children achieving early and sustained reduction in HAE attack rates.
BCX1775 Clinical Trial Progress: BCX1775 for Netherton syndrome is progressing in clinical trials, with initial data expected this year, aiming to provide a functional cure for patients.
Clinical Advancement in Diabetic Treatment: Avoralstat is set to move into the clinic for diabetic macular edema, addressing a significant unmet need in treatment options.
Future Revenue and Cash Flow: The company expects to achieve positive and sustainable quarterly cash flow and EPS in the second half of 2025, with a long-term goal of reaching $1 billion in global revenue by 2029.
Negative
Earnings Miss Report: BioCryst Pharmaceuticals, Inc. misses on earnings expectations, reporting an EPS of $-0.13 against expectations of $-0.07.
High Operating Expenses: Operating expenses for Q4 were approximately $115 million, which is significant given the revenue of $131.5 million, indicating a high cost structure relative to revenue.
Revenue Growth vs. Funding Uncertainty: Despite a strong revenue growth of 34% for Orladeo, the company still faces uncertainty around future government funding for RAPIVAB, which could impact overall revenue.
Revenue Guidance Update: The company has raised its revenue guidance for Orladeo, but the outcome of ongoing reauthorizations for Medicare patients remains uncertain, which could affect revenue projections.
Operating Expense Increase: The increase in operating expenses is expected due to higher costs associated with COGS, distribution fees, and incentive compensation, which could pressure margins going forward.
BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) Q4 2024 Earnings Call Transcript
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