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OLMA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
13.805
Open
13.750
VWAP
13.48
Vol
990.73K
Mkt Cap
1.17B
Low
13.210
Amount
13.35M
EV/EBITDA(TTM)
--
Total Shares
87.16M
EV
667.21M
EV/OCF(TTM)
--
P/S(TTM)
--
Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a proprietary, orally available complete estrogen receptor (ER) antagonist (CERAN) and a selective ER degrader (SERD), in a Phase 3 clinical trial called OPERA-01. It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. In addition, it is developing OP-3136, a potent KAT6 inhibitor, in a Phase 1 clinical trial. OP-3136 is a novel, orally available small molecule that potently and selectively inhibits KAT6.
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Events Timeline

(ET)
2026-03-16
07:10:00
Olema Oncology Raises $218.5 Million in Public Offering
select
2026-01-30 (ET)
2026-01-30
16:10:00
Olema Pharmaceuticals CFO Shane Kovacs to Depart on January 30
select

News

Fool
6.5
03-22Fool
Paradigm Increases Stake in Olema Pharmaceuticals
  • Share Acquisition: Paradigm Biocapital Advisors LP disclosed a purchase of 750,000 shares of Olema Pharmaceuticals in Q4 2025, representing an estimated $13.35 million trade that underscores confidence in the company.
  • Increased Ownership: This acquisition raised Paradigm's stake in Olema to approximately 4.5%, highlighting its significance within the reported assets under management.
  • Outstanding Stock Performance: As of February 17, 2026, Olema shares were priced at $14.08, reflecting a staggering 242% increase over the past year, significantly outperforming the S&P 500's 15% gain, indicating strong market recognition of its potential.
  • Strong Financial Position: Olema ended the year with over $500 million in cash and successfully raised $200 million, providing ample financial support for upcoming pivotal moments in its clinical pipeline.
NASDAQ.COM
6.5
03-22NASDAQ.COM
Paradigm Biocapital Increases Stake in Olema Pharmaceuticals
  • Increased Stake: Paradigm Biocapital Advisors acquired an additional 750,000 shares of Olema Pharmaceuticals in Q4 2025, with an estimated trade value of $13.35 million, reflecting strong confidence in the company's future.
  • Value Appreciation: The quarter-end value of Olema Pharmaceuticals' stake reached $122.09 million, representing 4.5% of Paradigm's AUM, although it remains outside the top five holdings, indicating a diversified investment strategy.
  • Strong Financial Position: Olema ended the year with over $500 million in cash and successfully raised $200 million, providing a solid financial buffer for upcoming pivotal moments in its clinical development pipeline.
  • Clinical Trial Outlook: With critical Phase 3 data expected soon, Olema's stock has surged over the past year, but any disappointing trial results could quickly reverse investor sentiment, highlighting the inherent risks in biotech investments.
Fool
8.5
03-16Fool
Cormorant Asset Management Initiates Position in Olema Pharmaceuticals
  • New Investment Move: Cormorant Asset Management initiated a position in Olema Pharmaceuticals in Q4 2026, acquiring 2.75 million shares worth $68.75 million, reflecting strong confidence in the company's future prospects.
  • Significant Holding Proportion: This investment represents 3.18% of Cormorant's 13F reportable AUM as of December 31, 2025, highlighting its importance within the fund's portfolio.
  • Outstanding Market Performance: Olema shares are currently priced at $16.60, having surged 276% over the past year, significantly outperforming the S&P 500's approximately 19% gain, indicating strong market recognition of its potential.
  • Clinical Progress Outlook: Olema's lead product OP-1250 is in Phase 1/2 clinical trials for ER-positive, HER2-negative breast cancer, and if successful, could lead to significant commercialization opportunities, with potential market entry as early as 2027.
seekingalpha
9.5
03-16seekingalpha
Olema Pharmaceuticals Q4 Earnings Beat Expectations
  • Earnings Performance: Olema Pharmaceuticals reported a Q4 GAAP EPS of -$0.50, beating market expectations of -$0.51, indicating improvements in cost management despite ongoing losses.
  • Cash Reserves: As of December 31, 2025, Olema's cash, cash equivalents, and marketable securities totaled $505.4 million, providing substantial funding for future R&D and operations, thereby enhancing financial stability.
  • Executive Departure: The departure of Olema's Chief Operating Officer and Chief Financial Officer may have short-term implications for strategic execution and financial management, necessitating close monitoring of subsequent executive appointments and their impact on operations.
  • Market Engagement: Olema actively showcased its latest developments at several key conferences, including Citi's 2026 Virtual Oncology Leadership Summit and the J.P. Morgan Healthcare Conference, indicating the company's commitment to attracting investor attention and advancing its oncology drug development pipeline.
Benzinga
7.5
03-11Benzinga
Olema Pharmaceuticals Stock Plummets Amid Clinical Trial Developments
  • Disappointing Clinical Results: Roche's phase 3 study of giredestrant combined with palbociclib failed to show a statistically significant improvement in progression-free survival compared to letrozole, leading to decreased market confidence in Olema and pressuring its stock price.
  • Optimistic Progress for Palazestrant: Olema's lead candidate, Palazestrant, is a novel oral estrogen receptor antagonist undergoing various breast cancer trials, and despite challenges, the market remains optimistic about its potential.
  • Bearish Technical Indicators: The stock is currently trading 26.2% below its 20-day SMA and 19% below its 100-day SMA, indicating a bearish trend in the short term, prompting caution among investors.
  • Price Movement Analysis: Olema shares fell 2.54% to $15.36 on Wednesday, and while the stock has surged 294.05% over the past year, it is now closer to its 52-week lows, reflecting market uncertainty.
NASDAQ.COM
8.0
03-09NASDAQ.COM
Olema Pharmaceuticals and Capital One See High Options Trading Volume
  • Olema Options Volume: Olema Pharmaceuticals Inc saw options trading volume of 6,864 contracts, equating to approximately 686,400 shares, which represents about 55.1% of its average daily trading volume of 1.2 million shares over the past month, indicating heightened market interest in its future performance.
  • High Put Option Activity: Notably, the $14 strike put option expiring on April 17, 2026, has seen 2,044 contracts traded today, representing around 204,400 underlying shares, suggesting increased investor expectations for a price decline.
  • Capital One Options Trading: Capital One Financial Corp experienced options trading volume of 27,954 contracts, translating to approximately 2.8 million shares, or about 51.7% of its average daily trading volume of 5.4 million shares over the past month, reflecting market attention on its stock volatility.
  • Active Put Option Trading: Particularly, the $220 strike put option expiring on March 20, 2026, has recorded 4,806 contracts traded today, representing about 480,600 underlying shares, indicating a cautious outlook from investors regarding Capital One's future performance.
Wall Street analysts forecast OLMA stock price to rise
11 Analyst Rating
Wall Street analysts forecast OLMA stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
42.00
High
60.00
Current: 0.000
sliders
Low
20.00
Averages
42.00
High
60.00
Wolfe Research
analyst
Peer Perform
initiated
AI Analysis
2026-03-26
New
Reason
Wolfe Research
analyst
Price Target
AI Analysis
2026-03-26
New
initiated
Peer Perform
Reason
Wolfe Research initiated coverage of Olema Oncology with a Peer Perform rating and no price target. Olema is pursuing development in second-line metastatic breast cancer and first-line mBC for lead candidate palazestrant, notes the analyst, who adds that the \"most important item to watch is if the drug shows convincing activity in both ESR1- mt and ESR1-wt\" patients.
Jefferies
Dennis Ding
NULL -> Buy
initiated
$43 -> $40
2026-03-19
Reason
Jefferies
Dennis Ding
Price Target
$43 -> $40
2026-03-19
initiated
NULL -> Buy
Reason
Jefferies analyst Dennis Ding assumed coverage of Olema Oncology with a Buy rating and price target of $40, down from $43. The firm views Olema as a "high quality" oncology company with multiple Phase III breast cancer studies for its "potent" oral CERAN plus KAT6 pipeline. The Phase I KAT6 data in Q2 could expand the oncology franchise beyond breast cancer, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Olema Pharmaceuticals Inc (OLMA.O) is -11.64, compared to its 5-year average forward P/E of -5.37. For a more detailed relative valuation and DCF analysis to assess Olema Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.37
Current PE
-11.64
Overvalued PE
-0.96
Undervalued PE
-9.79

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.20
Current EV/EBITDA
-8.30
Overvalued EV/EBITDA
1.00
Undervalued EV/EBITDA
-5.40

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
44.43
Current PS
1193.09
Overvalued PS
259.89
Undervalued PS
-171.03

Financials

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Whales Holding OLMA

V
Vivo Capital, LLC
Holding
OLMA
+7.04%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
OLMA
+6.99%
3M Return
A
Artal Group S.A.
Holding
OLMA
+1.99%
3M Return
V
Vestal Point Capital, LP
Holding
OLMA
+1.52%
3M Return
B
BVF Partners L.P.
Holding
OLMA
-2.32%
3M Return
R
RA Capital Management, L.P.
Holding
OLMA
-6.55%
3M Return

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Frequently Asked Questions

What is Olema Pharmaceuticals Inc (OLMA) stock price today?

The current price of OLMA is 13.42 USD — it has decreased -1.83

What is Olema Pharmaceuticals Inc (OLMA)'s business?

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a proprietary, orally available complete estrogen receptor (ER) antagonist (CERAN) and a selective ER degrader (SERD), in a Phase 3 clinical trial called OPERA-01. It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. In addition, it is developing OP-3136, a potent KAT6 inhibitor, in a Phase 1 clinical trial. OP-3136 is a novel, orally available small molecule that potently and selectively inhibits KAT6.

What is the price predicton of OLMA Stock?

Wall Street analysts forecast OLMA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OLMA is42.00 USD with a low forecast of 20.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Olema Pharmaceuticals Inc (OLMA)'s revenue for the last quarter?

Olema Pharmaceuticals Inc revenue for the last quarter amounts to -50.08M USD, increased 36.22

What is Olema Pharmaceuticals Inc (OLMA)'s earnings per share (EPS) for the last quarter?

Olema Pharmaceuticals Inc. EPS for the last quarter amounts to -38327000.00 USD, increased 45.82

How many employees does Olema Pharmaceuticals Inc (OLMA). have?

Olema Pharmaceuticals Inc (OLMA) has 131 emplpoyees as of March 31 2026.

What is Olema Pharmaceuticals Inc (OLMA) market cap?

Today OLMA has the market capitalization of 1.17B USD.