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OLMA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
13.200
Open
12.780
VWAP
12.99
Vol
1.61M
Mkt Cap
1.15B
Low
12.585
Amount
20.88M
EV/EBITDA(TTM)
--
Total Shares
87.35M
EV
612.21M
EV/OCF(TTM)
--
P/S(TTM)
--
Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers.
Show More

Events Timeline

(ET)
2026-05-26
07:10:00
Olema Pharmaceuticals Announces Clinical Trial Collaboration with Bayer
select
2026-05-12 (ET)
2026-05-12
07:20:00
Olema Oncology Anticipates OPERA-01 Trial Data Release
select

News

stocktwits
9.0
05-22stocktwits
Olema Pharmaceuticals Reports Promising Phase 1 Data for OP-3136
  • Significant Tumor Shrinkage: Olema Oncology reported that OP-3136 demonstrated tumor shrinkage in nearly two-thirds of evaluable patients, indicating its potential efficacy across multiple cancer types and supporting further development in metastatic breast cancer.
  • Good Safety Profile: The clinical trial showed OP-3136 had a clean safety profile with no dose-limiting toxicities or treatment-related discontinuations observed, suggesting good tolerability even at higher doses, which may provide broader treatment options for patients.
  • Dose-Related Exposure: The study indicated that OP-3136 achieved predictable, dose-related exposure, with drug levels meeting or exceeding efficacy targets at doses of 6 mg or higher, enhancing its attractiveness as a potential therapeutic option.
  • Market Sentiment Shift: Despite a 46% drop in OLMA shares since the beginning of the year, the stock surged 205% over the past 12 months, and retail investor sentiment shifted from “bearish” to “extremely bullish,” reflecting optimism about the drug's prospects.
Newsfilter
1.0
05-19Newsfilter
Olema Pharmaceuticals to Participate in Upcoming Investor Conferences
  • Investor Conference Schedule: Olema Pharmaceuticals will participate in the TD Cowen 7th Annual Oncology Innovation Summit on May 26, 2026, at 12:30 p.m. ET in a virtual fireside chat format, aiming to attract investor interest in its oncology research advancements.
  • Global Healthcare Conference Participation: The company will also attend the Jefferies Global Healthcare Conference on June 3, 2026, at 8:45 a.m. ET in New York, further showcasing its innovative therapies in breast cancer treatment.
  • Goldman Sachs Global Healthcare Conference: Olema plans to participate in the Goldman Sachs 47th Annual Global Healthcare Conference on June 9, 2026, at 3:20 p.m. ET in Miami, using this opportunity to share updates on its clinical trial progress and future strategies.
  • Clinical Trial Progress: Olema's lead product candidate, palazestrant (OP-1250), is currently in two Phase 3 clinical trials, demonstrating the company's strong R&D capabilities and market potential in breast cancer treatment.
seekingalpha
9.5
05-12seekingalpha
Olema Pharmaceuticals Q1 Earnings Beat Expectations
  • Earnings Performance: Olema Pharmaceuticals reported a Q1 GAAP EPS of -$0.52, beating expectations by $0.01, indicating a slight improvement in financial performance despite remaining in a loss position.
  • Cash Reserves: As of March 31, 2026, Olema's cash, cash equivalents, and marketable securities totaled $505.3 million, ensuring sufficient funding for future R&D and operations, thereby enhancing its financial stability.
  • Market Engagement: Olema presented at the 2026 Citi Virtual Oncology Leadership Summit and Guggenheim Securities Emerging Outlook: Biotech Summit, demonstrating the company's proactive approach to engaging with investors and industry leaders to boost market awareness and investor confidence.
  • Analyst Ratings: Seeking Alpha's Quant Rating on Olema Pharmaceuticals reflects market interest in its future performance, as current financial data still shows losses, yet investor interest in its potential growth opportunities remains strong.
Newsfilter
5.0
04-02Newsfilter
Olema Pharmaceuticals Grants Stock Options to New Employees
  • Stock Options Granted: Olema Pharmaceuticals granted stock options for a total of 188,500 shares to four new employees effective April 1, 2026, aimed at attracting and retaining talent, thereby enhancing the company's competitive edge in the biopharmaceutical sector.
  • Exercise Price: The options have an exercise price of $15.12 per share, equal to the last reported sale price on April 1, 2026, aligning the interests of new employees with those of shareholders and promoting a culture of ownership.
  • Vesting Schedule: The stock options vest over four years, with 25% vesting on the first anniversary and the remainder in 36 equal monthly installments, which is designed to improve employee retention and foster long-term stability within the company.
  • Compliance Disclosure: Olema is providing this information in accordance with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's commitment to transparency and compliance in employee incentives, which can enhance investor confidence.
Fool
6.5
03-22Fool
Paradigm Increases Stake in Olema Pharmaceuticals
  • Share Acquisition: Paradigm Biocapital Advisors LP disclosed a purchase of 750,000 shares of Olema Pharmaceuticals in Q4 2025, representing an estimated $13.35 million trade that underscores confidence in the company.
  • Increased Ownership: This acquisition raised Paradigm's stake in Olema to approximately 4.5%, highlighting its significance within the reported assets under management.
  • Outstanding Stock Performance: As of February 17, 2026, Olema shares were priced at $14.08, reflecting a staggering 242% increase over the past year, significantly outperforming the S&P 500's 15% gain, indicating strong market recognition of its potential.
  • Strong Financial Position: Olema ended the year with over $500 million in cash and successfully raised $200 million, providing ample financial support for upcoming pivotal moments in its clinical pipeline.
NASDAQ.COM
6.5
03-22NASDAQ.COM
Paradigm Biocapital Increases Stake in Olema Pharmaceuticals
  • Increased Stake: Paradigm Biocapital Advisors acquired an additional 750,000 shares of Olema Pharmaceuticals in Q4 2025, with an estimated trade value of $13.35 million, reflecting strong confidence in the company's future.
  • Value Appreciation: The quarter-end value of Olema Pharmaceuticals' stake reached $122.09 million, representing 4.5% of Paradigm's AUM, although it remains outside the top five holdings, indicating a diversified investment strategy.
  • Strong Financial Position: Olema ended the year with over $500 million in cash and successfully raised $200 million, providing a solid financial buffer for upcoming pivotal moments in its clinical development pipeline.
  • Clinical Trial Outlook: With critical Phase 3 data expected soon, Olema's stock has surged over the past year, but any disappointing trial results could quickly reverse investor sentiment, highlighting the inherent risks in biotech investments.
Wall Street analysts forecast OLMA stock price to rise
11 Analyst Rating
Wall Street analysts forecast OLMA stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
42.00
High
60.00
Current: 0.000
sliders
Low
20.00
Averages
42.00
High
60.00
Citi
Buy
maintain
$62
AI Analysis
2026-05-14
Reason
Citi
Price Target
$62
AI Analysis
2026-05-14
maintain
Buy
Reason
Citi opened an \"upside 90-day catalyst watch\" on Olema Oncology while keeping a Buy rating on the shares with a $62 price target. The company will present initial clinical results for OP-3136 at ASCO which could drive share upside, the analyst tells investors in a research note. Citi believes the results could suggest differentiation and possibly potential in indications beyond breast cancer.
Guggenheim
Buy
maintain
$38 -> $35
2026-05-13
Reason
Guggenheim
Price Target
$38 -> $35
2026-05-13
maintain
Buy
Reason
Guggenheim lowered the firm's price target on Olema Oncology (OLMA) to $35 from $38 and keeps a Buy rating on the shares. The firm, which has updated its model for expense trends, says "the key learning" from near-term monotherapy OP-3136 data at ASCO 2026 will be safety versus Pfizer's (PFE) KAT6 that reports high-dose reductions, especially due to cytopenias and dysgeusia.
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Valuation Metrics

The current forward P/E ratio for Olema Pharmaceuticals Inc (OLMA.O) is 0.00, compared to its 5-year average forward P/E of -4.97. For a more detailed relative valuation and DCF analysis to assess Olema Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.97
Current PE
0.00
Overvalued PE
-1.03
Undervalued PE
-8.90

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.93
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.99
Undervalued EV/EBITDA
-4.84

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
46.40
Current PS
33.29
Overvalued PS
254.15
Undervalued PS
-161.36

Financials

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Quarterly

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Whales Holding OLMA

L
Lightspeed Ventures, LLC
Holding
OLMA
+48.00%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
OLMA
+14.66%
3M Return
A
Artal Group S.A.
Holding
OLMA
+11.24%
3M Return
V
Vestal Point Capital, LP
Holding
OLMA
+8.81%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
OLMA
+8.52%
3M Return
L
Logos Global Management, L.P.
Holding
OLMA
+6.81%
3M Return

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Frequently Asked Questions

What is Olema Pharmaceuticals Inc (OLMA) stock price today?

The current price of OLMA is 13.19 USD — it has increased 3.37

What is Olema Pharmaceuticals Inc (OLMA)'s business?

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers.

What is the price predicton of OLMA Stock?

Wall Street analysts forecast OLMA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OLMA is42.00 USD with a low forecast of 20.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Olema Pharmaceuticals Inc (OLMA)'s revenue for the last quarter?

Olema Pharmaceuticals Inc revenue for the last quarter amounts to -57.99M USD, increased 66.28

What is Olema Pharmaceuticals Inc (OLMA)'s earnings per share (EPS) for the last quarter?

Olema Pharmaceuticals Inc. EPS for the last quarter amounts to -45987000.00 USD, increased 4.57

How many employees does Olema Pharmaceuticals Inc (OLMA). have?

Olema Pharmaceuticals Inc (OLMA) has 131 emplpoyees as of May 30 2026.

What is Olema Pharmaceuticals Inc (OLMA) market cap?

Today OLMA has the market capitalization of 1.15B USD.