Sarepta's Shares Climb Following Encouraging News on DM1 Treatment
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 25 2025
0mins
Source: NASDAQ.COM
Sarepta Therapeutics' Stock Surge: Shares of Sarepta Therapeutics rose 7% following positive updates on its phase I/II study of SRP-1003, a potential treatment for type 1 myotonic dystrophy, including successful patient enrollment and safety committee approval.
Milestone Payments and Partnerships: The announcement triggered a $200 million milestone payment to Arrowhead Pharmaceuticals, part of a multi-billion-dollar licensing deal, with Sarepta having previously made a $100 million payment earlier this year.
Investor Sentiment: Despite the stock's significant decline of nearly 85% year-to-date, investor optimism has increased due to the positive study updates, contrasting with challenges faced by other companies in the same therapeutic area.
Future Developments: Sarepta is currently dosing patients in the fourth cohort of the study and plans to begin the fifth cohort in early 2026, with initial data expected early next year for SRP-1003 and other clinical-stage programs.
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Analyst Views on SRPT
Wall Street analysts forecast SRPT stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for SRPT is 20.80 USD with a low forecast of 5.00 USD and a high forecast of 45.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
18 Analyst Rating
4 Buy
10 Hold
4 Sell
Hold
Current: 21.310
Low
5.00
Averages
20.80
High
45.00
Current: 21.310
Low
5.00
Averages
20.80
High
45.00
About SRPT
Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS. Its pipeline includes over 40 programs at various stages of discovery, pre-clinical and clinical development.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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