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PEPG Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
6.780
Open
6.230
VWAP
6.50
Vol
1.31M
Mkt Cap
464.74M
Low
5.970
Amount
8.53M
EV/EBITDA(TTM)
--
Total Shares
68.75M
EV
316.28M
EV/OCF(TTM)
--
P/S(TTM)
--
PepGen Inc. is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies. The Company’s Enhanced Delivery Oligonucleotide (EDO) platform leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake and nuclear delivery. Using these EDO peptides, the Company is generating a pipeline of oligonucleotide therapeutic candidates designed to target the root cause of serious diseases. It is focused on addressing the underlying cause of Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), which have high unmet need. Its pipeline consists of two clinical stage programs, PGN-EDO51 for DMD patients who are amenable to an exon 51-skipping approach and PGN-EDODM1 for DM1 patients, and several additional preclinical stage programs. Its product candidates also include PGN-EDO53, PGN-EDO45 and PGN-EDO44.
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Events Timeline

(ET)
2026-03-04
20:00:00
Tech Stocks Rally, Micron Up 5.5%
select
2026-03-04
16:20:00
PepGen Announces Regulatory Updates on Freedom2 Trial
select
2026-03-04
16:20:00
PepGen 2025 FREEDOM Trial Data Impresses
select
2026-03-04
16:10:00
PepGen Inc Trading Halted, News Pending
select
2025-12-08 (ET)
2025-12-08
07:30:00
PepGen Appoints Joseph Vittiglio as Chief Business and Legal Officer
select
2025-11-12 (ET)
2025-11-12
07:31:58
PepGen reveals grant of patent for PGN-EDODM1
select

News

seekingalpha
9.5
10:11 AMseekingalpha
PinnedPepGen Reports Q4 2025 Earnings Beat with Strong Cash Position
  • Earnings Beat: PepGen's Q4 2025 report reveals a GAAP EPS of -$0.27, surpassing expectations by $0.12, indicating improvements in financial management and operational efficiency.
  • Strong Cash Reserves: As of December 31, 2025, the company holds $148.5 million in cash, cash equivalents, and marketable securities, ensuring operational stability for the coming years.
  • Funding Outlook: Based on current operational plans, PepGen believes its existing cash and equivalents will sufficiently fund operations into the second half of 2027, reflecting a solid financial position.
  • Increased Market Attention: The earnings report has heightened market interest in PepGen, boosting investor confidence in its growth potential, which may positively influence the stock price.
seekingalpha
9.0
12:11 PMseekingalpha
PepGen Shares Drop After FDA Partially Halts Clinical Trial
  • FDA Clinical Hold: PepGen's PGN-EDODM1 trial targeting myotonic dystrophy type 1 faces a partial clinical hold from the FDA due to concerns over submitted pharmacology and toxicology studies, potentially impacting the company's future R&D efforts.
  • Trial Phase Impact: The hold affects the FREEDOM2-DM1 Phase 2 trial, and while the Phase 1 FREEDOM study data remains unchallenged, this decision may lead to delays in clinical progress, thereby affecting investor confidence.
  • Data Submission Commitment: PepGen has committed to submitting additional analyses to the FDA, including recently unblinded FREEDOM data, indicating the company's dedication to addressing FDA inquiries swiftly to restore trial progress and maintain market position.
  • Market Reaction: Following the FDA's announcement of the partial hold, PepGen shares continued to decline in premarket trading, reflecting market unease regarding the company's clinical trial outlook, which could negatively impact its financing and future growth.
Benzinga
9.5
11:02 AMBenzinga
Veeva Systems Reports Strong Q4 Results and Raises FY27 Guidance
  • Strong Financials: Veeva Systems reported Q4 revenue of $836 million, a 16% year-over-year increase, surpassing the market expectation of $810.6 million, indicating robust growth potential in the life sciences sector.
  • Earnings Beat: The company posted earnings per share of $2.06, exceeding the consensus estimate of $1.93, reflecting ongoing improvements in profitability and boosting investor confidence.
  • Stock Surge: Veeva Systems shares jumped 11.3% in pre-market trading to $209.81, indicating a positive market reaction to its financial performance and future outlook.
  • Optimistic Guidance: The company raised its FY27 guidance above market expectations, further solidifying its leadership position in the industry and laying a strong foundation for future growth.
Benzinga
9.0
10:03 AMBenzinga
PepGen Faces FDA Partial Hold on FREEDOM2 Trial Amid Regulatory Concerns
  • FDA Partial Hold: The U.S. FDA has placed PepGen's FREEDOM2-DM1 trial on a partial clinical hold due to concerns regarding preclinical pharmacology and toxicology studies, which may hinder the company's future clinical progress and investor confidence.
  • Shift in Research Focus: In May 2025, PepGen voluntarily discontinued the development of PGN-EDO51, redirecting its efforts towards myotonic dystrophy type 1 (DM1), a strategic shift that could impact its market positioning and allocation of R&D resources.
  • International Trial Approval: Despite facing challenges from the FDA, PepGen has received regulatory clearance to initiate the FREEDOM2 study in South Korea, Australia, and New Zealand, indicating potential for expansion in global markets.
  • Declining Stock Performance: PepGen shares fell 14.20% during premarket trading to $5.80, significantly below its 20-day and 100-day simple moving averages, reflecting a bearish outlook from the market regarding its future developments.
Newsfilter
5.0
2025-12-09Newsfilter
PepGen Appoints New Chief Business Officer with 160,000 Stock Options Grant
  • Executive Appointment: PepGen Inc. appointed Joseph Vittiglio as Chief Business and Legal Officer, granting him 160,000 non-qualified stock options under the 2024 Inducement Plan, with an exercise price of $5.59 per share, reflecting the company's commitment to strengthening its executive team.
  • Stock Option Structure: The stock options have a ten-year term and are scheduled to vest over four years, with 25% vesting on the one-year anniversary of Vittiglio's employment and the remainder vesting in equal monthly installments, aimed at incentivizing his long-term service to the company.
  • Plan Background: This grant is made under PepGen's 2024 Inducement Plan, adopted by the Board in August 2024, in accordance with Nasdaq Listing Rule 5635(c)(4), indicating the company's strategic intent to attract top talent.
  • Company Vision: PepGen is focused on advancing next-generation oligonucleotide therapies to transform the treatment of severe neuromuscular and neurological diseases, and Vittiglio's addition is expected to contribute significantly to achieving this vision.
Benzinga
2.0
2025-12-08Benzinga
Meihua International Medical Technologies, Fly-E Group, and Other Major Stocks Decline in Pre-Market Trading on Monday
  • U.S. Stock Futures: U.S. stock futures showed mixed results, with Dow futures down approximately 0.1% on Monday morning.

  • Meihua International Medical Technologies: Shares of Meihua International Medical Technologies fell 32.9% in pre-market trading after the announcement of its delisting from Nasdaq.

  • Other Notable Stock Movements: Several other stocks experienced significant declines in pre-market trading, including SMX down 17.2%, Gulf Resources down 16.1%, and Wheeler Real Estate down 16.1%.

  • Market Reactions: The market saw various stocks decline after previous gains, with Fly-E Group and Ecarx Holdings also reporting notable drops due to regulatory issues and market fluctuations.

Wall Street analysts forecast PEPG stock price to rise
2 Analyst Rating
Wall Street analysts forecast PEPG stock price to rise
1 Buy
0 Hold
1 Sell
Hold
Current: 0.000
sliders
Low
3.00
Averages
11.50
High
20.00
Current: 0.000
sliders
Low
3.00
Averages
11.50
High
20.00
Oppenheimer
Oppenheimer
Outperform
initiated
$15
AI Analysis
2026-02-25
Reason
Oppenheimer
Oppenheimer
Price Target
$15
AI Analysis
2026-02-25
initiated
Outperform
Reason
Oppenheimer initiated coverage of PepGen with an Outperform rating and $15 price target. The firm notes PepGen is a clinical-stage myotonic dystrophy type 1 company employing a cell-penetrating peptide aiming to optimize drug delivery. Despite its best-in-class efficacy in DM1, PepGen has been under pressure due to concerns that kidney adverse events observed with its Duchenne muscular dystrophy program could potentially reemerge in DM1, Oppenheimer notes. Although kidney safety is a credible risk, the firm's analysis of safety data suggests the 10mg/kg dose can balance acceptable safety with potentially best-in-class efficacy.
Guggenheim
Debjit Chattopadhyay
Buy
maintain
$6 -> $7
2026-02-18
Reason
Guggenheim
Debjit Chattopadhyay
Price Target
$6 -> $7
2026-02-18
maintain
Buy
Reason
Guggenheim analyst Debjit Chattopadhyay raised the firm's price target on PepGen to $7 from $6 and keeps a Buy rating on the shares. The firm, which anticipates data from the FREEDOM2 5 mg/kg MAD cohort in March, cites its analysis of the FREEDOM2 outlook for increasing its price target, noting that its base case scenario assumes SI correction in the high teens.
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Valuation Metrics

The current forward P/E ratio for PepGen Inc (PEPG.O) is -5.20, compared to its 5-year average forward P/E of -2.70. For a more detailed relative valuation and DCF analysis to assess PepGen Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.70
Current PE
-5.20
Overvalued PE
-1.17
Undervalued PE
-4.23

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.37
Current EV/EBITDA
-3.35
Overvalued EV/EBITDA
0.17
Undervalued EV/EBITDA
-2.91

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding PEPG

B
BVF Partners L.P.
Holding
PEPG
+16.29%
3M Return
V
Vivo Capital, LLC
Holding
PEPG
+11.68%
3M Return
R
RA Capital Management, L.P.
Holding
PEPG
+8.53%
3M Return
C
Commodore Capital LP
Holding
PEPG
+7.07%
3M Return
Q
Qatar Holding LLC
Holding
PEPG
-3.41%
3M Return

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Frequently Asked Questions

What is PepGen Inc (PEPG) stock price today?

The current price of PEPG is 6.76 USD — it has increased 5.3

What is PepGen Inc (PEPG)'s business?

PepGen Inc. is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies. The Company’s Enhanced Delivery Oligonucleotide (EDO) platform leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake and nuclear delivery. Using these EDO peptides, the Company is generating a pipeline of oligonucleotide therapeutic candidates designed to target the root cause of serious diseases. It is focused on addressing the underlying cause of Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), which have high unmet need. Its pipeline consists of two clinical stage programs, PGN-EDO51 for DMD patients who are amenable to an exon 51-skipping approach and PGN-EDODM1 for DM1 patients, and several additional preclinical stage programs. Its product candidates also include PGN-EDO53, PGN-EDO45 and PGN-EDO44.

What is the price predicton of PEPG Stock?

Wall Street analysts forecast PEPG stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PEPG is11.50 USD with a low forecast of 3.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PepGen Inc (PEPG)'s revenue for the last quarter?

PepGen Inc revenue for the last quarter amounts to -18.65M USD, decreased -19.49

What is PepGen Inc (PEPG)'s earnings per share (EPS) for the last quarter?

PepGen Inc. EPS for the last quarter amounts to -19356000.00 USD, decreased -20.01

How many employees does PepGen Inc (PEPG). have?

PepGen Inc (PEPG) has 81 emplpoyees as of March 05 2026.

What is PepGen Inc (PEPG) market cap?

Today PEPG has the market capitalization of 464.74M USD.