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PEPG Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.775
Open
1.720
VWAP
1.72
Vol
939.16K
Mkt Cap
117.50M
Low
1.687
Amount
1.62M
EV/EBITDA(TTM)
--
Total Shares
69.12M
EV
-30.96M
EV/OCF(TTM)
--
P/S(TTM)
--
PepGen Inc. is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies. The Company’s Enhanced Delivery Oligonucleotide (EDO) platform leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake and nuclear delivery. Using these EDO peptides, the Company is generating a pipeline of oligonucleotide therapeutic candidates designed to target the root cause of serious diseases. It is focused on addressing the underlying cause of Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), which have high unmet need. Its pipeline consists of two clinical stage programs, PGN-EDO51 for DMD patients who are amenable to an exon 51-skipping approach and PGN-EDODM1 for DM1 patients, and several additional preclinical stage programs. Its product candidates also include PGN-EDO53, PGN-EDO45 and PGN-EDO44.
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Events Timeline

(ET)
2026-03-30
18:40:00
Investor Sentiment Affected by Middle East, S&P 500 Declines 0.4%
select
2026-03-30
18:00:00
PepGen Shares Drop 46% to $2.30 After Phase 2 Freedom Trial Data
select
2026-03-30
16:20:00
PepGen Reports Promising Clinical Data from DM1 Trial
select
2026-03-30
16:10:00
PepGen Inc Trading Halted, News Pending
select
2026-03-05 (ET)
2026-03-05
16:30:00
Stocks Fall as Middle East War Escalates, S&P 500 Drops Over 0.5%
select
2026-03-05
12:10:00
Stocks Lower at Midday as Oil Prices Hit New Highs
select
2026-03-04 (ET)
2026-03-04
20:00:00
Tech Stocks Rally, Micron Up 5.5%
select

News

Globenewswire
7.0
04-14Globenewswire
PepGen Under Investigation for Securities Fraud Claims
  • Securities Fraud Investigation: Pomerantz LLP is investigating PepGen Inc. for potential securities fraud involving its officers, which could undermine investor confidence and lead to stock price volatility.
  • Partial Clinical Hold: On March 4, 2026, PepGen announced that the FDA placed a partial hold on its PGN-EDODM1 clinical trial, raising concerns about previously submitted pharmacology and toxicology studies, potentially impacting future R&D progress.
  • Significant Stock Price Drop: Following the FDA announcement, PepGen's stock fell by $1.25, or 18.57%, to close at $5.50 on March 5, 2026, reflecting market concerns about the company's outlook.
  • Lack of Meaningful Improvement: On March 30, 2026, PepGen's clinical data was criticized by analysts for not showing significant improvements in patients' handgrip strength or 10-meter walk/run tests, leading to a further stock decline of $2.46, or 58.16%, to $1.77 on March 31, 2026.
PRnewswire
2.0
04-03PRnewswire
PepGen Under Investigation for Securities Fraud Claims
  • Securities Fraud Investigation: Pomerantz LLP is investigating claims on behalf of PepGen Inc. investors regarding potential securities fraud or unlawful business practices, indicating serious concerns about corporate governance and accountability.
  • Partial Clinical Hold: On March 4, 2026, PepGen announced that the FDA placed a partial clinical hold on its PGN-EDODM1 trial, raising questions about previously submitted pharmacology and toxicology studies, which significantly undermined investor confidence.
  • Significant Stock Price Drop: Following the FDA announcement, PepGen's stock price fell by $1.25, or 18.57%, closing at $5.50 on March 5, 2026, reflecting a pessimistic outlook from the market regarding the company's future prospects.
  • Lack of Meaningful Improvement: Although PepGen characterized the clinical data released on March 30, 2026, as
PRnewswire
7.0
04-02PRnewswire
PepGen Under Investigation for Securities Fraud Claims
  • Investigation Launched: Pomerantz LLP is investigating claims on behalf of PepGen Inc. investors regarding potential securities fraud or other unlawful business practices, highlighting serious concerns about corporate governance and compliance.
  • Clinical Trial Halted: On March 4, 2026, PepGen announced that the FDA placed a partial clinical hold on its PGN-EDODM1 trial, raising questions related to previously submitted pharmacology and toxicology studies, which could impact the company's future R&D efforts.
  • Stock Price Plummets: Following the FDA announcement, PepGen's stock price fell by $1.25, or 18.57%, closing at $5.50 per share on March 5, 2026, reflecting market pessimism regarding the company's outlook.
  • Potential Legal Consequences: The investigation may lead to class action lawsuits against PepGen, further affecting its reputation and financial standing, prompting investors to closely monitor developments to assess potential risks.
Globenewswire
7.0
03-31Globenewswire
PepGen Faces Investigation Over Securities Law Violations
  • FDA Clinical Hold: On March 4, 2026, PepGen disclosed that the FDA imposed a partial clinical hold on its PGN-EDODM1 FREEDOM2-DM1 trial due to concerns regarding previously submitted pharmacology and toxicology studies, which could hinder the company's future research and development efforts and erode market confidence.
  • Sharp Stock Decline: Following the additional clinical data release on March 30, 2026, PepGen's stock price plummeted in after-hours trading, exacerbating investor losses and indicating a lack of market confidence in the company's clinical progress and future prospects.
  • Investor Rights Investigation: Johnson Fistel, PLLP is investigating whether PepGen violated federal securities laws, urging investors who suffered losses from holding PepGen stock to join the investigation, which may provide legal support and compensation opportunities for affected investors.
  • Law Firm Background: Johnson Fistel, PLLP is a nationally recognized shareholder rights law firm, ranked among the Top 10 Plaintiff Law Firms in 2024, having recovered approximately $90.725 million for clients, showcasing its strong capabilities and influence in securities litigation.
seekingalpha
9.0
03-31seekingalpha
PepGen Shares Plunge 44% After Mixed Mid-Stage Trial Results
  • Disappointing Trial Results: PepGen (PEPG) shares plummeted approximately 44% in after-hours trading following the mid-stage trial results for its lead treatment PGN-EDODM1, which showed no significant improvements in handgrip strength or 10-meter walk/run tests at the 5 mg/kg dose cohort.
  • Ongoing Research Plans: Despite the disappointing results, the company plans to continue studying the 10 mg/kg dose cohort, with data expected in H2 2026, indicating the company's ongoing confidence in the drug's potential.
  • Divergent Analyst Opinions: While Leerink Partners analyst Joseph Schwartz highlighted the mixed nature of the data, Oppenheimer's Kostas Biliouris argued that the selloff was overdone, maintaining that PGN-EDODM1 still shows positive drug effects and may yield better results at higher doses.
  • Market Reaction Analysis: Despite some analysts' optimism regarding the drug, PepGen's stock remains under pressure due to a partial FDA hold on the mid-stage trial, reflecting market sensitivity to clinical data and concerns about the company's future prospects.
stocktwits
9.5
03-31stocktwits
PEPG, SGMO, and PHR Shares Decline Amid Disappointing Results
  • PEPG Trial Disappointment: PepGen's Phase 2 Freedom 2 study results showed no significant improvements in walking speed or hand strength at the starting dose of 5 mg/kg, leading to a 45% plunge in premarket trading, reflecting investor disappointment in the therapy's efficacy.
  • SGMO Earnings Miss: Sangamo Therapeutics reported a Q4 loss per share of $0.11, wider than the expected $0.05 loss, despite revenue rising to $14.23 million, indicating pressure on the company's funding outlook that may impact future operations.
  • PHR Revenue Outlook Cut: Phreesia lowered its fiscal 2027 revenue outlook to $510 million to $520 million, below analyst expectations of $552.1 million, resulting in a 27% drop in share price and prompting downgrades from multiple brokerages.
  • Market Sentiment Fluctuates: While retail sentiment for PEPG, SGMO, and PHR on Stocktwits was 'extremely bullish', the disappointing performance and unclear outlook have severely undermined investor confidence, reflecting a cautious attitude towards biotech stocks.
Wall Street analysts forecast PEPG stock price to rise
2 Analyst Rating
Wall Street analysts forecast PEPG stock price to rise
1 Buy
0 Hold
1 Sell
Hold
Current: 0.000
sliders
Low
3.00
Averages
11.50
High
20.00
Current: 0.000
sliders
Low
3.00
Averages
11.50
High
20.00
Oppenheimer
Oppenheimer
Outperform
initiated
$15
AI Analysis
2026-02-25
Reason
Oppenheimer
Oppenheimer
Price Target
$15
AI Analysis
2026-02-25
initiated
Outperform
Reason
Oppenheimer initiated coverage of PepGen with an Outperform rating and $15 price target. The firm notes PepGen is a clinical-stage myotonic dystrophy type 1 company employing a cell-penetrating peptide aiming to optimize drug delivery. Despite its best-in-class efficacy in DM1, PepGen has been under pressure due to concerns that kidney adverse events observed with its Duchenne muscular dystrophy program could potentially reemerge in DM1, Oppenheimer notes. Although kidney safety is a credible risk, the firm's analysis of safety data suggests the 10mg/kg dose can balance acceptable safety with potentially best-in-class efficacy.
Guggenheim
Debjit Chattopadhyay
Buy
maintain
$6 -> $7
2026-02-18
Reason
Guggenheim
Debjit Chattopadhyay
Price Target
$6 -> $7
2026-02-18
maintain
Buy
Reason
Guggenheim analyst Debjit Chattopadhyay raised the firm's price target on PepGen to $7 from $6 and keeps a Buy rating on the shares. The firm, which anticipates data from the FREEDOM2 5 mg/kg MAD cohort in March, cites its analysis of the FREEDOM2 outlook for increasing its price target, noting that its base case scenario assumes SI correction in the high teens.
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Valuation Metrics

The current forward P/E ratio for PepGen Inc (PEPG.O) is 0.00, compared to its 5-year average forward P/E of -2.70. For a more detailed relative valuation and DCF analysis to assess PepGen Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.70
Current PE
0.00
Overvalued PE
-1.17
Undervalued PE
-4.22

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.37
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.17
Undervalued EV/EBITDA
-2.91

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Whales Holding PEPG

C
Commodore Capital LP
Holding
PEPG
+32.74%
3M Return
V
Vivo Capital, LLC
Holding
PEPG
+19.07%
3M Return
B
BVF Partners L.P.
Holding
PEPG
+7.82%
3M Return
R
RA Capital Management, L.P.
Holding
PEPG
+7.21%
3M Return
Q
Qatar Holding LLC
Holding
PEPG
+0.47%
3M Return

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Frequently Asked Questions

What is PepGen Inc (PEPG) stock price today?

The current price of PEPG is 1.7 USD — it has increased 1.8

What is PepGen Inc (PEPG)'s business?

PepGen Inc. is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies. The Company’s Enhanced Delivery Oligonucleotide (EDO) platform leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake and nuclear delivery. Using these EDO peptides, the Company is generating a pipeline of oligonucleotide therapeutic candidates designed to target the root cause of serious diseases. It is focused on addressing the underlying cause of Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), which have high unmet need. Its pipeline consists of two clinical stage programs, PGN-EDO51 for DMD patients who are amenable to an exon 51-skipping approach and PGN-EDODM1 for DM1 patients, and several additional preclinical stage programs. Its product candidates also include PGN-EDO53, PGN-EDO45 and PGN-EDO44.

What is the price predicton of PEPG Stock?

Wall Street analysts forecast PEPG stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PEPG is11.50 USD with a low forecast of 3.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PepGen Inc (PEPG)'s revenue for the last quarter?

PepGen Inc revenue for the last quarter amounts to -19.70M USD, decreased -19.06

What is PepGen Inc (PEPG)'s earnings per share (EPS) for the last quarter?

PepGen Inc. EPS for the last quarter amounts to -15845000.00 USD, decreased -19.58

How many employees does PepGen Inc (PEPG). have?

PepGen Inc (PEPG) has 56 emplpoyees as of April 20 2026.

What is PepGen Inc (PEPG) market cap?

Today PEPG has the market capitalization of 117.50M USD.