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DYN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
17.880
Open
17.480
VWAP
17.60
Vol
1.74M
Mkt Cap
2.91B
Low
17.320
Amount
30.66M
EV/EBITDA(TTM)
--
Total Shares
165.22M
EV
1.95B
EV/OCF(TTM)
--
P/S(TTM)
--
Dyne Therapeutics, Inc. is a clinical-stage neuromuscular disease company. It is discovering and advancing therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE platform, it is developing targeted therapeutics that deliver to muscle and central nervous system (CNS). It has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 and Duchenne muscular dystrophy and preclinical programs for facioscapulohumeral muscular dystrophy and Pompe disease. Its product candidate, zeleciment basivarsen (also known as DYNE-101), is being evaluated in ACHIEVE, an ongoing Phase I/II global clinical trial in patients with DM1. Its product candidate, zeleciment rostudirsen (also known as DYNE-251), is being evaluated in DELIVER, an ongoing Phase I/II global clinical trial in patients with DMD who have mutations amenable to skipping exon 51. Its other product candidates are DYNE-302 and DYNE-401.
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Events Timeline

(ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
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2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
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link
2026-03-08 (ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
18:10:00
Dyne Therapeutics Initiates Phase 3 Harmonia Trial
select
2026-03-08
18:10:00
Dyne Therapeutics Releases Positive Data from DMD Clinical Trial
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2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
select
link
2026-03-02 (ET)
2026-03-02
07:41:00
Dyne Plans to Launch New Therapy in DMD Field
select

News

Newsfilter
8.5
11:43 AMNewsfilter
PinnedDyne Therapeutics Reports Positive FDA Meeting Progress
  • FDA Meeting Outcomes: Dyne Therapeutics successfully completed a pre-BLA meeting with the FDA, aligning on the planned BLA submission for z-rostudirsen in Q2 2026, with a potential launch in Q1 2027, indicating strong progress in DMD treatment development.
  • Clinical Trial Progress: In the ACHIEVE trial for DM1, Dyne has reached its target of 60 participants in the registrational expansion cohort, with expectations to exceed this target by completing enrollment in Q2 2026, further advancing the clinical development of z-basivarsen.
  • DELIVER Trial Results: At the 2026 MDA conference, Dyne presented positive results for z-rostudirsen, showing significant improvements in cardiopulmonary function and long-term dystrophin production, with muscle content-adjusted dystrophin reaching an average of 18.33% of normal.
  • Strong Financial Position: As of March 31, 2026, Dyne reported cash and cash equivalents of $972.2 million, expected to fund operations into Q1 2028, and while R&D expenses decreased, the company remains focused on preparing for the potential launch of z-rostudirsen.
Newsfilter
3.5
04-27Newsfilter
Dyne Therapeutics Presents New Data on FORCE Platform's CNS Delivery
  • FORCE Platform Breakthrough: Dyne Therapeutics presented new preclinical data at the 2026 ASGCT Annual Meeting, demonstrating the FORCE platform's ability to cross the blood-brain barrier and achieve approximately 75% MAPT RNA knockdown in the central nervous system, highlighting its potential in treating neurological diseases.
  • Clinical Application Expansion: The platform not only focuses on Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) but also explores treatment possibilities for other neurological diseases, indicating Dyne's commitment to developing potentially transformative therapies while advancing its clinical programs.
  • Optimized Delivery Mechanism: By further optimizing the FORCE platform, Dyne showcased a modified TfR1-binding antibody fragment (Fab) that achieved widespread MAPT RNA knockdown across brain regions in mice and nonhuman primates, enhancing CNS drug delivery capabilities and potentially offering new treatments for tauopathies like Alzheimer's disease.
  • Future Development Directions: Dyne is evaluating next steps for the preclinical development of these conjugates with the goal of maintaining capital efficiency and maximizing shareholder value, demonstrating the company's strategic balance between innovation and market demand.
Newsfilter
8.5
04-01Newsfilter
Dyne Therapeutics Presents Clinical Trial Posters on DMD and DM1 at AMCP 2026
  • Clinical Trial Results Presentation: Dyne Therapeutics will present three posters on Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) at the 2026 AMCP Annual Conference, emphasizing functional improvement data from the DELIVER and ACHIEVE trials to provide managed care experts with clinical context, thereby facilitating future treatment accessibility.
  • Market Opportunity: Dyne anticipates a potential DMD treatment launch in the U.S. in 2027, followed by DM1 in 2028, indicating the company's keen insight into market demand and proactive engagement with payers to ensure patient access to effective therapies.
  • Educational Symposium Support: Dyne is also supporting a continuing education symposium for managed care professionals titled “High-Stakes Access: Aligning Managed Care Policy with the Urgency of Treatment in Duchenne Muscular Dystrophy,” reflecting the company's active involvement in advocating for policy changes.
  • Collaboration and Research: The DM1 health insurance and literacy poster developed in collaboration with the Myotonic Dystrophy Foundation showcases Dyne's collaborative efforts in study design and result interpretation, aiming to ensure that patient needs are reflected in healthcare decision-making.
Yahoo Finance
9.5
03-11Yahoo Finance
Dyne Therapeutics Shares Surge 11.81% on Buy Rating
  • Stock Surge: Dyne Therapeutics saw its share price jump by 11.81% on Tuesday, closing at $19.78 per share, reflecting market optimism about its future performance, particularly after an investment firm reiterated a triple-digit upside potential for its stock.
  • Buy Rating Reaffirmed: Jefferies reiterated its 'buy' rating for Dyne Therapeutics, setting a price target of $50, which represents a 153% upside from the latest closing price, indicating strong confidence in the accelerated approval of its therapy candidate.
  • Clinical Trial Advancement: Dyne Therapeutics announced the official initiation of the third phase of its trial for DM1, planning to enroll 150 participants aged 16 and above to assess the efficacy of zeleciment basivarsen, further validating its best-in-class potential in muscle systems and the CNS.
  • Study Design: The Harmonia trial will utilize a clinically meaningful functional measure as the primary endpoint, aiming to evaluate improvements in the 'sit-to-stand' test after 49 weeks, designed to reinforce the therapeutic potential of z-basivarsen across a broad range of muscle systems.
Benzinga
9.5
03-10Benzinga
U.S. Stocks Rise as NIO Reports Strong Earnings
  • Quarterly Revenue Surge: NIO reported quarterly revenue of 34.65 billion yuan ($4.95 billion), reflecting a year-over-year increase of 75.9% and a sequential rise of 59.0%, surpassing the analyst consensus estimate of $4.61 billion, indicating robust market demand and sales growth potential.
  • Significant Earnings Improvement: The company's adjusted earnings came in at 0.29 yuan (4 cents) per ADS, a remarkable turnaround from a loss of 3.17 yuan per ADS a year earlier, exceeding expectations for a 5-cent loss, showcasing effective cost control and enhanced profitability.
  • Stock Price Rally: Following the earnings report, NIO shares surged 10.6% to $5.47, reflecting investor optimism regarding the company's future growth prospects and potentially attracting more institutional investor interest.
  • Overall Market Performance: The U.S. stock market rose overall, with the Dow Jones index gaining around 200 points on Tuesday, indicating increased confidence in economic recovery, which may provide a favorable investment environment for NIO and other tech stocks.
Benzinga
9.5
03-09Benzinga
Relmada Therapeutics Shares Surge 40.8% on Promising Trial Data
  • Market Decline: U.S. stocks fell broadly on Monday, with the Dow Jones index dropping around 650 points, indicating investor concerns about economic outlook which may impact consumer spending and overall market confidence.
  • Relmada Stock Surge: Shares of Relmada Therapeutics Inc. soared 40.8% to $6.27 during Monday's session, driven by the release of promising interim data from its Phase 2 trial of NDV-01 for treating non-muscle invasive bladder cancer.
  • Clinical Trial Results: The 12-month interim data revealed a complete response rate of 76%, with an impressive 80% in the BCG-unresponsive patient population, providing strong support for Relmada's treatment approach and potentially enhancing market acceptance.
  • Positive Market Reaction: The favorable feedback from clinical data has led to optimistic investor sentiment regarding Relmada's future prospects, not only boosting the company's stock price but also likely attracting more investor interest in its ongoing research and development efforts.
Wall Street analysts forecast DYN stock price to rise
9 Analyst Rating
Wall Street analysts forecast DYN stock price to rise
7 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
17.00
Averages
39.33
High
60.00
Current: 0.000
sliders
Low
17.00
Averages
39.33
High
60.00
Morgan Stanley
Overweight
downgrade
$50 -> $47
AI Analysis
2026-03-03
Reason
Morgan Stanley
Price Target
$50 -> $47
AI Analysis
2026-03-03
downgrade
Overweight
Reason
Morgan Stanley lowered the firm's price target on Dyne Therapeutics to $47 from $50 and keeps an Overweight rating on the shares. The firm, which notes that timelines for lead programs in DMD and DM1 remain on track, views 2026 as "a year of execution."
H.C. Wainwright
Buy
downgrade
$60 -> $50
2026-03-03
Reason
H.C. Wainwright
Price Target
$60 -> $50
2026-03-03
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Dyne Therapeutics to $50 from $60 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DYN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Dyne Therapeutics, Inc (DYN.O) is 0.00, compared to its 5-year average forward P/E of -5.21. For a more detailed relative valuation and DCF analysis to assess Dyne Therapeutics, Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.21
Current PE
0.00
Overvalued PE
-2.03
Undervalued PE
-8.39

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.59
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.55
Undervalued EV/EBITDA
-6.63

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2.87
Current PS
41.51
Overvalued PS
13.39
Undervalued PS
-7.66

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Whales Holding DYN

B
Bluebox Asset Management Uk Ltd.
Holding
DYN
+20.01%
3M Return
V
VR Management, LLC
Holding
DYN
+18.39%
3M Return
B
Braidwell LP
Holding
DYN
+17.70%
3M Return
P
Perceptive Advisors LLC
Holding
DYN
+16.35%
3M Return
A
Artal Group S.A.
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+14.33%
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TCG Crossover Management, LLC
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Frequently Asked Questions

What is Dyne Therapeutics, Inc (DYN) stock price today?

The current price of DYN is 17.61 USD — it has increased 0.4

What is Dyne Therapeutics, Inc (DYN)'s business?

Dyne Therapeutics, Inc. is a clinical-stage neuromuscular disease company. It is discovering and advancing therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE platform, it is developing targeted therapeutics that deliver to muscle and central nervous system (CNS). It has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 and Duchenne muscular dystrophy and preclinical programs for facioscapulohumeral muscular dystrophy and Pompe disease. Its product candidate, zeleciment basivarsen (also known as DYNE-101), is being evaluated in ACHIEVE, an ongoing Phase I/II global clinical trial in patients with DM1. Its product candidate, zeleciment rostudirsen (also known as DYNE-251), is being evaluated in DELIVER, an ongoing Phase I/II global clinical trial in patients with DMD who have mutations amenable to skipping exon 51. Its other product candidates are DYNE-302 and DYNE-401.

What is the price predicton of DYN Stock?

Wall Street analysts forecast DYN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DYN is39.33 USD with a low forecast of 17.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Dyne Therapeutics, Inc (DYN)'s revenue for the last quarter?

Dyne Therapeutics, Inc revenue for the last quarter amounts to -116.13M USD, increased 19.59

What is Dyne Therapeutics, Inc (DYN)'s earnings per share (EPS) for the last quarter?

Dyne Therapeutics, Inc. EPS for the last quarter amounts to -112316000.00 USD, increased 31.50

How many employees does Dyne Therapeutics, Inc (DYN). have?

Dyne Therapeutics, Inc (DYN) has 258 emplpoyees as of May 11 2026.

What is Dyne Therapeutics, Inc (DYN) market cap?

Today DYN has the market capitalization of 2.91B USD.