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DYN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
18.500
Open
17.705
VWAP
18.05
Vol
2.21M
Mkt Cap
2.99B
Low
17.515
Amount
39.80M
EV/EBITDA(TTM)
--
Total Shares
165.03M
EV
1.86B
EV/OCF(TTM)
--
P/S(TTM)
--
Dyne Therapeutics, Inc. is a clinical-stage neuromuscular disease company. It is discovering and advancing therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE platform, it is developing targeted therapeutics that deliver to muscle and central nervous system (CNS). It has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 and Duchenne muscular dystrophy and preclinical programs for facioscapulohumeral muscular dystrophy and Pompe disease. Its product candidate, zeleciment basivarsen (also known as DYNE-101), is being evaluated in ACHIEVE, an ongoing Phase I/II global clinical trial in patients with DM1. Its product candidate, zeleciment rostudirsen (also known as DYNE-251), is being evaluated in DELIVER, an ongoing Phase I/II global clinical trial in patients with DMD who have mutations amenable to skipping exon 51. Its other product candidates are DYNE-302 and DYNE-401.
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Events Timeline

(ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
18:10:00
Dyne Therapeutics Releases Positive Data from DMD Clinical Trial
select
2026-03-08
18:10:00
Dyne Therapeutics Initiates Phase 3 Harmonia Trial
select
2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
select
link
2026-03-02 (ET)
2026-03-02
07:41:00
Dyne Plans to Launch New Therapy in DMD Field
select
2026-01-20 (ET)
2026-01-20
07:40:00
Dyne Therapeutics Receives Orphan Drug Designation in Japan
select

News

Yahoo Finance
9.5
03-11Yahoo Finance
Dyne Therapeutics Shares Surge 11.81% on Buy Rating
  • Stock Surge: Dyne Therapeutics saw its share price jump by 11.81% on Tuesday, closing at $19.78 per share, reflecting market optimism about its future performance, particularly after an investment firm reiterated a triple-digit upside potential for its stock.
  • Buy Rating Reaffirmed: Jefferies reiterated its 'buy' rating for Dyne Therapeutics, setting a price target of $50, which represents a 153% upside from the latest closing price, indicating strong confidence in the accelerated approval of its therapy candidate.
  • Clinical Trial Advancement: Dyne Therapeutics announced the official initiation of the third phase of its trial for DM1, planning to enroll 150 participants aged 16 and above to assess the efficacy of zeleciment basivarsen, further validating its best-in-class potential in muscle systems and the CNS.
  • Study Design: The Harmonia trial will utilize a clinically meaningful functional measure as the primary endpoint, aiming to evaluate improvements in the 'sit-to-stand' test after 49 weeks, designed to reinforce the therapeutic potential of z-basivarsen across a broad range of muscle systems.
Benzinga
9.5
03-10Benzinga
U.S. Stocks Rise as NIO Reports Strong Earnings
  • Quarterly Revenue Surge: NIO reported quarterly revenue of 34.65 billion yuan ($4.95 billion), reflecting a year-over-year increase of 75.9% and a sequential rise of 59.0%, surpassing the analyst consensus estimate of $4.61 billion, indicating robust market demand and sales growth potential.
  • Significant Earnings Improvement: The company's adjusted earnings came in at 0.29 yuan (4 cents) per ADS, a remarkable turnaround from a loss of 3.17 yuan per ADS a year earlier, exceeding expectations for a 5-cent loss, showcasing effective cost control and enhanced profitability.
  • Stock Price Rally: Following the earnings report, NIO shares surged 10.6% to $5.47, reflecting investor optimism regarding the company's future growth prospects and potentially attracting more institutional investor interest.
  • Overall Market Performance: The U.S. stock market rose overall, with the Dow Jones index gaining around 200 points on Tuesday, indicating increased confidence in economic recovery, which may provide a favorable investment environment for NIO and other tech stocks.
Benzinga
9.5
03-09Benzinga
Relmada Therapeutics Shares Surge 40.8% on Promising Trial Data
  • Market Decline: U.S. stocks fell broadly on Monday, with the Dow Jones index dropping around 650 points, indicating investor concerns about economic outlook which may impact consumer spending and overall market confidence.
  • Relmada Stock Surge: Shares of Relmada Therapeutics Inc. soared 40.8% to $6.27 during Monday's session, driven by the release of promising interim data from its Phase 2 trial of NDV-01 for treating non-muscle invasive bladder cancer.
  • Clinical Trial Results: The 12-month interim data revealed a complete response rate of 76%, with an impressive 80% in the BCG-unresponsive patient population, providing strong support for Relmada's treatment approach and potentially enhancing market acceptance.
  • Positive Market Reaction: The favorable feedback from clinical data has led to optimistic investor sentiment regarding Relmada's future prospects, not only boosting the company's stock price but also likely attracting more investor interest in its ongoing research and development efforts.
NASDAQ.COM
2.0
03-09NASDAQ.COM
Dyne Therapeutics Announces Major Clinical Updates on DMD and DM1 Trials
  • Positive DELIVER Results: Dyne Therapeutics' DELIVER trial for DMD shows that z-rostudirsen (DYNE-251) leads to sustained improvements in cardiopulmonary function over 24 months, surpassing expected declines from natural history data, indicating its therapeutic potential across muscle systems including the heart and diaphragm.
  • BLA Submission Plans: Dyne plans to submit a Biologics License Application (BLA) in Q2 2026, with a potential U.S. launch in Q1 2027, contingent on FDA priority review and approval, which could significantly enhance the company's market position.
  • HARMONIA Trial Initiation: The company has initiated the Phase 3 HARMONIA trial for DM1 with z-basivarsen (DYNE-101), enrolling approximately 150 participants over 48 weeks, primarily assessing the 5x sit-to-stand test, aimed at supporting traditional approval in the U.S. and ex-U.S. markets.
  • MDA Conference Presentation: Dyne will present new cardiopulmonary results and updates on the HARMONIA trial at the Muscular Dystrophy Association (MDA) conference on March 11, 2026, further enhancing its visibility and influence in the neuromuscular disease sector.
Newsfilter
2.0
03-08Newsfilter
Dyne Therapeutics Initiates Phase 3 HARMONIA Trial for DM1
  • Trial Scale and Design: The HARMONIA Phase 3 trial will enroll approximately 150 participants aged 16 and older with myotonic dystrophy type 1 (DM1), utilizing a randomized, double-blind, placebo-controlled design aimed at assessing the multi-system efficacy, safety, and tolerability of z-basivarsen, which is expected to provide confirmatory data for traditional approval in the U.S.
  • Primary Endpoint and Assessment Metrics: The primary endpoint is the change from baseline in the five times sit to stand (5xSTS) test at week 49, a reliable measure reflecting key areas of DM1 impairment, including lower extremity strength, balance, and trunk strength, which are critical for daily activities, alongside assessments of muscle function and CNS impact.
  • FDA Alignment and Market Potential: Dyne Therapeutics has aligned with the FDA on the HARMONIA trial design, with results expected to support the conversion of z-basivarsen's Accelerated Approval to traditional approval in the U.S. and lay the groundwork for international marketing applications, indicating significant global market potential.
  • Long-Term Extension Study: Following the 48-week double-blind placebo-controlled treatment period, patients will have the option to enter a 24-week long-term extension study where all participants will receive z-basivarsen, a design that not only aids in ongoing efficacy evaluation but may also enhance patient adherence and long-term health outcomes.
CNBC
9.0
03-06CNBC
FDA Rejects Multiple Experimental Drug Applications, Raising Investor Concerns
  • FDA Drug Rejections: The U.S. FDA has denied or discouraged applications for at least eight drugs over the past year, including UniQure's gene therapy for Huntington's disease, indicating regulatory uncertainty that could impact future treatment approvals.
  • Investor Concerns Rise: Investors are increasingly wary as the FDA appears to change its standards for drug applications, particularly for treatments targeting hard-to-treat diseases, leading to diminished confidence in ongoing development efforts.
  • Changing Regulatory Standards: The FDA's request for UniQure to conduct new placebo-controlled trials contradicts previous guidance, highlighting inconsistencies in the agency's approval process that may create uncertainty for companies in their R&D efforts.
  • Uncertain Future Outlook: Analysts warn that if the FDA does not approve Denali Therapeutics' drug for Hunter syndrome, it could further undermine other companies' confidence in running open-label studies, potentially stifling innovation across the industry.
Wall Street analysts forecast DYN stock price to rise
9 Analyst Rating
Wall Street analysts forecast DYN stock price to rise
7 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
17.00
Averages
39.33
High
60.00
Current: 0.000
sliders
Low
17.00
Averages
39.33
High
60.00
Morgan Stanley
Overweight
downgrade
$50 -> $47
AI Analysis
2026-03-03
Reason
Morgan Stanley
Price Target
$50 -> $47
AI Analysis
2026-03-03
downgrade
Overweight
Reason
Morgan Stanley lowered the firm's price target on Dyne Therapeutics to $47 from $50 and keeps an Overweight rating on the shares. The firm, which notes that timelines for lead programs in DMD and DM1 remain on track, views 2026 as "a year of execution."
H.C. Wainwright
Buy
downgrade
$60 -> $50
2026-03-03
Reason
H.C. Wainwright
Price Target
$60 -> $50
2026-03-03
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Dyne Therapeutics to $50 from $60 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DYN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Dyne Therapeutics, Inc (DYN.O) is -5.65, compared to its 5-year average forward P/E of -5.25. For a more detailed relative valuation and DCF analysis to assess Dyne Therapeutics, Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.25
Current PE
-5.65
Overvalued PE
-2.10
Undervalued PE
-8.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.61
Current EV/EBITDA
-4.98
Overvalued EV/EBITDA
-0.61
Undervalued EV/EBITDA
-6.62

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Whales Holding DYN

V
VR Management, LLC
Holding
DYN
+15.49%
3M Return
V
Vivo Capital, LLC
Holding
DYN
+14.23%
3M Return
A
Artal Group S.A.
Holding
DYN
+11.60%
3M Return
P
Perceptive Advisors LLC
Holding
DYN
+8.68%
3M Return
T
TCG Crossover Management, LLC
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+7.67%
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B
Braidwell LP
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+6.39%
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Frequently Asked Questions

What is Dyne Therapeutics, Inc (DYN) stock price today?

The current price of DYN is 18.13 USD — it has increased 6.09

What is Dyne Therapeutics, Inc (DYN)'s business?

Dyne Therapeutics, Inc. is a clinical-stage neuromuscular disease company. It is discovering and advancing therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE platform, it is developing targeted therapeutics that deliver to muscle and central nervous system (CNS). It has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 and Duchenne muscular dystrophy and preclinical programs for facioscapulohumeral muscular dystrophy and Pompe disease. Its product candidate, zeleciment basivarsen (also known as DYNE-101), is being evaluated in ACHIEVE, an ongoing Phase I/II global clinical trial in patients with DM1. Its product candidate, zeleciment rostudirsen (also known as DYNE-251), is being evaluated in DELIVER, an ongoing Phase I/II global clinical trial in patients with DMD who have mutations amenable to skipping exon 51. Its other product candidates are DYNE-302 and DYNE-401.

What is the price predicton of DYN Stock?

Wall Street analysts forecast DYN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DYN is39.33 USD with a low forecast of 17.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Dyne Therapeutics, Inc (DYN)'s revenue for the last quarter?

Dyne Therapeutics, Inc revenue for the last quarter amounts to -116.13M USD, increased 19.59

What is Dyne Therapeutics, Inc (DYN)'s earnings per share (EPS) for the last quarter?

Dyne Therapeutics, Inc. EPS for the last quarter amounts to -112316000.00 USD, increased 31.50

How many employees does Dyne Therapeutics, Inc (DYN). have?

Dyne Therapeutics, Inc (DYN) has 258 emplpoyees as of April 01 2026.

What is Dyne Therapeutics, Inc (DYN) market cap?

Today DYN has the market capitalization of 2.99B USD.