Relmada Therapeutics Shares Surge 40.8% on Promising Trial Data
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Mar 09 2026
0mins
Source: Benzinga
- Market Decline: U.S. stocks fell broadly on Monday, with the Dow Jones index dropping around 650 points, indicating investor concerns about economic outlook which may impact consumer spending and overall market confidence.
- Relmada Stock Surge: Shares of Relmada Therapeutics Inc. soared 40.8% to $6.27 during Monday's session, driven by the release of promising interim data from its Phase 2 trial of NDV-01 for treating non-muscle invasive bladder cancer.
- Clinical Trial Results: The 12-month interim data revealed a complete response rate of 76%, with an impressive 80% in the BCG-unresponsive patient population, providing strong support for Relmada's treatment approach and potentially enhancing market acceptance.
- Positive Market Reaction: The favorable feedback from clinical data has led to optimistic investor sentiment regarding Relmada's future prospects, not only boosting the company's stock price but also likely attracting more investor interest in its ongoing research and development efforts.
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Analyst Views on CRCL
Wall Street analysts forecast CRCL stock price to rise
17 Analyst Rating
10 Buy
4 Hold
3 Sell
Moderate Buy
Current: 64.070
Low
65.00
Averages
143.07
High
280.00
Current: 64.070
Low
65.00
Averages
143.07
High
280.00
About CRCL
Circle Internet Group, Inc. is a global financial technology company. It operates as a platform, network, and market infrastructure for stablecoin and blockchain applications and the issuer of a United States dollar-denominated stablecoin, USDC and a euro-denominated stablecoin, EURC (collectively Circle stablecoins). It provides a stablecoin network and a range of blockchain-specific software infrastructure. Its product offerings include Stablecoins, Developer Services, Integration Services, and Tokenized Funds. Developer Services develops an array of developer-ready and enterprise-grade infrastructure services that developers can plug into their own applications. It connects and integrates products, such as USDC across blockchain networks. Its Tokenized Funds are regulated yield-bearing investments for collateral use in capital markets. It also offers liquidity services, which provides institutional minting, reserving, redemption, and foreign exchange services for Circle stablecoins.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- SpaceX Investment Dynamics: Although SpaceX has only recently gone public, Wood has already included it among her top ten holdings and increased her stake as the stock price declined, indicating her confidence in the company's potential to disrupt traditional industries in satellite internet and chip manufacturing, though high valuations and technical challenges remain.
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- SpaceX Accumulation: Cathie Wood has made SpaceX one of her top ten holdings shortly after its IPO, continuing to buy on dips despite high valuations and technical hurdles, demonstrating her strong belief in its disruptive potential.
- Cerebras Investment Opportunity: Recently, Wood has increased her stake in Cerebras, known for its innovative SRAM-embedded chip technology; while currently a niche player, its partnership with OpenAI could drive significant disruption in the inference market.
- Tesla's Robotaxi Ambitions: Despite a drop in Tesla's stock due to weak U.S. deliveries, Wood remains optimistic about its robotaxi plans, believing in its long-term potential in the EV market, although it faces safety issues and competition challenges.
- Circle Internet's Market Position: Wood has been buying Circle Internet on the pullback, even as its stock has lost nearly 70% over the past year; however, its strong liquidity and integration in decentralized finance keep it competitive in the stablecoin market.
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- User Base Expansion: With nearly 28 million users, Robinhood now allows deposits of stablecoins into Lighter's smart contracts as collateral for trading, although the product is unavailable in the U.S. and other regions, it still provides Lighter with a new source of traffic.
- Tokenomics Optimization: Lighter has adjusted its tokenomics model, where trading fees will be used to repurchase and burn tokens, akin to stock buybacks, which will directly benefit holders by increasing the scarcity and value of its tokens.
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- Increased Market Competition: The partnership between Robinhood and Lighter enables the latter to tap into Robinhood's nearly 28 million users for decentralized perpetual contract trading, although the product is unavailable in the U.S. and other regions, it still opens new market opportunities for Lighter.
- Significant Volume Surge: Lighter achieved a 24-hour trading volume of $1.3 billion on July 7, despite its revenue plummeting to $20 million in Q1 2026 and less than $10 million in Q2 2026, the support from Robinhood is crucial for its future growth.
- Tokenomics Enhancement: Lighter has revamped its tokenomics model, where trading fees will be used for token buybacks and burns, aiming to reduce circulating supply and enhance value for holders, which is expected to attract more users to trade on its platform.
- Hyperliquid's Competitive Edge: Hyperliquid commands a 61.5% share of the decentralized perpetuals market, generating $202 million in trading fee revenue in Q2 alone, and with its partnerships with Coinbase and Circle, it is projected to secure $137 million to $160 million annually for buybacks, further solidifying its market position.
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- Stock Volatility: Circle Internet Group's shares plummeted 44.6% in June 2026, with a single-day drop of 17.6%, primarily driven by heightened market concerns over its core business, especially with the looming threat of the new competitor, Open USD stablecoin.
- Increased Competitive Pressure: The launch of Open USD stablecoin, backed by financial giants like Visa and BlackRock, is expected to directly capture market share from Circle, which currently holds approximately 26% of the market, second only to Tether.
- Index Removal Impact: Circle's stock was removed from five Russell indexes, leading to reduced demand from passive funds, which exacerbates the downward pressure on its stock amidst fragile cryptocurrency market sentiment.
- Uncertain Future Outlook: Although Circle continues to operate one of the most trusted stablecoins globally, its competitive moat is diminishing, prompting investors to watch how the company responds to the Open USD challenge, with potential strategies including partnerships or service expansion.
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- Stock Plunge: Circle Internet Group's stock plummeted 44.6% in June 2026, primarily driven by Bitcoin's decline and the emergence of new competitors, reflecting the high volatility of the crypto market and investor panic.
- Increased Competition: While Circle's USD Coin remains the second-largest stablecoin, it faces direct threats from the Open USD stablecoin, which is backed by financial giants like Visa and BlackRock, potentially eroding Circle's market share.
- Index Removal Impact: The removal of Circle's stock from five Russell indexes has led to a decrease in passive fund demand, exacerbating the downward pressure on the stock, especially amid the current fragile sentiment in the crypto market.
- Uncertain Future Outlook: Although Circle continues to operate one of the most trusted stablecoins globally, its competitive moat is shrinking, prompting investors to watch how the company responds to the Open USD challenge, which may require partnerships or business expansion to maintain its market position.
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