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DNTH Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
88.190
Open
85.410
VWAP
86.27
Vol
606.04K
Mkt Cap
4.24B
Low
85.000
Amount
52.28M
EV/EBITDA(TTM)
--
Total Shares
50.54M
EV
3.93B
EV/OCF(TTM)
--
P/S(TTM)
1.59K
Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company engaged in designing and delivering monoclonal antibodies with improved selectivity and potency. The Company is focused on developing complement therapeutics for patients living with severe autoimmune and inflammatory diseases. Its advanced product candidate, DNTH103, is a clinical-stage, highly potent, selective and fully human monoclonal immunoglobulin G4 with picomolar binding affinity that is designed to selectively bind only to the active form of C1s. DNTH103 is engineered with YTE half-life extension technology, a specific three amino acid change in the Fc domain, and has a pharmacokinetic (PK) profile designed to support less frequent, lower dose, self-administration as a convenient S.C. injection. It is conducting three mid- to late-stage clinical trials with DNTH103 in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN).
Show More

Events Timeline

(ET)
2026-03-11
06:10:00
Deal Size Increased to $625M in Common Stock
select
2026-03-09 (ET)
2026-03-09
16:20:00
Major Averages Volatile Amid Oil Price Spike
select
2026-03-09
16:10:00
Dianthus Therapeutics Launches $400M Public Offering
select

News

NASDAQ.COM
9.5
09:04 AMNASDAQ.COM
PinnedDianthus Therapeutics Shares Surge 5.6% on Positive Pipeline News
  • Stock Price Surge: Dianthus Therapeutics saw its shares rise 5.6% to close at $83.92, with trading volume significantly exceeding normal levels, indicating strong investor confidence in the company's prospects.
  • Clinical Trial Progress: The company achieved interim responder goals ahead of schedule in the CAPTIVATE study for its drug claseprubart targeting chronic inflammatory demyelinating polyneuropathy (CIDP), which fueled positive investor expectations and boosted the stock price.
  • FDA Approval Changes: The FDA agreed to several proposed changes in the clinical development of claseprubart, including updates to screening criteria and safety monitoring, which apply to all ongoing and future studies, further enhancing market confidence in the drug.
  • Declining Financial Outlook: Despite the stock price increase, the company is expected to report a quarterly loss of $1.17 per share, reflecting a year-over-year decline of 42.7%, indicating ongoing concerns about future profitability.
seekingalpha
8.5
03-26seekingalpha
Dianthus Therapeutics FDA Approves Clinical Changes for Claseprubart
  • FDA Approval of Clinical Changes: Dianthus Therapeutics announced that the FDA agreed to several proposed changes for its lead candidate, claseprubart, marking a significant advancement in the treatment of autoimmune diseases, particularly generalized myasthenia gravis and chronic inflammatory demyelinating polyneuropathy.
  • Impact on Clinical Studies: The FDA's feedback includes changes to screening criteria, routine lab work, and autoimmune safety risk, which will apply to all current and future studies, expected to enhance patient recruitment efficiency and optimize study outcomes.
  • Positive Safety Data: Dianthus reported no incidences of systemic lupus erythematosus or drug-induced lupus in any of the claseprubart programs to date, which will bolster confidence among investors and regulators regarding the drug's safety profile.
  • Positive Market Reaction: Following the FDA's announcement, Dianthus's shares spiked on Thursday, reflecting market optimism about the company's future clinical developments and further solidifying its position in the biotechnology sector.
Fool
8.5
03-18Fool
5AM Venture Management Fully Exits Dianthus Therapeutics
  • Full Exit: On February 17, 2026, 5AM Venture Management disclosed through an SEC filing that it sold its entire stake of 365,053 shares in Dianthus Therapeutics for $14.36 million, indicating a complete exit that may affect market confidence in the company.
  • Stock Performance: As of Wednesday, shares of Dianthus Therapeutics were priced at $80.68, reflecting a 288% increase over the past year; however, this exit occurred before much of the stock's recent surge, highlighting the need for investors to focus on the company's future execution.
  • Market Capitalization: Dianthus has a market capitalization of $3.5 billion, yet its trailing twelve-month revenue stands at only $3.08 million with a net loss of $126.34 million, indicating that the company remains in a clinical phase with uncertain future profitability.
  • R&D Strategy: Dianthus focuses on developing monoclonal antibody therapies for severe autoimmune and inflammatory diseases, with its lead program DNTH103 in clinical trials; despite high risks, its innovative R&D strategy could provide long-term growth potential for the company.
Yahoo Finance
8.5
03-15Yahoo Finance
Dianthus Therapeutics Hits Early 'Go' in CAPTIVATE Phase 3 CIDP Trial
  • Trial Design Changes: Dianthus announced that the interim analysis of the CAPTIVATE Phase 3 trial met its responder goal with 20 confirmed NCAT responders, raising the responder assumption to 50%, and eliminating the 600 mg arm, transitioning to a randomized withdrawal study comparing 300 mg to placebo, reducing the projected patient count from 192 to 128, optimizing resource allocation.
  • Reassuring Safety Signals: The interim analysis reported no safety events or indications of autoimmune activation, ensuring the safety profile of claseprubart in CIDP patients, which management expressed satisfaction with, believing it will enhance market confidence and drive further research.
  • Strong Financial Position: Dianthus management reiterated a cash balance of approximately $514 million as of December 31, 2023, expected to fund operations into 2028, demonstrating the company's financial capability to advance clinical trials and market expansion.
  • Significant Market Opportunity: CIDP is viewed as a multi-billion dollar market, with management planning to initiate a Phase 3 trial for generalized myasthenia gravis in mid-2026, expecting top-line results in the second half of 2028, reflecting the company's confidence in future growth.
moomoo
5.0
03-12moomoo
Dianthus Therapeutics (DNTH.US) Director Plans to Sell $10.55 Million in Common Stock via Form 144
  • Stock Sale Announcement: Director Marino Garcia intends to sell 122,920 shares of its common stock on March 12.
  • Market Value: The total market value of the shares being sold is approximately $10.55 million.
NASDAQ.COM
2.0
03-11NASDAQ.COM
Dianthus Therapeutics Prices $625 Million Upsized Public Offering
  • Upsized Financing: Dianthus Therapeutics is offering 7.31 million shares at $81 each, raising $625 million, expected to close on March 12, 2026, to support multiple programs targeting severe autoimmune and neuromuscular diseases.
  • Clinical Trial Advancements: The lead program, Claseprubart, is set to initiate a Phase 3 trial for generalized myasthenia gravis in mid-2026, with topline results anticipated in 2H 2028, highlighting the company's strategic focus on high unmet medical needs.
  • Early Clinical Success: Claseprubart achieved an early
Wall Street analysts forecast DNTH stock price to rise
6 Analyst Rating
Wall Street analysts forecast DNTH stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Wells Fargo
Sadia Rahman
Overweight
initiated
$135
AI Analysis
2026-03-19
Reason
Wells Fargo
Sadia Rahman
Price Target
$135
AI Analysis
2026-03-19
initiated
Overweight
Reason
Wells Fargo analyst Sadia Rahman initiated coverage of Dianthus with an Overweight rating and $135 price target. The firm says the company's claseprubart "stands out" in the complement inhibitor class. The drug has potential labeling and dosing advantages that support $5B-$6B in multi-indication peak sales potential, the analyst tells investors in a research note. Meanwhile, DNTH212 offers "upside optionality" for Dianthus, adds Wells.
Wedbush
Laura Chico
Outperform
maintain
$80 -> $103
2026-03-12
Reason
Wedbush
Laura Chico
Price Target
$80 -> $103
2026-03-12
maintain
Outperform
Reason
Wedbush analyst Laura Chico raised the firm's price target on Dianthus to $103 from $80 and keeps an Outperform rating on the shares. Following the completion of the recent Dianthus secondary offering, the firm is incorporating the $675M raise in its estimates and assumes exercise of the overallotment. While Wedbush awaits more detailed data from CAPTIVATE, the firm anticipates a more favorable response rate and convenient dosing vs. riliprubart, which should make claseprubart competitive in CIDP.
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Valuation Metrics

The current forward P/E ratio for Dianthus Therapeutics Inc (DNTH.O) is 0.00, compared to its 5-year average forward P/E of -7.79. For a more detailed relative valuation and DCF analysis to assess Dianthus Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.79
Current PE
0.00
Overvalued PE
-5.10
Undervalued PE
-10.48

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.68
Current EV/EBITDA
-28.44
Overvalued EV/EBITDA
3.75
Undervalued EV/EBITDA
-7.11

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
543.26
Current PS
2457.64
Overvalued PS
1099.72
Undervalued PS
-13.21

Financials

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Annual
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Whales Holding DNTH

F
Fairmount Funds Management LLC
Holding
DNTH
+19.18%
3M Return
V
VR Management, LLC
Holding
DNTH
+15.49%
3M Return
V
Vivo Capital, LLC
Holding
DNTH
+14.23%
3M Return
T
TCG Crossover Management, LLC
Holding
DNTH
+7.67%
3M Return
B
Braidwell LP
Holding
DNTH
+6.39%
3M Return
T
Tang Capital Management, LLC
Holding
DNTH
+1.48%
3M Return

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Frequently Asked Questions

What is Dianthus Therapeutics Inc (DNTH) stock price today?

The current price of DNTH is 85.61 USD — it has increased 2.01

What is Dianthus Therapeutics Inc (DNTH)'s business?

Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company engaged in designing and delivering monoclonal antibodies with improved selectivity and potency. The Company is focused on developing complement therapeutics for patients living with severe autoimmune and inflammatory diseases. Its advanced product candidate, DNTH103, is a clinical-stage, highly potent, selective and fully human monoclonal immunoglobulin G4 with picomolar binding affinity that is designed to selectively bind only to the active form of C1s. DNTH103 is engineered with YTE half-life extension technology, a specific three amino acid change in the Fc domain, and has a pharmacokinetic (PK) profile designed to support less frequent, lower dose, self-administration as a convenient S.C. injection. It is conducting three mid- to late-stage clinical trials with DNTH103 in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN).

What is the price predicton of DNTH Stock?

Wall Street analysts forecast DNTH stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DNTH is77.00 USD with a low forecast of 46.00 USD and a high forecast of 125.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Dianthus Therapeutics Inc (DNTH)'s revenue for the last quarter?

Dianthus Therapeutics Inc revenue for the last quarter amounts to 284.00K USD, decreased -78.58

What is Dianthus Therapeutics Inc (DNTH)'s earnings per share (EPS) for the last quarter?

Dianthus Therapeutics Inc. EPS for the last quarter amounts to -1.43 USD, increased 78.75

How many employees does Dianthus Therapeutics Inc (DNTH). have?

Dianthus Therapeutics Inc (DNTH) has 92 emplpoyees as of April 01 2026.

What is Dianthus Therapeutics Inc (DNTH) market cap?

Today DNTH has the market capitalization of 4.24B USD.