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DNTH Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
85.000
Open
83.640
VWAP
82.43
Vol
2.48M
Mkt Cap
4.51B
Low
79.790
Amount
204.26M
EV/EBITDA(TTM)
--
Total Shares
54.67M
EV
3.40B
EV/OCF(TTM)
--
P/S(TTM)
2.57K
Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for the treatment of severe autoimmune diseases. The Company's lead clinical-stage candidate, claseprubart, is a monoclonal antibody that is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein (C1s) - enabling less frequent and convenient self-administered subcutaneous (S.C.) injections suitable for a pre-filled pen. It is conducting three mid- to late-stage clinical trials with claseprubart in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN). The Company's second clinical-stage candidate, DNTH212, is an investigational, extended half-life bifunctional fusion protein targeting plasmacytoid dendritic cell BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function.
Show More

Events Timeline

(ET)
2026-06-12
15:30:00
Dianthus Therapeutics Reports 75% Response Rate for Claseprubart
select
2026-06-12
12:30:00
Dianthus Stock Rises 7.7% to $82.37
select
2026-06-10 (ET)
2026-06-10
16:30:00
US Stocks Drop Sharply Amid Renewed US-Iran Tensions
select
2026-06-10
12:10:00
Major U.S. Averages Decline Amid Escalating Geopolitical Tensions
select
2026-06-10
12:10:00
Dianthus Stock Price Drops 16.0%
select
2026-06-10
10:10:00
Dianthus Shares Down 13.7%
select

News

stocktwits
9.5
06-12stocktwits
Dianthus Therapeutics Receives Strong Buy Rating Following Positive Trial Results
  • Clinical Trial Success: Dianthus Therapeutics reported that 75% of patients in its trial for claseprubart, aimed at chronic inflammatory demyelinating polyneuropathy (CIDP), showed significant improvement, exceeding the company's expectation of 50%, thereby enhancing its competitive position in the market.
  • Positive Market Reaction: Following the announcement of favorable clinical data, Dianthus's stock surged 8% on Friday, marking its best performance since March, indicating strong investor confidence in its future potential.
  • Analyst Rating Maintained: Investment bank Raymond James reaffirmed its 'Strong Buy' rating on Dianthus, keeping the price target at $125 per share, reflecting a positive market outlook, especially in comparison to competing drugs from Sanofi.
  • Future Guidance: Dianthus expects to provide guidance on the timing of Part B top-line results by the end of 2026, further increasing investor interest in its research progress, particularly in the treatment of CIDP and other neurological disorders.
NASDAQ.COM
4.5
06-10NASDAQ.COM
US Stocks Plunge Amid Rising Geopolitical Tensions
  • Market Decline: On Wednesday, the S&P 500 Index fell by 1.62%, the Dow Jones Industrial Average dropped by 1.87%, and the Nasdaq 100 Index decreased by 1.98%, indicating a significant market reaction to rising geopolitical tensions that undermined investor confidence.
  • Oil Price Surge: Crude oil prices rose over 2% due to escalating tensions in the Middle East, which not only exacerbated losses in stocks and bonds but also pressured airline and trucking companies, highlighting the profound impact of energy price fluctuations on the overall market.
  • Stable Inflation Data: The US May Consumer Price Index rose 4.2% year-over-year, in line with expectations, while core CPI increased by 2.9%, alleviating some inflation concerns, although rising oil prices may reignite scrutiny over inflationary pressures.
  • Tech Stock Retreat: Chipmakers and AI infrastructure stocks experienced significant declines, with Nvidia and Tesla both dropping over 3%, reflecting a waning confidence in tech stocks that could influence future investment strategies.
NASDAQ.COM
4.5
06-10NASDAQ.COM
US Stocks Decline as Chip and Airline Stocks Weigh Down Market
  • Market Decline: The S&P 500 Index fell by 0.61%, the Dow Jones Industrial Average dropped by 0.88%, and the Nasdaq 100 Index decreased by 0.80%, indicating investor concerns over chipmakers and AI infrastructure stocks, which reflects a weakening confidence in technology stocks.
  • Inflation Data Impact: The US May Consumer Price Index rose by 4.2% year-on-year, meeting expectations and marking the fastest increase in three years, which, while easing inflation concerns, still affects market sentiment and leads to more cautious expectations regarding future interest rate policies.
  • Pressure on Airlines and Transport: Trucking companies are under pressure as Amazon expanded its LTL freight service, with Old Dominion Freight Line and FedEx Freight down over 4% and 3% respectively, indicating growing concerns about increased competition in the transportation sector.
  • Energy Stocks Rise: WTI crude oil prices increased by over 1%, boosting energy producers like Devon Energy by more than 5%, suggesting that despite overall market weakness, the energy sector's profit outlook remains optimistic amid geopolitical tensions.
NASDAQ.COM
4.5
06-10NASDAQ.COM
US Stocks Decline as Inflation Data Eases Market Concerns
  • Market Decline: The S&P 500 index fell by 0.28%, the Dow Jones Industrial Average dropped by 0.38%, and the Nasdaq 100 index decreased by 0.28%, indicating that weakness in technology stocks is dragging down the broader market as investors rotate out of the sector.
  • Inflation Data Impact: The US May Consumer Price Index rose by 4.2% year-over-year, matching expectations and marking the fastest increase in three years, while the core CPI rose by 2.9%, also in line with forecasts, easing inflation concerns and limiting downside pressure on Treasury yields.
  • Pressure on Trucking Sector: Amazon's expansion of its LTL freight service to all US destinations has led to significant declines in trucking companies, with ArcBest and Old Dominion Freight Line down over 7% and 6% respectively, reflecting market worries about the trucking industry's outlook.
  • Energy Stocks Strength: WTI crude oil prices increased by more than 1%, boosting energy producers like Devon Energy, which rose over 4%, indicating that the energy sector retains resilience amid geopolitical tensions.
Globenewswire
8.5
05-19Globenewswire
Oorja Bio Secures $30 Million Series A Financing for IPF Therapy
  • Funding Support: Oorja Bio announced a $30 million Series A financing from Westlake BioPartners, which will be utilized to advance the clinical development of its first-in-class therapy ORJ-001 for idiopathic pulmonary fibrosis (IPF), marking a significant step forward in the treatment of fibrotic diseases.
  • Clinical Trial Plans: ORJ-001 is set to begin Phase 2 clinical trials in 2026, aiming to treat IPF by restoring the function of alveolar epithelial type 2 (AEC2) cells, a novel approach that could fill existing treatment gaps and improve patient quality of life.
  • Team Background: The founding team of Oorja Bio comprises biotechnology leaders with extensive experience in drug development and new treatment paradigms, including Sujay Kango and Janethe Pena, who previously led the development of sotatercept at Acceleron Pharma, showcasing strong execution capabilities and industry influence.
  • Market Need: Idiopathic pulmonary fibrosis affects over 150,000 adults in the U.S., with current therapies only able to slow disease progression without halting the decline in lung function, thus the successful development of ORJ-001 could provide new hope to meet this significant unmet medical need.
Newsfilter
8.5
05-19Newsfilter
Oorja Bio Secures $30 Million Series A Financing for IPF Therapy
  • Funding Support: Oorja Bio announced a $30 million Series A financing from Westlake BioPartners, which will be utilized to advance the clinical development of its first-in-class drug ORJ-001 for idiopathic pulmonary fibrosis (IPF), thereby addressing a significant therapeutic gap in this area.
  • Clinical Trial Plans: ORJ-001 is set to begin Phase 2 clinical trials in 2026, aiming to restore the function of alveolar epithelial type 2 (AEC2) cells to promote alveolar repair and reduce inflammatory and fibrotic signaling associated with pulmonary fibrosis, offering new treatment options for patients.
  • Team Background: The founding team of Oorja Bio consists of biotechnology leaders with extensive experience in drug development and new treatment paradigms, having previously led the product strategy and clinical development of sotatercept at Acceleron Pharma, showcasing strong execution capabilities and industry influence.
  • Market Need: Idiopathic pulmonary fibrosis is a life-threatening disease affecting over 150,000 adults in the U.S., with current therapies only able to slow disease progression without halting the decline in lung function, making the successful development of ORJ-001 potentially transformative for patient outcomes.
Wall Street analysts forecast DNTH stock price to rise
6 Analyst Rating
Wall Street analysts forecast DNTH stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Raymond James
Strong Buy
maintain
$125
AI Analysis
2026-06-12
Reason
Raymond James
Price Target
$125
AI Analysis
2026-06-12
maintain
Strong Buy
Reason
Raymond James reiterated a Strong Buy rating and $125 price target on Dianthus (DNTH) after the company reported data from Part A of its Phase 3 CAPTIVATE study evaluating claseprubart in chronic inflammatory demyelinating polyneuropathy. The study showed a 75% responder rate in the first roughly 50 patients, which is notably higher than the overall rate in Sanofi's (SNY) riliprubart Phase 2 study at week 24, the analyst tells investors in a research note. The firm said the responder rate beat its expectations, and that the response was shown broadly across multiple metrics. The firm added that study design could be the "big winner" here, as it is convinced a randomized withdrawal study design with a time-to-relapse endpoint is inherently less risky than the design in MOBILIZE, where riliprubart failed.
Evercore ISI
Gavin Clark-Gartner
Outperform
to
Outperform
downgrade
$122 -> $120
2026-05-11
Reason
Evercore ISI
Gavin Clark-Gartner
Price Target
$122 -> $120
2026-05-11
downgrade
Outperform
to
Outperform
Reason
Evercore ISI analyst Gavin Clark-Gartner lowered the firm's price target on Dianthus to $120 from $122 and keeps an Outperform rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DNTH
Unlock Now

Valuation Metrics

The current forward P/E ratio for Dianthus Therapeutics Inc (DNTH.O) is 0.00, compared to its 5-year average forward P/E of -7.79. For a more detailed relative valuation and DCF analysis to assess Dianthus Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.79
Current PE
0.00
Overvalued PE
-5.10
Undervalued PE
-10.48

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.09
Current EV/EBITDA
-24.43
Overvalued EV/EBITDA
4.22
Undervalued EV/EBITDA
-10.41

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
729.99
Current PS
2844.47
Overvalued PS
1554.79
Undervalued PS
-94.80

Financials

AI Analysis
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Whales Holding DNTH

F
Fairmount Funds Management LLC
Holding
DNTH
+20.18%
3M Return
N
Nantahala Capital Management, LLC
Holding
DNTH
+17.19%
3M Return
L
Logos Global Management, L.P.
Holding
DNTH
+12.15%
3M Return
B
Baker Bros. Advisors LP
Holding
DNTH
+10.49%
3M Return
V
VR Management, LLC
Holding
DNTH
+10.22%
3M Return
T
Tang Capital Management, LLC
Holding
DNTH
+7.54%
3M Return

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Frequently Asked Questions

What is Dianthus Therapeutics Inc (DNTH) stock price today?

The current price of DNTH is 82.49 USD — it has increased 0.73

What is Dianthus Therapeutics Inc (DNTH)'s business?

Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for the treatment of severe autoimmune diseases. The Company's lead clinical-stage candidate, claseprubart, is a monoclonal antibody that is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein (C1s) - enabling less frequent and convenient self-administered subcutaneous (S.C.) injections suitable for a pre-filled pen. It is conducting three mid- to late-stage clinical trials with claseprubart in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN). The Company's second clinical-stage candidate, DNTH212, is an investigational, extended half-life bifunctional fusion protein targeting plasmacytoid dendritic cell BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function.

What is the price predicton of DNTH Stock?

Wall Street analysts forecast DNTH stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DNTH is77.00 USD with a low forecast of 46.00 USD and a high forecast of 125.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Dianthus Therapeutics Inc (DNTH)'s revenue for the last quarter?

Dianthus Therapeutics Inc revenue for the last quarter amounts to 463.00K USD, decreased -60.19

What is Dianthus Therapeutics Inc (DNTH)'s earnings per share (EPS) for the last quarter?

Dianthus Therapeutics Inc. EPS for the last quarter amounts to -0.85 USD, increased 3.66

How many employees does Dianthus Therapeutics Inc (DNTH). have?

Dianthus Therapeutics Inc (DNTH) has 92 emplpoyees as of June 21 2026.

What is Dianthus Therapeutics Inc (DNTH) market cap?

Today DNTH has the market capitalization of 4.51B USD.