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DNTH Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
89.573
Open
86.620
VWAP
87.39
Vol
254.98K
Mkt Cap
4.76B
Low
85.470
Amount
22.28M
EV/EBITDA(TTM)
--
Total Shares
54.67M
EV
3.63B
EV/OCF(TTM)
--
P/S(TTM)
2.71K
Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company engaged in designing and delivering monoclonal antibodies with improved selectivity and potency. The Company is focused on developing complement therapeutics for patients living with severe autoimmune and inflammatory diseases. Its advanced product candidate, DNTH103, is a clinical-stage, highly potent, selective and fully human monoclonal immunoglobulin G4 with picomolar binding affinity that is designed to selectively bind only to the active form of C1s. DNTH103 is engineered with YTE half-life extension technology, a specific three amino acid change in the Fc domain, and has a pharmacokinetic (PK) profile designed to support less frequent, lower dose, self-administration as a convenient S.C. injection. It is conducting three mid- to late-stage clinical trials with DNTH103 in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN).
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Events Timeline

(ET)
2026-05-05
16:20:00
Dianthus Reports Q1 Revenue of $463,000, Exceeding Expectations
select
2026-05-01 (ET)
2026-05-01
10:00:00
Dianthus Therapeutics Granted FDA Orphan Designation for Claseprubart
select
link
2026-03-11 (ET)
2026-03-11
06:10:00
Deal Size Increased to $625M in Common Stock
select

News

Globenewswire
8.5
05-06Globenewswire
Leads Biolabs Partners with Dianthus to Advance LBL-047 Clinical Development
  • Clinical Development Strategy: Leads Biolabs' partner, Dianthus Therapeutics, has prioritized Sjögren's disease, systemic lupus erythematosus, and dermatomyositis for the clinical development of LBL-047, highlighting a commitment to addressing high unmet medical needs and potentially enhancing the company's market position in autoimmune diseases.
  • Funding Support: In March 2026, Dianthus completed an upsized public offering, raising approximately $719 million, which provides a robust capital foundation for the global development of LBL-047, thereby strengthening its growth potential in the competitive biopharmaceutical market.
  • Clinical Trial Progress: The Phase 1 study of LBL-047 was initiated in December 2025, with top-line results from healthy volunteers expected in the second half of 2026; successful completion of this phase will provide critical data to support further clinical development in prioritized indications.
  • Global Partnership Agreement: The exclusive global partnership agreement between Leads Biolabs and Dianthus, with a potential deal value of up to $1 billion, indicates the company's intent to expand in the global market, aiming to maximize the clinical and commercial potential of LBL-047 through collaborative development.
Newsfilter
8.5
05-06Newsfilter
Leads Biolabs Partners with Dianthus to Advance LBL-047 Clinical Development
  • Clinical Development Strategy: Leads Biolabs' partner, Dianthus Therapeutics, has prioritized Sjögren's disease, systemic lupus erythematosus, and dermatomyositis for the clinical development of LBL-047, highlighting a commitment to addressing high unmet medical needs, which may enhance the company's market share in autoimmune diseases.
  • Funding Support: Dianthus completed an upsized public offering in March 2026, raising approximately $719 million, providing a robust financial foundation for the global development of LBL-047, which is expected to accelerate clinical trial processes and boost investor confidence.
  • Clinical Trial Progress: The Phase 1 study of LBL-047 was initiated in December 2025, with top-line results from healthy volunteers anticipated in the second half of 2026, which will provide critical data for subsequent clinical development and further validate its application potential in autoimmune diseases.
  • Global Partnership Agreement: The exclusive global partnership agreement between Leads Biolabs and Dianthus, with a potential deal value of up to $1 billion, indicates the company's strategic positioning in the global market, aiming to maximize the clinical and commercial potential of LBL-047 through collaboration.
seekingalpha
9.5
05-05seekingalpha
Dianthus Therapeutics Q1 Earnings Beat Expectations
  • Earnings Highlights: Dianthus Therapeutics reported a Q1 GAAP EPS of -$0.85, beating expectations by $0.23, indicating some improvement in financial management, although overall revenue fell 60.3% year-over-year to $0.46M, reflecting ongoing market challenges.
  • Strong Cash Position: As of March 31, 2026, Dianthus holds approximately $1.2 billion in cash, cash equivalents, and investments, projected to sustain operations into 2030, enhancing its flexibility in R&D and market expansion.
  • Positive Market Reaction: Following the FDA's agreement to proposed changes in its lead program, Dianthus's stock price rose, indicating increased market confidence in the company's future prospects, which may attract more investor interest.
  • Successful Upsized Offering: Dianthus successfully priced a $625 million public offering at $81 per share, demonstrating investor recognition of its long-term strategy and providing robust funding support for future R&D and market initiatives.
Newsfilter
5.0
05-01Newsfilter
Dianthus Grants Equity Awards to New Employees
  • Equity Award Program: On May 1, 2026, Dianthus Therapeutics granted a total of 135,000 non-qualified stock options to six newly hired non-executive employees, with an exercise price of $87.42 per share, aimed at attracting top talent and strengthening the team.
  • Grant Conditions: The stock options were approved by the company's independent Compensation Committee and comply with Nasdaq Listing Rule 5635(c)(4), highlighting the company's strategic focus on attracting and retaining talent.
  • Vesting Arrangement: The options vest 25% on the first anniversary of the grant date, with the remaining 75% vesting in equal monthly installments over the following 36 months, which incentivizes long-term employee retention and alignment with company growth.
  • Company Background: Dianthus Therapeutics is dedicated to developing next-generation therapies for severe autoimmune diseases, backed by an experienced team of biotech and pharmaceutical executives committed to delivering transformative medicines, enhancing the company's competitive position in the biotech sector.
Fool
5.0
04-19Fool
Dianthus Therapeutics CFO Sells Shares for Profit
  • Executive Stock Sale: On April 9, 2026, Dianthus Therapeutics CFO Ryan Savitz sold 8,224 shares of common stock for approximately $739,000, reflecting a liquidity management strategy amid rising stock prices.
  • Option Exercise and Sale: The transaction was executed under a Rule 10b5-1 plan, resulting in Savitz's direct ownership dropping to zero, while he retains 71,776 unexercised options, indicating ongoing confidence in the company's future.
  • Positive Market Reaction: Following the announcement of favorable interim results for its lead drug candidate claseprubart, Dianthus's stock surged in March, leading to a proposed $400 million secondary offering that ultimately raised $719 million, showcasing strong market confidence in its R&D prospects.
  • Company Overview and Strategy: Dianthus focuses on developing monoclonal antibodies for severe autoimmune and inflammatory diseases, with its clinical-stage DNTH103 targeting various rare conditions, aiming to leverage innovative biologic therapies to meet unmet medical needs and strengthen its competitive position in the specialty therapeutics market.
NASDAQ.COM
5.0
04-19NASDAQ.COM
Dianthus Therapeutics CFO Sells Shares in Major Transaction
  • Executive Stock Sale: On April 9, 2026, Dianthus Therapeutics CFO Ryan Savitz sold 8,224 shares of common stock for approximately $739,000, marking a complete divestment of his direct holdings and indicating a potential lack of confidence in the stock.
  • Option Exercise and Sale: The transaction was structured as an option exercise and immediate sale, involving only direct holdings without participation from trusts or other entities, which signifies a total loss of direct control over his shares.
  • Future Potential Retained: Despite selling all direct shares, Savitz retains 71,776 stock options that can be converted into common stock in the future, suggesting he may still have confidence in the company's long-term prospects.
  • Market Response and Financing: Prior to Savitz's stock sale, Dianthus attracted significant institutional investment due to positive clinical trial results, culminating in a successful $719 million secondary offering, reflecting strong market confidence in its R&D pipeline.
Wall Street analysts forecast DNTH stock price to rise
6 Analyst Rating
Wall Street analysts forecast DNTH stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Current: 0.000
sliders
Low
46.00
Averages
77.00
High
125.00
Evercore ISI
Gavin Clark-Gartner
Outperform
to
Outperform
downgrade
$122 -> $120
AI Analysis
2026-05-11
New
Reason
Evercore ISI
Gavin Clark-Gartner
Price Target
$122 -> $120
AI Analysis
2026-05-11
New
downgrade
Outperform
to
Outperform
Reason
Evercore ISI analyst Gavin Clark-Gartner lowered the firm's price target on Dianthus to $120 from $122 and keeps an Outperform rating on the shares.
Raymond James
Strong Buy
maintain
$123 -> $125
2026-05-06
Reason
Raymond James
Price Target
$123 -> $125
2026-05-06
maintain
Strong Buy
Reason
Raymond James raised the firm's price target on Dianthus to $125 from $123 and keeps a Strong Buy rating on the shares. Dianthus' Q1 update highlighted pipeline progress including prioritized indications for DNTH212 supported by its dual BDCA2 and BAFF/APRIL mechanism, orphan drug designation for claseprubart in gMG, and multiple near-term catalysts including Phase 1 data in 2H26, a Phase 2 readout in MMN in Q4, and planned Phase 3 initiation in mid-2026 with topline results expected in 2H28, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DNTH
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Valuation Metrics

The current forward P/E ratio for Dianthus Therapeutics Inc (DNTH.O) is 0.00, compared to its 5-year average forward P/E of -7.79. For a more detailed relative valuation and DCF analysis to assess Dianthus Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.79
Current PE
0.00
Overvalued PE
-5.10
Undervalued PE
-10.48

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.09
Current EV/EBITDA
-22.35
Overvalued EV/EBITDA
3.64
Undervalued EV/EBITDA
-7.82

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
630.82
Current PS
2588.54
Overvalued PS
1326.77
Undervalued PS
-65.14

Financials

AI Analysis
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Quarterly

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Whales Holding DNTH

F
Fairmount Funds Management LLC
Holding
DNTH
+27.99%
3M Return
V
VR Management, LLC
Holding
DNTH
+18.25%
3M Return
B
Braidwell LP
Holding
DNTH
+16.06%
3M Return
T
TCG Crossover Management, LLC
Holding
DNTH
+11.42%
3M Return
N
Nantahala Capital Management, LLC
Holding
DNTH
+10.33%
3M Return
B
Baker Bros. Advisors LP
Holding
DNTH
+6.13%
3M Return

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Frequently Asked Questions

What is Dianthus Therapeutics Inc (DNTH) stock price today?

The current price of DNTH is 87.12 USD — it has increased 0.47

What is Dianthus Therapeutics Inc (DNTH)'s business?

Dianthus Therapeutics, Inc. is a clinical-stage biotechnology company engaged in designing and delivering monoclonal antibodies with improved selectivity and potency. The Company is focused on developing complement therapeutics for patients living with severe autoimmune and inflammatory diseases. Its advanced product candidate, DNTH103, is a clinical-stage, highly potent, selective and fully human monoclonal immunoglobulin G4 with picomolar binding affinity that is designed to selectively bind only to the active form of C1s. DNTH103 is engineered with YTE half-life extension technology, a specific three amino acid change in the Fc domain, and has a pharmacokinetic (PK) profile designed to support less frequent, lower dose, self-administration as a convenient S.C. injection. It is conducting three mid- to late-stage clinical trials with DNTH103 in generalized Myasthenia Gravis (gMG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN).

What is the price predicton of DNTH Stock?

Wall Street analysts forecast DNTH stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DNTH is77.00 USD with a low forecast of 46.00 USD and a high forecast of 125.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Dianthus Therapeutics Inc (DNTH)'s revenue for the last quarter?

Dianthus Therapeutics Inc revenue for the last quarter amounts to 463.00K USD, decreased -60.19

What is Dianthus Therapeutics Inc (DNTH)'s earnings per share (EPS) for the last quarter?

Dianthus Therapeutics Inc. EPS for the last quarter amounts to -0.85 USD, increased 3.66

How many employees does Dianthus Therapeutics Inc (DNTH). have?

Dianthus Therapeutics Inc (DNTH) has 92 emplpoyees as of May 12 2026.

What is Dianthus Therapeutics Inc (DNTH) market cap?

Today DNTH has the market capitalization of 4.76B USD.