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XENE Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
54.185
Open
54.040
VWAP
53.37
Vol
1.14M
Mkt Cap
5.09B
Low
52.545
Amount
60.96M
EV/EBITDA(TTM)
--
Total Shares
95.43M
EV
4.47B
EV/OCF(TTM)
--
P/S(TTM)
575.07
Xenon Pharmaceuticals Inc. is a Canada-based neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing therapeutics to improve the lives of people living with neurological and psychiatric disorders. The Company is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. Azetukalner, a novel, highly potent, selective Kv7 potassium channel opener, represents the advanced, clinically validated potassium channel modulator in late-stage clinical development for the treatment of multiple indications that include epilepsy, including focal onset seizures (FOS), and primary generalized tonic-clonic seizures (PGTCS), as well as neuropsychiatric disorders including major depressive disorder (MDD), and bipolar depression (BPD). The Company is evaluating multiple therapeutic candidates targeting Kv7, Nav1.7, and Nav1.1 across various indications.
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Events Timeline

(ET)
2026-03-11
06:00:00
Deal Size Increased to $650M in Common Stock
select
2026-03-09 (ET)
2026-03-09
16:20:00
Major Averages Volatile Amid Oil Price Spike
select

News

Fool
6.5
03-13Fool
Driehaus Capital Increases Stake in Xenon Pharmaceuticals
  • Increased Holdings: Driehaus Capital Management disclosed a purchase of 369,577 shares of Xenon Pharmaceuticals in Q4 2025, valued at approximately $15.52 million, indicating strong confidence in the company.
  • Market Value Growth: This acquisition raised Driehaus's stake in Xenon to 1.4%, with the total position value increasing to $36.03 million at quarter-end, reflecting positive market expectations for the company.
  • Clinical Advancements: Xenon's lead drug candidate, Azetukalner, demonstrated significant efficacy in Phase 3 trials for focal onset seizures, with a median seizure frequency reduction of 53.2% in high-dose patients, paving the way for future commercialization.
  • Funding Support: The company recently completed a $747.5 million public offering, significantly strengthening its financial position to support commercialization and pipeline expansion, with market response being positive as shares surged over 30% following the trial results.
NASDAQ.COM
8.5
03-11NASDAQ.COM
Xenon Pharmaceuticals Prices $650 Million Upsized Public Offering
  • Offering Size: Xenon Pharmaceuticals announced the pricing of its upsized public offering of 10.53 million shares at $57 each, expecting gross proceeds of $650 million, reflecting strong market demand and investor confidence.
  • Pre-Funded Warrants: The company issued pre-funded warrants for 0.87 million shares at $56.99 each to certain investors, enhancing financing flexibility and attracting additional investor participation.
  • Clinical Trial Progress: Xenon's lead investigational molecule, Azetukalner, achieved positive results in Phase 3 trials for focal onset seizures, with a median percent change in monthly seizure frequency of 53.2% in the 25 mg dose group, indicating significant efficacy.
  • Future Outlook: The company plans to submit a New Drug Application for Azetukalner to the U.S. FDA in Q3 2026, and if approved, it will be the only KV7 potassium channel opener available for epilepsy treatment, further solidifying its market position in neuroscience.
seekingalpha
8.5
03-11seekingalpha
Xenon Pharmaceuticals Upsizes Public Offering to $650 Million
  • Upsized Offering: Xenon Pharmaceuticals has announced an increase in its public offering from an initial target of $500 million to $650 million, issuing 10.53 million common shares and pre-funded warrants, indicating strong market demand for its stock.
  • Pricing Strategy: The common shares are priced at $57.00 each, while the pre-funded warrants are priced at $56.9999 each, with expected gross proceeds of approximately $650 million, excluding expenses, which will significantly bolster the company's financial position.
  • Underwriter Option: The underwriters have a 30-day option to purchase an additional 1.71 million common shares at the public offering price, providing the company with additional fundraising flexibility that may further enhance market confidence.
  • Expected Closing Date: The offering is anticipated to close around March 12, 2026, pending standard closing conditions, providing investors with a clear timeline for expected capital inflow.
Benzinga
6.0
03-10Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Changes: Top Wall Street analysts have adjusted their ratings on several companies, indicating a shift in market sentiment that could influence investor decisions and market trends.
  • Upgrades and Downgrades: While specific upgrades and downgrades are not detailed, such changes typically have a significant impact on the short-term performance of the affected stocks, prompting investors to pay close attention to these adjustments.
  • Market Reaction Expectations: The adjustments in analyst ratings may lead to increased attention on AZO stock, as investors reassess their strategies based on these changes, potentially affecting trading volumes and price fluctuations.
  • Source Reliability: The market news and data provided by Benzinga serve as a crucial reference for investors; although it does not offer investment advice, its analyst ratings page provides a comprehensive view of rating changes for informed decision-making.
NASDAQ.COM
6.0
03-10NASDAQ.COM
Xenon Pharmaceuticals Stock Surpasses Analyst Target Price
  • Price Target Breakthrough: Xenon Pharmaceuticals' stock has reached $62.67, surpassing the analyst's 12-month target price of $56.39, indicating market optimism about the company's prospects, which may prompt analysts to reassess their target prices.
  • Analyst Target Distribution: Among the 19 analysts covered by Zacks, target prices range from $47.00 to $66.00, with a standard deviation of $5.468, reflecting significant variance in market expectations and differing views on the company's future performance.
  • Investor Signal: The stock's breach of the target price provides investors with an opportunity to reassess Xenon Pharmaceuticals, prompting them to consider whether the current valuation is justified or if they should take profits to mitigate risk.
  • Market Reaction Analysis: Analysts' reactions could influence stock price movements; if the majority opt to raise their target prices, it may further drive the stock price up, while downgrades could lead to a price pullback.
stocktwits
8.5
03-10stocktwits
Xenon Plans New Drug Application Submission
  • Trial Results Exceed Expectations: Xenon announced that its azetukalner showed a median percent change of 53.2% in monthly focal onset seizure frequency at the 25 mg dose, significantly outperforming the placebo's 10.4%, which not only validates the drug's efficacy but also lays a solid foundation for future FDA submissions.
  • New Drug Application Plans: The company plans to submit a new drug application for azetukalner to the U.S. FDA in Q3 2026, with CEO Ian Mortimer stating that the trial results “exceeded expectations,” potentially reshaping the epilepsy treatment landscape to meet the needs of 50% of patients seeking better control.
  • Positive Market Reaction: Following the trial data announcement, Xenon's stock surged 50%, with Jefferies and RBC Capital raising their price targets to $100 and $80 respectively, reflecting strong market confidence in azetukalner and its significant sales potential in the future.
  • Competitor Dynamics: Despite Biohaven's opakalim having safety disadvantages, Raymond James maintains a ‘Strong Buy’ rating, anticipating pivotal trial results in H2 2026 that will further clarify its market positioning.
Wall Street analysts forecast XENE stock price to rise
14 Analyst Rating
Wall Street analysts forecast XENE stock price to rise
14 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
44.00
Averages
54.09
High
62.00
Current: 0.000
sliders
Low
44.00
Averages
54.09
High
62.00
Wedbush
Outperform -> NULL
downgrade
$64 -> $63
AI Analysis
2026-03-16
Reason
Wedbush
Price Target
$64 -> $63
AI Analysis
2026-03-16
downgrade
Outperform -> NULL
Reason
Wedbush lowered the firm's price target on Xenon Pharmaceuticals to $63 from $64 and keeps an Outperform rating on the shares. Following completion of the upsized $748M secondary offering, the firm is incorporating the raise into its estimates.
Wedbush
Outperform
maintain
$47 -> $64
2026-03-10
Reason
Wedbush
Price Target
$47 -> $64
2026-03-10
maintain
Outperform
Reason
Wedbush raised the firm's price target on Xenon Pharmaceuticals to $64 from $47 and keeps an Outperform rating on the shares. The much-anticipated XTOLE2 Phase 3 data for azetukalner arrived with the trial meeting its primary endpoint for both doses, the firm notes. While Wedbush awaits more detailed data presentation at the AAN late-breaker, the median percent change in monthly seizure frequency appears compelling on a placebo-adjusted basis. Important to note, that over half of study participants received at least 3 anti-epileptic drugs indicating this is a challenging population to address.
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Valuation Metrics

The current forward P/E ratio for Xenon Pharmaceuticals Inc (XENE.O) is -9.42, compared to its 5-year average forward P/E of -12.13. For a more detailed relative valuation and DCF analysis to assess Xenon Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-12.13
Current PE
-9.42
Overvalued PE
-9.56
Undervalued PE
-14.70

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-7.29
Current EV/EBITDA
-7.52
Overvalued EV/EBITDA
-3.43
Undervalued EV/EBITDA
-11.15

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2203.13
Current PS
0.00
Overvalued PS
5895.38
Undervalued PS
-1489.12

Financials

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Whales Holding XENE

C
Commodore Capital LP
Holding
XENE
+5.81%
3M Return
D
Driehaus Capital Management LLC
Holding
XENE
+5.77%
3M Return
A
Artal Group S.A.
Holding
XENE
+1.27%
3M Return
V
Vestal Point Capital, LP
Holding
XENE
+0.55%
3M Return
S
Sofinnova Investment, Inc.
Holding
XENE
-1.57%
3M Return
B
Braidwell LP
Holding
XENE
-2.26%
3M Return

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Frequently Asked Questions

What is Xenon Pharmaceuticals Inc (XENE) stock price today?

The current price of XENE is 53.38 USD — it has decreased -1.91

What is Xenon Pharmaceuticals Inc (XENE)'s business?

Xenon Pharmaceuticals Inc. is a Canada-based neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing therapeutics to improve the lives of people living with neurological and psychiatric disorders. The Company is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. Azetukalner, a novel, highly potent, selective Kv7 potassium channel opener, represents the advanced, clinically validated potassium channel modulator in late-stage clinical development for the treatment of multiple indications that include epilepsy, including focal onset seizures (FOS), and primary generalized tonic-clonic seizures (PGTCS), as well as neuropsychiatric disorders including major depressive disorder (MDD), and bipolar depression (BPD). The Company is evaluating multiple therapeutic candidates targeting Kv7, Nav1.7, and Nav1.1 across various indications.

What is the price predicton of XENE Stock?

Wall Street analysts forecast XENE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XENE is54.09 USD with a low forecast of 44.00 USD and a high forecast of 62.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Xenon Pharmaceuticals Inc (XENE)'s revenue for the last quarter?

Xenon Pharmaceuticals Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Xenon Pharmaceuticals Inc (XENE)'s earnings per share (EPS) for the last quarter?

Xenon Pharmaceuticals Inc. EPS for the last quarter amounts to -1.31 USD, increased 55.95

How many employees does Xenon Pharmaceuticals Inc (XENE). have?

Xenon Pharmaceuticals Inc (XENE) has 358 emplpoyees as of March 25 2026.

What is Xenon Pharmaceuticals Inc (XENE) market cap?

Today XENE has the market capitalization of 5.09B USD.