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SRPT Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
17.990
Open
17.420
VWAP
17.76
Vol
3.65M
Mkt Cap
1.89B
Low
17.420
Amount
64.91M
EV/EBITDA(TTM)
9.25
Total Shares
105.58M
EV
2.07B
EV/OCF(TTM)
11.82
P/S(TTM)
0.89
Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS.
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Events Timeline

(ET)
2026-05-12
16:20:00
Major Averages Finish Mixed as Semiconductor Stocks Pull Back
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2026-05-12
14:00:00
FDA Commissioner Makary Resigns Over E-Cigarette Concerns
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link
2026-05-12
10:50:00
Trump Plans to Reduce Beef Import Tariffs
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2026-05-11 (ET)
2026-05-11
12:30:00
Trump Approves Firing of FDA Commissioner Makary
select
link
2026-05-11
10:20:00
Trump Plans to Fire FDA Commissioner, Biotech Stocks Affected
select
2026-05-08 (ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
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2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
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link
2026-05-06 (ET)
2026-05-06
17:20:00
Sarepta Therapeutics Q1 Revenue Reaches $730.8M
select

News

Fool
5.0
05-20Fool
Biotech Investment Environment Improves
  • Improved Market Conditions: Biotech investors are experiencing a friendlier macro environment not seen in years, with stabilizing interest rates, increased FDA activity, and pharmaceutical companies holding billions in cash while facing patent cliffs, creating a favorable backdrop for smaller biotech firms.
  • Schrödinger's Growth Potential: Schrödinger (SDGR) is guiding for a 10% to 15% growth in annual contract value (ACV) for 2026, reaching between $218 million and $228 million, showcasing strong growth potential in drug discovery, while reporting total revenue of $256 million for 2025, making it one of the few profitable AI-driven biotech companies.
  • Sarepta's Commercial Challenges: Sarepta (SRPT) reported net product revenue of $1.86 billion for 2025, and despite ongoing safety controversies surrounding its Elevidys gene therapy, it maintains a 2026 revenue guidance of $1.2 billion to $1.4 billion, demonstrating a robust commercial foundation in the Duchenne muscular dystrophy market.
  • NRX's Regulatory Progress: NRX Pharmaceuticals (NRXP) has received positive feedback from the FDA regarding its lead drug candidate, with a potential decision expected this summer, and while it faces financing and execution risks, its focus on severe depression treatments is attracting increasing investor interest.
NASDAQ.COM
2.0
05-20NASDAQ.COM
Analysis of Biotech Companies' Prospects
  • AI-Driven Drug Discovery: Schrödinger reported total revenue of $256 million in 2025, with $200 million from software, and management anticipates a 10% to 15% growth in annual contract value for 2026, highlighting its strong potential in drug development and market demand.
  • Sarepta's Gene Therapy Challenges: Sarepta achieved net product revenue of $1.86 billion in 2025, and despite safety concerns surrounding Elevidys, the company maintains its revenue guidance of $1.2 billion to $1.4 billion for 2026, indicating its ongoing competitiveness in the gene therapy market.
  • NRX's Regulatory Progress: NRX Pharmaceuticals is developing treatments for severe depression, and recent FDA feedback indicated no major issues with its preservative-free ketamine, with a potential decision expected this summer, which could significantly increase market attention if approved.
  • Improving Macro Environment: Biotech investors are experiencing a more favorable macro environment with stabilizing interest rates and increased FDA activity, providing a fertile backdrop for smaller biotech companies with strong pipelines and differentiated technologies to thrive.
Newsfilter
1.0
05-13Newsfilter
Sarepta to Participate in RBC Healthcare Conference
  • Management Participation: Sarepta Therapeutics' senior management will participate in the RBC Capital Markets Global Healthcare Conference on May 20, showcasing the company's leadership in precision genetic medicine, which is expected to attract investor interest.
  • Live Webcast Details: The conference will be broadcast live at 8:30 a.m. ET, with investors able to view it on Sarepta's website, and the presentation will be archived for 90 days post-event, ensuring access to critical information.
  • Mission Statement: Sarepta is committed to developing precision genetic medicine for rare diseases, particularly leading in Duchenne muscular dystrophy, demonstrating its robust portfolio across muscle, central nervous system, and cardiac diseases.
  • Information Posting Channels: The company regularly posts important information in the 'For Investors' section of its website, encouraging investors to visit frequently for updates, thereby enhancing transparency and investor confidence.
Newsfilter
5.0
05-13Newsfilter
FDA Commissioner's Departure Triggers Biotech Market Reactions
  • Leadership Change: The departure of FDA Commissioner Marty Makary is perceived as a positive signal for the biotech sector, although analysts warn that the industry may face pressure until a permanent replacement is found, potentially leading to market volatility.
  • Market Reaction: The Nasdaq biotechnology index rose 1% on Tuesday, reflecting an initial positive response from investors to Makary's exit, particularly following his public disagreements with drugmakers like Replimune and Moderna.
  • Increased Uncertainty: Analysts caution that the ongoing leadership vacuum at the FDA could result in more delays and unpredictability, diminishing the agency's ability to provide guidance and credible policy commitments, thereby impacting the investability of the biopharma ecosystem.
  • Stock Performance: Shares of uniQure and Replimune rose by 5% and nearly 10%, respectively, indicating market optimism regarding new leadership, although Makary's departure also introduces uncertainty within the industry.
stocktwits
6.5
05-08stocktwits
FDA Leadership Shakeup May Impact Biotech Stocks
  • Stock Price Surge: Following reports of potential dismissal of FDA Commissioner Marty Makary, shares of Replimune (REPL) and uniQure (QURE) surged by 17% and 15% respectively, indicating market optimism regarding regulatory improvements under new leadership.
  • Industry Response: The pharmaceutical industry has expressed dissatisfaction with Makary's drug review policies, citing inconsistencies and overly restrictive processes that hinder innovative drug approvals, suggesting that new leadership could accelerate approval timelines and restore clearer regulatory guidance.
  • Potential Beneficiaries: Companies like Replimune and uniQure, which have publicly clashed with the FDA, are seen as potential beneficiaries of new leadership, with Replimune's melanoma therapy RP1 being rejected and uniQure's Huntington's disease gene therapy AMT-130 facing significant shifts in review policy.
  • Market Reaction: Despite REPL's stock falling approximately 50% over the past year, QURE's stock has risen by 124%, reflecting investor confidence in the future of the biotech sector and expectations for changes in FDA policies.
seekingalpha
9.5
05-07seekingalpha
Sarepta Therapeutics Q1 2026 Earnings Call Insights
  • Stable Financial Performance: Sarepta reported total net product revenue of $331 million in Q1 2026, with PMO therapies contributing $229 million and ELEVIDYS $102 million, indicating a gradual recovery in profitability following disruptions in 2025.
  • Guidance Reaffirmation: Management reiterated its 2026 net product revenue guidance of $1.2 billion to $1.4 billion, while emphasizing that the recovery of ELEVIDYS demand will be a slow process, reflecting a cautious approach to market dynamics.
  • Cash Flow and Investments: As of the end of Q1, Sarepta held approximately $748 million in cash and investments, achieving positive cash flow excluding Arrowhead-related payments, demonstrating the company's ability to fund its pipeline without reliance on equity markets.
  • Clinical Progress and Regulation: Sarepta is advancing standard approval applications for VYONDYS and AMONDYS, with a PDUFA date expected in February next year, showcasing the company's efforts to strengthen the regulatory standing of its product portfolio.
Wall Street analysts forecast SRPT stock price to rise
18 Analyst Rating
Wall Street analysts forecast SRPT stock price to rise
4 Buy
10 Hold
4 Sell
Hold
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
Evercore ISI
In Line
to
Hold
downgrade
$20 -> $19
AI Analysis
2026-05-15
Reason
Evercore ISI
Price Target
$20 -> $19
AI Analysis
2026-05-15
downgrade
In Line
to
Hold
Reason
Evercore ISI lowered the firm's price target on Sarepta to $19 from $20 and keeps an In Line rating on the shares.
H.C. Wainwright
Mitchell Kapoor
Sell
maintain
$5
2026-04-16
Reason
H.C. Wainwright
Mitchell Kapoor
Price Target
$5
2026-04-16
maintain
Sell
Reason
H.C. Wainwright analyst Mitchell Kapoor reiterates a Sell rating on Sarepta (SRPT) with a $5 price target saying Roche's (RHHBY) new placebo-controlled Phase 3 study raises the risk that Elevidys fails the North Star Ambulatory Assessment efficacy test again. The EMBARK study already failed to show statistical significance on NSAA, and Roche is trying again, the firm points out. Roche is now putting Elevidys "back into another randomized test that could further crack the external-control argument if NSAA misses again," the analyst tells investors in a research note. H.C. Wainwright believes this creates limited upside for Sarepta and meaningful downside for the U.S. franchise that still drives the shares. Sarepta's core revenue stream is the U.S. Elevidys business, not Europe, the firm contends.
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Valuation Metrics

The current forward P/E ratio for Sarepta Therapeutics Inc (SRPT.O) is 5.42, compared to its 5-year average forward P/E of 7.34. For a more detailed relative valuation and DCF analysis to assess Sarepta Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
7.34
Current PE
5.42
Overvalued PE
44.07
Undervalued PE
-29.38

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
4.21
Current EV/EBITDA
3.20
Overvalued EV/EBITDA
89.31
Undervalued EV/EBITDA
-80.89

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.83
Current PS
1.27
Overvalued PS
8.85
Undervalued PS
2.80

Financials

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Whales Holding SRPT

V
Voleon Capital Management LP
Holding
SRPT
+14.93%
3M Return
E
Erste Asset Management GmbH
Holding
SRPT
+10.83%
3M Return
T
Tang Capital Management, LLC
Holding
SRPT
+2.01%
3M Return

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Frequently Asked Questions

What is Sarepta Therapeutics Inc (SRPT) stock price today?

The current price of SRPT is 17.87 USD — it has increased 3.29

What is Sarepta Therapeutics Inc (SRPT)'s business?

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS.

What is the price predicton of SRPT Stock?

Wall Street analysts forecast SRPT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SRPT is20.80 USD with a low forecast of 5.00 USD and a high forecast of 45.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Sarepta Therapeutics Inc (SRPT)'s revenue for the last quarter?

Sarepta Therapeutics Inc revenue for the last quarter amounts to 730.80M USD, decreased -1.89

What is Sarepta Therapeutics Inc (SRPT)'s earnings per share (EPS) for the last quarter?

Sarepta Therapeutics Inc. EPS for the last quarter amounts to 2.71 USD, decreased -158.91

How many employees does Sarepta Therapeutics Inc (SRPT). have?

Sarepta Therapeutics Inc (SRPT) has 835 emplpoyees as of June 01 2026.

What is Sarepta Therapeutics Inc (SRPT) market cap?

Today SRPT has the market capitalization of 1.89B USD.