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SRPT Overview

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Intellectia

Loading chart...

High
17.580
Open
17.540
VWAP
17.25
Vol
2.45M
Mkt Cap
1.85B
Low
16.600
Amount
42.25M
EV/EBITDA(TTM)
--
Total Shares
104.99M
EV
1.74B
EV/OCF(TTM)
--
P/S(TTM)
0.82
Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS. Its pipeline includes over 40 programs at various stages of discovery, pre-clinical and clinical development.
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Events Timeline

(ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
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link
2026-02-25 (ET)
2026-02-25
19:20:00
Sarepta Therapeutics CEO Ingram Announces Retirement
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2026-02-25
16:50:00
Sarepta Reports Q4 Revenue of $442.9M, Beating Expectations
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2026-02-24 (ET)
2026-02-24
09:20:00
Sarepta Launches Elevidys in Japan with Chugai Pharmaceutical
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News

Benzinga
5.0
03-09Benzinga
FDA CBER Head Dr. Vinay Prasad to Depart, Impact on Moderna and Rare Disease Stocks
  • Leadership Change: Dr. Vinay Prasad, head of the FDA's Center for Biologics Evaluation and Research, confirmed his departure in April, prompting market interest, particularly as Moderna's stock rises due to his controversial drug review decisions.
  • Positive Market Reaction: Analyst from William Blair noted that investors are optimistic about Prasad's exit, believing it will benefit regulatory approvals for rare disease drugs, especially those utilizing single-arm studies and external controls.
  • Potential Gains for Moderna: With Prasad's departure, Moderna's mRNA-1010 vaccine could qualify for full approval in adults aged 65 and older, potentially sparing the company from conducting an additional costly vaccine efficacy study.
  • Stock Price Increases: Following the news of Prasad's resignation, stocks of Solid Biosciences and Capricor Therapeutics rose by 12.15% and 9.07%, respectively, indicating increased market confidence in rare disease treatments.
Benzinga
8.5
03-09Benzinga
uniQure Shares Surge Following FDA Official's Departure
  • Significant Stock Surge: uniQure's shares surged 31.39% to $18.75 in premarket trading following the announcement of FDA's biologics division head Vinay Prasad's resignation, extending a 33.99% increase from Friday, indicating strong market optimism about the company's future prospects.
  • Regulatory Decision Controversy: During Prasad's tenure, he faced criticism for the FDA's rejection of uniQure's Huntington's disease gene therapy application, as the agency recommended a prospective randomized controlled study, adding regulatory uncertainty that could impact uniQure's market outlook.
  • Clinical Trial Challenges: The FDA previously indicated that uniQure could pursue accelerated approval without a placebo control due to difficulties in enrolling Huntington's disease patients, reflecting regulatory flexibility for rare diseases, yet this has sparked ongoing debates about clinical trial design.
  • Strong Market Reaction: Following the news of Prasad's departure, uniQure's shares reportedly jumped as much as 70% in after-hours trading, reflecting investor expectations for a potential easing of tensions between the company and the FDA, which could pave the way for future product approvals.
stocktwits
5.0
03-07stocktwits
FDA Vaccine Chief Vinay Prasad to Depart Agency
  • Departure Sparks Market Reaction: FDA vaccine chief Vinay Prasad is set to leave at the end of April, with shares of Moderna (MRNA) rising 3%, uniQure (QURE) soaring 50%, and Sarepta Therapeutics (SRPT) gaining 5% in after-hours trading, indicating a positive market response to his exit.
  • Controversial Tenure: During his time, Prasad faced disputes, notably refusing to consider Moderna's flu vaccine application, although the FDA later reversed its stance after Moderna agreed to conduct a follow-up study, highlighting the complexities of his drug review process.
  • FDA Scrutiny on uniQure: The FDA recently recommended that uniQure conduct a sham-surgery-controlled study for its gene therapy targeting Huntington's disease, illustrating the challenges Prasad faced in drug evaluations and the tension with companies affecting their R&D timelines.
  • Policy Implementation Completed: Prasad's departure is attributed to the completion of all policies he aimed to implement, including a new priority program to expedite application reviews for treatments meeting national priorities, indicating that his objectives at the FDA have largely been achieved.
CNBC
9.0
03-06CNBC
FDA Rejects Multiple Experimental Drug Applications, Raising Investor Concerns
  • FDA Drug Rejections: The U.S. FDA has denied or discouraged applications for at least eight drugs over the past year, including UniQure's gene therapy for Huntington's disease, indicating regulatory uncertainty that could impact future treatment approvals.
  • Investor Concerns Rise: Investors are increasingly wary as the FDA appears to change its standards for drug applications, particularly for treatments targeting hard-to-treat diseases, leading to diminished confidence in ongoing development efforts.
  • Changing Regulatory Standards: The FDA's request for UniQure to conduct new placebo-controlled trials contradicts previous guidance, highlighting inconsistencies in the agency's approval process that may create uncertainty for companies in their R&D efforts.
  • Uncertain Future Outlook: Analysts warn that if the FDA does not approve Denali Therapeutics' drug for Hunter syndrome, it could further undermine other companies' confidence in running open-label studies, potentially stifling innovation across the industry.
CNBC
7.0
03-03CNBC
FDA Faces Criticism Amid Innovation Challenges
  • Regulatory Standards Controversy: Congressman Jake Auchincloss criticized FDA Commissioner Marty Makary for replacing standards of safety and efficacy with fear and favoritism, undermining patient confidence in new therapies and impacting the market launch of innovative drugs.
  • Staffing Losses: The FDA has experienced significant staff reductions in its Center for Drug Evaluation and Research, with oncology review staff dropping from about 100 to below 60, which may lead to approval delays and incomplete response letters.
  • Decline in Accelerated Approvals: In 2024, the FDA approved 20 drugs through the accelerated approval process, down from 9 the previous year, indicating a direct impact on drug approval efficiency due to the loss of experienced reviewers.
  • New Therapy Approval Pathways: The FDA proposed a new system for approving personalized drugs aimed at rare diseases, intending to provide more flexible approval pathways, but this change has sparked widespread controversy, affecting the agency's core mission.
Newsfilter
8.5
02-27Newsfilter
Sarepta Launches Duchenne Scholarship Program for 2026-2027
  • Scholarship Program Launch: Sarepta Therapeutics has announced the opening of the Route 79 Duchenne Scholarship Program for the 2026-2027 academic year, offering scholarships of up to $5,000 to as many as 20 individuals living with Duchenne muscular dystrophy and five siblings, aimed at supporting the educational aspirations of this unique community.
  • Clear Application Criteria: Applicants must be accepted to or enrolled in an accredited college or vocational school in the U.S. and must be diagnosed with Duchenne or have a sibling diagnosed with the condition, ensuring fairness and targeted support for educational opportunities.
  • Independent Review Process: Scholarship recipients are selected by an independent committee, which evaluates applications without considering whether the applicant has received treatment from Sarepta, thereby enhancing the program's credibility and transparency in the selection process.
  • Historical Impact: Since its inception nine years ago, the Route 79 Scholarship Program has empowered numerous young individuals to pursue their academic dreams, reflecting Sarepta's ongoing commitment to supporting those affected by Duchenne muscular dystrophy and reinforcing its leadership position in precision genetic medicine.
Wall Street analysts forecast SRPT stock price to rise
18 Analyst Rating
Wall Street analysts forecast SRPT stock price to rise
4 Buy
10 Hold
4 Sell
Hold
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
Citi
NULL -> Sell
downgrade
$8 -> $9
AI Analysis
2026-03-10
New
Reason
Citi
Price Target
$8 -> $9
AI Analysis
2026-03-10
New
downgrade
NULL -> Sell
Reason
Citi raised the firm's price target on Sarepta to $9 from $8 and keeps a Sell rating on the shares. The firm updated the company's model post the Q4 report.
Wedbush
Yun Zhong
Outperform
downgrade
$34 -> $29
2026-03-02
Reason
Wedbush
Yun Zhong
Price Target
$34 -> $29
2026-03-02
downgrade
Outperform
Reason
Wedbush analyst Yun Zhong lowered the firm's price target on Sarepta to $29 from $34 and keeps an Outperform rating on the shares. The firm says the Q4 revenue provided no surprises after the pre-announcement in January, but management's 2026 revenue guidance was likely below the Street's expectations. Wedbush's optimism in both Elevidys and PMO products is unchanged, but the firm has adjusted its revenue projection based on the above guidance.
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Valuation Metrics

The current forward P/E ratio for Sarepta Therapeutics Inc (SRPT.O) is 89.24, compared to its 5-year average forward P/E of 6.53. For a more detailed relative valuation and DCF analysis to assess Sarepta Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
6.53
Current PE
89.24
Overvalued PE
44.24
Undervalued PE
-31.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
4.17
Current EV/EBITDA
27.78
Overvalued EV/EBITDA
90.88
Undervalued EV/EBITDA
-82.54

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
6.34
Current PS
1.46
Overvalued PS
9.18
Undervalued PS
3.50

Financials

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Whales Holding SRPT

T
Tang Capital Management, LLC
Holding
SRPT
+2.62%
3M Return
V
Voleon Capital Management LP
Holding
SRPT
-0.60%
3M Return

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Frequently Asked Questions

What is Sarepta Therapeutics Inc (SRPT) stock price today?

The current price of SRPT is 17.575 USD — it has decreased -0.48

What is Sarepta Therapeutics Inc (SRPT)'s business?

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS. Its pipeline includes over 40 programs at various stages of discovery, pre-clinical and clinical development.

What is the price predicton of SRPT Stock?

Wall Street analysts forecast SRPT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SRPT is20.80 USD with a low forecast of 5.00 USD and a high forecast of 45.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Sarepta Therapeutics Inc (SRPT)'s revenue for the last quarter?

Sarepta Therapeutics Inc revenue for the last quarter amounts to 442.93M USD, decreased -32.73

What is Sarepta Therapeutics Inc (SRPT)'s earnings per share (EPS) for the last quarter?

Sarepta Therapeutics Inc. EPS for the last quarter amounts to -2.70 USD, decreased -304.55

How many employees does Sarepta Therapeutics Inc (SRPT). have?

Sarepta Therapeutics Inc (SRPT) has 835 emplpoyees as of March 12 2026.

What is Sarepta Therapeutics Inc (SRPT) market cap?

Today SRPT has the market capitalization of 1.85B USD.