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SRPT Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
20.980
Open
20.040
VWAP
20.24
Vol
1.20M
Mkt Cap
2.11B
Low
19.860
Amount
24.28M
EV/EBITDA(TTM)
10.23
Total Shares
105.58M
EV
2.29B
EV/OCF(TTM)
13.08
P/S(TTM)
0.99
Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS.
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Events Timeline

(ET)
2026-05-11
12:30:00
Trump Approves Firing of FDA Commissioner Makary
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link
2026-05-11
10:20:00
Trump Plans to Fire FDA Commissioner, Biotech Stocks Affected
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2026-05-08 (ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
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2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
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link
2026-05-06 (ET)
2026-05-06
17:20:00
Sarepta Therapeutics Q1 Revenue Reaches $730.8M
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News

stocktwits
6.5
05-08stocktwits
FDA Leadership Shakeup May Impact Biotech Stocks
  • Stock Price Surge: Following reports of potential dismissal of FDA Commissioner Marty Makary, shares of Replimune (REPL) and uniQure (QURE) surged by 17% and 15% respectively, indicating market optimism regarding regulatory improvements under new leadership.
  • Industry Response: The pharmaceutical industry has expressed dissatisfaction with Makary's drug review policies, citing inconsistencies and overly restrictive processes that hinder innovative drug approvals, suggesting that new leadership could accelerate approval timelines and restore clearer regulatory guidance.
  • Potential Beneficiaries: Companies like Replimune and uniQure, which have publicly clashed with the FDA, are seen as potential beneficiaries of new leadership, with Replimune's melanoma therapy RP1 being rejected and uniQure's Huntington's disease gene therapy AMT-130 facing significant shifts in review policy.
  • Market Reaction: Despite REPL's stock falling approximately 50% over the past year, QURE's stock has risen by 124%, reflecting investor confidence in the future of the biotech sector and expectations for changes in FDA policies.
seekingalpha
9.5
05-07seekingalpha
Sarepta Therapeutics Q1 2026 Earnings Call Insights
  • Stable Financial Performance: Sarepta reported total net product revenue of $331 million in Q1 2026, with PMO therapies contributing $229 million and ELEVIDYS $102 million, indicating a gradual recovery in profitability following disruptions in 2025.
  • Guidance Reaffirmation: Management reiterated its 2026 net product revenue guidance of $1.2 billion to $1.4 billion, while emphasizing that the recovery of ELEVIDYS demand will be a slow process, reflecting a cautious approach to market dynamics.
  • Cash Flow and Investments: As of the end of Q1, Sarepta held approximately $748 million in cash and investments, achieving positive cash flow excluding Arrowhead-related payments, demonstrating the company's ability to fund its pipeline without reliance on equity markets.
  • Clinical Progress and Regulation: Sarepta is advancing standard approval applications for VYONDYS and AMONDYS, with a PDUFA date expected in February next year, showcasing the company's efforts to strengthen the regulatory standing of its product portfolio.
stocktwits
9.5
05-06stocktwits
Sarepta's Q1 Results Beat Expectations but Shares Drop
  • Strong Performance: Sarepta Therapeutics reported Q1 total revenue of $730.8 million, which, despite a 2% year-over-year decline, exceeded market expectations of $475.01 million, demonstrating resilience in revenue generation.
  • Adjusted EPS Improvement: The company posted an adjusted earnings per share of $3.16, a significant recovery from a loss of $3.42 in the same quarter last year, and comfortably above the analyst estimate of $1.09, indicating a marked improvement in profitability.
  • Decline in Elevidys Sales: Elevidys generated $102 million in net product sales, a sharp drop from $375 million in Q1 2025, primarily due to safety concerns limiting the addressable patient population, which adversely affected the company's core business.
  • Future Guidance: Sarepta reiterated its full-year 2026 guidance for total net product revenue between $1.2 billion and $1.4 billion, and despite challenges, CEO Doug Ingram expressed optimism about the stabilization of the company's commercial portfolio and the growth potential of Elevidys.
seekingalpha
9.5
05-06seekingalpha
Sarepta Therapeutics Q1 Results Beat Expectations Despite Stock Decline
  • Strong Financial Performance: Sarepta Therapeutics reported a non-GAAP EPS of $3.16 for Q1, beating expectations by $2.11, indicating an improvement in profitability despite a year-over-year revenue decline.
  • Revenue Guidance Adjustment: The company projects net product revenues for 2026 to be between $1.2 billion and $1.4 billion, falling short of the consensus estimate of $1.73 billion, reflecting market caution regarding future growth.
  • Significant R&D Expense Reduction: R&D expenses for the quarter were $154 million, a substantial decrease from $773.4 million year-over-year, demonstrating effective cost control measures that have positively impacted overall financial health.
  • Cash Flow Status: As of the end of the quarter, the company had cash, cash equivalents, restricted cash, and investments totaling $748.3 million, down from $953.8 million on December 31, 2025, indicating a tightening of cash resources.
seekingalpha
9.5
05-06seekingalpha
Sarepta Therapeutics Q1 Earnings Exceed Expectations
  • Strong Earnings Performance: Sarepta Therapeutics reported a Q1 non-GAAP EPS of $3.16, beating expectations by $2.11, which reflects a significant enhancement in profitability and boosts investor confidence.
  • Robust Revenue Growth: The company achieved Q1 revenue of $730.8 million, a slight decline of 1.9% year-over-year, yet it surpassed market expectations by $255.79 million, indicating a stable revenue performance in a competitive market.
  • Substantial Operating Income: Sarepta's GAAP and non-GAAP operating income for Q1 stood at $358.4 million and $397.7 million, respectively, showcasing successful cost control and operational efficiency, further solidifying its market position.
  • siRNA Pipeline Progress: Preliminary Phase 1/2 data for SRP-1001 and SRP-1003 demonstrate dose-dependent drug exposure, early biomarker effects, and favorable tolerability, suggesting potential breakthroughs in the treatment of muscle diseases.
Newsfilter
9.5
04-22Newsfilter
Sarepta Therapeutics to Report Q1 2026 Financial Results
  • Earnings Release Schedule: Sarepta Therapeutics is set to announce its Q1 2026 financial results after the Nasdaq Global Market closes on May 6, 2026, which is expected to provide investors with critical financial data and future outlook.
  • Conference Call Details: Following the earnings release, Sarepta will host a conference call at 4:30 p.m. E.T. to discuss the financial results, with phone participants required to register in advance to obtain dial-in information, ensuring smooth communication of important updates.
  • Investor Relations Focus: The company emphasizes transparency and investor communication by offering a live webcast and a one-year replay on its investor relations website, aiming to bolster investor confidence and engagement.
  • Company Mission and Vision: Sarepta is committed to developing precision genetic medicine for rare diseases, particularly leading in Duchenne muscular dystrophy, showcasing its strong R&D capabilities across muscle, central nervous system, and cardiac diseases.
Wall Street analysts forecast SRPT stock price to rise
18 Analyst Rating
Wall Street analysts forecast SRPT stock price to rise
4 Buy
10 Hold
4 Sell
Hold
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
Current: 0.000
sliders
Low
5.00
Averages
20.80
High
45.00
H.C. Wainwright
Mitchell Kapoor
Sell
maintain
$5
AI Analysis
2026-04-16
Reason
H.C. Wainwright
Mitchell Kapoor
Price Target
$5
AI Analysis
2026-04-16
maintain
Sell
Reason
H.C. Wainwright analyst Mitchell Kapoor reiterates a Sell rating on Sarepta (SRPT) with a $5 price target saying Roche's (RHHBY) new placebo-controlled Phase 3 study raises the risk that Elevidys fails the North Star Ambulatory Assessment efficacy test again. The EMBARK study already failed to show statistical significance on NSAA, and Roche is trying again, the firm points out. Roche is now putting Elevidys "back into another randomized test that could further crack the external-control argument if NSAA misses again," the analyst tells investors in a research note. H.C. Wainwright believes this creates limited upside for Sarepta and meaningful downside for the U.S. franchise that still drives the shares. Sarepta's core revenue stream is the U.S. Elevidys business, not Europe, the firm contends.
RBC Capital
Sector Perform
maintain
$18 -> $19
2026-04-07
Reason
RBC Capital
Price Target
$18 -> $19
2026-04-07
maintain
Sector Perform
Reason
RBC Capital raised the firm's price target on Sarepta to $19 from $18 and keeps a Sector Perform rating on the shares as part of the firm's broader research note previewing Q1 results in Biotech. Seasonal headwinds around gross/net, reimbursement resets, and fewer selling days may be exacerbated in Q1 by weather impact, particularly for launching and in-clinic products, but the robust return of M&A, coupled with clarity on limited tariff/Most Favored Nation drug pricing impacts, could help offset both this and broader macro volatility while keeping sector perceptions favorable, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SRPT
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Valuation Metrics

The current forward P/E ratio for Sarepta Therapeutics Inc (SRPT.O) is 5.76, compared to its 5-year average forward P/E of 7.15. For a more detailed relative valuation and DCF analysis to assess Sarepta Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
7.15
Current PE
5.76
Overvalued PE
43.95
Undervalued PE
-29.65

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
4.05
Current EV/EBITDA
3.70
Overvalued EV/EBITDA
89.20
Undervalued EV/EBITDA
-81.11

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.92
Current PS
1.53
Overvalued PS
8.92
Undervalued PS
2.91

Financials

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Whales Holding SRPT

E
Erste Asset Management GmbH
Holding
SRPT
+8.88%
3M Return
T
Tang Capital Management, LLC
Holding
SRPT
+3.72%
3M Return

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Frequently Asked Questions

What is Sarepta Therapeutics Inc (SRPT) stock price today?

The current price of SRPT is 19.865 USD — it has decreased -0.45

What is Sarepta Therapeutics Inc (SRPT)'s business?

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS.

What is the price predicton of SRPT Stock?

Wall Street analysts forecast SRPT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SRPT is20.80 USD with a low forecast of 5.00 USD and a high forecast of 45.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Sarepta Therapeutics Inc (SRPT)'s revenue for the last quarter?

Sarepta Therapeutics Inc revenue for the last quarter amounts to 730.80M USD, decreased -1.89

What is Sarepta Therapeutics Inc (SRPT)'s earnings per share (EPS) for the last quarter?

Sarepta Therapeutics Inc. EPS for the last quarter amounts to 2.71 USD, decreased -158.91

How many employees does Sarepta Therapeutics Inc (SRPT). have?

Sarepta Therapeutics Inc (SRPT) has 835 emplpoyees as of May 11 2026.

What is Sarepta Therapeutics Inc (SRPT) market cap?

Today SRPT has the market capitalization of 2.11B USD.