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ONC Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
294.300
Open
293.300
VWAP
289.92
Vol
174.82K
Mkt Cap
32.01B
Low
287.530
Amount
50.68M
EV/EBITDA(TTM)
52.38
Total Shares
111.17M
EV
221.98B
EV/OCF(TTM)
16.19
P/S(TTM)
9.51
BeOne Medicines AG, formerly BeiGene, Ltd., is a global oncology company engaged in discovering and developing treatments for cancer patients worldwide. With a portfolio spanning hematology and solid tumors, the Company is engaged in the development of its diverse pipeline of novel therapeutics. Its products include Brukinsa, Tevimbra and Pamiparib. Brukinsa is an orally available, small-molecule inhibitor of Bruton’s tyrosine kinase (BTK). Tevimbra is a humanized immunoglobulin G4 (IgG4) anti-programmed cell death protein 1 (PD-1) monoclonal antibody with high affinity and binding specificity against PD-1. It is designed to minimize binding to Fc-gamma (Fcy) receptors on macrophages, helping the body’s immune cells detect and fight tumors. The Company’s product pipeline in development includes Sonrotoclax, Tarlatamab, Zanidatamab, Blinatumomab, BGB-26808, BGB-R046, BG-68501, BG-C9074, BGB-43395, Xaluritamig, and others.
Show More

Events Timeline

(ET)
2026-05-27
17:10:00
BeOne Medicines Announces HERIZON-GEA-01 Trial Data
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2026-05-13 (ET)
2026-05-13
13:30:00
BeOne Medicines Receives FDA Accelerated Approval for Beqalzi to Treat Lymphoma
select
2026-05-06 (ET)
2026-05-06
06:30:00
BeOne Q1 Revenue Hits $1.51B, Exceeds Expectations
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2026-05-06
06:30:00
BeOne Sets 2026 Total Revenue Guidance at $6.3B to $6.5B
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News

Newsfilter
8.5
05-27Newsfilter
PinnedTEVIMBRA and ZIIHERA Combination Therapy Significantly Improves Survival Rates
  • Significant Survival Improvement: The HERIZON-GEA-01 trial demonstrated that the combination of TEVIMBRA and ZIIHERA with chemotherapy achieved a median overall survival of 26.4 months, compared to 19.2 months in the control group, indicating the potential importance of this combination in treating HER2+ gastroesophageal adenocarcinoma.
  • Effective Regardless of PD-L1 Status: Results showed that this combination therapy provided significant survival benefits in both PD-L1 positive and negative patients, particularly in those with PD-L1 <1%, where the median survival was 29.7 months, far exceeding the control group's 15.8 months, highlighting its broad applicability.
  • Strong Durability of Response: The median duration of response for the ZIIHERA and TEVIMBRA combination was 20.7 months, significantly longer than the 14.3 months for ZIIHERA alone and 8.3 months for the control group, underscoring the clinical significance of this combination in prolonging patient survival.
  • Regulatory Progress: The U.S. FDA has accepted a supplemental Biologics License Application for TEVIMBRA with priority review, and the Chinese NMPA has also accepted applications for ZIIHERA and TEVIMBRA, indicating that this combination therapy is poised for rapid approval in multiple markets.
Newsfilter
2.0
05-29Newsfilter
BeOne's Drug Shows New Breakthroughs in CLL Treatment
  • Long-Term Efficacy Data: The SEQUOIA study indicates that BRUKINSA shows a progression-free survival (PFS) of 71.8% after a median follow-up of 84.01 months, significantly outperforming the 31.0% PFS of the BR group, highlighting its long-term efficacy in first-line treatment for chronic lymphocytic leukemia (CLL).
  • Real-World Evidence: An analysis of 10,523 CLL/SLL patients treated with BTK inhibitors revealed that BRUKINSA significantly reduced the risk of death and treatment discontinuation, further solidifying its position as the best-in-class BTK inhibitor.
  • Combination Therapy Potential: The combination of BRUKINSA with the next-generation BCL2 inhibitor sonrotoclax demonstrated an unprecedented overall response rate of 100% and a complete response rate of 59.5% in high-risk CLL patients, indicating a promising direction for time-limited treatments.
  • Safety Consistency: The safety profile of BRUKINSA remains consistent with previous studies, with no new safety signals identified, ensuring its sustainability and patient confidence in clinical applications.
Newsfilter
1.0
05-26Newsfilter
BeOne Medicines to Participate in Goldman Sachs Healthcare Conference
  • Conference Participation: BeOne Medicines will participate in the Goldman Sachs 47th Annual Global Healthcare Conference on June 8, 2026, featuring a fireside chat at 10:00 a.m. EDT, showcasing its latest advancements in oncology treatments.
  • Live Webcast Details: The event will be accessible via a live webcast from the investor section of the company's website, ensuring global investors can stay updated in real-time, with an archived version available post-event to enhance information transparency.
  • Company Overview: BeOne Medicines is a global oncology company focused on developing innovative treatments for cancer patients, with a portfolio that spans hematology and solid tumors, indicating a broad strategic focus in the oncology sector.
  • Global Team Expansion: The company boasts a growing global team across six continents, dedicated to scientific excellence and rapid response, reflecting its strategic importance in delivering treatments to patients more efficiently worldwide.
Newsfilter
8.5
05-21Newsfilter
BeOne Medicines Showcases New Advances at ASCO
  • Foundation in CLL: At ASCO and EHA 2026, BeOne showcased 78-month follow-up data from the SEQUOIA trial, reinforcing BRUKINSA® as the foundational BTK inhibitor in chronic lymphocytic leukemia (CLL), demonstrating durable disease control that raises expectations for first-line therapy among patients and physicians.
  • Elderly Patient Analysis: A subgroup analysis from the SEQUOIA trial revealed that patients aged ≥80 years also benefited from treatment, indicating that age does not limit therapeutic efficacy, thereby solidifying BeOne's position in treating older patient populations.
  • New Drug Presentation: The oral presentation of BeOne's BTK degrader BGB-16673 at EHA 2026 highlighted promising durability and manageable safety in relapsed/refractory CLL patients, with previously unreported data in BTK-naïve patients generating significant interest.
  • Solid Tumor Pipeline Acceleration: BeOne demonstrated strong momentum in its solid tumor pipeline at ASCO, featuring seven unique assets, emphasizing the differentiated profile of PD-1 inhibitor TEVIMBRA® across lung and gastrointestinal cancers, showcasing its potential in areas of high unmet medical need.
Newsfilter
7.5
05-20Newsfilter
BeOne Launches Soccer Campaign to Enhance Cancer Care
  • Campaign Launch: BeOne Medicines has initiated the 'One Save Changes Everything' campaign, leveraging soccer to enhance the scientific, clinical, and human aspects of cancer care, supported by former U.S. National Team goalkeeper Tim Howard, highlighting the company's commitment to patients.
  • Community Commitment: BeOne is investing $300,000 in partnership with the U.S. Soccer Foundation to install soccer mini-pitches near cancer treatment centers, aiming to create spaces for movement and connection for families affected by cancer, thereby improving patients' quality of life.
  • Employee Engagement: With over 12,000 employees, BeOne will convert volunteer hours into charitable donations during the campaign, further supporting the U.S. Soccer Foundation and other nonprofits, reflecting the company's dedication to social responsibility.
  • Global Reach: The campaign will not only focus on the U.S. but also attract more international goalkeepers and voices from the cancer community, showcasing BeOne's global influence and ongoing commitment to advancing cancer care worldwide.
stocktwits
9.0
05-13stocktwits
BeOne's Drug Receives FDA Accelerated Approval
  • FDA Accelerated Approval: BeOne's BEQALZI receives FDA accelerated approval, marking the first new B-cell lymphoma 2 inhibitor approved in nearly a decade, which signifies a major advancement in treating relapsed or refractory mantle cell lymphoma and is expected to enhance the company's market competitiveness.
  • Clinical Data Support: The drug demonstrated a 52% overall response rate and a 16% complete response rate in clinical trials, with a median duration of response of 15.8 months, indicating strong performance in terms of efficacy and tolerability, potentially attracting more patients to its use.
  • Market Potential: With approximately 3,300 new mantle cell lymphoma patients diagnosed annually in the U.S., the approval of BEQALZI provides a new treatment option for these patients, likely driving BeOne's market share growth in the oncology sector.
  • Regulatory Follow-Up: Despite the accelerated approval, BeOne stated that continued approval will depend on the results of confirmatory trials, indicating that the company must continue to invest resources to ensure long-term market compliance for the drug.
Wall Street analysts forecast ONC stock price to rise
11 Analyst Rating
Wall Street analysts forecast ONC stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
385.00
Averages
403.76
High
424.00
Current: 0.000
sliders
Low
385.00
Averages
403.76
High
424.00
Leerink
NULL
to
Outperform
maintain
$364 -> $367
AI Analysis
2026-05-15
Reason
Leerink
Price Target
$364 -> $367
AI Analysis
2026-05-15
maintain
NULL
to
Outperform
Reason
Leerink raised the firm's price target on BeOne Medicines to $367 from $364 and keeps an Outperform rating on the shares. The firm notes the company announced that the FDA has granted sonrotoclax accelerated approval in relapse/refractory mantle cell lymphoma. This is the first approval for sonrotoclax with additional trials ongoing in relapsed or refractory mantle cell lymphoma in combination with zanubrutinib, in R/R chronic lymphocytic leukemia / small lymphocytic lymphoma in combination with anti-CD20 antibodies, and treatment-naive chronic lymphocytic leukemia in combination with zanubrutinib.
Morgan Stanley
NULL
to
Overweight
maintain
$389 -> $395
2026-05-07
Reason
Morgan Stanley
Price Target
$389 -> $395
2026-05-07
maintain
NULL
to
Overweight
Reason
Morgan Stanley raised the firm's price target on BeOne Medicines to $395 from $389 and keeps an Overweight rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ONC
Unlock Now

Valuation Metrics

The current forward P/E ratio for BeOne Medicines AG (ONC.O) is 47.17, compared to its 5-year average forward P/E of 71.19. For a more detailed relative valuation and DCF analysis to assess BeOne Medicines AG's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
71.19
Current PE
47.17
Overvalued PE
134.97
Undervalued PE
7.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
27.06
Current EV/EBITDA
17.10
Overvalued EV/EBITDA
62.33
Undervalued EV/EBITDA
-8.21

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.71
Current PS
4.06
Overvalued PS
6.70
Undervalued PS
4.72

Financials

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Whales Holding ONC

P
PRIMECAP Management Company
Holding
ONC
+25.36%
3M Return
B
Bluebox Asset Management Uk Ltd.
Holding
ONC
+24.26%
3M Return
G
Guotai Asset Management Company Limited
Holding
ONC
+23.21%
3M Return
F
Franklin Templeton Sealand Fund Management Co., Ltd.
Holding
ONC
+20.22%
3M Return
G
GF Fund Management Co., Ltd.
Holding
ONC
+15.33%
3M Return
B
Bosera Asset Management Co., Ltd.
Holding
ONC
+13.63%
3M Return

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Frequently Asked Questions

What is BeOne Medicines AG (ONC) stock price today?

The current price of ONC is 287.92 USD — it has decreased -0.92

What is BeOne Medicines AG (ONC)'s business?

BeOne Medicines AG, formerly BeiGene, Ltd., is a global oncology company engaged in discovering and developing treatments for cancer patients worldwide. With a portfolio spanning hematology and solid tumors, the Company is engaged in the development of its diverse pipeline of novel therapeutics. Its products include Brukinsa, Tevimbra and Pamiparib. Brukinsa is an orally available, small-molecule inhibitor of Bruton’s tyrosine kinase (BTK). Tevimbra is a humanized immunoglobulin G4 (IgG4) anti-programmed cell death protein 1 (PD-1) monoclonal antibody with high affinity and binding specificity against PD-1. It is designed to minimize binding to Fc-gamma (Fcy) receptors on macrophages, helping the body’s immune cells detect and fight tumors. The Company’s product pipeline in development includes Sonrotoclax, Tarlatamab, Zanidatamab, Blinatumomab, BGB-26808, BGB-R046, BG-68501, BG-C9074, BGB-43395, Xaluritamig, and others.

What is the price predicton of ONC Stock?

Wall Street analysts forecast ONC stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ONC is403.76 USD with a low forecast of 385.00 USD and a high forecast of 424.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is BeOne Medicines AG (ONC)'s revenue for the last quarter?

BeOne Medicines AG revenue for the last quarter amounts to 1.51B USD, increased 35.46

What is BeOne Medicines AG (ONC)'s earnings per share (EPS) for the last quarter?

BeOne Medicines AG. EPS for the last quarter amounts to 0.15 USD, decreased

How many employees does BeOne Medicines AG (ONC). have?

BeOne Medicines AG (ONC) has 12000 emplpoyees as of May 30 2026.

What is BeOne Medicines AG (ONC) market cap?

Today ONC has the market capitalization of 32.01B USD.