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ONC Should I Buy

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Intellectia

Should You Buy BeOne Medicines AG (ONC) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
312.120
1 Day change
-1.54%
52 Week Range
385.220
Analysis Updated At
2026/04/24
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BeOne Medicines AG (ONC) is not a strong buy for a beginner investor with a long-term focus at this time. While the company has a strong product pipeline and some positive analyst sentiment, the lack of recent positive news, declining financial performance, and hedge fund selling trends suggest caution. Additionally, technical indicators and options data do not provide a compelling entry point currently.

Technical Analysis

The MACD is positive but contracting, RSI is neutral at 30.648, and moving averages are converging, indicating no clear trend. The stock is trading below the pivot level of 313.427, with key support at 302.066 and resistance at 324.788. Overall, the technical indicators suggest a neutral stance.

Options Data

Bearish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

The high put-call volume ratio indicates bearish sentiment in the options market, with significantly higher put volume compared to call volume.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
2
Buy
9

Positive Catalysts

  • Analysts highlight a strong product pipeline, including Brukinsa, and potential momentum from deal activity in the biotech sector. Recent price target increases from Guggenheim, RBC Capital, and Barclays reflect some optimism.

Neutral/Negative Catalysts

  • Hedge funds are aggressively selling the stock, with a 7307.41% increase in selling activity. Financial performance has deteriorated significantly, with net income and EPS showing sharp declines. No recent news or congress trading data to provide additional support.

Financial Performance

In Q3 2025, revenue grew by 41% YoY to $1.41 billion, but net income dropped by -202.88% YoY to $124.84 million, and EPS fell by -188.89% YoY to 0.08. Gross margin improved slightly to 86.09%. The financial performance indicates revenue growth but significant profitability challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have mixed views. Truist and Wolfe Research maintain positive ratings with price targets of $411 and $340, respectively, citing strong product potential. However, Jefferies downgraded the stock to Hold with a price target of $290, citing limited upside and slower growth for future assets.

Wall Street analysts forecast ONC stock price to rise
11 Analyst Rating
Wall Street analysts forecast ONC stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 317.000
sliders
Low
385
Averages
403.76
High
424
Current: 317.000
sliders
Low
385
Averages
403.76
High
424
Morgan Stanley
NULL
to
Overweight
maintain
$389 -> $395
AI Analysis
2026-05-07
New
Reason
Morgan Stanley
Price Target
$389 -> $395
AI Analysis
2026-05-07
New
maintain
NULL
to
Overweight
Reason
Morgan Stanley raised the firm's price target on BeOne Medicines to $395 from $389 and keeps an Overweight rating on the shares.
Guggenheim
Michael Schmidt
Buy
maintain
$410 -> $420
2026-05-07
New
Reason
Guggenheim
Michael Schmidt
Price Target
$410 -> $420
2026-05-07
New
maintain
Buy
Reason
Guggenheim analyst Michael Schmidt raised the firm's price target on BeOne Medicines to $420 from $410 and keeps a Buy rating on the shares after the company reported a topline beat in Q1 accompanied by a raise of 2026 guidance. The firm is updating its model to reflect Q1 results and guidance, calling BeOne its mid-cap top pick.
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