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MAIA Overview

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Intellectia

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High
1.440
Open
1.350
VWAP
1.39
Vol
661.36K
Mkt Cap
85.55M
Low
1.330
Amount
921.50K
EV/EBITDA(TTM)
--
Total Shares
60.67M
EV
73.25M
EV/OCF(TTM)
--
P/S(TTM)
--
MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer. The Company's THIO (6-thio-dG, 6-thio-2'-deoxyguanosine), is a lead asset, is an investigational dual mechanism of action drug candidate incorporating telomere targeting and immunogenicity. The modified nucleotide 6-thio-2-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in tumor regression in advanced, in vivo cancer models by induction of cancer type-specific immune memory. THIO is being developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors.
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Events Timeline

(ET)
2026-04-08
09:30:00
MAIA Biotechnology Completes $33M Offering to Fund Lung Cancer Trial
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2026-03-02 (ET)
2026-03-02
17:10:00
MAIA Biotechnology Launches Underwritten Public Offering
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2026-02-24 (ET)
2026-02-24
08:50:00
MAIA Biotechnology Releases 2026 Shareholder Letter Highlighting Drug Development Progress
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2026-01-20 (ET)
2026-01-20
10:30:00
MAIA Targets 2026: Strong Clinical Data for Ateganosine
select
2025-12-16 (ET)
2025-12-16
16:30:00
MAIA Biotechnology Issues 1.233M Shares at $1.224 Each
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2025-12-16
16:20:00
MAIA Biotechnology Sells 1.23M Shares at $1.224 Each
select
2025-12-11 (ET)
2025-12-11
09:20:00
MAIA Biotechnology Doses First Patient in THIO-104 Phase 3 Trial
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News

Newsfilter
2.0
04-16Newsfilter
MAIA Biotechnology Reports Progress in THIO-101 Clinical Trial for NSCLC
  • Clinical Trial Launch: MAIA Biotechnology has activated the first clinical site for its THIO-101 expansion trial in the U.S., expected to provide new treatment options for approximately 50,000 patients with resistant non-small cell lung cancer annually, significantly enhancing the company's market position in cancer immunotherapy.
  • Funding Support: The trial is backed by a $2.3 million grant from the National Institutes of Health (NIH), underscoring the research value and potential market impact of the project, thereby strengthening MAIA's financing capabilities in the competitive biopharmaceutical industry.
  • Exceptional Efficacy Data: THIO-101 demonstrated outstanding efficacy data in 2025, with overall survival exceeding 24 months, far surpassing existing treatment standards, indicating the drug's potential to become a best-in-class option in non-small cell lung cancer treatment.
  • FDA Fast Track Designation: MAIA's lead drug has received FDA Fast Track designation, which accelerates the development and review process for serious conditions, and if criteria are met, it may qualify for FDA Accelerated Approval and Priority Review, further enhancing its competitive edge in the market.
NASDAQ.COM
8.5
04-09NASDAQ.COM
MAIA Biotechnology Raises $33 Million to Advance Clinical Trials
  • Funding Boosts Clinical Trials: MAIA Biotechnology has secured $33 million in funding, ensuring full financial support for its pivotal Phase 3 trial of Ateganosine (THIO) in non-small cell lung cancer (NSCLC), thereby solidifying the company's clinical ambitions in the oncology sector.
  • Innovative Drug Mechanism: Ateganosine targets telomeres, damaging cancer cell DNA and activating the immune system, with earlier studies indicating rapid and durable tumor regression, potentially positioning it as the first-in-class telomere-targeting therapy for patients with limited treatment options.
  • THIO-104 Trial Design: The THIO-104 trial is a global, multicenter, open-label study evaluating the efficacy of Ateganosine in combination with a checkpoint inhibitor, aiming to enroll up to 300 patients and primarily assess overall survival, making it a critical test against standard chemotherapy.
  • Significant Market Potential: Lung cancer remains a leading cause of cancer deaths worldwide, and Ateganosine could provide new treatment options for patients who progress after chemotherapy and immunotherapy, enhancing survival rates and quality of life, aligning with MAIA's mission.
seekingalpha
8.5
04-08seekingalpha
MAIA Biotechnology Secures $33 Million for Phase 3 Trial
  • Clear Funding Purpose: MAIA Biotechnology announced that the net proceeds from its $33 million public offering will fully fund its ongoing pivotal Phase 3 clinical trial for its lead investigational drug, ateganosine, targeting non-small cell lung cancer (NSCLC), demonstrating the company's strong commitment to research and development.
  • Innovative Drug Mechanism: Ateganosine is designed as a dual mechanism therapy that aims to break down telomere structure and function in cancer cells while inducing immune activation, potentially providing new treatment options for NSCLC patients and enhancing the company's competitiveness in oncology.
  • FDA Fast Track Designation: The U.S. Food and Drug Administration has granted Fast Track designation for ateganosine in third-line NSCLC treatment, which not only accelerates the drug's development process but also may provide the company with quicker market access opportunities.
  • Positive Market Reaction: Following the public offering announcement, MAIA's stock price rose 5.0% in pre-market trading to $1.26, reflecting investor confidence in the company's future prospects and expectations for the success of its clinical trial.
NASDAQ.COM
8.5
04-03NASDAQ.COM
Biotech Landscape Update: Regulatory Approvals and Acquisitions
  • ARS Pharma Expands Neffy Label: ARS Pharmaceuticals received FDA approval to update the Neffy 1mg label, removing age restrictions for individuals weighing over 33 lbs, which is expected to significantly boost market demand and enhance the company's competitive edge in allergy treatment.
  • Novo Nordisk Wins Approval for Awiqli: Novo Nordisk's Awiqli (insulin icodec-abae) received FDA approval as the first once-weekly basal insulin, with a U.S. launch planned for 2H 2026, strengthening the company's leadership in diabetes care.
  • Biogen Acquires Apellis: Biogen has agreed to acquire Apellis for $41 per share, valuing the deal at approximately $5.6 billion, which is expected to enhance its market share in immunology and rare diseases while driving future revenue growth.
  • Takeda's Zasocitinib Clinical Trial Success: Takeda's Zasocitinib showed that about 70% of patients achieved significant skin clearance in Phase 3 trials, with plans to submit a New Drug Application in 2026, further solidifying its position in the dermatology market.
NASDAQ.COM
9.0
04-01NASDAQ.COM
MAIA Biotechnology Reports Significant Progress in THIO-101 Trial
  • Survival Milestone: In the THIO-101 trial, eight patients survived beyond two years after receiving Ateganosine followed by Cemiplimab, significantly exceeding standard survival expectations for late-stage non-small cell lung cancer patients, indicating the potential breakthrough nature of this therapy.
  • Remarkable Efficacy: One third-line patient achieved 33 months of survival, far surpassing the expected 5.8 months, while four second-line patients lived beyond 30 months, well above the documented 10.5-month survival typically seen with chemotherapy or checkpoint inhibitors alone, highlighting the treatment's effectiveness.
  • Trial Design Highlights: THIO-101 is a multicenter, open-label Phase 2 study primarily assessing safety and anti-tumor activity, currently expanding into Part C with plans to enroll 48 additional patients in Asia and Europe, demonstrating an acceptable safety profile in a heavily pre-treated population.
  • Broad Market Potential: MAIA aims to develop Ateganosine as a second-line or later treatment for non-small cell lung cancer patients, with the global immunotherapy market projected to exceed $50 billion, positioning Ateganosine as a potential entrant with a novel mechanism and differentiated clinical profile.
Newsfilter
2.0
03-31Newsfilter
MAIA Biotechnology Reports Breakthrough in Lung Cancer Treatment
  • Significant Survival Improvement: In the THIO-101 clinical trial, eight non-small cell lung cancer patients achieved overall survival beyond two years, with one patient in third-line therapy surviving 33 months, far exceeding the expected 5.8 months, indicating the potential breakthrough efficacy of this treatment.
  • Efficacy Validation: Among 24 patients in second-line therapy, survival exceeded 30 months compared to a standard treatment survival of only 10.5 months, suggesting that this treatment regimen could redefine existing standards of care for heavily pre-treated patients.
  • Clinical Trial Expansion: The THIO-101 trial is currently enrolling up to 48 participants in Asia and Europe, further validating the safety and efficacy of this therapy, which is expected to provide new treatment options for heavily pre-treated patients.
  • Innovative Mechanism: Ateganosine, as the first telomere-targeting agent, demonstrates unique advantages in treating non-small cell lung cancer by inducing specific immune responses and cancer cell death, potentially paving the way for new cancer treatment strategies.
Wall Street analysts forecast MAIA stock price to rise
1 Analyst Rating
Wall Street analysts forecast MAIA stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
14.00
Averages
14.00
High
14.00
Current: 0.000
sliders
Low
14.00
Averages
14.00
High
14.00
No data

No data

Valuation Metrics

The current forward P/E ratio for Maia Biotechnology Inc (MAIA.A) is 0.00, compared to its 5-year average forward P/E of -1.50. For a more detailed relative valuation and DCF analysis to assess Maia Biotechnology Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.50
Current PE
0.00
Overvalued PE
-0.58
Undervalued PE
-2.43

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.30
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.78
Undervalued EV/EBITDA
-1.83

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1.37
Current PS
1.22
Overvalued PS
4.48
Undervalued PS
-1.74

Financials

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Frequently Asked Questions

What is Maia Biotechnology Inc (MAIA) stock price today?

The current price of MAIA is 1.41 USD — it has increased 4.44

What is Maia Biotechnology Inc (MAIA)'s business?

MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer. The Company's THIO (6-thio-dG, 6-thio-2'-deoxyguanosine), is a lead asset, is an investigational dual mechanism of action drug candidate incorporating telomere targeting and immunogenicity. The modified nucleotide 6-thio-2-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in tumor regression in advanced, in vivo cancer models by induction of cancer type-specific immune memory. THIO is being developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors.

What is the price predicton of MAIA Stock?

Wall Street analysts forecast MAIA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MAIA is14.00 USD with a low forecast of 14.00 USD and a high forecast of 14.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Maia Biotechnology Inc (MAIA)'s revenue for the last quarter?

Maia Biotechnology Inc revenue for the last quarter amounts to -4.32M USD, decreased -13.25

What is Maia Biotechnology Inc (MAIA)'s earnings per share (EPS) for the last quarter?

Maia Biotechnology Inc. EPS for the last quarter amounts to USD, decreased

How many employees does Maia Biotechnology Inc (MAIA). have?

Maia Biotechnology Inc (MAIA) has 13 emplpoyees as of April 21 2026.

What is Maia Biotechnology Inc (MAIA) market cap?

Today MAIA has the market capitalization of 85.55M USD.