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CGEM Overview

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$
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0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
15.560
Open
14.800
VWAP
14.98
Vol
3.12M
Mkt Cap
923.71M
Low
14.340
Amount
46.69M
EV/EBITDA(TTM)
--
Total Shares
61.46M
EV
571.83M
EV/OCF(TTM)
--
P/S(TTM)
--
Cullinan Therapeutics, Inc. is a biopharmaceutical company. It has built a diversified portfolio of clinical-stage assets that inhibit key drivers of disease or harness the immune system to eliminate diseased cells in autoimmune diseases and cancer. Its portfolio includes a range of modalities. Its pipeline includes CLN-978, CLN-619, Zipalertinib (CLN-081/TAS6417), CLN-049, and CLN-617. CLN-978 is a CD19xCD3 T cell engager being developed for autoimmune diseases. CLN-619 is a monoclonal antibody that stabilizes expression of MICA/B on the tumor cell surface to promote tumor cell lysis mediated by cytotoxic innate and adaptive immune cells. Zipalertinib (CLN-081/TAS6417) is an orally available small-molecule, irreversible epidermal growth factor receptor inhibitor. CLN-049 is a FLT3xCD3 T cell engaging bispecific antibody. CLN-617 is a fusion protein combining two potent antitumor cytokines, interleukin-2 and interleukin-12 with tumor retention domains for the treatment of solid tumors.
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Events Timeline

(ET)
2026-05-19
08:10:00
Cullinan Therapeutics CLN-049 Receives FDA Orphan Drug Designation
select
2026-05-07 (ET)
2026-05-07
07:50:00
Cullinan Therapeutics Looks Forward to Initial Clinical Data for CLN-978 and Velinotamig
select
2026-05-04 (ET)
2026-05-04
10:30:00
Cullinan Therapeutics Shares Rise 7% to $14.40
select

News

Newsfilter
9.0
06-10Newsfilter
Cullinan Therapeutics Reports Promising Clinical Data for CLN-978 and Velinotamig
  • Significant Clinical Efficacy: CLN-978 demonstrated robust efficacy in the multi-dose RA clinical trial, achieving clinical remission in a poly-refractory patient with a rapid reduction in DAS28-ESR score from 4.0 to 2.2, highlighting its potential in treating refractory RA.
  • Favorable Safety Profile: Initial safety data from the multi-dose regimen in SLE patients were consistent with results from RA patients, with no severe adverse events observed, indicating good tolerability and laying a foundation for future clinical applications of CLN-978.
  • Remarkable Renal Responses: Velinotamig showed promising clinical activity in refractory SLE patients, with all subjects achieving complete renal responses after four intravenous doses, leading to significant reductions in SLEDAI-2K scores, underscoring its potential in autoimmune diseases.
  • Future Development Plans: Cullinan plans to report additional multi-dose data for CLN-978 in RA and SLE in Q3 and Q4 of 2026, respectively, and initiate a clinical trial for autoimmune cytopenias in early 2027, further expanding its clinical application scope.
NASDAQ.COM
8.5
06-09NASDAQ.COM
Cullinan Therapeutics to Host Immunology Day with Key Updates
  • Clinical Trial Progress: Cullinan Therapeutics is set to host an Immunology Day on June 10, 2026, where updates on CLN-978 and Velinotamig will be shared, likely attracting investor interest in its innovations within the autoimmune disease sector.
  • CLN-978 Studies: CLN-978, a CD19-targeting bispecific T cell engager, is undergoing three global phase 1 studies, with preliminary data indicating significant clinical benefits in systemic lupus erythematosus and rheumatoid arthritis patients, potentially driving further treatment development.
  • Velinotamig Development: The company licensed global rights to Velinotamig in 2025, currently conducting a phase 1 study for moderate to severe systemic lupus erythematosus, which may provide new treatment options for autoimmune diseases and expand its product pipeline.
  • Strong Financial Position: As of March 31, 2026, Cullinan reported $393 million in cash and investments, expected to fund operations through 2029, demonstrating a robust financial foundation for ongoing R&D and market expansion.
Newsfilter
9.0
06-06Newsfilter
CLN-978 Shows Significant Clinical Benefits in Autoimmune Diseases
  • Significant Clinical Benefits: CLN-978 demonstrated clinical benefits, including remissions in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating its potential as a treatment for multiple challenging autoimmune diseases.
  • B Cell Depletion Effects: The study revealed dose-dependent B cell depletion with CLN-978, with 82% of 14 SLE patients achieving over 80% reduction in B cell counts from baseline, providing strong evidence for its role as a disease-modifying treatment.
  • Favorable Safety Profile: CLN-978 was well tolerated across 10µg, 20µg, and 30µg dose cohorts, with most cytokine release syndrome (CRS) events being Grade 1, suggesting its potential for use in outpatient community care settings.
  • Multi-Dose Regimen Research: As multi-dose regimen studies progress, Cullinan plans to share initial data from the RA multi-dose cohort on June 10 during Immunology Day, further advancing the global clinical development of CLN-978.
NASDAQ.COM
9.0
05-19NASDAQ.COM
Cullinan Receives FDA Orphan Drug Designation
  • Orphan Drug Designation: Cullinan Therapeutics' CLN-049 has received Orphan Drug Designation from the FDA, providing development incentives such as tax credits and market exclusivity for its acute myeloid leukemia treatment.
  • Clinical Trial Incentives: This designation allows CLN-049 to benefit from tax credits for qualified clinical trials and exemptions from certain FDA user fees, thereby reducing R&D costs and accelerating the path to market.
  • Innovative Treatment Approach: CLN-049 is a novel FLT3xCD3 T cell engager designed to target FLT3-expressing leukemia cells, offering a new immunotherapeutic strategy for treating acute myeloid leukemia and myelodysplastic syndrome.
  • Positive Market Reaction: Following the designation, Cullinan's shares rose over 2% in pre-market trading, indicating a positive market sentiment regarding the drug's development prospects and reflecting investor confidence in the company's future growth potential.
Newsfilter
9.0
05-19Newsfilter
CLN-049 Receives FDA Orphan Drug Designation
  • FDA Orphan Drug Designation: CLN-049 has received Orphan Drug Designation from the FDA, highlighting the urgent need for therapies for relapsed/refractory acute myeloid leukemia (AML) patients, particularly those with TP53 mutations, indicating significant market potential.
  • Clinical Trial Progress: The ongoing Phase 1 clinical trial of CLN-049 demonstrates promising safety and tolerability, which is expected to provide new treatment options for AML patients, potentially improving survival rates and quality of life.
  • Market Exclusivity Advantage: With Orphan Drug Designation, CLN-049 will benefit from seven years of market exclusivity, presenting Cullinan Therapeutics with substantial commercial opportunities to establish a leading position in a competitive market.
  • Innovative Treatment Approach: As a novel FLT3xCD3 T cell engager, CLN-049 targets FLT3-expressing leukemia cells, offering a new immunotherapeutic strategy that could transform the treatment landscape for AML.
Newsfilter
9.0
05-18Newsfilter
Cullinan Therapeutics Presents Initial Clinical Data for CLN-978 at EULAR Congress
  • Clinical Data Presentation: Cullinan Therapeutics will present initial clinical data for CLN-978 at the EULAR Congress from June 3-6, 2026, showcasing findings from two Phase 1 studies focused on rheumatoid arthritis and systemic lupus erythematosus, indicating a favorable safety profile and early clinical activity signals.
  • Targeted Treatment Effects: Initial dose levels of CLN-978 demonstrate significant B cell depletion, with early clinical activity signals observed in patients with rheumatoid arthritis and systemic lupus erythematosus, potentially offering new hope for treating these refractory diseases.
  • Global Study Recruitment: The OUTRACE RA and OUTRACE SLE studies are actively recruiting patients globally, with the former targeting rheumatoid arthritis patients who have undergone multiple targeted treatments, and the latter focusing on systemic lupus erythematosus patients previously treated with biologics or immunosuppressants, reflecting the company's proactive clinical research strategy.
  • Innovative Drug Potential: CLN-978, as a novel bispecific T cell engager with high affinity and small molecular size, aims to provide a convenient subcutaneous administration option for patients with rheumatoid arthritis and systemic lupus erythematosus, potentially transforming existing treatment paradigms and enhancing patient quality of life.
Wall Street analysts forecast CGEM stock price to rise
10 Analyst Rating
Wall Street analysts forecast CGEM stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
24.00
Averages
31.50
High
38.00
Current: 0.000
sliders
Low
24.00
Averages
31.50
High
38.00
Clear Street
Buy
maintain
$33
AI Analysis
2026-05-19
Reason
Clear Street
Price Target
$33
AI Analysis
2026-05-19
maintain
Buy
Reason
Clear Street reiterated a Buy rating and $33 price target on Cullinan Therapeutics, saying the firm views the post-EULAR share pullback after release of the CLN-978 Phase 1 abstract as \"unwarranted,\" given an encouraging initial dataset. Safety to date appears manageable, and early clinical activity is likewise supportive, the analyst tells investors in a research note. The firm also noted that other bispecifics have required the highest, oncology-optimized doses to achieve comparable B-cll depletion.
Wedbush
Outperform
maintain
$36 -> $37
2026-05-08
Reason
Wedbush
Price Target
$36 -> $37
2026-05-08
maintain
Outperform
Reason
Wedbush raised the firm's price target on Cullinan Therapeutics to $37 from $36 and keeps an Outperform rating on the shares. The firm notes the company reported first quarter financials and provided corporate updates ahead of initial clinical data for CD19 TCE CLN-978 upcoming at the EULAR 2026 Congress. Given recent M&A activity surrounding BCMA-targeted TCEs, as well as an affinity profile for BCMA approximately two orders of magnitude higher than CD3, which has translated to a compelling efficacy and safety in multiple myeloma patients, Wedbush views the overall immunology portfolio for Cullinan as relatively undervalued.
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Valuation Metrics

The current forward P/E ratio for Cullinan Therapeutics Inc (CGEM.O) is 6.74, compared to its 5-year average forward P/E of -3.62. For a more detailed relative valuation and DCF analysis to assess Cullinan Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.62
Current PE
6.74
Overvalued PE
3.11
Undervalued PE
-10.34

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.85
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
8.07
Undervalued EV/EBITDA
-13.77

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
37.13
Current PS
22.87
Overvalued PS
92.24
Undervalued PS
-17.97

Financials

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Whales Holding CGEM

B
BVF Partners L.P.
Holding
CGEM
+14.24%
3M Return
V
VR Management, LLC
Holding
CGEM
+10.22%
3M Return
A
Artal Group S.A.
Holding
CGEM
+9.19%
3M Return
A
Affinity Asset Advisors, LLC
Holding
CGEM
+6.76%
3M Return
K
Kynam Capital Management, LP
Holding
CGEM
-1.95%
3M Return

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Frequently Asked Questions

What is Cullinan Therapeutics Inc (CGEM) stock price today?

The current price of CGEM is 15.03 USD — it has increased 4.09

What is Cullinan Therapeutics Inc (CGEM)'s business?

Cullinan Therapeutics, Inc. is a biopharmaceutical company. It has built a diversified portfolio of clinical-stage assets that inhibit key drivers of disease or harness the immune system to eliminate diseased cells in autoimmune diseases and cancer. Its portfolio includes a range of modalities. Its pipeline includes CLN-978, CLN-619, Zipalertinib (CLN-081/TAS6417), CLN-049, and CLN-617. CLN-978 is a CD19xCD3 T cell engager being developed for autoimmune diseases. CLN-619 is a monoclonal antibody that stabilizes expression of MICA/B on the tumor cell surface to promote tumor cell lysis mediated by cytotoxic innate and adaptive immune cells. Zipalertinib (CLN-081/TAS6417) is an orally available small-molecule, irreversible epidermal growth factor receptor inhibitor. CLN-049 is a FLT3xCD3 T cell engaging bispecific antibody. CLN-617 is a fusion protein combining two potent antitumor cytokines, interleukin-2 and interleukin-12 with tumor retention domains for the treatment of solid tumors.

What is the price predicton of CGEM Stock?

Wall Street analysts forecast CGEM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CGEM is31.50 USD with a low forecast of 24.00 USD and a high forecast of 38.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cullinan Therapeutics Inc (CGEM)'s revenue for the last quarter?

Cullinan Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Cullinan Therapeutics Inc (CGEM)'s earnings per share (EPS) for the last quarter?

Cullinan Therapeutics Inc. EPS for the last quarter amounts to -0.82 USD, decreased -0.00

How many employees does Cullinan Therapeutics Inc (CGEM). have?

Cullinan Therapeutics Inc (CGEM) has 109 emplpoyees as of June 20 2026.

What is Cullinan Therapeutics Inc (CGEM) market cap?

Today CGEM has the market capitalization of 923.71M USD.