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GYRE Overview

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ET
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0.000
0.000(0.000%)
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ET
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Intellectia

Loading chart...

High
8.120
Open
8.120
VWAP
8.12
Vol
7.05K
Mkt Cap
738.03M
Low
8.120
Amount
57.25K
EV/EBITDA(TTM)
49.79
Total Shares
90.89M
EV
712.91M
EV/OCF(TTM)
183.88
P/S(TTM)
7.47
Gyre Therapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of F351 (Hydronidone) for the treatment of MASH-associated fibrosis in the United States. It is also advancing a diverse pipeline in the PRC through its indirect controlling interest in Gyre Pharmaceuticals, including ETUARY therapeutic expansions, F573, F528, and F230. F351 is a structural derivative of ETUARY. F573 is its clinical-stage product candidate for the treatment of acute/acute-on-chronic liver failure (ALF/ACLF) in Phase 2 clinical trials in the PRC. F528 is a preclinical-stage candidate targeting chronic obstructive pulmonary disease. F230 is a clinical-stage compound for the treatment of pulmonary arterial hypertension. It is focused on commercializing therapies for the treatment of pulmonary fibrosis through its two therapeutic products: ETUARY (pirfenidone) and nintedanib. It is also focused on commercializing the avatrombopag product.
Show More

Events Timeline

(ET)
2026-03-02
08:30:00
Gyre Therapeutics Acquires Cullgen for $300M
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2026-01-05 (ET)
2026-01-05
07:20:00
Gyre Therapeutics Communicates Hydronidone Application with China's Drug Administration
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2025-11-07 (ET)
2025-11-07
06:16:22
Gyre Therapeutics lowers FY25 revenue forecast to $115M-$118M from previous estimate of $118M-$128M.
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2025-11-07
06:14:59
Gyre Therapeutics Announces Q3 Earnings Per Share of 3 Cents, Exceeding Consensus Estimate of 2 Cents
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2025-10-15 (ET)
2025-10-15
07:03:50
Gyre Therapeutics finishes enrolling participants for Phase 3 trial of Pirfenidone capsules.
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2025-08-22 (ET)
2025-08-22
07:02:16
Dan Weng Joins the Board of Directors at Gyre Therapeutics
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2025-08-11 (ET)
2025-08-11
16:03:58
Gyre Therapeutics CEO Han Ying steps down
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2025-06-10 (ET)
2025-06-10
07:08:05
Gyre Therapeutics announces first doing in Phase 1 trial of F230
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News

stocktwits
8.5
03-02stocktwits
Gyre Therapeutics Acquires Cullgen in $300 Million All-Stock Deal
  • Acquisition Details: Gyre Therapeutics announced its acquisition of Cullgen in an all-stock transaction valued at approximately $300 million, with Cullgen set to become a wholly owned subsidiary, and the deal expected to close in early Q2 2026 pending U.S. regulatory approvals.
  • Market Reaction: Following the announcement, GYRE's shares rose by 8%, indicating a positive market response to the acquisition, although the stock has lost 22% over the past 12 months, reflecting cautious optimism among investors regarding future growth prospects.
  • Challenges for Pulmatrix: Pulmatrix's stock plummeted 36% after the termination of its merger agreement with Cullgen, and the company is now actively seeking alternative merger opportunities, highlighting the uncertainty and pressure faced in the industry consolidation landscape.
  • Regulatory Hurdles: Pulmatrix noted that it did not receive the necessary approval from the China Securities Regulatory Commission, which led to the termination of the deal with Cullgen, underscoring the complexities and potential risks associated with cross-border transactions.
Benzinga
9.5
01-05Benzinga
Altimmune Inc Receives FDA Breakthrough Therapy Designation for Pemvidutide, Shares Surge 23.6%
  • FDA Certification Impact: Altimmune Inc's Pemvidutide received FDA Breakthrough Therapy Designation, leading to a 23.6% surge in shares to $4.34 on Monday, indicating strong market confidence in its potential efficacy and possibly accelerating its path to market.
  • Clinical Progress: GH Research PLC's GH001 lifted from FDA clinical hold saw shares rise 33.8% to $17.72, reflecting significant advancements in drug development that are expected to enhance its competitive position in the market.
  • Executive Change: Rayonier Advanced Materials Inc appointed Scott M. Sutton as the new CEO, resulting in a 14.1% increase in shares to $6.68, suggesting that this leadership change could bring new strategic directions and growth opportunities for the company.
  • Market Rebound: The overall market showed strong performance with the S&P 500 index rising, reflecting investor optimism about economic recovery, which may drive more capital inflows into the stock market.
Globenewswire
9.0
01-05Globenewswire
Gyre Pharmaceuticals Reaches Pre-NDA Consensus with China's CDE for Hydronidone Approval
  • Clear Regulatory Pathway: Gyre Pharmaceuticals has reached consensus with China's CDE that existing Phase 3 clinical data supports a conditional approval filing for Hydronidone, with plans to submit an NDA in the first half of 2026, marking a significant advancement in the anti-fibrotic treatment landscape.
  • Clinical Data Validation: In the Phase 3 trial, Hydronidone demonstrated that 52.85% of patients achieved ≥1-stage fibrosis regression at Week 52, significantly outperforming the placebo group's 29.84% (p=0.0002), establishing a strong foundation for its market potential.
  • Priority Review Eligibility: The CDE confirmed that Hydronidone meets the criteria for inclusion in China's Priority Review Program for Innovative Drugs, which is expected to expedite the approval process, enabling the company to quickly capture market share and address urgent patient needs.
  • Follow-up Clinical Trial Plans: The company plans to conduct an additional confirmatory clinical trial (Phase 3c) to support the transition from conditional approval to full approval, further solidifying its position in the Chinese market.
Yahoo Finance
9.0
01-05Yahoo Finance
Gyre Pharmaceuticals Reaches Pre-NDA Consensus with China's CDE for Hydronidone Approval
  • Clinical Data Support: Gyre Pharmaceuticals reached consensus with China's CDE that existing Phase 3 clinical data supports a conditional approval filing for Hydronidone, expected to be submitted in the first half of 2026, marking a significant advancement in the anti-fibrotic treatment space.
  • Priority Review Eligibility: Hydronidone meets the criteria for inclusion in China's Priority Review and Approval Program for Innovative Drugs, which is expected to expedite the approval process and address the urgent market need for anti-fibrotic therapies in China, presenting substantial market potential.
  • Significant Market Demand: Approximately 2.6 million patients in China are eligible for anti-fibrotic intervention, and the launch of Hydronidone will fill this critical medical gap, likely enhancing Gyre's market share and revenue significantly.
  • Follow-up Clinical Trial Plans: The company plans to conduct an additional Phase 3c confirmatory clinical trial to support the transition from conditional approval to regular approval, further solidifying Hydronidone's position in the market.
NASDAQ.COM
9.5
2025-11-07NASDAQ.COM
GYRE THERAPEUTICS, INC. Reports Increase in Q3 Earnings
  • Earnings Growth: GYRE THERAPEUTICS, INC. reported a profit of $3.61 million for Q3, up from $1.12 million in the same period last year.

  • Earnings Per Share: The company's earnings per share (EPS) increased to $0.03, compared to $0.01 in the previous year.

  • Revenue Increase: Revenue for the quarter rose by 19.9% to $30.56 million, up from $25.49 million last year.

  • Financial Summary: Key financial figures include earnings of $3.61 million, EPS of $0.03, and revenue of $30.56 million, reflecting significant growth year-over-year.

NASDAQ.COM
6.0
2025-10-17NASDAQ.COM
Fresh Strong Sell Stocks for October 17th
  • Stocks Added to Zacks Rank #5: Gyre Therapeutics, Darling Ingredients, and Cresco Labs have been added to the Zacks Rank #5 (Strong Sell) List due to significant downward revisions in their earnings estimates over the past 60 days.

  • Investment Opportunities: Despite their current rankings, these stocks were selected by Zacks experts as potential high-growth investments, with previous recommendations achieving substantial gains.

Wall Street analysts forecast GYRE stock price to rise
2 Analyst Rating
Wall Street analysts forecast GYRE stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
18.00
Averages
19.00
High
20.00
Current: 0.000
sliders
Low
18.00
Averages
19.00
High
20.00
H.C. Wainwright
H.C. Wainwright
initiated
$18
AI Analysis
2025-08-26
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$18
AI Analysis
2025-08-26
initiated
Reason
H.C. Wainwright initiated coverage of Gyre Therapeutics with a Buy rating and $18 price target. The company's lead asset hydronidone is a structural analog of the anti-fibrotic drug pirfenidone and a "potent inhibitor" of fibrosis, the analyst tells investors in a research note. The firm believes Gyre is "still flying under the radar with investors" despite a "compelling" portfolio of established therapeutics.

Valuation Metrics

The current forward P/E ratio for Gyre Therapeutics Inc (GYRE.O) is 31.67, compared to its 5-year average forward P/E of 11.97. For a more detailed relative valuation and DCF analysis to assess Gyre Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
11.97
Current PE
31.67
Overvalued PE
33.91
Undervalued PE
-9.97

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
9.33
Current EV/EBITDA
34.53
Overvalued EV/EBITDA
27.36
Undervalued EV/EBITDA
-8.71

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1.43
Current PS
4.17
Overvalued PS
3.78
Undervalued PS
-0.93

Financials

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Gyre Therapeutics Inc
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Frequently Asked Questions

What is Gyre Therapeutics Inc (GYRE) stock price today?

The current price of GYRE is 8.12 USD — it has increased 0

What is Gyre Therapeutics Inc (GYRE)'s business?

Gyre Therapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of F351 (Hydronidone) for the treatment of MASH-associated fibrosis in the United States. It is also advancing a diverse pipeline in the PRC through its indirect controlling interest in Gyre Pharmaceuticals, including ETUARY therapeutic expansions, F573, F528, and F230. F351 is a structural derivative of ETUARY. F573 is its clinical-stage product candidate for the treatment of acute/acute-on-chronic liver failure (ALF/ACLF) in Phase 2 clinical trials in the PRC. F528 is a preclinical-stage candidate targeting chronic obstructive pulmonary disease. F230 is a clinical-stage compound for the treatment of pulmonary arterial hypertension. It is focused on commercializing therapies for the treatment of pulmonary fibrosis through its two therapeutic products: ETUARY (pirfenidone) and nintedanib. It is also focused on commercializing the avatrombopag product.

What is the price predicton of GYRE Stock?

Wall Street analysts forecast GYRE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GYRE is19.00 USD with a low forecast of 18.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Gyre Therapeutics Inc (GYRE)'s revenue for the last quarter?

Gyre Therapeutics Inc revenue for the last quarter amounts to 30.56M USD, increased 19.92

What is Gyre Therapeutics Inc (GYRE)'s earnings per share (EPS) for the last quarter?

Gyre Therapeutics Inc. EPS for the last quarter amounts to 0.03 USD, increased 200.00

How many employees does Gyre Therapeutics Inc (GYRE). have?

Gyre Therapeutics Inc (GYRE) has 574 emplpoyees as of March 11 2026.

What is Gyre Therapeutics Inc (GYRE) market cap?

Today GYRE has the market capitalization of 738.03M USD.