Analyst Recognizes Potential in Neumora's Growing Obesity and Metabolic Portfolio
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 01 2025
0mins
Should l Buy NMRA?
Source: Benzinga
RBC Capital Markets Upgrade: Neumora Therapeutics, Inc. has been upgraded from Sector Perform to Outperform by RBC Capital Markets, with a price target increase from $4 to $7, reflecting the company's potential beyond neurology.
Pipeline Developments: Neumora is advancing its NMRA-215 obesity treatment, showing promising preclinical results, and plans to initiate a clinical program in early 2026, alongside ongoing studies for its M4 franchise targeting neuropsychiatric disorders.
Financial Outlook: The company has $171.5 million in cash and equivalents, which is expected to sustain operations through 2027, indicating a solid financial position for upcoming developments.
Market Potential: Analysts highlight the NLRP3 target as a significant opportunity in metabolic and obesity treatments, with Neumora positioned to capitalize on this emerging market, despite some caution regarding its later-stage neuro programs.
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Analyst Views on NMRA
Wall Street analysts forecast NMRA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NMRA is 9.33 USD with a low forecast of 3.00 USD and a high forecast of 18.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
8 Analyst Rating
5 Buy
2 Hold
1 Sell
Moderate Buy
Current: 2.020
Low
3.00
Averages
9.33
High
18.00
Current: 2.020
Low
3.00
Averages
9.33
High
18.00
About NMRA
Neumora Therapeutics Inc. is a clinical-stage biopharmaceutical company. The Company's therapeutic pipeline consists of seven clinical and preclinical neuroscience programs that target novel mechanisms of action for a broad range of underserved neuropsychiatric disorders and neurodegenerative diseases. Its advanced product candidate, navacaprant (NMRA-140), is a novel once-daily oral kappa opioid receptor (KOR) antagonist that is being developed for the treatment of depressive disorder (MDD). Navacaprant is being investigated in the KOASTAL pivotal Phase 3 program, evaluating navacaprant monotherapy in patients with moderate to severe MDD. The Company's next advanced product candidate is NMRA-511, which is a highly selective, novel antagonist of the vasopressin 1a receptor (V1aR) being developed for the treatment of agitation associated with dementia due to Alzheimer's disease (AD).
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Clinical Trial Progress: The approval supports the company's competitiveness in the global market, as Glatiramer Acetate remains a key product despite revenue erosion from generics, highlighting its ongoing relevance in the biotech sector.
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- Favorable Safety Profile: NMRA-511 demonstrated good tolerability and safety, with treatment-emergent adverse events (TEAEs) typically mild to moderate, and a low discontinuation rate of only 2.5% due to TEAEs, establishing a solid foundation for future clinical applications.
- Clear Next Steps: Neumora plans to launch a multiple ascending dose extension study at higher doses in 2026, develop an extended-release formulation for once-daily dosing, and initiate a Phase 2/3 dose-ranging study, reflecting strong confidence in NMRA-511's long-term development.
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- Rising Investor Interest: Despite no new updates, Neumora Therapeutics and BioRestorative Therapies saw increases of 16.02% and 6.90% respectively, indicating broad investor interest and optimism in the biotech sector, which may fuel a wave of investment across the industry.
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