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GLUE Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
16.642
Open
16.040
VWAP
16.34
Vol
1.65M
Mkt Cap
1.24B
Low
15.935
Amount
26.93M
EV/EBITDA(TTM)
--
Total Shares
80.02M
EV
865.54M
EV/OCF(TTM)
--
P/S(TTM)
10.46
Monte Rosa Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is engaged in developing a portfolio of novel and molecular glue degraders (MGDs). MGDs are small molecule drugs that employ the body’s natural protein destruction mechanisms to selectively degrade therapeutically relevant proteins. It has developed a proprietary and industry leading discovery engine, called Quantitative and Engineered Elimination of Neosubstrates (QuEEN) to enable its target centric MGD discovery and development approach and its rational design of MGD product candidates. Its product candidate, MRT-2359, is an orally bioavailable MGD targeting the translation termination factor protein GSPT1. MRT-2359 is in clinical development for potential use in MYC-driven tumors, including metastatic non-small cell lung cancer, small cell lung cancer, and neuroendocrine tumors. Its other product candidates include MRT-6160 and MRT-8102.
Show More

Events Timeline

(ET)
2026-03-17
11:10:00
Monte Rosa Reports Q4 Net Loss of $46.1M
select
2026-03-17
07:10:00
Monte Rosa Expects Cash to Fund Operations Through 2029
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2026-03-16 (ET)
2026-03-16
07:10:00
Monte Rosa Enters Supply Agreement with Johnson & Johnson to Evaluate MRT-2359
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2026-02-24 (ET)
2026-02-24
07:40:00
Monte Rosa Updates Clinical Data for MRT-2359
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2026-02-11 (ET)
2026-02-11
16:40:00
Monte Rosa Therapeutics Files Automatic Mixed Securities Shelf
select
2026-01-09 (ET)
2026-01-09
06:20:00
Deal Size Increased to $300M in Common Stock
select
2026-01-07 (ET)
2026-01-07
16:20:00
Major Averages Close Mixed as Investors Take Profits
select
2026-01-07
16:10:00
Monte Rosa Therapeutics Launches $200M Public Offering
select

News

seekingalpha
9.5
03-17seekingalpha
Monte Rosa Therapeutics Reports Q4 Loss and Revenue Decline
  • Widening Net Loss: Monte Rosa Therapeutics reported a net loss of $46.1 million in Q4 2025, significantly up from $13.4 million in Q4 2024, indicating challenges in financial management and cost control.
  • Revenue Plummets: The company's revenue for the fourth quarter was $2.78 million, a staggering 95.4% year-over-year decline, missing expectations by $12.73 million, reflecting weak market demand and poor product sales performance.
  • Collaboration Revenue Decline: Collaboration revenue for Q4 2025 was $2.8 million, down from $60.6 million in Q4 2024, with total collaboration revenue for the year at $123.7 million, up from $75.6 million in 2024, yet indicating diminishing returns from partnerships with Roche and Novartis.
  • Market Reaction: Although the collaboration with Johnson & Johnson for cancer therapy trials has garnered some market interest, the ongoing deterioration in financial performance may negatively impact investor confidence, limiting further stock price appreciation.
NASDAQ.COM
9.5
03-17NASDAQ.COM
Agenus Surpasses Earnings and Revenue Expectations
  • Earnings Beat: Agenus reported earnings of $0.56 per share, significantly exceeding the Zacks consensus estimate of a loss of $1.27 per share, and improving from a loss of $2.04 per share a year ago, indicating a strong recovery in profitability that is likely to boost investor confidence.
  • Significant Revenue Growth: The company posted revenues of $34.2 million for the quarter, surpassing the Zacks consensus estimate of $29.3 million and reflecting a 27.5% increase from $26.84 million a year ago, demonstrating sustained market demand in the biopharmaceutical sector.
  • Cautious Future Outlook: Although Agenus has surpassed consensus EPS estimates twice in the past four quarters, management's commentary on future earnings expectations will be crucial for stock price movements; currently, the Zacks Rank is 3 (Hold), suggesting performance may align with the market in the near term.
  • Industry Ranking Impact: The Medical - Biomedical and Genetics industry, where Agenus operates, is currently ranked in the bottom 42% by Zacks, which could negatively affect the company's stock performance, prompting investors to monitor overall industry trends for potential impacts on future performance.
NASDAQ.COM
7.5
03-16NASDAQ.COM
Monte Rosa Enters Supply Agreement with Johnson & Johnson for MRT-2359
  • Clinical Trial Collaboration: Monte Rosa Therapeutics has signed a supply agreement with Johnson & Johnson to evaluate MRT-2359 in combination with ERLEADA for the treatment of metastatic castration-resistant prostate cancer, with a new Phase 2 study expected to start in Q3 2026, indicating the company's strategic positioning in prostate cancer treatment.
  • Drug Combination Research: MRT-2359, an orally bioavailable molecular glue degrader, will be studied in 25 AR-mutant patients to assess its efficacy and safety alongside ERLEADA, with potential expansion to other patient subsets if results are positive, reflecting the company's confidence in new therapeutic options.
  • Financial Performance: As of September 30, 2025, Monte Rosa reported collaboration revenue of $12.8 million, a 39% increase from $9.2 million in the prior year, despite a net loss widening to $27.1 million, showcasing the company's ongoing investment in R&D and market expansion.
  • Stock Performance: Following this announcement, GLUE's stock rose 4.74% to $16.78, reflecting market optimism regarding its collaboration with Johnson & Johnson, with the stock trading between $3.50 and $25.77 over the past year, indicating investor interest in its future potential.
seekingalpha
7.5
03-16seekingalpha
Monte Rosa Enters Supply Agreement with Johnson & Johnson for Cancer Treatment
  • Supply Agreement Established: Monte Rosa Therapeutics (GLUE) has signed a supply agreement with Johnson & Johnson (JNJ) to evaluate MRT-2359 in combination with apalutamide for treating metastatic castration-resistant prostate cancer (mCRPC) patients, marking a strategic collaboration in cancer treatment.
  • Clinical Trial Plans: Under the agreement, Monte Rosa will conduct and sponsor the trial, planning to initiate a signal-confirming phase 2 study targeting AR mutant patients in Q3 2026, with an expected enrollment of up to 25 patients to efficiently assess the efficacy and safety of MRT-2359 plus ERLEADA.
  • Positive Market Reaction: Following the announcement, Monte Rosa's shares rose by 1.6% to $16.28, reflecting market optimism regarding the new research direction and potentially boosting investor confidence.
  • Research Evaluation Metrics: The study will evaluate key metrics including PSA response, RECIST response, duration of response, progression-free survival (PFS), and safety, with the potential to expand to other patient subsets if activity in the AR mutant population is confirmed.
Barron's
5.0
01-17Barron's
Activist Investors Target Staar Surgical, Alumis, and Other Stocks
  • Increased Investments: There has been a notable rise in holdings across various sectors, indicating a growing confidence among investors.

  • Market Trends: The increase in holdings reflects broader market trends, suggesting potential growth opportunities in the near future.

NASDAQ.COM
9.0
01-09NASDAQ.COM
ScinoPharm Secures FDA Approval for Glatiramer Acetate Injection in Multiple Sclerosis
  • FDA Approval: ScinoPharm Taiwan (TWSE:1789) received FDA approval for its Glatiramer Acetate Injection for treating adult multiple sclerosis patients, marking the company's first finished drug approval and paving the way for regulatory submissions in Europe and Asia for broader commercialization.
  • Market Reaction: Following this announcement, ScinoPharm's stock price rose by 3.08% to NT$23.40 on January 8, 2025, reflecting positive market sentiment regarding the product's prospects.
  • Clinical Trial Progress: The approval supports the company's competitiveness in the global market, as Glatiramer Acetate remains a key product despite revenue erosion from generics, highlighting its ongoing relevance in the biotech sector.
  • Strategic Positioning: This approval not only strengthens ScinoPharm's position in the biopharmaceutical landscape but also lays the groundwork for future market expansions, demonstrating the company's commitment to innovative drug development.
Wall Street analysts forecast GLUE stock price to rise
8 Analyst Rating
Wall Street analysts forecast GLUE stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
30.40
High
37.00
Current: 0.000
sliders
Low
20.00
Averages
30.40
High
37.00
Guggenheim
Buy
downgrade
$34 -> $30
AI Analysis
2026-03-18
Reason
Guggenheim
Price Target
$34 -> $30
AI Analysis
2026-03-18
downgrade
Buy
Reason
Guggenheim lowered the firm's price target on Monte Rosa Therapeutics to $30 from $34 and keeps a Buy rating on the shares. The firm, which is updating its model to reflect Q4 results, notes that its price target moves down as a result of stock dilution.
Wells Fargo
Equal Weight -> Overweight
upgrade
$22
2025-12-16
Reason
Wells Fargo
Price Target
$22
2025-12-16
upgrade
Equal Weight -> Overweight
Reason
Wells Fargo upgraded Monte Rosa Therapeutics (GLUE) to Overweight from Equal Weight with a $22 price target. The firm cites the company's catalyst path in 2026 for the upgrade. Wells sees upside from MRT-8102's Phase 1 update in the first half of 2026 and likely disclosure of Novartis' (NVS) plans for MRT-6160. The MRT-8102 Phase 1 update should be "de-risking," the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for GLUE
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Valuation Metrics

The current forward P/E ratio for Monte Rosa Therapeutics Inc (GLUE.O) is -8.89, compared to its 5-year average forward P/E of -4.79. For a more detailed relative valuation and DCF analysis to assess Monte Rosa Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.79
Current PE
-8.89
Overvalued PE
-1.29
Undervalued PE
-8.30

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.21
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.52
Undervalued EV/EBITDA
-5.94

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
10.31
Current PS
29.49
Overvalued PS
23.36
Undervalued PS
-2.74

Financials

AI Analysis
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Quarterly

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Whales Holding GLUE

N
New Enterprise Associates, Inc.
Holding
GLUE
+1.62%
3M Return
V
Vestal Point Capital, LP
Holding
GLUE
+1.52%
3M Return
T
TCG Crossover Management, LLC
Holding
GLUE
-2.27%
3M Return
B
BVF Partners L.P.
Holding
GLUE
-2.32%
3M Return
B
Baker Bros. Advisors LP
Holding
GLUE
-4.07%
3M Return
S
Suvretta Capital Management, LLC
Holding
GLUE
-12.21%
3M Return

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Frequently Asked Questions

What is Monte Rosa Therapeutics Inc (GLUE) stock price today?

The current price of GLUE is 16.45 USD — it has increased 5.92

What is Monte Rosa Therapeutics Inc (GLUE)'s business?

Monte Rosa Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is engaged in developing a portfolio of novel and molecular glue degraders (MGDs). MGDs are small molecule drugs that employ the body’s natural protein destruction mechanisms to selectively degrade therapeutically relevant proteins. It has developed a proprietary and industry leading discovery engine, called Quantitative and Engineered Elimination of Neosubstrates (QuEEN) to enable its target centric MGD discovery and development approach and its rational design of MGD product candidates. Its product candidate, MRT-2359, is an orally bioavailable MGD targeting the translation termination factor protein GSPT1. MRT-2359 is in clinical development for potential use in MYC-driven tumors, including metastatic non-small cell lung cancer, small cell lung cancer, and neuroendocrine tumors. Its other product candidates include MRT-6160 and MRT-8102.

What is the price predicton of GLUE Stock?

Wall Street analysts forecast GLUE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GLUE is30.40 USD with a low forecast of 20.00 USD and a high forecast of 37.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Monte Rosa Therapeutics Inc (GLUE)'s revenue for the last quarter?

Monte Rosa Therapeutics Inc revenue for the last quarter amounts to 2.78M USD, decreased -95.41

What is Monte Rosa Therapeutics Inc (GLUE)'s earnings per share (EPS) for the last quarter?

Monte Rosa Therapeutics Inc. EPS for the last quarter amounts to -0.54 USD, decreased -437.50

How many employees does Monte Rosa Therapeutics Inc (GLUE). have?

Monte Rosa Therapeutics Inc (GLUE) has 150 emplpoyees as of April 01 2026.

What is Monte Rosa Therapeutics Inc (GLUE) market cap?

Today GLUE has the market capitalization of 1.24B USD.