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SNDX Overview

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ET
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ET
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Intellectia

Loading chart...

High
19.880
Open
19.750
VWAP
19.63
Vol
862.05K
Mkt Cap
1.74B
Low
19.430
Amount
16.93M
EV/EBITDA(TTM)
--
Total Shares
88.61M
EV
1.73B
EV/OCF(TTM)
--
P/S(TTM)
7.91
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Show More

Events Timeline

(ET)
2026-04-30
16:30:00
Company Reports Q1 Revenue of $64.86M, Below Expectations
select

News

Newsfilter
9.0
05-21Newsfilter
Syndax's Revuforj Showcases New Data at ASCO Meeting
  • Clinical Trial Results: At the upcoming ASCO Annual Meeting, Syndax will present clinical data from 21 acute leukemia patients treated with Revuforj, demonstrating favorable overall survival and relapse rates, which could enhance the drug's acceptance in post-transplant maintenance therapy.
  • Pharmacokinetic Features: The pharmacokinetic data of Revuforj will be highlighted, emphasizing its unique ability to be administered with commonly prescribed gastric acid reducers without compromising efficacy, which may improve patient adherence and strengthen market competitiveness.
  • New Trial Designs: Syndax will showcase key trial designs for Revuforj in combination with varying intensities of chemotherapy, particularly for newly diagnosed patients with NPM1 mutations or KMT2A rearrangements, providing crucial evidence for future treatment protocols that could redefine standard care.
  • Scientific Leadership: Syndax's strong presence at ASCO not only underscores its scientific leadership in menin inhibition but also reflects its deep commitment to advancing cancer care, likely attracting increased investor interest in its research pipeline.
Newsfilter
8.5
05-12Newsfilter
Revumenib Shows Promising Results in Acute Leukemia Treatment
  • Clinical Data Highlights: Syndax Pharmaceuticals presented 12 abstracts on Revuforj (revumenib) at the EHA 2026 Congress, demonstrating strong clinical activity across acute leukemia subtypes, particularly KMT2Ar, NPM1m, and NUP98r, potentially transforming treatment paradigms.
  • Efficacy and Tolerability: New real-world data show that revumenib, both as monotherapy and in combination, exhibits favorable tolerability and significant efficacy in acute leukemia patients, particularly in the post-transplant setting, supporting physician decision-making and enhancing confidence in ongoing clinical trials.
  • Frontline and Relapse Data: The combination of revumenib with intensive chemotherapy shows up to 50% MRD negativity rates and significantly improved transplant success rates in newly diagnosed acute myeloid leukemia patients, indicating its potential in clinical applications.
  • Scientific Leadership: Nick Botwood, Chief Medical Officer of Syndax, stated that these data underscore the company's scientific leadership in menin inhibition, with expectations to provide new treatment options for over 50% of acute myeloid leukemia patients.
seekingalpha
9.5
05-01seekingalpha
Syndax Pharmaceuticals Q1 2026 Earnings Call Highlights
  • Strong Sales Performance: Syndax Pharmaceuticals achieved over $100 million in combined sales of Revuforj and Niktimvo in Q1 2026, demonstrating robust demand for both medicines and advancing the company towards profitability.
  • Revuforj Revenue Growth: Revuforj net revenue reached $49 million, significantly increasing the estimate of KMT2A patients able to receive potentially curative stem cell transplants to nearly 50%, up from the previous estimate of 33%, indicating improved treatment efficacy.
  • Stable Niktimvo Performance: Niktimvo delivered $55 million in net revenue in Q1, reflecting consistent new patient starts despite natural attrition, suggesting strong ongoing market demand.
  • Sufficient Funding: As of March 31, 2026, the company reported $352.1 million in cash, cash equivalents, and marketable securities, ensuring the ability to continue investing in its R&D and commercial priorities.
seekingalpha
9.5
04-30seekingalpha
Syndax Pharmaceuticals Q1 Earnings Beat Expectations
  • Earnings Highlights: Syndax Pharmaceuticals reported a Q1 GAAP EPS of -$0.48, beating expectations by $0.13, indicating an improving trend in the company's profitability.
  • Revenue Surge: The company achieved revenue of $64.9 million in Q1, representing a remarkable year-over-year growth of 223.9%, although it fell short of expectations, reflecting strong market demand for its products.
  • Expense Forecast: For the full year 2026, total research and development plus selling, general, and administrative expenses are expected to be approximately $400 million, excluding an estimated $50 million in non-cash stock compensation, highlighting the company's ongoing investment in business expansion.
  • Market Outlook: Despite missing revenue expectations, Syndax's robust growth momentum and upcoming drug launches may attract investor interest and enhance market confidence.
Newsfilter
9.5
04-24Newsfilter
Syndax Pharmaceuticals to Report Q1 2026 Financial Results
  • Earnings Release Schedule: Syndax Pharmaceuticals is set to announce its Q1 2026 financial results on April 30, 2026, which is expected to significantly impact investor sentiment.
  • Conference Call Details: Management will host a conference call and live audio webcast at 4:30 p.m. ET on the same day, providing investors with direct access to company updates and enhancing transparency.
  • Replay Availability: For those unable to attend the live session, a replay will be accessible approximately 24 hours post-call and will remain available for 90 days, ensuring widespread dissemination of critical information.
  • Pipeline Highlights: Syndax's pipeline features FDA-approved cancer therapies like Revuforj® and Niktimvo™, showcasing the company's ongoing commitment and potential in cancer treatment, which may attract increased investor interest.
Fool
6.5
03-22Fool
DAFNA Capital Reduces Stake in Syndax Pharmaceuticals
  • Share Reduction Details: DAFNA Capital reported in its February 17, 2026 SEC filing that it sold 222,847 shares of Syndax Pharmaceuticals in Q4, with an estimated transaction value of $3.89 million, reflecting a cautious outlook on the company's future performance.
  • Ownership Percentage Change: Following the sale, DAFNA's stake in Syndax decreased to 1.36% from 1.90% in the previous quarter, indicating a strategic adjustment in its investment portfolio.
  • Market Performance Comparison: As of last Friday, Syndax's stock price stood at $24.23, marking a 72% increase over the past year, significantly outperforming the S&P 500's 15% rise during the same period, highlighting its strong position in the biopharmaceutical sector.
  • Company Growth Prospects: Syndax focuses on developing oncology therapies, and despite facing high operating costs and ongoing losses, its $172 million in 2025 sales and rapidly scaling commercial products demonstrate its potential in transitioning from clinical to commercial-stage biotech.
Wall Street analysts forecast SNDX stock price to rise
10 Analyst Rating
Wall Street analysts forecast SNDX stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
UBS
Buy
maintain
$38 -> $37
AI Analysis
2026-05-13
Reason
UBS
Price Target
$38 -> $37
AI Analysis
2026-05-13
maintain
Buy
Reason
UBS lowered the firm's price target on Syndax to $37 from $38 and keeps a Buy rating on the shares.
Stifel
Buy
maintain
$45 -> $46
2026-05-04
Reason
Stifel
Price Target
$45 -> $46
2026-05-04
maintain
Buy
Reason
Stifel raised the firm's price target on Syndax to $46 from $45 and keeps a Buy rating on the shares. Despite modest consensus misses on Revuforj and Niktimvo sales weighing on shares, the firm is "incrementally" more positive and confident in the trajectory of the Revuforj, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SNDX
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Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX.O) is 0.00, compared to its 5-year average forward P/E of -6.62. For a more detailed relative valuation and DCF analysis to assess Syndax Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.62
Current PE
0.00
Overvalued PE
-4.22
Undervalued PE
-9.03

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.60
Current EV/EBITDA
-7.18
Overvalued EV/EBITDA
-2.95
Undervalued EV/EBITDA
-6.25

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
309.82
Current PS
3.36
Overvalued PS
1025.94
Undervalued PS
-406.30

Financials

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Whales Holding SNDX

W
Wiener Städtische Wechselseitige Versicherungsverein - Vermögensverwaltung - Vienna Insurance Group
Holding
SNDX
+36.43%
3M Return
V
Voss Capital, LP
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Kynam Capital Management, LP
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Frequently Asked Questions

What is Syndax Pharmaceuticals Inc (SNDX) stock price today?

The current price of SNDX is 19.59 USD — it has decreased -0.81

What is Syndax Pharmaceuticals Inc (SNDX)'s business?

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

What is the price predicton of SNDX Stock?

Wall Street analysts forecast SNDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNDX is39.11 USD with a low forecast of 27.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Syndax Pharmaceuticals Inc (SNDX)'s revenue for the last quarter?

Syndax Pharmaceuticals Inc revenue for the last quarter amounts to 64.86M USD, increased 223.64

What is Syndax Pharmaceuticals Inc (SNDX)'s earnings per share (EPS) for the last quarter?

Syndax Pharmaceuticals Inc. EPS for the last quarter amounts to -0.48 USD, decreased -51.02

How many employees does Syndax Pharmaceuticals Inc (SNDX). have?

Syndax Pharmaceuticals Inc (SNDX) has 298 emplpoyees as of May 30 2026.

What is Syndax Pharmaceuticals Inc (SNDX) market cap?

Today SNDX has the market capitalization of 1.74B USD.