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SNDX Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
25.160
Open
23.880
VWAP
24.21
Vol
1.79M
Mkt Cap
2.13B
Low
23.300
Amount
43.23M
EV/EBITDA(TTM)
--
Total Shares
88.20M
EV
2.04B
EV/OCF(TTM)
--
P/S(TTM)
11.99
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Show More

Events Timeline

(ET)
2026-02-26
16:30:00
Syndax Reports Q4 Revenue of $68.73M, Beating Consensus
select
2026-02-26
16:30:00
Syndax Expects FY26 R&D and SG&A Expenses of Approximately $400M
select
2026-01-12 (ET)
2026-01-12
07:10:00
Syndax Updates 2026 Business Priorities and Milestones
select
2026-01-12
07:10:00
Niktimvo Reports Preliminary Q4 Revenue of $56M
select
2026-01-07 (ET)
2026-01-07
07:10:00
Syndax Partners with WODA to Expand Access to Revuforj
select

News

Yahoo Finance
8.5
03-04Yahoo Finance
Syndax Pharmaceuticals Grants Stock Options to New Employees
  • Stock Option Grant: On March 1, 2026, Syndax Pharmaceuticals granted inducement awards for up to 81,600 shares of common stock to three new employees, aimed at attracting and retaining key talent, thereby enhancing the company's innovative capabilities and market competitiveness.
  • Vesting Schedule: The stock options will vest over four years, with 25% of the shares vesting on the one-year anniversary of the vesting commencement date, and the remaining shares vesting monthly over the next 36 months, ensuring continued employee contributions during their service.
  • Innovative Drug Pipeline: Syndax's pipeline includes FDA-approved drugs Revuforj® and Niktimvo™, indicating the company's ongoing investment and research capabilities in cancer treatment, aimed at meeting market demands for new therapies.
  • Clinical Trial Advancement: The company is conducting several clinical trials to unlock the full potential of its pipeline, further driving innovation in cancer treatment and improving patient outcomes and quality of life.
NASDAQ.COM
2.0
02-27NASDAQ.COM
Syndax (SNDX) Q4 2025 Earnings Call Transcript
seekingalpha
9.5
02-27seekingalpha
Syndax Pharmaceuticals Q4 2025 Earnings Call Highlights
  • Significant Revenue Growth: Syndax Pharmaceuticals reported total revenue of $172.4 million for 2025, with Revuforj net revenue reaching $124.8 million, reflecting a 38% year-over-year increase, indicating strong market demand and product uptake that is expected to drive continued growth.
  • Outstanding Niktimvo Performance: Niktimvo generated $152 million in net revenue in the first 11 months of 2025, surpassing the benchmark set by Sanofi's REZUROCK, demonstrating Syndax's competitive edge and rapid market share expansion in the new drug sector.
  • Sustained R&D Investment: With $394 million in cash and equivalents at the end of 2025, the company is well-positioned to meet its funding needs for future R&D and market expansion, supporting its strategic goal of targeting a total addressable market exceeding $10 billion.
  • Clinical Trial Progress: Enrollment for the MAXPIRe Phase II trial has been completed, with topline data expected in Q4 2026, which will provide critical data support for the company's further development in specific disease areas.
NASDAQ.COM
9.5
02-27NASDAQ.COM
Syndax Pharma Reports Q4 Loss and Revenue Surge
  • Financial Performance: Syndax Pharma reported a Q4 net loss of $68.01 million, or $0.78 per share, which is an improvement from last year's loss of $94.17 million and $1.10 per share, indicating progress in loss control.
  • Revenue Surge: The company's Q4 revenue soared to $68.73 million, a staggering 794.9% increase from $7.68 million last year, reflecting strong product sales and market demand recovery, potentially laying the groundwork for future profitability.
  • Improved Profitability: Although still in the red, the reduced loss compared to last year suggests that Syndax Pharma has made strides in cost management and operational efficiency, which may attract more investor interest in its growth potential.
  • Market Outlook: With rapid revenue growth and shrinking losses, Syndax Pharma's competitive position in the biopharmaceutical sector is expected to strengthen, particularly in new product launches and market expansion, potentially leading to greater market share.
seekingalpha
9.5
02-26seekingalpha
Syndax Pharmaceuticals Reports Q4 Earnings and 2026 Outlook
  • Earnings Report: Syndax Pharmaceuticals reported a Q4 GAAP EPS of -$0.78, missing expectations by $0.23, indicating challenges in profitability that may affect investor confidence.
  • Revenue Surge: The company achieved Q4 revenue of $68.7 million, a staggering 794.5% increase year-over-year, surpassing estimates by $3.95 million, reflecting significant market acceptance of its products and laying a foundation for future growth.
  • Expense Forecast: Syndax anticipates total research and development plus selling, general, and administrative expenses to reach approximately $400 million in 2026, excluding an estimated $50 million in non-cash stock compensation, which could exert pressure on the company's cash flow.
  • Market Outlook: Despite profitability challenges, Syndax's early market performance signals continued growth potential, particularly with product launches in 2026, which may attract increased investor interest.
seekingalpha
9.5
02-25seekingalpha
Syndax Pharmaceuticals Q4 Earnings Preview
  • Earnings Announcement Date: Syndax Pharmaceuticals (SNDX) is set to announce its Q4 earnings on February 26th after market close, with a consensus EPS estimate of -$0.58, reflecting a 47.3% year-over-year improvement, indicating potential profitability enhancement.
  • Significant Revenue Growth Expected: The anticipated revenue for Q4 is $64.75 million, representing a staggering 743.1% year-over-year increase, which underscores the company's remarkable growth in market demand and product sales, potentially bolstering investor confidence.
  • Performance Beat Record: Over the past year, SNDX has beaten EPS estimates 50% of the time and revenue estimates 25% of the time, suggesting a degree of stability in financial performance and potential upside for investors.
  • Estimate Revision Dynamics: In the last three months, EPS estimates have seen four upward revisions and two downward adjustments, while revenue estimates have experienced four upward revisions and one downward, reflecting fluctuations in analyst confidence regarding the company's future performance, which may influence investor decisions.
Wall Street analysts forecast SNDX stock price to rise
10 Analyst Rating
Wall Street analysts forecast SNDX stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
JPMorgan
Overweight
upgrade
$33 -> $45
AI Analysis
2026-03-09
New
Reason
JPMorgan
Price Target
$33 -> $45
AI Analysis
2026-03-09
New
upgrade
Overweight
Reason
JPMorgan raised the firm's price target on Syndax to $45 from $33 and keeps an Overweight rating on the shares. The Phase 2 MAXPIRe data for Niktimvo in idiopathic pulmonary fibrosis is expected in Q4, the analyst tells investors in a research note. The firm says that at current share levels, no value being ascribed for the Niktimvo IPF opportunity. Hence, the phase 2 MAXPIRe "card flip is essentially a free call option," contends JPMorgan. It sees the value of Revuforj and Niktimvo in the refractory commercial setting alone being in the high-$20s to low-$30s per share range.
Citi
Buy
upgrade
$51 -> $57
2026-03-02
Reason
Citi
Price Target
$51 -> $57
2026-03-02
upgrade
Buy
Reason
Citi raised the firm's price target on Syndax to $57 from $51 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SNDX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX.O) is -11.30, compared to its 5-year average forward P/E of -6.96. For a more detailed relative valuation and DCF analysis to assess Syndax Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.96
Current PE
-11.30
Overvalued PE
-3.46
Undervalued PE
-10.46

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.23
Current EV/EBITDA
-9.32
Overvalued EV/EBITDA
-0.52
Undervalued EV/EBITDA
-7.94

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
334.89
Current PS
5.81
Overvalued PS
1059.18
Undervalued PS
-389.40

Financials

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Whales Holding SNDX

W
Wiener Städtische Wechselseitige Versicherungsverein - Vermögensverwaltung - Vienna Insurance Group
Holding
SNDX
+7.33%
3M Return
K
Kynam Capital Management, LP
Holding
SNDX
+6.22%
3M Return
Y
Yelin Lapidot Holdings Ltd.
Holding
SNDX
-0.61%
3M Return
B
Brevan Howard Capital Management LP
Holding
SNDX
-0.68%
3M Return
E
Eversept Partners, L.P.
Holding
SNDX
-0.87%
3M Return
S
Soleus Capital Management, L.P.
Holding
SNDX
-5.17%
3M Return

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Frequently Asked Questions

What is Syndax Pharmaceuticals Inc (SNDX) stock price today?

The current price of SNDX is 24.16 USD — it has increased 1.17

What is Syndax Pharmaceuticals Inc (SNDX)'s business?

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

What is the price predicton of SNDX Stock?

Wall Street analysts forecast SNDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNDX is39.11 USD with a low forecast of 27.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Syndax Pharmaceuticals Inc (SNDX)'s revenue for the last quarter?

Syndax Pharmaceuticals Inc revenue for the last quarter amounts to 68.73M USD, increased 794.90

What is Syndax Pharmaceuticals Inc (SNDX)'s earnings per share (EPS) for the last quarter?

Syndax Pharmaceuticals Inc. EPS for the last quarter amounts to -0.78 USD, decreased -28.44

How many employees does Syndax Pharmaceuticals Inc (SNDX). have?

Syndax Pharmaceuticals Inc (SNDX) has 298 emplpoyees as of March 11 2026.

What is Syndax Pharmaceuticals Inc (SNDX) market cap?

Today SNDX has the market capitalization of 2.13B USD.