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SNDX

Syndax Pharmaceuticals Inc
$
9.980
+0.06(0.605%)1D
  • Overview
  • Forecast
  • Valuation
  • Earnings
Line
Line
|
Candle
Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
10.005
Open
9.9361
VWAP
9.78
Vol
1.70M
Mkt Cap
858.75M
Low
9.490
Amount
16.60M
EV/EBITDA(TTM)
--
Total Shares
84.99M
EV
682.53M
EV/OCF(TTM)
--
P/S(TTM)
19.48
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
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Market Estimates

Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q2
FY2025Q3
FY2025Q4
27.09M
+674.1%
-0.995
+24.39%
33.24M
+165.92%
-0.928
-5.34%
--
--
-0.877
-20.3%
Estimates Revision
The market is revising Upward the revenue expectations for Syndax Pharmaceuticals, Inc. (SNDX) for FY2025, with the revenue forecasts being adjusted by 37.95% over the past three months. During the same period, the stock price has changed by -27.79%.
Revenue Estimates for FY2025
Revise Upward
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+37.95%
In Past 3 Month
EPS Estimates for FY2025
Revise Upward
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+0.24%
In Past 3 Month
Stock Price
Go Down
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-27.79%
In Past 3 Month
10 Analyst Rating
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217.33% Upside
Wall Street analysts forecast SNDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNDX is 31.67 USD with a low forecast of 17.00 USD and a high forecast of 45.00  USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
9 Buy
1 Hold
0 Sell
Strong Buy
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217.33% Upside
Current: 9.980
sliders
Low
17.00
Averages
31.67
High
45.00
UBS
David Dai
Buy
downgrade
$37 -> $35
2025-07-15
Reason
UBS analyst David Dai lowered the firm's price target on Syndax to $35 from $37 and keeps a Buy rating on the shares. UBS expects Syndax to report in-line Q2 results with $25M in Revuforj sales and $2.7M in Niktimvo revenue, but thinks Niktimvo sales could surprise to the upside even the strong Q1 launch, the analyst tells investors in a research note.
Goldman Sachs
Corinne Johnson
initiated
$18
2025-07-10
Reason
Goldman Sachs analyst Corinne Johnson initiated coverage of Syndax with a Buy rating and $18 price target, implying 100% upside potential. The firm's positive view is based on the near-term and peak revenue opportunity for Revuforj, Syndax's wholly-owned lead drug currently approved for the treatment of relapsed/refractory acute myeloid leukemia patients. It estimates peak sales at $1.1B before considering potential use in the frontline setting.
JP Morgan
Anupam Rama
Buy
Maintains
$39 → $41
2025-03-20
Reason
JPMorgan raised the firm's price target on Syndax to $41 from $39 and keeps an Overweight rating on the shares after having surveyed 23 U.S. hematologists to better understand the launch prospects of Revuforj in relapsed/refractory KMT2A acute leukemias and NPM1-mutated acute myeloid leukemia. Overall, surveyed physicians provided high ratings related to the clinical profile of Revuforj in both indications, the analyst tells investors.
HC Wainwright & Co.
Edward White
Strong Buy
Reiterates
$51
2025-03-04
Reason
Citigroup
Yigal Nochomovitz
Strong Buy
Maintains
$45 → $42
2025-03-04
Reason
Citi lowered the firm's price target on Syndax to $42 from $45 and keeps a Buy rating on the shares post the Q4 report. The firm says the stock's "non-reaction" to Syndax's first print for Revuforj that handily beat consensus reflects the lack of incremental buyers who see relapsed or refractory KMT2A-rearranged leukemia as too narrow despite first-to-market advantage and early strong commercial execution. Citi believes it may take time for the NPM1 launch to "move the needle."
JP Morgan
Anupam Rama
Buy
Maintains
$35 → $39
2025-03-04
Reason
JPMorgan raised the firm's price target on Syndax to $39 from $35 and keeps an Overweight rating on the shares. The firm updated models in the Smid-cap biotechnology group post the Q4 reports.

Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX.O) is -2.71, compared to its 5-year average forward P/E of -7.84. For a more detailed relative valuation and DCF analysis to assess Syndax Pharmaceuticals Inc 's fair value, click here.

Forward PE

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.84
Current PE
-2.71
Overvalued PE
-2.47
Undervalued PE
-13.21

Forward EV/EBITDA

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.23
Current EV/EBITDA
-2.37
Overvalued EV/EBITDA
3.70
Undervalued EV/EBITDA
-10.17

Forward PS

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
424.69
Current PS
5.89
Overvalued PS
1200.19
Undervalued PS
-350.81

Financials

Annual
Quarterly
FY2025Q1
20.04M
Total Revenue
FY2025Q1
YoY :
+5.03%
-83.51M
Operating Profit
FY2025Q1
YoY :
+17.19%
-84.85M
Net Income after Tax
FY2025Q1
YoY :
+15.29%
-0.98
EPS - Diluted
FY2025Q1
YoY :
+13.90%
-95.16M
Free Cash Flow
FY2025Q1
95.58
Gross Profit Margin - %
FY2025Q1
-655.32
FCF Margin - %
FY2025Q1
-423.34
Net Margin - %

Trading Trends

Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
82.0K
USD
2
3-6
Months
117.6K
USD
1
6-9
Months
336.2K
USD
3
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
3
241.9K
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
1.7M
Volume
1
6-9
Months
11.4M
Volume
7
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
3
2.5M
Volume
Months
6-9
2
4.1M
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months

SNDX News & Events

Events Timeline

2025-06-24 (ET)
2025-06-24
16:07:56
Syndax granted priority review for Revuforj sNDA by FDA
select
2025-06-12 (ET)
2025-06-12
12:07:17
Syndax reports publication of revumenib data from BEAT AML trial
select
2025-06-12
07:05:53
Syndax announces new data from AUGMENT-101 trial of Revuforj
select
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News

4.0
07-11TipRanks
SNDX, NUVB, AURA : 3 Russell 2000 Stocks Analysts Say Could Soar Over 200%
6.0
07-10Benzinga
Goldman Sachs Initiates Coverage On Syndax Pharmaceuticals with Buy Rating, Announces Price Target of $18
9.0
06-25NASDAQ.COM
FDA Grants Priority Review To Syndax's Revuforj For R/R MNPM1 Acute Myeloid Leukemia Treatment
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FAQ

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The current price of SNDX is 9.98 USD — it has increased 0.6 % in the last trading day.

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