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SNDX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
23.950
Open
23.480
VWAP
23.66
Vol
213.90K
Mkt Cap
1.98B
Low
23.340
Amount
5.06M
EV/EBITDA(TTM)
--
Total Shares
88.20M
EV
1.91B
EV/OCF(TTM)
--
P/S(TTM)
11.28
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Show More

Events Timeline

(ET)
2026-02-26
16:30:00
Syndax Expects FY26 R&D and SG&A Expenses of Approximately $400M
select
2026-02-26
16:30:00
Syndax Reports Q4 Revenue of $68.73M, Beating Consensus
select
2026-01-12 (ET)
2026-01-12
07:10:00
Syndax Updates 2026 Business Priorities and Milestones
select
2026-01-12
07:10:00
Niktimvo Reports Preliminary Q4 Revenue of $56M
select

News

Fool
6.5
03-22Fool
DAFNA Capital Reduces Stake in Syndax Pharmaceuticals
  • Share Reduction Details: DAFNA Capital reported in its February 17, 2026 SEC filing that it sold 222,847 shares of Syndax Pharmaceuticals in Q4, with an estimated transaction value of $3.89 million, reflecting a cautious outlook on the company's future performance.
  • Ownership Percentage Change: Following the sale, DAFNA's stake in Syndax decreased to 1.36% from 1.90% in the previous quarter, indicating a strategic adjustment in its investment portfolio.
  • Market Performance Comparison: As of last Friday, Syndax's stock price stood at $24.23, marking a 72% increase over the past year, significantly outperforming the S&P 500's 15% rise during the same period, highlighting its strong position in the biopharmaceutical sector.
  • Company Growth Prospects: Syndax focuses on developing oncology therapies, and despite facing high operating costs and ongoing losses, its $172 million in 2025 sales and rapidly scaling commercial products demonstrate its potential in transitioning from clinical to commercial-stage biotech.
NASDAQ.COM
6.5
03-22NASDAQ.COM
DAFNA Capital Management Reduces SNDX Holdings
  • Share Reduction Details: DAFNA Capital Management sold 222,847 shares of Syndax Pharmaceuticals (SNDX) in Q4, with an estimated transaction value of approximately $3.89 million, indicating a cautious stance towards the stock.
  • Position Value Decline: The value of DAFNA's SNDX holdings decreased by $1.87 million by quarter-end, reflecting both trading activities and price movements, with the current position representing 1.4% of reportable AUM.
  • Company Overview: Syndax Pharmaceuticals focuses on developing novel cancer therapies, generating approximately $172 million in sales for 2025, showcasing a successful transition from clinical to commercial stages, albeit with higher operating costs and ongoing losses.
  • Investor Caution: Despite Syndax's innovative potential in the biopharmaceutical sector, it was not included in the current top investment stock list by analysts, advising investors to carefully consider market volatility before making decisions.
Fool
6.5
03-21Fool
Kynam Capital Management Reduces Syndax Holdings
  • Share Reduction Details: Kynam Capital Management disclosed in a February 17, 2026 SEC filing that it sold 469,041 shares of Syndax Pharmaceuticals, valued at approximately $8.18 million, indicating a cautious stance towards the company's future prospects.
  • Position Percentage Change: Following the sale, Syndax now accounts for 10.81% of Kynam's reportable assets, reflecting a significant yet measured adjustment in their holdings, which still signals confidence in the company's long-term potential.
  • Company Financial Performance: Syndax Pharmaceuticals has seen its stock price surge 72% over the past year, achieving a market capitalization of $2.1 billion and total revenue of $172.4 million, despite a net loss of $285.4 million, highlighting the tension between growth and profitability.
  • Market Reaction Analysis: The successful launch of new therapies has driven revenue growth for Syndax, particularly with Revuforj contributing approximately $124.8 million, although the company continues to face high R&D and commercialization costs, necessitating investor attention on its path to profitability.
NASDAQ.COM
6.5
03-21NASDAQ.COM
Kynam Capital Reduces Syndax Stake
  • Share Reduction Transaction: Kynam Capital reduced its stake in Syndax Pharmaceuticals by 469,041 shares in Q4 2025, with an estimated trade value of $8.18 million, reflecting the fund's flexible adjustment strategy amid market fluctuations.
  • Holding Value Increase: Despite the reduction, Kynam Capital's position in Syndax saw a quarter-end value increase of $38.07 million, indicating strong stock performance and positive impacts from trading activities.
  • Company Financial Performance: Syndax Pharmaceuticals generated approximately $172 million in total revenue last year, with Revuforj contributing about $124.8 million, showcasing growing market acceptance of its new therapies, although the company still faced a net loss of around $285 million.
  • Portfolio Adjustment: Kynam Capital's Syndax holdings still account for over 10% of its assets, indicating that despite the reduction, the fund maintains confidence in the company's long-term prospects, reflecting a strategic positioning within the biotech sector.
Yahoo Finance
6.5
03-21Yahoo Finance
Kynam Capital Management Cuts Viridian Stake by Over $81 Million
  • Stake Reduction: Kynam Capital Management sold 2,957,386 shares of Viridian Therapeutics in Q4 2026, with an estimated transaction value of $81.11 million, indicating a cautious outlook on the company's future performance.
  • Holding Proportion Change: Following this transaction, Kynam's stake in Viridian decreased to 2.92%, reflecting a reassessment of asset allocation in its 13F report, which may impact investor confidence in the company.
  • Market Performance: Viridian's stock price has surged 76% over the past year, currently priced at $26.98, significantly outperforming the S&P 500's roughly 15% gain, indicating strong market demand for its biotech products.
  • R&D Expenditure: Despite facing nearly $339 million in R&D costs and an annual net loss of about $343 million, Viridian's cash reserves of approximately $875 million at year-end provide a financial cushion for future clinical trials and product launches.
Yahoo Finance
6.5
03-21Yahoo Finance
Kynam Capital Reduces Stake in Cogent Biosciences by $48 Million
  • Share Reduction Details: Kynam Capital disclosed in an SEC filing on February 17, 2026, that it sold 1,720,949 shares of Cogent Biosciences in Q4, with an estimated transaction value of $48.38 million, indicating a cautious approach towards the company's future prospects.
  • Ownership Proportion Change: Following this sale, Cogent Biosciences now represents 13.99% of Kynam's reported AUM, yet it remains the fund's largest holding, reflecting ongoing confidence in its core investment despite the reduction.
  • Market Performance Analysis: Cogent's stock price surged 360% over the past year, significantly outperforming the S&P 500's 15% gain during the same period, highlighting its strong performance and market recognition in the biotech sector.
  • Future Outlook: Cogent's lead product, bezuclastinib, received FDA acceptance, with a target decision date set for December 30, 2026, and with $900.8 million in cash reserves, the company is well-positioned to support future R&D and market expansion efforts.
Wall Street analysts forecast SNDX stock price to rise
10 Analyst Rating
Wall Street analysts forecast SNDX stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Mizuho
Outperform
to
Outperform
downgrade
$45 -> $43
AI Analysis
2026-03-31
New
Reason
Mizuho
Price Target
$45 -> $43
AI Analysis
2026-03-31
New
downgrade
Outperform
to
Outperform
Reason
Mizuho lowered the firm's price target on Syndax to $43 from $45 and keeps an Outperform rating on the shares. The firm updated models in the small-cap biotech space following the Q4 reports.
Goldman Sachs
Corinne Johnson
Buy
maintain
$28 -> $34
2026-03-31
New
Reason
Goldman Sachs
Corinne Johnson
Price Target
$28 -> $34
2026-03-31
New
maintain
Buy
Reason
Goldman Sachs analyst Corinne Johnson raised the firm's price target on Syndax to $34 from $28 and keeps a Buy rating on the shares. Ahead of Syndax's Phase 2 data for axatilimab in idiopathic pulmonary fibrosis expected in 4Q26, peak sales estimates have been increased by $325M on a risk-adjusted basis, reflecting growing focus on the program, the analyst tells investors in a research note. While Revuforj in relapsed/refractory leukemias remains central to the story, early launch metrics in KMT2A- and NPM1-mutated AML appear strong, and the mechanistic rationale for CSF-1R inhibition in IPF supports confidence in the program's potential path to Phase 3 success, the firm says.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SNDX
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Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX.O) is -11.30, compared to its 5-year average forward P/E of -6.67. For a more detailed relative valuation and DCF analysis to assess Syndax Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.67
Current PE
-11.30
Overvalued PE
-4.29
Undervalued PE
-9.05

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.60
Current EV/EBITDA
-9.32
Overvalued EV/EBITDA
-2.92
Undervalued EV/EBITDA
-6.28

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
338.95
Current PS
5.81
Overvalued PS
1066.90
Undervalued PS
-389.00

Financials

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Whales Holding SNDX

W
Wiener Städtische Wechselseitige Versicherungsverein - Vermögensverwaltung - Vienna Insurance Group
Holding
SNDX
-0.70%
3M Return
K
Kynam Capital Management, LP
Holding
SNDX
-2.15%
3M Return
E
Eversept Partners, L.P.
Holding
SNDX
-7.31%
3M Return
S
Soleus Capital Management, L.P.
Holding
SNDX
-7.51%
3M Return
B
Brevan Howard Capital Management LP
Holding
SNDX
-8.98%
3M Return
Y
Yelin Lapidot Holdings Ltd.
Holding
SNDX
-9.09%
3M Return

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Frequently Asked Questions

What is Syndax Pharmaceuticals Inc (SNDX) stock price today?

The current price of SNDX is 23.68 USD — it has increased 5.34

What is Syndax Pharmaceuticals Inc (SNDX)'s business?

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

What is the price predicton of SNDX Stock?

Wall Street analysts forecast SNDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNDX is39.11 USD with a low forecast of 27.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Syndax Pharmaceuticals Inc (SNDX)'s revenue for the last quarter?

Syndax Pharmaceuticals Inc revenue for the last quarter amounts to 68.73M USD, increased 794.90

What is Syndax Pharmaceuticals Inc (SNDX)'s earnings per share (EPS) for the last quarter?

Syndax Pharmaceuticals Inc. EPS for the last quarter amounts to -0.78 USD, decreased -28.44

How many employees does Syndax Pharmaceuticals Inc (SNDX). have?

Syndax Pharmaceuticals Inc (SNDX) has 298 emplpoyees as of March 31 2026.

What is Syndax Pharmaceuticals Inc (SNDX) market cap?

Today SNDX has the market capitalization of 1.98B USD.