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SNDX Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
21.860
Open
20.540
VWAP
21.28
Vol
2.18M
Mkt Cap
1.90B
Low
20.480
Amount
46.34M
EV/EBITDA(TTM)
--
Total Shares
88.61M
EV
1.89B
EV/OCF(TTM)
--
P/S(TTM)
8.61
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Show More

Events Timeline

(ET)
2026-04-30
16:30:00
Company Reports Q1 Revenue of $64.86M, Below Expectations
select
2026-02-26 (ET)
2026-02-26
16:30:00
Syndax Expects FY26 R&D and SG&A Expenses of Approximately $400M
select

News

seekingalpha
9.5
05-01seekingalpha
Syndax Pharmaceuticals Q1 2026 Earnings Call Highlights
  • Strong Sales Performance: Syndax Pharmaceuticals achieved over $100 million in combined sales of Revuforj and Niktimvo in Q1 2026, demonstrating robust demand for both medicines and advancing the company towards profitability.
  • Revuforj Revenue Growth: Revuforj net revenue reached $49 million, significantly increasing the estimate of KMT2A patients able to receive potentially curative stem cell transplants to nearly 50%, up from the previous estimate of 33%, indicating improved treatment efficacy.
  • Stable Niktimvo Performance: Niktimvo delivered $55 million in net revenue in Q1, reflecting consistent new patient starts despite natural attrition, suggesting strong ongoing market demand.
  • Sufficient Funding: As of March 31, 2026, the company reported $352.1 million in cash, cash equivalents, and marketable securities, ensuring the ability to continue investing in its R&D and commercial priorities.
seekingalpha
9.5
04-30seekingalpha
Syndax Pharmaceuticals Q1 Earnings Beat Expectations
  • Earnings Highlights: Syndax Pharmaceuticals reported a Q1 GAAP EPS of -$0.48, beating expectations by $0.13, indicating an improving trend in the company's profitability.
  • Revenue Surge: The company achieved revenue of $64.9 million in Q1, representing a remarkable year-over-year growth of 223.9%, although it fell short of expectations, reflecting strong market demand for its products.
  • Expense Forecast: For the full year 2026, total research and development plus selling, general, and administrative expenses are expected to be approximately $400 million, excluding an estimated $50 million in non-cash stock compensation, highlighting the company's ongoing investment in business expansion.
  • Market Outlook: Despite missing revenue expectations, Syndax's robust growth momentum and upcoming drug launches may attract investor interest and enhance market confidence.
Newsfilter
9.5
04-24Newsfilter
Syndax Pharmaceuticals to Report Q1 2026 Financial Results
  • Earnings Release Schedule: Syndax Pharmaceuticals is set to announce its Q1 2026 financial results on April 30, 2026, which is expected to significantly impact investor sentiment.
  • Conference Call Details: Management will host a conference call and live audio webcast at 4:30 p.m. ET on the same day, providing investors with direct access to company updates and enhancing transparency.
  • Replay Availability: For those unable to attend the live session, a replay will be accessible approximately 24 hours post-call and will remain available for 90 days, ensuring widespread dissemination of critical information.
  • Pipeline Highlights: Syndax's pipeline features FDA-approved cancer therapies like Revuforj® and Niktimvo™, showcasing the company's ongoing commitment and potential in cancer treatment, which may attract increased investor interest.
Fool
6.5
03-22Fool
DAFNA Capital Reduces Stake in Syndax Pharmaceuticals
  • Share Reduction Details: DAFNA Capital reported in its February 17, 2026 SEC filing that it sold 222,847 shares of Syndax Pharmaceuticals in Q4, with an estimated transaction value of $3.89 million, reflecting a cautious outlook on the company's future performance.
  • Ownership Percentage Change: Following the sale, DAFNA's stake in Syndax decreased to 1.36% from 1.90% in the previous quarter, indicating a strategic adjustment in its investment portfolio.
  • Market Performance Comparison: As of last Friday, Syndax's stock price stood at $24.23, marking a 72% increase over the past year, significantly outperforming the S&P 500's 15% rise during the same period, highlighting its strong position in the biopharmaceutical sector.
  • Company Growth Prospects: Syndax focuses on developing oncology therapies, and despite facing high operating costs and ongoing losses, its $172 million in 2025 sales and rapidly scaling commercial products demonstrate its potential in transitioning from clinical to commercial-stage biotech.
NASDAQ.COM
6.5
03-22NASDAQ.COM
DAFNA Capital Management Reduces SNDX Holdings
  • Share Reduction Details: DAFNA Capital Management sold 222,847 shares of Syndax Pharmaceuticals (SNDX) in Q4, with an estimated transaction value of approximately $3.89 million, indicating a cautious stance towards the stock.
  • Position Value Decline: The value of DAFNA's SNDX holdings decreased by $1.87 million by quarter-end, reflecting both trading activities and price movements, with the current position representing 1.4% of reportable AUM.
  • Company Overview: Syndax Pharmaceuticals focuses on developing novel cancer therapies, generating approximately $172 million in sales for 2025, showcasing a successful transition from clinical to commercial stages, albeit with higher operating costs and ongoing losses.
  • Investor Caution: Despite Syndax's innovative potential in the biopharmaceutical sector, it was not included in the current top investment stock list by analysts, advising investors to carefully consider market volatility before making decisions.
Fool
6.5
03-21Fool
Kynam Capital Management Reduces Syndax Holdings
  • Share Reduction Details: Kynam Capital Management disclosed in a February 17, 2026 SEC filing that it sold 469,041 shares of Syndax Pharmaceuticals, valued at approximately $8.18 million, indicating a cautious stance towards the company's future prospects.
  • Position Percentage Change: Following the sale, Syndax now accounts for 10.81% of Kynam's reportable assets, reflecting a significant yet measured adjustment in their holdings, which still signals confidence in the company's long-term potential.
  • Company Financial Performance: Syndax Pharmaceuticals has seen its stock price surge 72% over the past year, achieving a market capitalization of $2.1 billion and total revenue of $172.4 million, despite a net loss of $285.4 million, highlighting the tension between growth and profitability.
  • Market Reaction Analysis: The successful launch of new therapies has driven revenue growth for Syndax, particularly with Revuforj contributing approximately $124.8 million, although the company continues to face high R&D and commercialization costs, necessitating investor attention on its path to profitability.
Wall Street analysts forecast SNDX stock price to rise
10 Analyst Rating
Wall Street analysts forecast SNDX stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Current: 0.000
sliders
Low
27.00
Averages
39.11
High
56.00
Stifel
Buy
maintain
$45 -> $46
AI Analysis
2026-05-04
Reason
Stifel
Price Target
$45 -> $46
AI Analysis
2026-05-04
maintain
Buy
Reason
Stifel raised the firm's price target on Syndax to $46 from $45 and keeps a Buy rating on the shares. Despite modest consensus misses on Revuforj and Niktimvo sales weighing on shares, the firm is "incrementally" more positive and confident in the trajectory of the Revuforj, the analyst tells investors.
Jefferies
Buy
downgrade
$40 -> $37
2026-05-01
Reason
Jefferies
Price Target
$40 -> $37
2026-05-01
downgrade
Buy
Reason
Jefferies lowered the firm's price target on Syndax to $37 from $40 and keeps a Buy rating on the shares following Q1 results. The firm noted that the revuforj revenue miss was due to approximately 50% of KMT2A patients going to transplant. On the other hand, Jefferies told investors that the major silver lining is that these revenues should come back over time with post-transplant maintenance, plus NPM1 patient adds growing nicely.
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Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX.O) is 0.00, compared to its 5-year average forward P/E of -6.64. For a more detailed relative valuation and DCF analysis to assess Syndax Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.64
Current PE
0.00
Overvalued PE
-4.25
Undervalued PE
-9.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.58
Current EV/EBITDA
-7.03
Overvalued EV/EBITDA
-2.95
Undervalued EV/EBITDA
-6.21

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
314.41
Current PS
3.32
Overvalued PS
1029.77
Undervalued PS
-400.96

Financials

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Whales Holding SNDX

W
Wiener Städtische Wechselseitige Versicherungsverein - Vermögensverwaltung - Vienna Insurance Group
Holding
SNDX
+29.25%
3M Return
B
Brevan Howard Capital Management LP
Holding
SNDX
+16.14%
3M Return
S
Soleus Capital Management, L.P.
Holding
SNDX
+8.19%
3M Return
V
Voss Capital, LP
Holding
SNDX
+0.28%
3M Return
E
Eversept Partners, L.P.
Holding
SNDX
-4.67%
3M Return

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Frequently Asked Questions

What is Syndax Pharmaceuticals Inc (SNDX) stock price today?

The current price of SNDX is 21.49 USD — it has increased 4.63

What is Syndax Pharmaceuticals Inc (SNDX)'s business?

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

What is the price predicton of SNDX Stock?

Wall Street analysts forecast SNDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNDX is39.11 USD with a low forecast of 27.00 USD and a high forecast of 56.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Syndax Pharmaceuticals Inc (SNDX)'s revenue for the last quarter?

Syndax Pharmaceuticals Inc revenue for the last quarter amounts to 64.86M USD, increased 223.64

What is Syndax Pharmaceuticals Inc (SNDX)'s earnings per share (EPS) for the last quarter?

Syndax Pharmaceuticals Inc. EPS for the last quarter amounts to -0.48 USD, decreased -51.02

How many employees does Syndax Pharmaceuticals Inc (SNDX). have?

Syndax Pharmaceuticals Inc (SNDX) has 298 emplpoyees as of May 10 2026.

What is Syndax Pharmaceuticals Inc (SNDX) market cap?

Today SNDX has the market capitalization of 1.90B USD.