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ZYME Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
27.890
Open
27.760
VWAP
27.72
Vol
311.83K
Mkt Cap
2.07B
Low
27.430
Amount
8.64M
EV/EBITDA(TTM)
--
Total Shares
74.30M
EV
1.82B
EV/OCF(TTM)
--
P/S(TTM)
19.95
Zymeworks Inc. is a biotechnology company. The Company is engaged in managing a portfolio of healthcare assets and developing a pipeline of multifunctional biotherapeutics to improve the standard of care for conditions, including cancer, inflammation, and autoimmune disease. Its antibody-drug conjugates (ADCs) include ZW191, ZW251, and ZW220. ZW191 is a clinical-stage ADC that targets folate receptor alpha-expressing tumors including ovarian cancer, endometrial cancer, and non-small cell lung cancer (NSCLC), which is built using bystander-active, TOPO1i payload technology, ZD06519. ZW251 is a clinical-stage ADC molecule designed for the treatment of glypican 3 (GPC3)-expressing hepatocellular carcinoma (HCC). ZW220 is an ADC that targets NaPi2b-expressing NSCLC and ovarian cancer, built using bystander active TOPO1i payload technology, ZD06519. Its therapeutic platforms can be used to develop multifunctional fit-for-purpose biotherapeutics with bispecific capabilities.
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Events Timeline

(ET)
2026-04-09
06:10:00
Zymeworks Appoints Adam Schayowitz and Scott Platshon as Full-Time Executives
select
2026-04-07 (ET)
2026-04-07
13:30:00
Gilead to Acquire Tubulis for $3.15B
select
2026-04-01 (ET)
2026-04-01
06:10:00
Zymeworks Appoints Kristin Stafford as CFO
select
2026-03-30 (ET)
2026-03-30
06:10:00
Zymeworks' ZW191 Receives FDA Fast Track Designation
select
2026-03-30
06:10:00
Zymeworks Receives FDA Fast Track Designation for ZW191
select
2026-03-18 (ET)
2026-03-18
07:50:00
Zymeworks Partner Jazz Pharmaceuticals to Present Ziihera Clinical Trial Data at AACR Annual Meeting
select
2026-03-02 (ET)
2026-03-02
09:00:00
Stock Futures Drop Sharply as Geopolitical Risks Escalate
select

News

Newsfilter
8.5
04-17Newsfilter
Zymeworks Showcases Next-Generation ADC Programs at AACR 2026
  • Next-Gen ADC Showcase: Zymeworks presented six posters at the AACR 2026 Annual Meeting, highlighting its antibody-drug conjugate (ADC) and payload development programs, emphasizing innovative potential in treating RAS-driven cancers.
  • ZW191 Clinical Progress: ZW191, an FRα-targeting ADC, demonstrates favorable tolerability and efficacy when combined with standard therapies, supporting its further development in clinical stages.
  • Targeted Innovations: Newly developed ADCs targeting Ly6E, CLDN18.2, and PTK7 show strong anti-tumor activity across various solid tumor models, potentially offering new treatment options for difficult-to-treat cancers.
  • Future Outlook: Zymeworks plans to present updated clinical data on ZW191 during an oral presentation on April 21, 2026, further validating the efficacy and safety of its ADC platform and advancing the company's strategic development in the biotechnology sector.
Newsfilter
9.5
04-16Newsfilter
Zymeworks to Report Q1 2026 Financial Results on May 7
  • Earnings Announcement: Zymeworks will report its Q1 2026 financial results after market close on May 7, 2026, which is expected to provide investors with insights into the company's financial health and business progress.
  • Conference Call Details: Following the earnings release, management will host a conference call and webcast at 4:30 PM ET on the same day to discuss financial results and provide corporate updates, enhancing transparency and investor confidence.
  • Pipeline Development: Zymeworks is advancing its pipeline of multifunctional biotherapeutics, particularly innovative drugs targeting difficult-to-treat diseases like Ziihera®, indicating the company's ongoing innovation and competitiveness in the biotechnology sector.
  • Strategic Partnerships: The company has entered exclusive development and commercialization agreements with BeOne Medicines and Jazz Pharmaceuticals, showcasing its strategic positioning and market expansion capabilities in the global biopharmaceutical landscape.
Newsfilter
5.0
04-09Newsfilter
Zymeworks Appoints New Heads of R&D and Business
  • Executive Appointments: Zymeworks has officially appointed Dr. Adam Schayowitz as Head of R&D and Mr. Scott Platshon as Chief Business Officer as of April 9, 2026, aiming to enhance the company's execution and strategic positioning in the biotherapeutics sector.
  • R&D Strategy: Dr. Schayowitz will leverage nearly two decades of oncology drug development experience to advance the clinical progression of the company's product candidates, particularly in areas of high unmet need, thereby enhancing the company's competitive edge in the market.
  • Asset Management: Mr. Platshon is tasked with managing Zymeworks' asset aggregation strategy, which is expected to drive cash flows from products like Ziihera®, contributing to long-term shareholder value growth.
  • Strategic Integration: These executive changes align with Zymeworks' overall strategy, aiming to optimize future cash flows and support ongoing investments in innovative therapeutics through the integration of R&D innovation and strategic collaborations.
seekingalpha
5.0
04-01seekingalpha
Zymeworks Appoints Kristin Stafford as CFO Effective April 2026
  • Executive Change: Zymeworks has appointed Kristin Stafford as Chief Financial Officer effective April 1, 2026, bringing her experience from Royalty Pharma where she served as Senior Vice President and Chief Accounting Officer, which is expected to enhance the company's financial management capabilities.
  • Financial Performance Review: In its Q4 2025 earnings report, Zymeworks reported a GAAP EPS of -$0.55, missing expectations by $0.21, indicating challenges in achieving profitability and raising concerns among investors.
  • Revenue Shortfall: The company reported revenue of $2.52M, falling short of market expectations by $18.01M, highlighting significant deficiencies in revenue growth that could impact investor confidence moving forward.
  • Strategic Outlook: Zymeworks signals a milestone-driven expansion strategy with a potential of up to $1.5 billion by 2028, indicating a commitment to long-term growth despite current financial struggles.
NASDAQ.COM
5.0
04-01NASDAQ.COM
Zymeworks Appoints New CFO, Stock Rises
  • Executive Appointment: Zymeworks has appointed Kristin Stafford as Chief Financial Officer, bringing extensive experience from her previous role as Senior Vice President and Chief Accounting Officer at Royalty Pharma plc, which is expected to enhance the company's financial management.
  • Stock Performance: Following the announcement, Zymeworks' stock rose by $0.66, or 2.64%, in pre-market trading, indicating market optimism regarding the new CFO and confidence in the company's future growth.
  • FDA Fast Track Designation: On Monday, Zymeworks received FDA fast track designation for its antibody-drug conjugate ZW191, targeting advanced or metastatic platinum-resistant ovarian cancer, marking a significant advancement in the company's biotherapeutics pipeline that could expedite its market entry.
  • Market Outlook: With the fast track designation for ZW191, Zymeworks significantly enhances its market potential in cancer and autoimmune disease treatments, likely attracting more investor interest and further driving up the company's stock price.
Newsfilter
5.0
04-01Newsfilter
Zymeworks Appoints Kristin Stafford as CFO
  • Executive Appointment: Zymeworks has appointed Kristin Stafford as Chief Financial Officer, effective April 1, 2026, bringing extensive experience from the life sciences sector, particularly from her role at Royalty Pharma, where she excelled in strategic planning and capital allocation, which is expected to enhance the company's financial stability and strategic execution.
  • Strategic Background: During her tenure at Royalty Pharma, Stafford successfully executed complex capital market transactions and acquisitions, demonstrating her strong background in capital markets, which will provide crucial support for Zymeworks' capital operations and market expansion.
  • Business Development: Zymeworks focuses on developing multifunctional biotherapeutics, and Stafford's expertise will help optimize the company's asset portfolio and cash flows, particularly in its innovative drug pipeline, enhancing its position in the competitive biotechnology market.
  • Future Outlook: Zymeworks plans to leverage Stafford's leadership to strengthen capital allocation and operational excellence, driving long-term value creation, especially in the development of treatment solutions for difficult-to-treat diseases, showcasing the company's confidence in future growth.
Wall Street analysts forecast ZYME stock price to rise
14 Analyst Rating
Wall Street analysts forecast ZYME stock price to rise
14 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
35.55
High
42.00
Current: 0.000
sliders
Low
30.00
Averages
35.55
High
42.00
Evercore ISI
Outperform
maintain
$33 -> $48
AI Analysis
2026-03-09
Reason
Evercore ISI
Price Target
$33 -> $48
AI Analysis
2026-03-09
maintain
Outperform
Reason
Evercore ISI raised the firm's price target on Zymeworks (ZYME) to $48 from $33 and keeps an Outperform rating on the shares. The $250M debt deal with Royalty Pharma (RPRX) is "a smart move," providing significant optionality and the terms are "favorable," allowing Zymeworks to retain upside while strengthening its balance sheet, the analyst tells investors.
H.C. Wainwright
Buy
maintain
$32 -> $46
2026-03-06
Reason
H.C. Wainwright
Price Target
$32 -> $46
2026-03-06
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on Zymeworks to $46 from $32 and keeps a Buy rating on the shares post the Q4 report. The firm cites the company's shift towards a more royalty-focused strategy for the target boost.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ZYME
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Valuation Metrics

The current forward P/E ratio for Zymeworks Inc (ZYME.O) is 0.00, compared to its 5-year average forward P/E of -3.71. For a more detailed relative valuation and DCF analysis to assess Zymeworks Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.71
Current PE
0.00
Overvalued PE
15.77
Undervalued PE
-23.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
5.57
Current EV/EBITDA
-0.56
Overvalued EV/EBITDA
45.03
Undervalued EV/EBITDA
-33.90

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
12.78
Current PS
9.85
Overvalued PS
27.98
Undervalued PS
-2.41

Financials

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Quarterly

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Whales Holding ZYME

A
Artal Group S.A.
Holding
ZYME
+16.63%
3M Return
P
Perceptive Advisors LLC
Holding
ZYME
+14.76%
3M Return
V
Vestal Point Capital, LP
Holding
ZYME
+12.47%
3M Return
E
EcoR1 Capital, LLC
Holding
ZYME
+9.41%
3M Return
B
BVF Partners L.P.
Holding
ZYME
+6.03%
3M Return
R
Rubric Capital Management LP
Holding
ZYME
+3.33%
3M Return

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Frequently Asked Questions

What is Zymeworks Inc (ZYME) stock price today?

The current price of ZYME is 27.85 USD — it has increased 0.18

What is Zymeworks Inc (ZYME)'s business?

Zymeworks Inc. is a biotechnology company. The Company is engaged in managing a portfolio of healthcare assets and developing a pipeline of multifunctional biotherapeutics to improve the standard of care for conditions, including cancer, inflammation, and autoimmune disease. Its antibody-drug conjugates (ADCs) include ZW191, ZW251, and ZW220. ZW191 is a clinical-stage ADC that targets folate receptor alpha-expressing tumors including ovarian cancer, endometrial cancer, and non-small cell lung cancer (NSCLC), which is built using bystander-active, TOPO1i payload technology, ZD06519. ZW251 is a clinical-stage ADC molecule designed for the treatment of glypican 3 (GPC3)-expressing hepatocellular carcinoma (HCC). ZW220 is an ADC that targets NaPi2b-expressing NSCLC and ovarian cancer, built using bystander active TOPO1i payload technology, ZD06519. Its therapeutic platforms can be used to develop multifunctional fit-for-purpose biotherapeutics with bispecific capabilities.

What is the price predicton of ZYME Stock?

Wall Street analysts forecast ZYME stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ZYME is35.55 USD with a low forecast of 30.00 USD and a high forecast of 42.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Zymeworks Inc (ZYME)'s revenue for the last quarter?

Zymeworks Inc revenue for the last quarter amounts to 27.61M USD, increased 72.59

What is Zymeworks Inc (ZYME)'s earnings per share (EPS) for the last quarter?

Zymeworks Inc. EPS for the last quarter amounts to -0.26 USD, decreased -33.33

How many employees does Zymeworks Inc (ZYME). have?

Zymeworks Inc (ZYME) has 280 emplpoyees as of April 21 2026.

What is Zymeworks Inc (ZYME) market cap?

Today ZYME has the market capitalization of 2.07B USD.