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ZYME Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
24.750
Open
24.090
VWAP
24.18
Vol
596.71K
Mkt Cap
1.80B
Low
23.590
Amount
14.43M
EV/EBITDA(TTM)
--
Total Shares
74.30M
EV
1.56B
EV/OCF(TTM)
--
P/S(TTM)
17.34
Zymeworks Inc. is a global clinical-stage biotechnology company. The Company is developing a diverse pipeline of multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases such as cancer, autoimmune and inflammatory diseases (AIID). The Company engineered and developed zanidatamab, a HER2-targeted bispecific antibody using the Company’s Azymetric technology. It has entered into separate agreements with BeiGene, Ltd. and Jazz Pharmaceuticals Ireland Limited, granting each exclusive rights to develop and commercialize zanidatamab in different territories. It is advancing a pipeline of wholly-owned product candidates, leveraging its expertise in both antibody-drug conjugates and multispecific antibody therapeutics targeting novel pathways in areas of significant unmet medical need. The Company has two clinical-stage product candidates: ZW171 and ZW191. Its preclinical product candidates include ZW251, ZW220, ZW209, and ZW1528.
Show More

Events Timeline

(ET)
2026-03-30
06:10:00
Zymeworks' ZW191 Receives FDA Fast Track Designation
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2026-03-30
06:10:00
Zymeworks Receives FDA Fast Track Designation for ZW191
select
2026-03-18 (ET)
2026-03-18
07:50:00
Zymeworks Partner Jazz Pharmaceuticals to Present Ziihera Clinical Trial Data at AACR Annual Meeting
select
2026-03-02 (ET)
2026-03-02
09:00:00
Stock Futures Drop Sharply as Geopolitical Risks Escalate
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2026-03-02
06:20:00
Zymeworks Secures $250M Funding from Royalty Pharma
select
2026-03-02
06:10:00
Zymeworks Reports Q4 Revenue of $2.5M
select
2026-01-12 (ET)
2026-01-12
06:30:00
Zymeworks Executive Changes: Mark Hollywood Promoted to COO
select

News

NASDAQ.COM
9.0
03-30NASDAQ.COM
Zymeworks' Investigational Drug ZW191 Receives FDA Fast Track Designation
  • FDA Fast Track Designation: Zymeworks' investigational drug ZW191 has received Fast Track designation from the FDA for treating advanced or metastatic platinum-resistant ovarian cancer, highlighting the program's potential to address significant unmet medical needs.
  • Clinical Trial Progress: A Phase I trial of ZW191 in patients with advanced solid tumors is currently underway, which is expected to expedite the drug development process and provide faster treatment options for patients.
  • Positive Market Reaction: Following the announcement, Zymeworks' stock price rose over 3% to $24.73 in premarket trading on Monday, indicating investor optimism regarding the drug's prospects.
  • Broad Applicability: As an antibody-drug conjugate targeting folate receptors, ZW191 shows potential for treating various tumor types, particularly benefiting approximately 75% of high-grade serous ovarian carcinoma patients, indicating its wide applicability in the treatment landscape.
NASDAQ.COM
9.0
03-30NASDAQ.COM
Zymeworks Receives FDA Fast Track Designation for ZW191
  • FDA Fast Track Designation: Zymeworks announced that its antibody-drug conjugate ZW191 has received Fast Track designation from the FDA for the treatment of advanced or metastatic platinum-resistant ovarian cancer patients, marking a significant advancement in the company's oncology portfolio.
  • Targeted Therapy Potential: ZW191 targets the folate receptor-a protein, which is expressed in various tumor types, including approximately 75% of high-grade serous ovarian carcinomas, over 50% of endometrial cancers, and about 70% of lung adenocarcinomas, indicating its broad applicability.
  • Unique Design Advantages: The design of ZW191 allows it to effectively internalize into FRa-expressing cells and release the novel proprietary payload ZD06519, which has the potential to kill tumor cells, thereby providing new treatment options for patients.
  • Clinical Trial Progress: Zymeworks is currently conducting a Phase 1 clinical study of ZW191 to assess its safety, tolerability, pharmacokinetics, and preliminary anti-tumor activity, which will inform future development strategies based on the data collected.
Newsfilter
9.0
03-30Newsfilter
ZW191 Receives FDA Fast Track Designation for Ovarian Cancer Treatment
  • FDA Fast Track Designation: ZW191, an antibody-drug conjugate, has received Fast Track designation from the FDA for treating advanced or metastatic platinum-resistant ovarian cancer, highlighting its potential to address significant unmet medical needs.
  • Clinical Trial Progress: Currently, ZW191 is undergoing a Phase 1 clinical trial enrolling patients with advanced solid tumors to evaluate safety, tolerability, pharmacokinetics, and preliminary anti-tumor activity, aiming to inform future development strategies with robust data.
  • Targeted Treatment Advantage: The folate receptor α targeted by ZW191 is expressed in various tumor types, including approximately 75% of high-grade serous ovarian carcinomas, indicating its potential to benefit a broad patient population without the need for biomarker selection.
  • Strengthened Company Strategy: This designation further reinforces Zymeworks' expertise in ADC development, expected to accelerate the advancement of ZW191 and enhance the company's competitive position in the oncology market.
Benzinga
9.5
03-09Benzinga
BETA Technologies Reports Disappointing Q4 Results
  • Earnings Miss: BETA Technologies reported a Q4 loss of $2.02 per share, significantly worse than the analyst consensus estimate of a loss of $0.84, indicating substantial challenges in profitability that could undermine investor confidence.
  • Sales Beat: Despite the significant losses, the company achieved quarterly sales of $11.133 million, surpassing the analyst consensus of $7.859 million, suggesting some resilience in market demand that could lay the groundwork for future growth.
  • Stock Reaction: In pre-market trading, BETA's shares fell 3.1% to $18.67, reflecting a negative investor response to the earnings report, which may lead to increased liquidity pressure in the short term.
  • Market Sentiment: The overall market sentiment is bearish, with Dow futures down over 1%, indicating investor concerns about the economic outlook, which could further impact BETA Technologies and other related stocks.
Benzinga
8.5
03-09Benzinga
Lisata Therapeutics to be Taken Private by Kuva Labs
  • Acquisition Agreement: Lisata Therapeutics Inc has agreed to be taken private by Kuva Labs, offering shareholders $5.00 per share along with a $1.00 contingent value right per share, indicating recognition of the company's future potential.
  • Significant Stock Surge: Following the acquisition announcement, Lisata Therapeutics' shares rose 20.3% in pre-market trading to $5.03, reflecting positive market reaction and increased investor confidence in the deal.
  • Impact of Privatization: The acquisition will result in Lisata Therapeutics delisting from public markets, potentially providing the company with greater flexibility to focus on long-term strategic goals while mitigating the impact of market volatility on its operations.
  • Market Dynamics Shift: The announcement of this deal has sparked interest in other related stocks, demonstrating investor enthusiasm for M&A activity in the biotech sector, which may influence future investment decisions and market trends.
moomoo
5.0
03-07moomoo
Zymeworks (ZYME.US) Insider Plans to Sell $6.13 Million Worth of Common Stock via Form 144
  • Stock Sale Announcement: Jeffery T.L.S. Smith plans to sell 247.33k shares of Zymeworks (ZYME.US) on March 6, with an estimated market value of around $6.13 million.

  • Reduction in Holdings: Since January 5, 2026, Smith has reduced his shareholding in Zymeworks by 19,848 shares, valued at approximately $475.56k.

Wall Street analysts forecast ZYME stock price to rise
14 Analyst Rating
Wall Street analysts forecast ZYME stock price to rise
14 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
35.55
High
42.00
Current: 0.000
sliders
Low
30.00
Averages
35.55
High
42.00
Evercore ISI
Outperform
maintain
$33 -> $48
AI Analysis
2026-03-09
Reason
Evercore ISI
Price Target
$33 -> $48
AI Analysis
2026-03-09
maintain
Outperform
Reason
Evercore ISI raised the firm's price target on Zymeworks (ZYME) to $48 from $33 and keeps an Outperform rating on the shares. The $250M debt deal with Royalty Pharma (RPRX) is "a smart move," providing significant optionality and the terms are "favorable," allowing Zymeworks to retain upside while strengthening its balance sheet, the analyst tells investors.
H.C. Wainwright
Buy
maintain
$32 -> $46
2026-03-06
Reason
H.C. Wainwright
Price Target
$32 -> $46
2026-03-06
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on Zymeworks to $46 from $32 and keeps a Buy rating on the shares post the Q4 report. The firm cites the company's shift towards a more royalty-focused strategy for the target boost.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ZYME
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Valuation Metrics

The current forward P/E ratio for Zymeworks Inc (ZYME.O) is -28.70, compared to its 5-year average forward P/E of -3.76. For a more detailed relative valuation and DCF analysis to assess Zymeworks Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.76
Current PE
-28.70
Overvalued PE
15.62
Undervalued PE
-23.14

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
6.56
Current EV/EBITDA
216.60
Overvalued EV/EBITDA
47.29
Undervalued EV/EBITDA
-34.16

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
13.30
Current PS
20.84
Overvalued PS
29.04
Undervalued PS
-2.44

Financials

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Quarterly

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Whales Holding ZYME

A
Artal Group S.A.
Holding
ZYME
+1.99%
3M Return
V
Vestal Point Capital, LP
Holding
ZYME
+1.52%
3M Return
P
Perceptive Advisors LLC
Holding
ZYME
-0.51%
3M Return
R
Rubric Capital Management LP
Holding
ZYME
-1.10%
3M Return
E
EcoR1 Capital, LLC
Holding
ZYME
-1.35%
3M Return
B
BVF Partners L.P.
Holding
ZYME
-2.32%
3M Return

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Frequently Asked Questions

What is Zymeworks Inc (ZYME) stock price today?

The current price of ZYME is 24.21 USD — it has increased 0.12

What is Zymeworks Inc (ZYME)'s business?

Zymeworks Inc. is a global clinical-stage biotechnology company. The Company is developing a diverse pipeline of multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases such as cancer, autoimmune and inflammatory diseases (AIID). The Company engineered and developed zanidatamab, a HER2-targeted bispecific antibody using the Company’s Azymetric technology. It has entered into separate agreements with BeiGene, Ltd. and Jazz Pharmaceuticals Ireland Limited, granting each exclusive rights to develop and commercialize zanidatamab in different territories. It is advancing a pipeline of wholly-owned product candidates, leveraging its expertise in both antibody-drug conjugates and multispecific antibody therapeutics targeting novel pathways in areas of significant unmet medical need. The Company has two clinical-stage product candidates: ZW171 and ZW191. Its preclinical product candidates include ZW251, ZW220, ZW209, and ZW1528.

What is the price predicton of ZYME Stock?

Wall Street analysts forecast ZYME stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ZYME is35.55 USD with a low forecast of 30.00 USD and a high forecast of 42.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Zymeworks Inc (ZYME)'s revenue for the last quarter?

Zymeworks Inc revenue for the last quarter amounts to 27.61M USD, increased 72.59

What is Zymeworks Inc (ZYME)'s earnings per share (EPS) for the last quarter?

Zymeworks Inc. EPS for the last quarter amounts to -0.26 USD, decreased -33.33

How many employees does Zymeworks Inc (ZYME). have?

Zymeworks Inc (ZYME) has 280 emplpoyees as of March 31 2026.

What is Zymeworks Inc (ZYME) market cap?

Today ZYME has the market capitalization of 1.80B USD.