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ZYME Earnings

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Earning Analysis

Welcome to our in-depth analysis of Zymeworks Inc(ZYME) earnings, offering investors a detailed look into the company’s financial performance, revenue trends, earnings per share (EPS), and market reactions. This page provides a comprehensive overview of Zymeworks Inc earnings history, forecasts, and key financial metrics, empowering you with the data needed to make informed investment decisions. Whether you're tracking quarterly results, analyzing earnings surprises, or exploring future projections, our detailed breakdown covers it all.

Earnings Forecast

Revenue
EPS
Currency: USD
Actual
Estimate

Surprise Analysis

Name
EPS
Revenue
Price Reaction
Fiscal QuarterEarning DateTimeEstimateActualSurprise%EstimateActualSurprise%1D5D
Fiscal Quarter
Earning Date
Time
Estimate
Actual
Surprise%
Estimate
Actual
Surprise%
1D
5D
FY2025Q32025-11-06After Hours-0.30-0.26+13.3329.91M27.61M-7.67-8.04+8.21
FY2025Q22025-08-07After Hours-0.520.03+105.7716.88M48.73M+188.75-1.15+14.64
FY2025Q12025-05-08After Hours-0.45-0.30+33.3320.65M27.11M+31.26-0.13-0.62
FY2024Q42025-03-05After Hours-0.32-0.31+3.1345.20M31.03M-31.34-7.97-6.83
FY2024Q32024-10-31After Hours-0.40-0.39+2.5017.85M16.00M-10.38-3.07+22.41
FY2024Q22024-08-01--0.27-0.26+3.7020.12M19.24M-4.37-3.35-6.02
FY2024Q12024-05-02--0.31-0.42-35.4816.65M10.03M-39.77+2.74+3.42
FY2023Q42024-03-06--0.39-0.20+48.7217.66M16.93M-4.18+2.09-9.77
FY2023Q32023-11-07--0.55-0.41+25.4514.43M16.51M+14.37+1.24-0.14
FY2023Q22023-08-10--0.51-0.76-49.0216.97M7.00M-58.73+0.78-5.58
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ZYME Earnings Analysis

Our earnings analysis provides a granular look at the company’s performance across recent fiscal quarters, highlighting key metrics such as revenue, EPS, and operating margins. By examining actual results against analyst estimates, we uncover trends and surprises that drive stock price movements, offering valuable insights for both short-term traders and long-term investors.
In the most recent quarter, Zymeworks Inc reported performance for FY2025Q3, announced on 2025-11-06. The company achieved an EPS of -0.26, compared to analyst estimates of -0.30 by 13.33% . Revenue for the quarter reached 27.61M compared to expectations of 29.91M by -7.67% .
The stock price reacted with a -8.04% one-day change and a 8.21% five-day change following the earnings release. These movements reflect market reaction in Zymeworks Inc growth trajectory and strategic initiatives.

ZYME Earnings Forecast

Looking ahead, Zymeworks Inc(ZYME) remains a focal point for investors seeking growth opportunities. Analyst forecasts for 2025/Q4 project quarter revenue of 20.32M and an EPS of -0.34.
However, recent estimate revisions provide additional context. Over the past three months, revenue estimates for FY2025 have been Revise Downward by -18.03%, while EPS estimates have been Revise Upward by 30.84%. For the upcoming Q4 2025, revenue estimates have been adjusted Revise Downward by -63.38% . These revisions correlate with a 76.21% change in stock price over the same period, suggesting potential buying opportunities for investors who believe in Zymeworks Inc long-term fundamentals.
The relationship between earnings forecast revisions and stock price movements is critical for investors. Positive revisions in revenue or EPS often signal strengthening fundamentals, making temporary price dips attractive entry points. Conversely, downward revisions may reflect short-term challenges.

Estimate Revision

The chart shows the correlation between ZYME's stock price and earnings forecast revisions. Positive revisions in Revenue or EPS often strengthen the stock's fundamentals, making price dips potential buying opportunities.
Revenue Estimates for FY2025
Revise Downward
down Image
-18.03%
In Past 3 Month
EPS Estimates for FY2025
Revise Upward
up Image
+30.84%
In Past 3 Month
Revenue Estimates for Q4 2025
Revise Downward
down Image
-63.38%
In Past 3 Month
Stock Price
Go Up
up Image
+76.21%
In Past 3 Month
1Y
3Y
5Y
Annual FY 2025
Currency: USD
Currency: USD
1Y
3Y
5Y
--
Revenue Estimate-Annual FY 2025:120.43M
--
EPS Estimate-Annual FY 2025:-1.02
—
Stock Price26.52
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ZYME Revenue and EPS Performance: A Historical Perspective

Zymeworks Inc revenue and earnings per share (EPS) performance over recent quarters provides a clear picture of its financial health. Below is a detailed breakdown of the company’s earnings history, showcasing actual results, analyst estimates, and surprise percentages for key fiscal quarters:
FY2025Q3 (2025-11-06,After Hours):
EPS: -0.26 (Actual) vs.-0.30 (Estimate) (13.33%)
Revenue: 27.61M (Actual) vs. 29.91M (Estimate) (-7.67%)
Price Reaction: -8.04%(1-Day), 8.21%(5-Day)
FY2025Q2 (2025-08-07,After Hours):
EPS: 0.03 (Actual) vs.-0.52 (Estimate) (105.77%)
Revenue: 48.73M (Actual) vs. 16.88M (Estimate) (188.75%)
Price Reaction: -1.15%(1-Day), 14.64%(5-Day)
FY2025Q1 (2025-05-08,After Hours):
EPS: -0.30 (Actual) vs.-0.45 (Estimate) (33.33%)
Revenue: 27.11M (Actual) vs. 20.65M (Estimate) (31.26%)
Price Reaction: -0.13%(1-Day), -0.62%(5-Day)
Earnings Reaction
The chart below shows how ZYME performed 10 days before and after its earnings report, based on data from the past quarters. Typically, ZYME sees a +1.21% change in stock price 10 days leading up to the earnings, and a +7.48% change 10 days following the report. On the earnings day itself, the stock moves by +0.26%. This data can give you a slight idea of what to expect for the next quarter's release.
For example, in SEP/2025, the stock changed -8.04% on the day following the earnings release and then changed by 33.07% over the next 10 days. These patterns provide investors with valuable insights into potential price movements and help inform trading strategies around earnings events.
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Transcript Summary

Zymeworks Inc (ZYME) Q3 2025 Earnings Call Summary
Neutral
2025-11-06
The earnings call reveals mixed signals: a net income increase, but decreased cash reserves. Positive updates include regulatory approvals and promising drug trials. However, management's vague responses in the Q&A, particularly on PFS analysis and third-party milestones, raise concerns. The absence of guidance changes and reliance on future milestones temper optimism. Consequently, the stock reaction is predicted to be neutral.
Zymeworks Inc (ZYME) Q2 2025 Earnings Call Summary
Positive
2025-08-08
The earnings call summary indicates strong financial performance with a net income of $2.3 million compared to a loss in the previous year, revenue growth, and increased cash resources. The Q&A section reveals management's confidence in their pipeline and operational strategies, despite some unclear responses. The absence of significant negative trends or risks, along with optimistic guidance and strategic partnerships, supports a positive outlook for the stock price in the short term.
Zymeworks Inc (ZYME) Q1 2025 Earnings Call Summary
Neutral
2025-05-10
The earnings call summary presents a mixed picture: EPS beat expectations, indicating operational efficiency, but the absence of shareholder return plans and the inherent risks in a competitive biotech environment temper enthusiasm. The Q&A reveals management's cautious optimism and avoidance of specifics in some areas, which may raise concerns. Although financial metrics improved, guidance remains uncertain, leading to a neutral sentiment. Given the lack of market cap data, it's prudent to assume a moderate market reaction, resulting in a stock price movement prediction in the neutral range (-2% to 2%).
Zymeworks Inc (ZYME) Q1 2025 Earnings Call Summary
Positive
2025-05-08
The earnings call highlights strong financial performance with a 171% revenue increase and reduced net loss, indicating improved financial health. Strategic partnerships with leading pharma companies, ongoing clinical trials, and a promising pipeline further support a positive outlook. However, management's reluctance to provide guidance on certain programs introduces some uncertainty. Overall, the positive financial performance, strong partnerships, and pipeline advancements outweigh the uncertainties, suggesting a positive stock price movement over the next two weeks.
Zymeworks Inc (ZYME) Q4 2024 Earnings Call Summary
Negative
2025-03-06
The earnings call reveals disappointing financial results, with a significant EPS miss and increased net loss. Despite optimistic guidance and strategic prioritization of ZW251, management's unclear responses on trial delays raise concerns. The cash burn and decreased cash resources further weigh on sentiment. While share repurchases and potential milestone payments offer some positives, they are overshadowed by the financial performance and uncertainties, leading to a likely negative market reaction.
Zymeworks Inc (ZYME) Q4 2024 Earnings Call Summary
Neutral
2025-03-05
The earnings call summary presents a mixed outlook. Financial performance shows some positive aspects, such as milestone revenues and reduced net loss. However, cash resources have declined, and management avoided giving clear guidance on key projects, raising concerns. The Q&A session highlighted management's reluctance to provide specifics on delays and future milestones, which may cause uncertainty among investors. The share repurchase program is a positive factor, but overall, the lack of clear guidance and financial uncertainties suggest a neutral stock price reaction in the short term.
Zymeworks Inc. (ZYME) Q3 2024 Earnings Call Summary
Negative
2024-11-01
The earnings call summary reveals a mixed outlook. While there is a decrease in net loss and operating expenses, the decline in revenue and cash resources raises concerns about financial sustainability. The Q&A section highlights uncertainties around clinical trials and management's reluctance to provide specific timelines. The completion of the first tranche of the share repurchase program is a positive, but the lack of guidance on future buybacks and reliance on partnerships add to the negative sentiment. Overall, the financial and strategic uncertainties suggest a negative stock price reaction.
Zymeworks Inc. (ZYME) Q2 2024 Earnings Call Summary
Negative
2024-08-02
The earnings call summary indicates several negative factors: a significant revenue decline, impairment charges, and competitive pressures. Despite a share repurchase program, financial performance remains weak with a net loss and cash decrease. The Q&A section reveals management's lack of transparency on critical clinical trial details, adding uncertainty. While the share repurchase program suggests confidence, the overall sentiment is negative due to financial challenges, competitive risks, and management's evasiveness in addressing key concerns.

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FAQ

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What were the key highlights of ZYME’s latest earnings report for FY2025Q3?

ZYME reported its FY2025Q3 earnings on 2025-11-06, showcasing a revenue of 27.61M against an estimate of 29.91M, resulting in a -7.67% surprise. The EPS was -0.26, surpassing the expected -0.3 by 13.33% . The stock experienced a -8.04% price change on the earnings day and a 8.21% change over the next five days, reflecting market reactions to the results.
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How did ZYME’s stock price react after the FY2025Q3 earnings release?

Following ZYME’s FY2025Q3 earnings announcement on 2025-11-06, the stock price moved by -8.04% on the day of the release. Over the subsequent five days, it saw a 8.21% change. Historically, ZYME’s stock price tends to shift by an average of +1.21% in the 10 days leading up to earnings and +7.48% in the 10 days following, providing insight into potential market.
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What are the revenue and EPS estimates for ZYME for 2025/Q4?

For 2025/Q4, analysts estimate ZYME’s annual revenue to reach 20.32M, while the EPS is projected at -0.34. These estimates reflect recent revisions, with revenue estimates revised Revenue Revise Downward by -18.03% and EPS estimates Revise Downward by -63.38% over the past three months, indicating analyst expectation in the company’s performance.
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How does ZYME’s stock price correlate with earnings forecast revisions?

The correlation between ZYME’s stock price and earnings forecast revisions shows that positive revisions in revenue or EPS often strengthen the stock’s fundamentals. Over the past three months, revenue estimates for FY2025 were Revise Downward by -18.03%, while EPS estimates moved Revise Downward by -63.38% . This trend suggests that price dips could present buying opportunities for investors.
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What should investors expect from ZYME’s next earnings report?

Based on historical trends, ZYME’s stock price typically moves by +1.21% in the 10 days before its earnings and +7.48% in the 10 days after. For the upcoming 2025/Q4 earnings, analysts expect an EPS of -0.34 and revenue of 20.32M.
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What is the sentiment in Zymeworks Inc (ZYME) Q3 2025 Earnings Call Summary?

The earnings call reveals mixed signals: a net income increase, but decreased cash reserves. Positive updates include regulatory approvals and promising drug trials. However, management's vague responses in the Q&A, particularly on PFS analysis and third-party milestones, raise concerns. The absence of guidance changes and reliance on future milestones temper optimism. Consequently, the stock reaction is predicted to be neutral.
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