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ORKA Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
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Intellectia

Loading chart...

High
36.180
Open
33.500
VWAP
34.63
Vol
326.40K
Mkt Cap
1.63B
Low
33.330
Amount
11.30M
EV/EBITDA(TTM)
--
Total Shares
48.41M
EV
1.28B
EV/OCF(TTM)
--
P/S(TTM)
--
Oruka Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its lead program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, psoriatic arthritis (PsA), and other conditions. ORKA-001 is an extended half-life monoclonal antibody (mAb) designed to target IL-23p19. IL-23 is a pro-inflammatory cytokine that plays a critical role in the proliferation and development of T helper 17 (Th17) cells, which are the primary drivers of several autoimmune and inflammatory disorders, including PsO. IL-23 is composed of two subunits: a p40 subunit and a p19 subunit. ORKA-002 is an extended half-life mAb designed to target IL-17A and IL-17F (IL-17A/F).
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Events Timeline

(ET)
2026-01-12
07:20:00
Oruka Therapeutics Reports Positive Interim Data from ORKA-002 Phase 1 Trial
select
2025-11-12 (ET)
2025-11-12
17:01:53
Oruka Therapeutics announces Q3 earnings per share of 55 cents, surpassing consensus estimate of 52 cents.
select

News

NASDAQ.COM
8.0
01-09NASDAQ.COM
Five Below Options Volume Hits 7,969 Contracts, 71.5% of Daily Average
  • Active Options Trading: Five Below Inc's options volume reached 7,969 contracts today, equivalent to approximately 796,900 shares, indicating significant market activity and representing 71.5% of its average daily trading volume of 1.1 million shares over the past month.
  • High Demand Options: Notably, the $220 strike call option expiring on January 16, 2026, saw 1,886 contracts traded today, representing about 188,600 shares, reflecting strong market interest at this price level.
  • PureCycle Trading Activity: Concurrently, PureCycle Technologies Inc experienced options trading volume of 27,453 contracts, equivalent to approximately 2.7 million shares, which is about 71.3% of its average daily trading volume of 3.9 million shares over the past month, indicating investor attention on this stock as well.
  • Put Option Activity: Within PureCycle, the $11 strike put option expiring on March 20, 2026, saw 3,979 contracts traded today, representing approximately 397,900 shares, reflecting a cautious market sentiment regarding the stock's future performance.
Globenewswire
1.0
01-06Globenewswire
Oruka to Present Novel Biologics at 44th Annual J.P. Morgan Healthcare Conference
  • Conference Presentation: Oruka Therapeutics will present at the 44th Annual J.P. Morgan Healthcare Conference on January 15, 2026, which is expected to attract attention from investors and industry experts, thereby enhancing the company's visibility in the biologics sector.
  • Innovative Treatment: Oruka is developing novel biologics targeting chronic skin diseases like plaque psoriasis, aiming for high rates of complete disease clearance with dosing as infrequently as once or twice a year, significantly improving patients' quality of life.
  • Technological Advantage: The biologics are engineered by Paragon Therapeutics to target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases, showcasing the company's R&D strength and market potential in biotechnology.
  • Investor Relations: Oruka will provide a webcast and replay of the presentation on its investor events website, enhancing engagement with investors and increasing transparency to attract more attention to its innovative products.
NASDAQ.COM
4.5
2025-12-31NASDAQ.COM
Sprott Silver Miners ETF Declines 2.3% with Americas Gold and Vizsla Silver Underperforming
  • ETF Performance Decline: The Sprott Silver Miners & Physical Silver ETF fell approximately 2.3% in Wednesday afternoon trading, reflecting a weak sentiment towards silver mining stocks that could impact investor confidence.
  • Individual Stock Weakness: Shares of Americas Gold and Silver dropped about 2.8%, while Vizsla Silver declined by approximately 1.6%, indicating the vulnerability of these companies in the current market environment, potentially leading to capital outflows.
  • Market Trend Analysis: The overall decline of the ETF is linked to fluctuations in silver prices and investor risk aversion towards mining stocks, which may influence future investment decisions and capital allocation.
  • Investor Focus: As silver mining stocks continue to struggle, investors may need to reassess their allocations within precious metal portfolios to mitigate potential market risks.
Benzinga
4.0
2025-11-13Benzinga
Gilead Sciences Analyst Starts Coverage Optimistically; Check Out the Top 5 Initiations for Thursday
  • Analyst Coverage Initiations: BMO Capital initiated coverage on Veeva Systems with a Market Perform rating and a price target of $300, while Scotiabank rated Gilead Sciences as Sector Outperform with a target of $140.

  • Buy Ratings Issued: Roth Capital initiated coverage on CPS Technologies with a Buy rating and a price target of $6, and Jefferies rated Oruka Therapeutics with a Buy and a target of $45.

  • CoreWeave Rating: Compass Point initiated coverage on CoreWeave with a Buy rating and a price target of $150, reflecting positive sentiment towards the stock.

  • Current Stock Prices: As of Wednesday, Veeva closed at $296.96, Gilead at $123.40, CPS Technologies at $3.30, Oruka Therapeutics at $28.30, and CoreWeave at $85.43.

Benzinga
6.0
2025-11-13Benzinga
AutoZone Set to Surge Over 12%? Check Out 10 Leading Analyst Predictions for Thursday
  • Analyst Upgrades: Goldman Sachs upgraded AutoZone Inc. from Neutral to Buy, raising its price target from $4,090 to $4,262, while also increasing On Holding AG's target from $50 to $52, maintaining a Neutral rating.

  • Analyst Downgrades: Deutsche Bank cut Circle Internet Group Inc.'s price target from $147 to $90, maintaining a Hold rating, and Goldman Sachs downgraded Dollar Tree Inc. from Buy to Sell, lowering its target from $133 to $103.

  • Price Target Adjustments: Morgan Stanley raised Cisco Systems Inc.'s price target from $77 to $82, while B of A Securities increased FedEx Corp.'s target from $270 to $285, both maintaining their respective ratings.

  • Mixed Ratings: BTIG cut Flutter Entertainment PLC's price target from $321 to $271 but maintained a Buy rating, while HC Wainwright & Co. reduced Largo Inc.'s target from $3.7 to $2.9, also keeping a Buy rating.

Benzinga
4.0
2025-11-13Benzinga
BTIG Reaffirms Buy Rating for Oruka Therapeutics and Increases Price Target to $63
  • Fastest News Alerts: Benzinga Pro offers real-time intelligence to help traders stay updated and make informed decisions in the stock market.

  • Exclusive Stories: The platform provides unique stories and insights generated by Benzinga reporters, enhancing the trading experience for its users.

  • Community of Traders: Over 10,000 serious traders are part of the Benzinga Pro community, sharing knowledge and strategies.

  • Market Intelligence: Users can access the most accurate stock market intelligence to improve their trading outcomes.

Wall Street analysts forecast ORKA stock price to rise
10 Analyst Rating
Wall Street analysts forecast ORKA stock price to rise
10 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
40.00
Averages
51.67
High
75.00
Current: 0.000
sliders
Low
40.00
Averages
51.67
High
75.00
Clear Street
Kaveri Pohlman
Buy
maintain
$71
AI Analysis
2026-02-04
Reason
Clear Street
Kaveri Pohlman
Price Target
$71
AI Analysis
2026-02-04
maintain
Buy
Reason
Clear Street analyst Kaveri Pohlman believes AbbVie's (ABBV) plan to bring an extended half-life anti-IL-23 mAb into the clinic this year further validates Oruka Therapeutics' (ORKA) strategy. Together with Rapt Therapeutics' (RAPT) recent $2.2B takeout by GSK (GSK) for a half-life-extended Xolair analog, these moves reinforce the view that convenience-oriented drugs are becoming preferred development bets in I&I-and potentially even in oncology, Clear Street argues. The firm further states that Oruka's IL-23 lead and ORKA-002 rights provide structural edge, making competition less of a concern, Clear Street reiterates a Buy rating on Oruka with a price target of $71.
UBS
Buy
initiated
$50
2026-01-07
Reason
UBS
Price Target
$50
2026-01-07
initiated
Buy
Reason
UBS initiated coverage of Oruka Therapeutics (ORKA) with a Buy rating and $50 price target as the analyst initiated or assumed coverage on 22 small-to-mid cap biotech names. After a rough period, biotech fundamentals are now inflecting, contends the analyst, who expects investor confidence to recover and sees this positioning biotech for strong performance in 2026. Among the group, top picks include Apogee Therapeutics (APGE), Cogent Biosciences (COGT), Kodiak Sciences (KOD), Ideaya Biosciences (IDYA), Inventiva (IVA), SAB Biotherapeutics (SABS) and Ventyx Biosciences (VTYX), which the analyst highlights as having key upcoming catalysts, de-risked best-in-class portfolios, strong data, and broader pipelines.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ORKA
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Valuation Metrics

The current forward P/E ratio for Oruka Therapeutics Inc (ORKA.O) is -10.68, compared to its 5-year average forward P/E of -6.99. For a more detailed relative valuation and DCF analysis to assess Oruka Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.99
Current PE
-10.68
Overvalued PE
-4.39
Undervalued PE
-9.59

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding ORKA

P
Paradigm Biocapital Advisors LP
Holding
ORKA
+9.28%
3M Return
C
Commodore Capital LP
Holding
ORKA
+6.85%
3M Return
P
Perceptive Advisors LLC
Holding
ORKA
+6.14%
3M Return
V
VR Management, LLC
Holding
ORKA
+6.00%
3M Return
F
Fairmount Funds Management LLC
Holding
ORKA
+5.89%
3M Return
C
Cormorant Asset Management, LP
Holding
ORKA
+0.42%
3M Return

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Frequently Asked Questions

What is Oruka Therapeutics Inc (ORKA) stock price today?

The current price of ORKA is 34.385 USD — it has increased 2.06

What is Oruka Therapeutics Inc (ORKA)'s business?

Oruka Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its lead program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, psoriatic arthritis (PsA), and other conditions. ORKA-001 is an extended half-life monoclonal antibody (mAb) designed to target IL-23p19. IL-23 is a pro-inflammatory cytokine that plays a critical role in the proliferation and development of T helper 17 (Th17) cells, which are the primary drivers of several autoimmune and inflammatory disorders, including PsO. IL-23 is composed of two subunits: a p40 subunit and a p19 subunit. ORKA-002 is an extended half-life mAb designed to target IL-17A and IL-17F (IL-17A/F).

What is the price predicton of ORKA Stock?

Wall Street analysts forecast ORKA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ORKA is51.67 USD with a low forecast of 40.00 USD and a high forecast of 75.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Oruka Therapeutics Inc (ORKA)'s revenue for the last quarter?

Oruka Therapeutics Inc revenue for the last quarter amounts to -34.10M USD, increased 15.81

What is Oruka Therapeutics Inc (ORKA)'s earnings per share (EPS) for the last quarter?

Oruka Therapeutics Inc. EPS for the last quarter amounts to -21701000.00 USD, decreased -38.05

How many employees does Oruka Therapeutics Inc (ORKA). have?

Oruka Therapeutics Inc (ORKA) has 28 emplpoyees as of March 11 2026.

What is Oruka Therapeutics Inc (ORKA) market cap?

Today ORKA has the market capitalization of 1.63B USD.