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SMMT Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
19.005
Open
17.300
VWAP
18.39
Vol
3.94M
Mkt Cap
14.70B
Low
17.200
Amount
72.36M
EV/EBITDA(TTM)
--
Total Shares
775.37M
EV
12.45B
EV/OCF(TTM)
--
P/S(TTM)
--
Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial.
Show More

Events Timeline

(ET)
2026-03-27
11:40:00
Biotech Stocks Surge in Search Activity, Radiopharm Up 2566.66%
select
2026-02-23 (ET)
2026-02-23
16:20:00
HARMONi-3 Clinical Trial Progress Update
select
2026-01-29 (ET)
2026-01-29
07:40:00
Summit Therapeutics Files Biologics License Application for Ivonescimab
select

News

CNBC
6.5
03-31CNBC
Citi Identifies Stocks with Upside Amid U.S.-Iran Conflict
  • Market Turmoil Impact: The ongoing U.S.-Iran conflict has caused concern among investors, leading to a nearly 8% drop in the S&P 500 in March, marking its worst monthly performance since 2022.
  • Citi Analyst Strategy: Citi analyst Richard Schlatter sought stocks that could sidestep recent volatility by overlaying crowding composites tracked by Citi, identifying stocks with positive catalysts that are not relatively crowded, aiming for a favorable reaction to fundamental tailwinds.
  • Delta Air Lines Outlook: Delta Air Lines' stock has only dropped 3.8% this month, despite a nearly 9% decline in 2026, with Wall Street expecting a rebound; the average analyst price target from LSEG suggests a potential 25% gain over the next year.
  • Summit Therapeutics Performance: Summit Therapeutics' stock has risen 2.4% since the war began, with a long crowding composite of just 18.1%, and analysts are generally bullish, as 13 out of 18 covering analysts rate it a buy or strong buy.
Newsfilter
9.0
03-27Newsfilter
Summit Presents Updated Ivonescimab Data at ELCC 2026
  • Clinical Data Update: Summit Therapeutics will present updated data on ivonescimab at the 2026 European Lung Cancer Congress, covering intracranial anti-tumor activity from the global HARMONi Phase III study, which is expected to attract industry attention and enhance the company's reputation in cancer immunotherapy.
  • Improved Intracranial Survival: In the HARMONi study, patients receiving ivonescimab plus chemotherapy showed an intracranial progression-free survival (PFS) of 10.1 months compared to 6.5 months for chemotherapy alone, indicating the potential advantage of this therapy in EGFR-mutated non-small cell lung cancer (NSCLC) patients.
  • Quality of Life Assessment: The second poster will showcase health-related quality of life data comparing ivonescimab with placebo plus chemotherapy, emphasizing the drug's potential to improve patient quality of life, which may enhance market recognition.
  • Multiple Ongoing Trials: Ivonescimab is currently involved in over 15 Phase III clinical trials globally, covering various cancer types, indicating the company's extensive positioning in cancer treatment and future growth potential.
Yahoo Finance
4.0
03-26Yahoo Finance
Jefferies Downgrades Summit Therapeutics with Target Price Cut
  • Rating Downgrade: Jefferies downgraded Summit Therapeutics from Buy to Hold, reflecting a cautious market outlook on the company's future performance amid uncertainties.
  • Target Price Revision: The target price was significantly cut from $42 to $15, indicating a reassessment of the company's growth potential, which may impact investor confidence and lead to stock price volatility.
  • Clinical Trial Progress: Summit completed screening for the squamous cohort in Q1 2026, with enrollment for the non-squamous cohort expected to finish in the second half of the year, potentially supporting future treatment options for the company.
  • Financial Performance: The company reported an adjusted EPS of -$0.14 for Q4, exceeding the market consensus of -$0.01, demonstrating operational resilience despite a challenging overall market environment.
Fool
8.5
03-25Fool
Summit Therapeutics Faces FDA Review Risk for Ivonescimab
  • Regulatory Application Progress: Summit Therapeutics has filed for FDA approval of ivonescimab, which is already approved in China; however, survival data from Western countries has not shown statistical significance, potentially jeopardizing its marketing authorization.
  • Market Valuation Changes: Currently, Summit's market cap stands at $12 billion, approximately 48% higher than Axsome and 17% higher than Madrigal, but if the FDA declines ivonescimab, the stock could face a drop of over 20%.
  • Competitor Dynamics: Axsome Therapeutics and Madrigal Pharmaceuticals reported revenue growth of 65.5% and 432% in 2025, respectively, indicating strong market potential that could see them surpass Summit in the near future.
  • Investor Risk Assessment: While Summit has long-term potential in oncology, its short-term outlook is uncertain, prompting investors to carefully evaluate risks, especially in light of possible negative clinical trial outcomes.
NASDAQ.COM
8.5
03-25NASDAQ.COM
Summit Therapeutics Faces FDA Approval Risk for Ivonescimab
  • FDA Approval Crucial: Summit Therapeutics has filed for FDA approval of ivonescimab, which is already approved in China; however, the drug has not shown statistically significant overall survival in Western countries, and a rejection could lead to a significant drop in stock price.
  • Intensifying Market Competition: Axsome Therapeutics and Madrigal Pharmaceuticals have market caps of $8.1 billion and $10.2 billion respectively, with both companies poised to potentially surpass Summit by 2026, highlighting the fierce competition in the biotech sector.
  • Axsome's Growth Momentum: Axsome Therapeutics reported a 65.5% revenue increase in 2025, reaching $638.5 million, and is awaiting FDA approval for its Alzheimer's drug AXS-05, which could significantly expand its market reach.
  • Madrigal's Sales Surge: Madrigal Pharmaceuticals achieved $958.4 million in sales from its Rezdiffra drug in 2025, a 432% increase from 2024, indicating strong growth potential in the metabolic dysfunction space, with expectations for continued excellent financial performance.
Barron's
4.5
03-25Barron's
U.S. Markets Increased on Wednesday; Summit Therapeutics Led the Way
  • U.S. Stock Market Performance: U.S. stock indexes experienced gains on Wednesday, with the S&P 500 rising by 0.77%.
  • Index Increases: The Dow Jones Industrial Average increased by 0.66%, while the Nasdaq Composite saw a rise of 0.54%.
Wall Street analysts forecast SMMT stock price to rise
12 Analyst Rating
Wall Street analysts forecast SMMT stock price to rise
8 Buy
3 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
18.00
Averages
42.49
High
131.90
Current: 0.000
sliders
Low
18.00
Averages
42.49
High
131.90
Jefferies
Buy
to
Hold
downgrade
$42 -> $15
AI Analysis
2026-03-16
Reason
Jefferies
Price Target
$42 -> $15
AI Analysis
2026-03-16
downgrade
Buy
to
Hold
Reason
Jefferies downgraded Summit Therapeutics to Hold from Buy with a price target of $15, down from $42, after assuming coverage of the name. Summit has four major catalysts in 2026, and each has risk, the analyst tells investors in a research note. The firm believes a "clean win is not an easy call" for the HARMONi-6 readout given the uncertain China-to-global translation. While PD-1/VEGF is a promising class and Summit is the early mover, Jefferies would look for another way to play it.
Citi
Yigal Nochomovitz
Buy
maintain
$40
2026-02-24
Reason
Citi
Yigal Nochomovitz
Price Target
$40
2026-02-24
maintain
Buy
Reason
Citi analyst Yigal Nochomovitz placed an "upside 90-day catalyst watch" on shares of Summit Therapeutics while keeping a Buy rating on the name with a $40 price target. The company's HARMONi-3 squamous cohort date in Q2 could "revitalize the stock" and bring a path to "rapid engagement" with the FDA, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SMMT
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Valuation Metrics

The current forward P/E ratio for Summit Therapeutics Inc (SMMT.O) is -51.56, compared to its 5-year average forward P/E of -21.65. For a more detailed relative valuation and DCF analysis to assess Summit Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-21.65
Current PE
-51.56
Overvalued PE
5.17
Undervalued PE
-48.47

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-15.33
Current EV/EBITDA
-24.94
Overvalued EV/EBITDA
6.04
Undervalued EV/EBITDA
-36.70

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
361.97
Current PS
171.83
Overvalued PS
957.92
Undervalued PS
-233.98

Financials

AI Analysis
Annual
Quarterly

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Whales Holding SMMT

B
Baker Bros. Advisors LP
Holding
SMMT
+1.44%
3M Return
R
Rock Springs Capital Management LP
Holding
SMMT
-5.31%
3M Return

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Frequently Asked Questions

What is Summit Therapeutics Inc (SMMT) stock price today?

The current price of SMMT is 18.96 USD — it has increased 11.66

What is Summit Therapeutics Inc (SMMT)'s business?

Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial.

What is the price predicton of SMMT Stock?

Wall Street analysts forecast SMMT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SMMT is42.49 USD with a low forecast of 18.00 USD and a high forecast of 131.90 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Summit Therapeutics Inc (SMMT)'s revenue for the last quarter?

Summit Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Summit Therapeutics Inc (SMMT)'s earnings per share (EPS) for the last quarter?

Summit Therapeutics Inc. EPS for the last quarter amounts to -0.29 USD, increased 262.50

How many employees does Summit Therapeutics Inc (SMMT). have?

Summit Therapeutics Inc (SMMT) has 265 emplpoyees as of April 01 2026.

What is Summit Therapeutics Inc (SMMT) market cap?

Today SMMT has the market capitalization of 14.70B USD.