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SMMT Overview

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$
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0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
29.200
Open
25.400
VWAP
26.80
Vol
8.35M
Mkt Cap
19.50B
Low
24.920
Amount
223.71M
EV/EBITDA(TTM)
--
Total Shares
776.08M
EV
18.78B
EV/OCF(TTM)
--
P/S(TTM)
--
Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial.
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Events Timeline

(ET)
2026-04-17
10:50:00
Biotech Stocks Summit Therapeutics and Fractyl Health See Substantial Increase in Search Activity
select
2026-03-27 (ET)
2026-03-27
11:40:00
Biotech Stocks Surge in Search Activity, Radiopharm Up 2566.66%
select

News

NASDAQ.COM
8.0
04-16NASDAQ.COM
Aehr Test Systems and MongoDB Show Active Options Trading
  • Aehr Options Volume: Aehr Test Systems has seen an options trading volume of 23,837 contracts today, equating to approximately 2.4 million shares, which represents 69.3% of its average daily trading volume of 3.4 million shares over the past month.
  • High Contract Analysis: Notably, the $90 strike call option expiring on April 17, 2026, has traded 1,933 contracts today, representing about 193,300 underlying shares, indicating market expectations for future price increases.
  • MongoDB Options Activity: MongoDB Inc recorded an options trading volume of 10,127 contracts, representing approximately 1.0 million shares or 65.6% of its average daily trading volume of 1.5 million shares over the past month, highlighting investor interest in its future performance.
  • Put Option Trading: The $230 strike put option expiring on April 17, 2026, has seen 714 contracts traded today, representing about 71,400 underlying shares, reflecting market concerns regarding potential downside risks for MongoDB.
moomoo
4.0
04-08moomoo
Stifel Begins Coverage of Summit Therapeutics Inc with a Buy Rating and Sets Price Target at $45
  • Company Overview: Summit Therapeutics is focused on developing innovative therapies, particularly in the field of rare diseases and infectious diseases.

  • Investment Rating: The company has received a "Buy" rating from analysts, indicating positive expectations for its stock performance.

  • Price Target: Analysts have set a price target of $45 for Summit Therapeutics, suggesting significant potential for growth.

  • Market Position: The company is positioned to capitalize on its therapeutic developments, which may enhance its market presence and investor interest.

CNBC
6.5
03-31CNBC
Citi Identifies Stocks with Upside Amid U.S.-Iran Conflict
  • Market Turmoil Impact: The ongoing U.S.-Iran conflict has caused concern among investors, leading to a nearly 8% drop in the S&P 500 in March, marking its worst monthly performance since 2022.
  • Citi Analyst Strategy: Citi analyst Richard Schlatter sought stocks that could sidestep recent volatility by overlaying crowding composites tracked by Citi, identifying stocks with positive catalysts that are not relatively crowded, aiming for a favorable reaction to fundamental tailwinds.
  • Delta Air Lines Outlook: Delta Air Lines' stock has only dropped 3.8% this month, despite a nearly 9% decline in 2026, with Wall Street expecting a rebound; the average analyst price target from LSEG suggests a potential 25% gain over the next year.
  • Summit Therapeutics Performance: Summit Therapeutics' stock has risen 2.4% since the war began, with a long crowding composite of just 18.1%, and analysts are generally bullish, as 13 out of 18 covering analysts rate it a buy or strong buy.
Newsfilter
9.0
03-27Newsfilter
Summit Presents Updated Ivonescimab Data at ELCC 2026
  • Clinical Data Update: Summit Therapeutics will present updated data on ivonescimab at the 2026 European Lung Cancer Congress, covering intracranial anti-tumor activity from the global HARMONi Phase III study, which is expected to attract industry attention and enhance the company's reputation in cancer immunotherapy.
  • Improved Intracranial Survival: In the HARMONi study, patients receiving ivonescimab plus chemotherapy showed an intracranial progression-free survival (PFS) of 10.1 months compared to 6.5 months for chemotherapy alone, indicating the potential advantage of this therapy in EGFR-mutated non-small cell lung cancer (NSCLC) patients.
  • Quality of Life Assessment: The second poster will showcase health-related quality of life data comparing ivonescimab with placebo plus chemotherapy, emphasizing the drug's potential to improve patient quality of life, which may enhance market recognition.
  • Multiple Ongoing Trials: Ivonescimab is currently involved in over 15 Phase III clinical trials globally, covering various cancer types, indicating the company's extensive positioning in cancer treatment and future growth potential.
Yahoo Finance
4.0
03-26Yahoo Finance
Jefferies Downgrades Summit Therapeutics with Target Price Cut
  • Rating Downgrade: Jefferies downgraded Summit Therapeutics from Buy to Hold, reflecting a cautious market outlook on the company's future performance amid uncertainties.
  • Target Price Revision: The target price was significantly cut from $42 to $15, indicating a reassessment of the company's growth potential, which may impact investor confidence and lead to stock price volatility.
  • Clinical Trial Progress: Summit completed screening for the squamous cohort in Q1 2026, with enrollment for the non-squamous cohort expected to finish in the second half of the year, potentially supporting future treatment options for the company.
  • Financial Performance: The company reported an adjusted EPS of -$0.14 for Q4, exceeding the market consensus of -$0.01, demonstrating operational resilience despite a challenging overall market environment.
Fool
8.5
03-25Fool
Summit Therapeutics Faces FDA Review Risk for Ivonescimab
  • Regulatory Application Progress: Summit Therapeutics has filed for FDA approval of ivonescimab, which is already approved in China; however, survival data from Western countries has not shown statistical significance, potentially jeopardizing its marketing authorization.
  • Market Valuation Changes: Currently, Summit's market cap stands at $12 billion, approximately 48% higher than Axsome and 17% higher than Madrigal, but if the FDA declines ivonescimab, the stock could face a drop of over 20%.
  • Competitor Dynamics: Axsome Therapeutics and Madrigal Pharmaceuticals reported revenue growth of 65.5% and 432% in 2025, respectively, indicating strong market potential that could see them surpass Summit in the near future.
  • Investor Risk Assessment: While Summit has long-term potential in oncology, its short-term outlook is uncertain, prompting investors to carefully evaluate risks, especially in light of possible negative clinical trial outcomes.
Wall Street analysts forecast SMMT stock price to rise
12 Analyst Rating
Wall Street analysts forecast SMMT stock price to rise
8 Buy
3 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
18.00
Averages
42.49
High
131.90
Current: 0.000
sliders
Low
18.00
Averages
42.49
High
131.90
Guggenheim
Buy
maintain
$40
AI Analysis
2026-04-21
New
Reason
Guggenheim
Price Target
$40
AI Analysis
2026-04-21
New
maintain
Buy
Reason
Guggenheim contends that investors "should be positively surprised" to see Summit Therapeutics' partner Akeso's first disclosure for HARMONi-6 data selected for the ASCO plenary session. Many feared these data would show the overall survival hazard ratio "land somewhere around 0.80-0.85," but the firm thinks it will now be presumed to be a better less than 0.80 result given the selection as an ASCO plenary. The firm has a Buy rating and $40 price target on Summit Therapeutics shares.
Stifel
Buy
initiated
$45
2026-04-07
Reason
Stifel
Price Target
$45
2026-04-07
initiated
Buy
Reason
Stifel initiated coverage of Summit Therapeutics with a Buy rating and $45 price target. The firm believes the company's ivonescimab, a "first-in-class" PD-1xVEGF bispecific antibody, is positioned to lead in what could be a $200B drug class. The growing strategic capital committed to "fast-followers" suggests scarcity value in Summit's competitive positioning, the analyst tells investors in a research note. Stifel thinks the "de-risking" of Summit's first-line lung cancer trials "could trigger an overdue re-rating" of the shares.
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Valuation Metrics

The current forward P/E ratio for Summit Therapeutics Inc (SMMT.O) is 3.72, compared to its 5-year average forward P/E of -21.53. For a more detailed relative valuation and DCF analysis to assess Summit Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-21.53
Current PE
3.72
Overvalued PE
5.38
Undervalued PE
-48.45

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-15.49
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
5.94
Undervalued EV/EBITDA
-36.93

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
355.92
Current PS
293.01
Overvalued PS
937.38
Undervalued PS
-225.54

Financials

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Whales Holding SMMT

B
Baker Bros. Advisors LP
Holding
SMMT
+3.17%
3M Return
R
Rock Springs Capital Management LP
Holding
SMMT
-0.00%
3M Return

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Frequently Asked Questions

What is Summit Therapeutics Inc (SMMT) stock price today?

The current price of SMMT is 26.28 USD — it has increased 4.62

What is Summit Therapeutics Inc (SMMT)'s business?

Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial.

What is the price predicton of SMMT Stock?

Wall Street analysts forecast SMMT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SMMT is42.49 USD with a low forecast of 18.00 USD and a high forecast of 131.90 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Summit Therapeutics Inc (SMMT)'s revenue for the last quarter?

Summit Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Summit Therapeutics Inc (SMMT)'s earnings per share (EPS) for the last quarter?

Summit Therapeutics Inc. EPS for the last quarter amounts to -0.29 USD, increased 262.50

How many employees does Summit Therapeutics Inc (SMMT). have?

Summit Therapeutics Inc (SMMT) has 265 emplpoyees as of April 21 2026.

What is Summit Therapeutics Inc (SMMT) market cap?

Today SMMT has the market capitalization of 19.50B USD.