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ASND Overview

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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
232.357
Open
228.750
VWAP
229.26
Vol
393.51K
Mkt Cap
14.10B
Low
225.855
Amount
90.22M
EV/EBITDA(TTM)
--
Total Shares
61.98M
EV
14.63B
EV/OCF(TTM)
226.63
P/S(TTM)
16.53
Ascendis Pharma A/S is a Denmark-based company that manufactures pharmaceutical products. The Company produces products for the treatments of growth hormone deficiency, endocrinology, central nervous system disorders, infectious diseases, and diabetes. The Company operates globally though its subsidiaries: Ascendis Pharma GmbH (Germany), Ascendis Pharma, Inc. (Delaware, United States), Ascendis Pharma Endocrinology, Inc. (Delaware, United States), Ascendis Pharma, Ophthalmology Division A/S (Denmark), Ascendis Pharma, Endocrinology Division A/S (Denmark), Ascendis Pharma Bone Diseases A/S (Denmark), Ascendis Pharma Growth Disorders A/S (Denmark) and Ascendis Pharma Oncology Division A/S (Denmark).
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Events Timeline

(ET)
2026-02-27
18:30:00
Ascendis Pharma Trading Resumes
select
2026-02-27
18:00:00
Ascendis Pharma's Yuviwel Receives FDA Accelerated Approval
select
2026-02-11 (ET)
2026-02-11
16:10:00
Ascendis Pharma Reports Q4 Revenue of €247.5M
select

News

NASDAQ.COM
9.0
03-06NASDAQ.COM
FDA Grants Approvals for Multiple New Therapies
  • Hernexeos Approval: On February 26, 2026, the FDA granted accelerated approval to Boehringer Ingelheim's Hernexeos as a first-line treatment for adult patients with HER2-mutant advanced non-small cell lung cancer, representing a significant milestone that could improve patient prognosis and reduce the risk of brain metastases for the 2-4% of NSCLC cases affected.
  • Yuviwel Launch: Ascendis Pharma secured FDA approval on February 27, 2026, for Yuviwel, the first and only therapy providing continuous systemic exposure to C-type natriuretic peptide (CNP) for children aged 2 and older with achondroplasia, which is expected to enhance treatment adherence compared to daily alternatives.
  • Palynziq Indication Expansion: BioMarin received FDA approval on February 27, 2026, to expand Palynziq's indication to include pediatric patients aged 12 and older with phenylketonuria, which is anticipated to further drive sales growth, having generated $433 million in revenue in 2025.
  • Sogroya New Indications: Novo Nordisk obtained FDA approval on February 27, 2026, for Sogroya's expanded indications for various growth disorders, offering a once-weekly growth hormone alternative that is expected to improve treatment adherence and alleviate the burden of daily injections for families.
Yahoo Finance
8.5
03-05Yahoo Finance
Ascendis Pharma Plans 2026 U.S. Launch of YUVIWEL Following FDA Approval
  • FDA Approval Milestone: Ascendis Pharma's YUVIWEL has received FDA approval as the first once-weekly treatment for children with achondroplasia, marking the company's third FDA-approved drug and significantly enhancing its competitive position in the rare disease market.
  • Clinical Data Highlights: In the pivotal ApproaCH trial, children treated with navepegritide achieved an annualized growth velocity (AGV) of 5.9 cm/year compared to 4.4 cm/year for placebo, demonstrating a significant treatment difference of 1.5 cm/year, indicating the drug's clinical efficacy.
  • Commercialization Strategy: Ascendis plans to support the commercial availability of YUVIWEL in early Q2 2026, expecting a premium pricing strategy, and aims to maximize market penetration through the Ascendis Signature Access Program, which includes reimbursement support and patient assistance.
  • Market Opportunity and Future Milestones: Ascendis estimates approximately 2,600 pediatric patients with achondroplasia in the U.S., with plans to complete enrollment in a study for children aged 0-2 by 2026 and aims for European approval by the end of the year, further expanding market potential.
moomoo
5.0
03-02moomoo
Ascendis Pharma A/S (ASND.US) Officer Plans to Sell $4.44 Million in Common Stock via Form 144
  • Stock Sale Announcement: Jensen Michael Wolff intends to sell 18,349 shares of Ascendis Pharma A/S common stock on March 2, with a total market value of approximately $4.44 million.

  • Reduction in Shareholding: Wolff has reduced his shareholding in Ascendis Pharma A/S by 10,000 shares since December 4, 2025, with a total value of around $2.08 million.

Benzinga
9.0
03-02Benzinga
Ascendis Pharma Receives FDA Approval for New Drug
  • FDA Approval: Ascendis Pharma's Yuviwel (navepegritide) has received FDA approval as the first once-weekly treatment for children with achondroplasia, expected to be available in Q2 2026, significantly enhancing the company's competitive position in the rare pediatric disease market.
  • Clinical Trial Support: The approval is based on data from three randomized clinical trials aimed at promoting linear growth in children aged two and older, marking a significant advancement in treatment options for achondroplasia and addressing the urgent market need for effective therapies.
  • Positive Market Reaction: Following the FDA approval, Ascendis Pharma's stock rose 3.21% to $241.00 during Monday's premarket trading, reflecting investor optimism regarding the new drug's market potential and indicating the company's growth prospects in the biopharmaceutical sector.
  • Optimistic Analyst Ratings: The stock currently holds a Buy rating with an average price target of $261.21, with analysts from Oppenheimer and Wedbush raising their targets, indicating increased market confidence in Ascendis Pharma's future performance.
NASDAQ.COM
9.0
02-28NASDAQ.COM
Ascendis Pharma Receives FDA Accelerated Approval for YUVIWEL
  • FDA Accelerated Approval: Ascendis Pharma's YUVIWEL (navepegritide) has received FDA accelerated approval, becoming the first once-weekly treatment aimed at increasing linear growth in children aged two years and older with achondroplasia, marking a significant breakthrough in the rare disease sector.
  • Clinical Trial Support: The approval is based on data from three randomized, double-blind, placebo-controlled clinical trials demonstrating significant improvements in annualized growth velocity (AGV), with future continued approval dependent on verification of clinical benefits in confirmatory trials, highlighting the company's commitment to scientific research.
  • Patient Services Program: Ascendis plans to launch patient services through its Ascendis Signature Access Program (A.S.A.P.), offering treatment navigation and financial assistance, aimed at enhancing patient experience and strengthening market competitiveness.
  • Positive Market Reaction: Following the FDA approval, ASND stock rose 1.97% in regular trading and further increased by 4.07% in after-hours trading, reflecting investor optimism regarding the company's future growth potential.
seekingalpha
9.0
02-28seekingalpha
FDA Approves Ascendis Pharma's Yuviwel for Dwarfism Treatment
  • Drug Approval: The US FDA has granted approval for Ascendis Pharma's Yuviwel (navepegritide) to treat children with achondroplasia, marking a significant advancement for the company in the pediatric growth disorder treatment space.
  • Dosing Regimen: Yuviwel is administered once weekly for children aged two years and older, with availability expected in Q2 2025, addressing the urgent market demand for effective treatment options.
  • Post-Market Trial Requirement: The FDA mandates Ascendis to conduct post-marketing trials to confirm the treatment's benefits, which will influence the company's future clinical research and market strategy.
  • Improvement in Growth Velocity: The approval was based on significant improvements in annualized growth velocity, demonstrating the drug's effectiveness in enhancing children's growth potential, which could drive Ascendis's further development in the biopharmaceutical market.
Wall Street analysts forecast ASND stock price to rise
13 Analyst Rating
Wall Street analysts forecast ASND stock price to rise
13 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
240.00
Averages
277.08
High
342.00
Current: 0.000
sliders
Low
240.00
Averages
277.08
High
342.00
Stifel
Buy
maintain
$325 -> $332
AI Analysis
2026-03-04
Reason
Stifel
Price Target
$325 -> $332
AI Analysis
2026-03-04
maintain
Buy
Reason
Stifel raised the firm's price target on Ascendis Pharma to $332 from $325 and keeps a Buy rating on the shares following the accelerated approval of Yuviwel. The firm thinks the approval represents "a solid win" for Ascendis as they continue to expand their commercial portfolio. Stifel sees upside to shares if the weekly doing versus daily dosing profile drives disruption and increased uptake within the U.S./global Achondroplasia market, the firm told investors in a research note.
RBC Capital
Outperform
maintain
$250 -> $275
2026-03-03
Reason
RBC Capital
Price Target
$250 -> $275
2026-03-03
maintain
Outperform
Reason
RBC Capital raised the firm's price target on Ascendis Pharma to $275 from $250 and keeps an Outperform rating on the shares. The firm cites the FDA having approved Yuviwel for achondroplasia in patients 2 years of age and older as well as having granted the company a PRV - Priority Review Voucher. RBC continues to like the set-up on Ascendis given its "extensive checks" suggesting that Yorvipath will likely be a multi-billion dollar drug, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Ascendis Pharma A/S (ASND.O) is 94.95, compared to its 5-year average forward P/E of -3.12. For a more detailed relative valuation and DCF analysis to assess Ascendis Pharma A/S's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.12
Current PE
94.95
Overvalued PE
49.07
Undervalued PE
-55.32

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.60
Current EV/EBITDA
95.32
Overvalued EV/EBITDA
51.75
Undervalued EV/EBITDA
-62.95

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
79.80
Current PS
9.51
Overvalued PS
202.36
Undervalued PS
-42.77

Financials

AI Analysis
Annual
Quarterly

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ASND logo
ASND
Ascendis Pharma A/S
13.37B

Whales Holding ASND

A
ARS Investment Partners, LLC
Holding
ASND
+16.70%
3M Return
F
Frazier Life Sciences Management, LP
Holding
ASND
+8.24%
3M Return
A
Artal Group S.A.
Holding
ASND
+7.65%
3M Return
W
Westfield Capital Management Company, L.P.
Holding
ASND
+7.28%
3M Return
R
Rice Hall James & Associates, LLC
Holding
ASND
+6.92%
3M Return
V
Vestal Point Capital, LP
Holding
ASND
+6.42%
3M Return

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Frequently Asked Questions

What is Ascendis Pharma A/S (ASND) stock price today?

The current price of ASND is 229.56 USD — it has increased 0.91

What is Ascendis Pharma A/S (ASND)'s business?

Ascendis Pharma A/S is a Denmark-based company that manufactures pharmaceutical products. The Company produces products for the treatments of growth hormone deficiency, endocrinology, central nervous system disorders, infectious diseases, and diabetes. The Company operates globally though its subsidiaries: Ascendis Pharma GmbH (Germany), Ascendis Pharma, Inc. (Delaware, United States), Ascendis Pharma Endocrinology, Inc. (Delaware, United States), Ascendis Pharma, Ophthalmology Division A/S (Denmark), Ascendis Pharma, Endocrinology Division A/S (Denmark), Ascendis Pharma Bone Diseases A/S (Denmark), Ascendis Pharma Growth Disorders A/S (Denmark) and Ascendis Pharma Oncology Division A/S (Denmark).

What is the price predicton of ASND Stock?

Wall Street analysts forecast ASND stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ASND is277.08 USD with a low forecast of 240.00 USD and a high forecast of 342.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Ascendis Pharma A/S (ASND)'s revenue for the last quarter?

Ascendis Pharma A/S revenue for the last quarter amounts to 247.50M USD, decreased

What is Ascendis Pharma A/S (ASND)'s earnings per share (EPS) for the last quarter?

Ascendis Pharma A/S. EPS for the last quarter amounts to -0.55 USD, decreased

How many employees does Ascendis Pharma A/S (ASND). have?

Ascendis Pharma A/S (ASND) has 1189 emplpoyees as of March 12 2026.

What is Ascendis Pharma A/S (ASND) market cap?

Today ASND has the market capitalization of 14.10B USD.