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ASND Overview

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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
237.000
Open
233.600
VWAP
232.69
Vol
908.47K
Mkt Cap
15.14B
Low
230.230
Amount
211.39M
EV/EBITDA(TTM)
1.09K
Total Shares
65.58M
EV
14.71B
EV/OCF(TTM)
208.42
P/S(TTM)
14.45
Ascendis Pharma A/S is a Denmark‑based biopharmaceutical company operating within the life sciences and biotechnology sector. The Company scope of activity includes discovery, development, and commercialization of innovative therapies for rare diseases and serious chronic conditions with significant unmet medical needs where a clinically validated parent drug or pathway is suitable to company technologies. Ascendis Pharma A/S focuses on the endocrinology area and has a pipeline of three independent rare disease product candidates, such as Growth Hormone Deficiency (GHD), Hypoparathyroidism and Achondroplasia. The second therapeutic area is oncology, where the company focuses immunotherapy to targeted therapies.
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Events Timeline

(ET)
2026-06-14
17:00:00
Ascendis Pharma Releases Week 182 Data for TransCon PTH
select
2026-05-07 (ET)
2026-05-07
09:10:00
Company Reports Q1 Revenue of EUR 246.6M
select
2026-04-20 (ET)
2026-04-20
08:10:00
Ascendis Pharma Begins Trading Ordinary Shares on Nasdaq
select

News

Newsfilter
2.0
06-13Newsfilter
Ascendis Pharma Reports Three-Year Data on TransCon PTH Efficacy
  • Sustained Long-term Efficacy: In the three-and-a-half-year PaTHway trial, TransCon PTH demonstrated an 86% response rate for the multi-component endpoint, successfully replicating endogenous parathyroid hormone actions and significantly improving patients' quality of life.
  • Independence from Conventional Therapy: The trial showed that 100% of patients achieved independence from active vitamin D, and 96% maintained calcium intake below 600 mg/day, indicating TransCon PTH's effective replacement of traditional therapies.
  • Improved Kidney Function: At Week 182, the mean estimated glomerular filtration rate (eGFR) reached 80.2 mL/min/1.73 m², reflecting an increase of 11.0 mL/min/1.73 m² from baseline, showcasing TransCon PTH's positive impact on renal function.
  • Good Safety Profile: Throughout the trial, TransCon PTH was well-tolerated with no new safety signals identified, and all adverse events were mild or moderate, ensuring patient safety during treatment.
NASDAQ.COM
2.0
06-12NASDAQ.COM
Ascendis Pharma Reports Five-Year Data on TransCon PTH for Hypoparathyroidism
  • Sustained Efficacy: Ascendis Pharma's TransCon PTH demonstrated sustained efficacy in the five-year Phase 2 trial, with 82% of patients achieving normal serum calcium levels by Week 266 without active vitamin D, indicating its potential as a new standard of care for hypoparathyroidism.
  • Kidney Function Improvement: The trial showed a sustained increase in mean eGFR from baseline, reflecting the therapy's effectiveness in improving calcium levels while countering age-related kidney function decline, thereby enhancing patients' quality of life.
  • Stable Bone Density: Bone mineral density scores were corrected early and remained stable over five years, highlighting TransCon PTH's long-term benefits for bone health and reinforcing its position as a new standard treatment for chronic hypoparathyroidism.
  • Good Safety Profile: The therapy was generally well tolerated with no new safety signals identified; most adverse events were mild or moderate, and no patients discontinued treatment, demonstrating the safety and efficacy of TransCon PTH.
seekingalpha
9.0
06-11seekingalpha
Ascendis Pharma Reports Sustained Efficacy of Yorvipath Over Five Years
  • Sustained Efficacy: Ascendis Pharma's adult hypoparathyroidism treatment Yorvipath (palopegteriparatide) demonstrated sustained efficacy in a five-year phase 2 trial, with 82% of patients achieving serum calcium levels within the normal range at week 266, indicating the treatment's effectiveness in improving patient health.
  • Multi-System Impact: The hormone replacement therapy showed a balanced and beneficial impact on key target organ systems—kidneys, small intestine, CNS, and bones—evidenced by normalized and stable urine calcium, serum calcium, quality of life, and bone mineral density, highlighting its therapeutic potential across multiple dimensions.
  • Trial Design: The PaTH Forward trial enrolled 59 participants, who underwent a four-week randomized, double-blind, placebo-controlled period followed by a 262-week open-label extension, with only 3 patients not completing the five-year study, demonstrating good tolerability and engagement.
  • Market Outlook: As Ascendis Pharma enters a growth phase, its potential in the rare endocrine drug market is widely recognized, which is expected to enhance its future market performance and investment appeal.
Newsfilter
8.5
06-08Newsfilter
Ascendis Pharma to Present New Data at ENDO 2026
  • Clinical Data Sharing: Ascendis Pharma will present the latest clinical trial data on hypoparathyroidism, achondroplasia, and pediatric growth hormone deficiency through two oral presentations and three posters at the 2026 ENDO meeting, showcasing the potential of its innovative therapies.
  • Key Research Findings: At the conference, Ascendis will highlight the long-term safety and efficacy of TransCon PTH, based on results from multiple clinical trials, emphasizing its application prospects in treating patients with hypoparathyroidism.
  • Advancements in Achondroplasia Treatment: Ascendis will also present 52-week results of Navepegritide combined with Lonapegsomatropin for treating children with achondroplasia, further validating its potential to improve patient growth and quality of life.
  • Global Impact: This presentation not only enhances Ascendis' leadership position in rare endocrine diseases but may also attract more investor attention to its innovative technology platform, driving future business growth.
Fool
2.0
05-14Fool
Siren Fully Liquidates Ascendis Pharma Holdings
  • Liquidation Transaction: On May 14, 2026, Siren disclosed in an SEC filing that it sold its entire holding of 235,862 shares of Ascendis Pharma A/S, with an estimated transaction value of $52.87 million, reflecting a cautious outlook on the company's future prospects.
  • Position Change: This sale resulted in a $50.30 million decrease in Siren's quarter-end position in Ascendis, which includes both the sale and price effects, indicating market reactions to the stock's performance.
  • Company Performance: As of May 13, 2026, Ascendis Pharma's stock was priced at $243.58, up 50% over the past year and outperforming the S&P 500 by 24 percentage points, highlighting its market appeal in the rare disease sector.
  • Financial Status: Ascendis Pharma reported first-quarter revenues exceeding €247 million, primarily driven by €197 million in YORVIPATH sales, although its net income fluctuated significantly due to the recognition of a deferred tax asset, raising questions about its ability to achieve sustainable cash flow growth in the future.
seekingalpha
9.5
05-06seekingalpha
Ascendis Pharma to Announce Q1 Earnings on May 7
  • Earnings Announcement Schedule: Ascendis Pharma A/S is set to release its Q1 2023 earnings report on May 7 before market open, with a consensus EPS estimate of -$0.17, indicating challenges in profitability.
  • Revenue Expectations: Analysts estimate revenue at $315.79 million, reflecting cautious market sentiment regarding the company's product sales and market performance, which could impact investor confidence.
  • Historical Financial Data: Historical financial data for Ascendis Pharma A/S will provide investors with crucial context to assess performance trends and future growth potential, especially in the increasingly competitive biopharmaceutical sector.
  • Market Reaction Anticipation: As the earnings report approaches, market reactions to Ascendis Pharma may be influenced by the comparison of actual results to expectations, prompting investors to closely monitor stock price fluctuations post-announcement.
Wall Street analysts forecast ASND stock price to rise
13 Analyst Rating
Wall Street analysts forecast ASND stock price to rise
13 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
240.00
Averages
277.08
High
342.00
Current: 0.000
sliders
Low
240.00
Averages
277.08
High
342.00
Citi
Eric Joseph
Buy
initiated
$355
AI Analysis
2026-05-18
Reason
Citi
Eric Joseph
Price Target
$355
AI Analysis
2026-05-18
initiated
Buy
Reason
Citi analyst Eric Joseph initiated coverage of Ascendis Pharma with a Buy rating and $355 price target. Citi is "impressed" with Yorvipath's launch and sees potential upside to consensus estimates starting in Q2. The drug is on a path to blockbuster status in 2026, the analyst tells investors in a research note.
Evercore ISI
Outperform
maintain
$324 -> $329
2026-05-15
Reason
Evercore ISI
Price Target
$324 -> $329
2026-05-15
maintain
Outperform
Reason
Evercore ISI raised the firm's price target on Ascendis Pharma to $329 from $324 and keeps an Outperform rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ASND
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Valuation Metrics

The current forward P/E ratio for Ascendis Pharma A/S (ASND.O) is 14.27, compared to its 5-year average forward P/E of 1.17. For a more detailed relative valuation and DCF analysis to assess Ascendis Pharma A/S's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
1.17
Current PE
14.27
Overvalued PE
53.71
Undervalued PE
-51.38

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
2.14
Current EV/EBITDA
73.85
Overvalued EV/EBITDA
83.34
Undervalued EV/EBITDA
-79.06

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
55.74
Current PS
7.92
Overvalued PS
125.37
Undervalued PS
-13.89

Financials

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ASND logo
ASND
Ascendis Pharma A/S
13.37B

Whales Holding ASND

A
ARS Investment Partners, LLC
Holding
ASND
+37.81%
3M Return
F
Fred Alger Management, LLC
Holding
ASND
+26.14%
3M Return
A
Avoro Capital Advisors LLC
Holding
ASND
+24.79%
3M Return
S
Stacey Braun Associates, Inc.
Holding
ASND
+22.52%
3M Return
I
IMC Trading B.V.
Holding
ASND
+21.04%
3M Return
B
Brevan Howard Capital Management LP
Holding
ASND
+19.11%
3M Return

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Frequently Asked Questions

What is Ascendis Pharma A/S (ASND) stock price today?

The current price of ASND is 230.83 USD — it has decreased -0.14

What is Ascendis Pharma A/S (ASND)'s business?

Ascendis Pharma A/S is a Denmark‑based biopharmaceutical company operating within the life sciences and biotechnology sector. The Company scope of activity includes discovery, development, and commercialization of innovative therapies for rare diseases and serious chronic conditions with significant unmet medical needs where a clinically validated parent drug or pathway is suitable to company technologies. Ascendis Pharma A/S focuses on the endocrinology area and has a pipeline of three independent rare disease product candidates, such as Growth Hormone Deficiency (GHD), Hypoparathyroidism and Achondroplasia. The second therapeutic area is oncology, where the company focuses immunotherapy to targeted therapies.

What is the price predicton of ASND Stock?

Wall Street analysts forecast ASND stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ASND is277.08 USD with a low forecast of 240.00 USD and a high forecast of 342.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Ascendis Pharma A/S (ASND)'s revenue for the last quarter?

Ascendis Pharma A/S revenue for the last quarter amounts to 246.60M USD, increased 144.27

What is Ascendis Pharma A/S (ASND)'s earnings per share (EPS) for the last quarter?

Ascendis Pharma A/S. EPS for the last quarter amounts to 9.75 USD, decreased -717.09

How many employees does Ascendis Pharma A/S (ASND). have?

Ascendis Pharma A/S (ASND) has 1189 emplpoyees as of June 21 2026.

What is Ascendis Pharma A/S (ASND) market cap?

Today ASND has the market capitalization of 15.14B USD.