Pfizer Faces Patent Cliff Challenges Amid Turnaround Potential
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1h ago
0mins
Source: Fool
- Vaccine Demand Decline: Pfizer experienced significant gains during the pandemic due to its COVID-19 vaccine, but as demand has waned, the stock has plummeted over 50% from its 2021 peak, indicating investor concerns about future growth prospects.
- Patent Cliff Risks: With multiple patents set to expire, Pfizer faces potential rapid declines in revenue and profit, particularly as investor confidence in its drug development pipeline has been shaken by the lack of new blockbuster drugs to offset these losses.
- Acquisitions and Partnerships: Pfizer has acquired a company with a promising GLP-1 drug pipeline and agreed to distribute a GLP-1 therapy for a Chinese firm, demonstrating its proactive strategies to mitigate risks associated with patent expirations.
- Attractive Dividend Yield: With a current dividend yield of 6.7%, Pfizer allocates all profits to dividends, which may appeal to investors; however, caution is advised due to the potential for future dividend cuts impacting cash flow.
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Analyst Views on PFE
Wall Street analysts forecast PFE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PFE is 28.56 USD with a low forecast of 24.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
16 Analyst Rating
5 Buy
11 Hold
0 Sell
Moderate Buy
Current: 26.100
Low
24.00
Averages
28.56
High
35.00
Current: 26.100
Low
24.00
Averages
28.56
High
35.00
About PFE
Pfizer Inc. is a research-based, global biopharmaceutical company. The Company is engaged in the discovery, development, manufacture, marketing, sale and distribution of biopharmaceutical products worldwide. Its Biopharma segment includes the Pfizer U.S. Commercial Division, and the Pfizer International Commercial Division. Its product categories include oncology, primary care and specialty care. Its oncology products include Ibrance, Xtandi, Padcev, Adcetris, Inlyta, Lorbrena, Bosulif, Tukysa, Braftovi, Mektovi, Orgovyx, Elrexfio, Tivdak and Talzenna. Its primary care products include Eliquis, Nurtec ODT/Vydura, Zavzpret, the Prevnar family, Comirnaty, Abrysvo, FSME/IMMUN-TicoVac, Nimenrix, Trumenba, and Paxlovid. Its specialty care products include Xeljanz, Enbrel (outside the United States and Canada), Inflectra, Abrilada, Cibinqo, Litfulo, Eucrisa, Velsipity, the Vyndaqel family, Genotropin, BeneFIX, Xyntha, Somavert, Ngenla, Hympavzi, Sulperazon, Zavicefta, Octagam and others.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Pfizer Faces Patent Cliffs and Turnaround Challenges
- Stock Price Decline: Pfizer's stock has lost over 50% since its 2021 peak, reflecting investor concerns about future growth, particularly after the decline in demand for its COVID-19 vaccine, which has significantly weakened market confidence in the company.
- Patent Cliff Risks: Pfizer is approaching multiple patent expirations, which could lead to rapid declines in revenue and profit, especially given the lack of new drugs to fill this gap, putting pressure on the company's long-term growth outlook.
- Pipeline Issues: The abandonment of Pfizer's internally developed GLP-1 weight loss drug indicates that its development pipeline is not as strong as hoped, raising doubts among investors about the company's ability to launch new blockbuster drugs, further exacerbating negative sentiment.
- Dividend Appeal: Despite a high dividend yield of 6.7%, investors should be cautious about the sustainability of these payments, as the company devotes all profits to dividends, particularly in light of the turnaround challenges it faces.

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Pfizer Faces Patent Cliff Challenges Amid Turnaround Potential
- Vaccine Demand Decline: Pfizer experienced significant gains during the pandemic due to its COVID-19 vaccine, but as demand has waned, the stock has plummeted over 50% from its 2021 peak, indicating investor concerns about future growth prospects.
- Patent Cliff Risks: With multiple patents set to expire, Pfizer faces potential rapid declines in revenue and profit, particularly as investor confidence in its drug development pipeline has been shaken by the lack of new blockbuster drugs to offset these losses.
- Acquisitions and Partnerships: Pfizer has acquired a company with a promising GLP-1 drug pipeline and agreed to distribute a GLP-1 therapy for a Chinese firm, demonstrating its proactive strategies to mitigate risks associated with patent expirations.
- Attractive Dividend Yield: With a current dividend yield of 6.7%, Pfizer allocates all profits to dividends, which may appeal to investors; however, caution is advised due to the potential for future dividend cuts impacting cash flow.

Continue Reading





