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PFE Should I Buy

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Intellectia

Should You Buy Pfizer Inc (PFE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
25.680
1 Day change
-3.02%
52 Week Range
28.750
Analysis Updated At
2026/04/24
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Pfizer Inc (PFE) is not a strong buy at the moment for a beginner investor with a long-term focus. The stock lacks immediate positive catalysts, has weak financial performance, and no strong trading signals. While there are some positive developments in its pipeline, the overall sentiment and technical indicators suggest holding off on investment for now.

Technical Analysis

The MACD is negatively expanding (-0.0928), RSI is neutral at 30.273, and moving averages are converging, indicating no clear bullish or bearish trend. The stock is trading near its support level (S1: 26.57), with resistance at 27.13, showing limited upward momentum.

Options Data

Bullish
Open Interest Put-Call Ratio
Neutral
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
11
Buy
4

Positive Catalysts

  • Pfizer's weight management treatment Xianweiying is now available for pre-order in China, and the company presented advancements in cancer treatments at the ASCO meeting. Analysts like Argus and Guggenheim have expressed confidence in the company's long-term growth potential.

Neutral/Negative Catalysts

  • Weak Q4 financials with a significant drop in revenue (-1.16% YoY), net income (-501.95% YoY), and EPS (-514.29% YoY). The CDC's blocking of a COVID-19 vaccine study raises concerns about vaccine-related controversies. Competitors like AbbVie and Merck are showing stronger financial and strategic positions.

Financial Performance

In 2025/Q4, Pfizer's revenue dropped to $17.56 billion (-1.16% YoY), net income fell significantly to -$1.65 billion (-501.95% YoY), and EPS dropped to -$0.29 (-514.29% YoY). Gross margin increased to 64.15% (+6.00% YoY), but overall financial performance remains weak.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are mixed on Pfizer. Recent ratings include UBS raising the price target to $27 (Neutral), Morgan Stanley raising it to $28 (Equal Weight), and RBC Capital maintaining an Underperform rating with a $25 target. Positive ratings from Guggenheim ($36 target) and Argus ($35 target) reflect confidence in long-term growth but do not address immediate challenges.

Wall Street analysts forecast PFE stock price to rise
16 Analyst Rating
Wall Street analysts forecast PFE stock price to rise
5 Buy
11 Hold
0 Sell
Moderate Buy
Current: 26.480
sliders
Low
24
Averages
28.56
High
35
Current: 26.480
sliders
Low
24
Averages
28.56
High
35
Citi
Geoff Meacham
Neutral
maintain
$26 -> $27
AI Analysis
2026-04-29
Reason
Citi
Geoff Meacham
Price Target
$26 -> $27
AI Analysis
2026-04-29
maintain
Neutral
Reason
Citi analyst Geoff Meacham raised the firm's price target on Pfizer to $27 from $26 and keeps a Neutral rating on the shares.
Morgan Stanley
Equal Weight
maintain
$28
2026-04-28
Reason
Morgan Stanley
Price Target
$28
2026-04-28
maintain
Equal Weight
Reason
Morgan Stanley notes that Pfizer (PFE) announced that it has now reached settlement with all three Vyndamax generic filers, extending the U.S. exclusivity of Vyndamax to June 1, 2031. The firm believes based on its recent conversations that this outcome is at the lower end of investors' expectations of 2031/2032, says the analyst, who adds that this settlement term suggests that the polymorph patent that expires in 2035 is "likely not very strong." The firm has an Equal Weight rating and $28 price target on Pfizer shares. Shares of BridgeBio (BBIO) are down about 2% to $73.07 in morning trading following Pfizer's settlement news.
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