Metsera Shareholders Approve Pfizer's Potential $10 Billion Acquisition
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 13 2025
0mins
Source: Reuters
Pfizer's Acquisition of Metsera: Pfizer's takeover offer for Metsera, valued at up to $10 billion, has been approved by shareholders, allowing Pfizer to re-enter the obesity treatment market after competing with Novo Nordisk.
Market Potential and Drug Pipeline: The obesity drug market is projected to reach $150 billion annually by the end of the decade, and Metsera's lead candidate, MET-097i, shows promise in weight loss, potentially rivaling existing treatments.
Impact on Pfizer's Portfolio: This acquisition helps Pfizer diversify beyond its declining COVID-19 portfolio and addresses upcoming patent expirations, with an expected revenue loss of $17 billion to $18 billion annually from 2026 to 2028.
Support from Major Shareholders: Key shareholders of Metsera, including ARCH Venture Fund and Validae Health, supported the deal, holding approximately 37.6% of the company's outstanding stock as of late September.
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About LLY
Eli Lilly and Company is a medicine company, which discovers, develops, manufactures, and market products in a single business segment called human pharmaceutical products. The Company manufacture and distribute its products through facilities in the United States, including Puerto Rico, and in Europe and Asia. The Company’s products are sold in approximately 90 countries. Its Cardiometabolic Health products Basaglar; Humalog, Humalog Mix 75/25, Humalog U-100, Humalog U-200, Humalog Mix 50/50, insulin lispro, and others; Humulin, Humulin 70/30, and others; Jardiance; Mounjaro; Trulicity; Zepbound, and others. Its oncology products include Cyramza, Erbitux, Tyvyt, Verzenio, Retevmo, Jaypirca, and others. Its immunology products include Ebglyss, Olumiant, Omvoh, and Taltz. Its neuroscience products include Emgality and Kisunla. Its LillyDirect, a direct-to-patient digital health care platform, provides delivery of select Lilly medicines dispensed by third-party pharmacies to patients.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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