Lexeo Therapeutics Partners with J&J to Advance Gene Therapy for Cardiovascular Diseases
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 08 2026
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Source: NASDAQ.COM
- Research Collaboration Initiated: Lexeo Therapeutics has announced a partnership with Johnson & Johnson to focus on localized AAV gene therapy delivery to the heart using Impella heart pump technology, aiming to enhance the efficacy and safety profile for genetically mediated cardiovascular diseases.
- Innovative Technology Application: This collaboration will explore advanced routes of administration, which not only aids in advancing cardiac genetic medicine but also potentially offers more effective treatment options for cardiovascular disease patients, thereby improving their quality of life.
- Positive Market Reaction: Following the announcement, Lexeo's stock price rose by 1.50% to $10.17 in pre-market trading on Nasdaq, reflecting investor optimism regarding the prospects of this collaboration.
- Strategic Implications: CEO Nolan Townsend emphasized that this partnership combines Lexeo's leadership in cardiac genetic medicine with Impella's world-class technology, marking a significant advancement in the next generation of targeted genetic medicines for cardiovascular diseases.
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Analyst Views on JNJ
Wall Street analysts forecast JNJ stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for JNJ is 218.50 USD with a low forecast of 190.00 USD and a high forecast of 240.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
20 Analyst Rating
13 Buy
7 Hold
0 Sell
Moderate Buy
Current: 227.720
Low
190.00
Averages
218.50
High
240.00
Current: 227.720
Low
190.00
Averages
218.50
High
240.00
About JNJ
Johnson & Johnson and its subsidiaries are engaged in the research and development, manufacture, and sale of a range of products in the healthcare field. The Company’s segments include Innovative Medicine and MedTech. The Innovative Medicine segment is focused on various therapeutic areas, including immunology, infectious diseases, neuroscience, oncology, pulmonary hypertension, cardiovascular and metabolism. Its products include REMICADE (infliximab), SIMPONI (golimumab), SIMPONI ARIA (golimumab), STELARA (ustekinumab), TREMFYA (guselkumab), EDURANT (rilpivirine), and INVEGA SUSTENNA/XEPLION (paliperidone palmitate). The MedTech segment includes a portfolio of products used in cardiovascular, orthopedics, surgery, and vision categories. The Cardiovascular portfolio includes electrophysiology products to treat heart rhythm disorders and circulatory restoration products (Shockwave) for the treatment of calcified coronary artery disease (CAD) and peripheral artery disease (PAD).
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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