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LXEO Overview

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0.000(0.000%)Aft-market
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ET
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Intellectia

Loading chart...

High
5.090
Open
4.980
VWAP
4.94
Vol
822.57K
Mkt Cap
383.97M
Low
4.850
Amount
4.07M
EV/EBITDA(TTM)
--
Total Shares
78.52M
EV
194.01M
EV/OCF(TTM)
--
P/S(TTM)
--
Lexeo Therapeutics, Inc. is a clinical-stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimers disease are treated. Using a stepwise development approach, the Company is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of cardiovascular and APOE4-associated Alzheimers disease programs. Its pipeline consists of candidates targeting patient populations. Its most advanced cardiovascular product candidate, LX2006 for the treatment of patients with Friedreichs ataxia (FA), cardiomyopathy, is being evaluated in SUNRISE-FA, an ongoing Phase I/II clinical trial. Its second most advanced cardiovascular product candidate, LX2020 for the treatment of arrhythmogenic cardiomyopathy, caused by mutations in the PKP2 gene (PKP2-ACM), received IND clearance from the United States Food and Drug Administration (FDA).
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Events Timeline

(ET)
2026-06-15
07:30:00
Lexeo Therapeutics Finalizes SUNRISE-FA 2 Trial Protocol
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2026-06-04 (ET)
2026-06-04
14:20:00
FDA Pledges to Prevent Political Interference in Meeting with Rare Disease Nonprofits
select
link
2026-06-02 (ET)
2026-06-02
09:50:00
FDA Issues Draft Guidance for Gene Therapies
select
link
2026-05-12 (ET)
2026-05-12
10:50:00
Trump Plans to Reduce Beef Import Tariffs
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2026-05-11 (ET)
2026-05-11
12:30:00
Trump Approves Firing of FDA Commissioner Makary
select
link
2026-05-11
10:20:00
Trump Plans to Fire FDA Commissioner, Biotech Stocks Affected
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2026-05-08 (ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
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2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
select
link

News

NASDAQ.COM
4.5
06-15NASDAQ.COM
Biotech Stocks Show Significant Pre-Market Activity
  • Significant Pre-Market Gains: Gelteq Limited (GELS) surged 46% to $1.43 in pre-market trading, indicating strong market reaction to its clinical trial progress, which may attract further investor interest in its future performance.
  • Other Gaining Stocks: Park Ha Biological Technology Co., Ltd. (BYAH) rose 20% to $1.77, while Upexi, Inc. (UPXI) increased by 10% to $0.99, reflecting an overall positive sentiment in the biotech sector that could bolster market confidence in related companies.
  • Pre-Market Declines: Elicio Therapeutics, Inc. (ELTX) plummeted 62% to $5.79 in pre-market trading, showcasing market disappointment over its clinical trial results, which may lead investors to reassess its future outlook.
  • Other Declining Stocks: 20/20 Biolabs, Inc. (AIDX) fell 18% to $0.79, highlighting the market's sensitivity to risks associated with biotech companies, potentially impacting overall investment sentiment in the industry.
Newsfilter
8.5
06-15Newsfilter
Lexeo Therapeutics Announces Progress on SUNRISE-FA 2 Trial
  • Trial Design Finalized: Lexeo Therapeutics has finalized the SUNRISE-FA 2 trial protocol and statistical analysis plan, aimed at providing clinical evidence for a Biologics License Application (BLA) submission to the FDA in 2028, marking a significant milestone in the field of gene therapy for cardiovascular diseases.
  • Patient Recruitment Plan: The first patient is expected to be enrolled by the end of June 2026, with the trial including 13 participants aged 16 and older receiving a single high-dose intravenous administration of LX2006, aimed at evaluating its efficacy in Friedreich ataxia cardiomyopathy.
  • Primary Endpoint Metrics: The primary endpoint is the left ventricular mass index (LVMI), assessed via cardiac magnetic resonance imaging (MRI), with topline efficacy data expected at 6 months; the FDA has recommended removing the cardiac frataxin protein expression co-primary endpoint to streamline the trial design.
  • Future Outlook: Lexeo anticipates topline data readout in the second half of 2027 and plans to submit the BLA in the first half of 2028, further advancing the clinical application of gene therapy for cardiovascular diseases and addressing the urgent need for new treatment options for patients.
seekingalpha
9.5
03-30seekingalpha
Lexeo Therapeutics Q4 Earnings Beat Expectations
  • Earnings Performance: Lexeo Therapeutics reported a Q4 GAAP EPS of -$0.27, beating market expectations by $0.04, indicating improvements in financial management that may boost investor confidence.
  • Cash Reserves: As of December 31, 2025, Lexeo's cash, cash equivalents, and marketable securities totaled $246.6 million, which is expected to fund operations into 2028, reflecting the company's financial stability and long-term growth potential.
  • Market Engagement: Lexeo presented at the 2026 Guggenheim Securities Emerging Outlook: Biotech Summit, enhancing its visibility in the biotech sector, which could attract potential investors and partners.
  • Industry Participation: Lexeo also showcased at the 44th Annual J.P. Morgan Healthcare Conference, further solidifying its influence in the industry and potentially paving the way for future financing and collaboration opportunities.
Newsfilter
1.0
02-05Newsfilter
Lexeo Therapeutics Announces Investor Conference Schedule
  • Investor Conference Schedule: Lexeo Therapeutics will participate in two significant investor conferences in February 2026, namely the Guggenheim Emerging Outlook: Biotech Summit and the Oppenheimer 36th Annual Healthcare Life Sciences Conference, showcasing its innovative advancements in cardiovascular disease treatment.
  • Live Webcast and Replay: Both events will be webcast live on the company's investor section of the website, ensuring that investors can access the latest information in real-time, with replays available post-event to enhance engagement and transparency with stakeholders.
  • Company Overview: Lexeo Therapeutics is a New York City-based clinical-stage genetic medicine company focused on reshaping cardiovascular disease treatment through pioneering science, dedicated to developing therapeutic candidates targeting the genetic causes of conditions to meet high unmet medical needs.
  • Therapeutic Candidates: The company is advancing multiple therapeutic candidates, including LX2006 for Friedreich ataxia cardiomyopathy and LX2020 for plakophilin-2 arrhythmogenic cardiomyopathy, demonstrating its potential in addressing diseases with significant unmet needs.
Newsfilter
5.0
01-27Newsfilter
Lexeo Therapeutics Announces Key Senior Leadership Appointments
  • Executive Appointments: Lexeo Therapeutics appoints Dr. Narinder Bhalla as Chief Medical Officer, leveraging over 20 years of experience in cardiovascular medicine and biopharma to drive innovation and development in cardiovascular disease treatments.
  • Strategic Partnership Update: The collaboration with Perceptive Xontogeny Venture Funds and venBio Partners aims to develop therapies for genetic cardiac diseases using a novel non-viral RNA platform, reinforcing Lexeo's leadership in gene therapy.
  • Operational Efficiency Boost: Dr. José Manuel Otero has been appointed Chief Operating Officer, focusing on enhancing Lexeo's operational efficiency and clinical supply capabilities while ensuring a smooth transition of manufacturing platforms under high regulatory standards.
  • R&D Team Expansion: Newly appointed Dr. Hayes Dansky and Dr. Greg Aubert will lead late-stage and early-stage cardiology development, respectively, and their extensive R&D experience is expected to accelerate Lexeo's clinical progress in cardiovascular gene therapies.
Benzinga
6.0
01-13Benzinga
Telsey Raises Five Below Inc Price Target to $240
  • Price Target Increase: Telsey Advisory Group raised the price target for Five Below Inc from $195 to $240, with analyst Joseph Feldman maintaining an Outperform rating, indicating strong confidence in the company's future growth prospects.
  • Rating Maintained: Despite HC Wainwright & Co. cutting Lexeo Therapeutics Inc's price target from $13 to $10, analyst Mitchell S. Kapoor maintained a Buy rating, reflecting optimism about its long-term potential.
  • Price Target Cut: Needham reduced the price target for Apellis Pharmaceuticals Inc from $29 to $28, yet analyst Joseph Stringer upheld a Buy rating, demonstrating ongoing confidence in the company's fundamentals.
  • Rating Downgrade: Daiwa Capital lowered PayPal Holdings Inc's price target from $77 to $61 and downgraded the rating from Outperform to Neutral, indicating a cautious outlook on its future performance.
Wall Street analysts forecast LXEO stock price to rise
7 Analyst Rating
Wall Street analysts forecast LXEO stock price to rise
7 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
13.00
Averages
20.29
High
30.00
Current: 0.000
sliders
Low
13.00
Averages
20.29
High
30.00
JPMorgan
Overweight
to
Overweight
downgrade
$12 -> $9
AI Analysis
2026-06-25
New
Reason
JPMorgan
Price Target
$12 -> $9
AI Analysis
2026-06-25
New
downgrade
Overweight
to
Overweight
Reason
JPMorgan lowered the firm's price target on Lexeo Therapeutics to $9 from $12 and keeps an Overweight rating on the shares. The firm updated the company's model to reflect its recent updates.
Raymond James
initiated
$25
2025-12-17
Reason
Raymond James
Price Target
$25
2025-12-17
initiated
Reason
Raymond James initiated coverage of Lexeo Therapeutics with a Strong Buy rating and $25 price target. Based on strong results from two Phase 1/2 clinical trials and constructive feedback from FDA, Lexeo's lead asset LX2006 for cardiomyopathy associated with Friedreich's Ataxia is "well-positioned for success" in its pivotal trial, the analyst argues. The firm anticipates the stock will move next year on a finalized pivotal protocol with FDA and initial proof of concept data on a second, unmodeled gene therapy asset, LX2020, notes the analyst, who models LX2006 revenue of $14.1M in FY27 and growing to $805.3M in FY32.
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Valuation Metrics

The current forward P/E ratio for Lexeo Therapeutics Inc (LXEO.O) is 0.00, compared to its 5-year average forward P/E of -3.77. For a more detailed relative valuation and DCF analysis to assess Lexeo Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.77
Current PE
0.00
Overvalued PE
-1.92
Undervalued PE
-5.62

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.06
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.38
Undervalued EV/EBITDA
-4.50

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
9.55
Current PS
63.22
Overvalued PS
29.94
Undervalued PS
-10.83

Financials

AI Analysis
Annual
Quarterly

Whales Holding LXEO

A
Avoro Capital Advisors LLC
Holding
LXEO
+27.04%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
LXEO
+24.51%
3M Return
A
Affinity Asset Advisors, LLC
Holding
LXEO
+16.45%
3M Return
F
Frazier Life Sciences Management, LP
Holding
LXEO
+15.79%
3M Return
R
RA Capital Management, L.P.
Holding
LXEO
+15.13%
3M Return
V
Vestal Point Capital, LP
Holding
LXEO
+4.95%
3M Return

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Frequently Asked Questions

What is Lexeo Therapeutics Inc (LXEO) stock price today?

The current price of LXEO is 4.89 USD — it has decreased -0.61

What is Lexeo Therapeutics Inc (LXEO)'s business?

Lexeo Therapeutics, Inc. is a clinical-stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimers disease are treated. Using a stepwise development approach, the Company is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of cardiovascular and APOE4-associated Alzheimers disease programs. Its pipeline consists of candidates targeting patient populations. Its most advanced cardiovascular product candidate, LX2006 for the treatment of patients with Friedreichs ataxia (FA), cardiomyopathy, is being evaluated in SUNRISE-FA, an ongoing Phase I/II clinical trial. Its second most advanced cardiovascular product candidate, LX2020 for the treatment of arrhythmogenic cardiomyopathy, caused by mutations in the PKP2 gene (PKP2-ACM), received IND clearance from the United States Food and Drug Administration (FDA).

What is the price predicton of LXEO Stock?

Wall Street analysts forecast LXEO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LXEO is20.29 USD with a low forecast of 13.00 USD and a high forecast of 30.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Lexeo Therapeutics Inc (LXEO)'s revenue for the last quarter?

Lexeo Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Lexeo Therapeutics Inc (LXEO)'s earnings per share (EPS) for the last quarter?

Lexeo Therapeutics Inc. EPS for the last quarter amounts to -0.25 USD, decreased -74.75

How many employees does Lexeo Therapeutics Inc (LXEO). have?

Lexeo Therapeutics Inc (LXEO) has 59 emplpoyees as of June 27 2026.

What is Lexeo Therapeutics Inc (LXEO) market cap?

Today LXEO has the market capitalization of 383.97M USD.