Notable TWST Put and Call Options Expiring on November 21st
Put Contract Analysis: The $27.50 put contract for TWST has a bid of $1.15, allowing investors to potentially buy shares at a lower cost basis of $26.35, with a 59% chance of expiring worthless, offering a 4.18% return on cash commitment.
Call Contract Strategy: The $32.50 call contract has a bid of $2.05, enabling investors to sell shares at a premium while potentially achieving a 22.52% return if exercised, with a 60% chance of expiring worthless, providing a 7.27% additional return if it does.
Volatility Insights: The implied volatility for the put and call contracts is 84% and 83%, respectively, while the actual trailing twelve-month volatility is calculated at 63%.
YieldBoost Concept: Both put and call strategies offer significant annualized returns, referred to as YieldBoost, with 24.21% for the put and 42.09% for the covered call if the contracts expire worthless.
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Analyst Views on TWST
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- FDA Chaos Impacts Approvals: The biotech sector had a strong performance in 2025, with the XBI index outperforming NVIDIA, yet ongoing chaos at the FDA may lead to longer drug approval cycles, increasing investment risks and affecting industry confidence.
- Executive Warns of Industry Risks: Former FDA oncology head Richard Pasdur warned at the JP Morgan conference that the breach between political appointees and drug reviewers could lead to inconsistent approval standards, creating uncertainty for biotech companies.
- Gene Therapy Approval Delays: Regenxbio's expected approval for a Hunter syndrome drug on February 8 is now unlikely due to a tumor found in a patient during clinical trials, indicating stricter FDA oversight on gene therapies and prompting investor caution.
- Twist Bioscience Shows Recovery: Twist Bioscience reported $104 million in revenue for Q1, despite remaining unprofitable, but reduced cash burn indicates a sustainable growth trend, attracting investor interest amid the biotech downturn.
- Strong Sales Performance: Twist Bioscience reported Q1 sales of $103.7 million, a 17% year-over-year increase, surpassing market expectations of $102.72 million, indicating robust market performance and growth potential.
- Stable Profitability Outlook: The company posted a loss of $0.50 per share, in line with Wall Street expectations, yet management remains focused on achieving profitability with gross margins above 50%, reflecting a healthy financial outlook.
- Raised Sales Guidance: Twist Bioscience increased its fiscal 2026 sales guidance from $425 million-$435 million to $435 million-$440 million, exceeding the consensus of $431.39 million, demonstrating confidence in future growth.
- Analyst Rating Upgrades: Barclays analyst raised the price target from $39 to $50, while Evercore ISI analyst increased the target from $42 to $52, reflecting optimistic market sentiment regarding Twist Bioscience's future performance.

- Earnings Meet Expectations: Twist Bioscience reported a Q1 2026 loss of $0.50 per share, aligning with Wall Street forecasts, while sales reached $103.7 million, a 17% year-over-year increase that surpassed the consensus of $102.72 million, indicating strong market competitiveness and growth potential.
- Customer Base Expansion: The company shipped products to approximately 2,538 customers in Q1, up from about 2,376 a year ago, demonstrating ongoing progress in customer acquisition and market penetration.
- Gene Shipment Growth: Twist shipped approximately 271,000 genes this quarter, significantly up from 205,000 a year prior, with over 50,000 genes manufactured for data characterization, reflecting robust demand in the gene synthesis sector.
- Sales Guidance Raised: The company raised its fiscal 2026 sales guidance from $425 million-$435 million to $435 million-$440 million, with expected Q2 sales between $107 million-$108 million, showcasing confidence in future performance and optimistic market outlook.
- Consistent Growth: Twist Bioscience reported Q1 2026 revenue of $103.7 million, a 17% year-over-year increase, marking the 12th consecutive quarter of revenue growth, demonstrating strong performance in the life sciences tools sector.
- Margin Improvement: The gross margin for Q1 reached 52.0%, up 4 percentage points from the previous year, reflecting the company's success in managing operating expenses, which totaled $86.9 million.
- Optimistic Outlook: The company expects total revenue for fiscal 2026 to be between $435 million and $440 million, with a growth rate of approximately 16%, and reiterated its goal of achieving adjusted EBITDA breakeven in Q4 2026.
- AI-Driven Growth: The company secured over $25 million in orders in the AI-enabled discovery market, projecting a potential addressable market of over $12 billion by 2030, indicating strong market potential and strategic direction.
- Revenue Guidance Raised: Twist Bioscience has raised its FY 2026 total revenue guidance to between $435 million and $440 million, exceeding the analyst estimate of $430.84 million, indicating strong market performance.
- Significant Quarterly Growth: The company expects Q2 revenue to be approximately $107 million to $108 million, marking a year-over-year growth of about 16%, which not only surpasses the estimated $105.08 million but also reflects a growing customer base.
- EBITDA Breakeven Target: Twist anticipates achieving adjusted EBITDA breakeven in Q4 of FY 2026, which will further bolster investor confidence and improve financial health.
- Strong Q1 Performance: For Q1, total revenue reached $103.7 million, a 17% increase that exceeded the expected $100.33 million, with the customer count rising from 2,376 to 2,538, demonstrating robust product demand.
- Financial Performance: Twist Bioscience's Q1 report shows a reduced loss of $30.5 million, or $0.50 per share, compared to last year's loss of $31.6 million, or $0.53 per share, indicating an improvement in financial health.
- Revenue Growth: The company reported Q1 revenue of $103.7 million, up 16.8% from $88.7 million in the same period last year, reflecting strong market demand and sales performance.
- Stock Price Surge: Following the positive earnings report, Twist Bioscience shares rose approximately 7% in Nasdaq trading, currently priced at $44.23, up $3.28 from the previous close of $41.07, showcasing investor optimism about the company's outlook.
- Annual Volatility: Over the past year, Twist Bioscience's stock has fluctuated between $23.30 and $54.74, indicating a mix of high investor interest and uncertainty regarding its future growth potential.









