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TWST Should I Buy

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Intellectia

Should You Buy Twist Bioscience Corp (TWST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
61.410
1 Day change
2.67%
52 Week Range
62.090
Analysis Updated At
2026/04/17
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Twist Bioscience Corp (TWST) is not a strong buy at the moment for a beginner investor with a long-term horizon. While the stock shows some positive technical indicators and moderate analyst optimism, the lack of recent positive news, declining net income, and hedge fund selling trends suggest caution. Holding the stock or waiting for a better entry point is advisable.

Technical Analysis

The technical indicators show a bullish trend with MACD positively expanding, RSI in the neutral zone, and moving averages aligned bullishly (SMA_5 > SMA_20 > SMA_200). The stock is trading near its resistance level (R1: 57.952), which may limit immediate upside potential.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
10

Positive Catalysts

  • Analyst ratings have been consistently raised, with price targets now ranging between $55 and $56, reflecting optimism about the company's growth potential in AI-driven drug discovery and NGS normalization. Gross margin has also improved YoY, indicating operational efficiency.

Neutral/Negative Catalysts

  • Hedge funds are aggressively selling the stock, with a 634.68% increase in selling activity last quarter. Net income and EPS have declined YoY, and there is no recent news or event-driven catalyst to drive the stock higher. Additionally, the stock has a 70% chance to decline slightly (-0.56%) in the next day.

Financial Performance

In Q1 2026, revenue increased by 16.89% YoY to $103.7M, and gross margin improved to 52.05% (+7.79% YoY). However, net income dropped by -3.44% YoY to -$30.5M, and EPS declined by -5.66% YoY to -$0.50, reflecting ongoing profitability challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are optimistic, with multiple firms raising price targets recently. Barclays, Evercore ISI, and Guggenheim have all increased targets to $55-$56, maintaining Overweight, Outperform, and Buy ratings. However, Barclays notes that the sector is 'not without risk,' and sentiment remains at all-time lows.

Wall Street analysts forecast TWST stock price to fall
5 Analyst Rating
Wall Street analysts forecast TWST stock price to fall
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 59.810
sliders
Low
39
Averages
41.25
High
43
Current: 59.810
sliders
Low
39
Averages
41.25
High
43
Barclays
Luke Sergott
Overweight
maintain
$50 -> $55
AI Analysis
2026-04-14
Reason
Barclays
Luke Sergott
Price Target
$50 -> $55
AI Analysis
2026-04-14
maintain
Overweight
Reason
Barclays analyst Luke Sergott raised the firm's price target on Twist Bioscience to $55 from $50 and keeps an Overweight rating on the shares. The firm adjusted targets in the life science and diagnostic tools group as part of a Q1 preview. Barclays likes the setup for the sector but says it is "not without risk." Sentiment is at all-time lows and Barclays still believes in the "last-cut thesis (for the most part)," the analyst tells investors in a research note.
Evercore ISI
Vijay Kumar
Outperform
maintain
$52 -> $56
2026-04-06
Reason
Evercore ISI
Vijay Kumar
Price Target
$52 -> $56
2026-04-06
maintain
Outperform
Reason
Evercore ISI analyst Vijay Kumar raised the firm's price target on Twist Bioscience to $56 from $52 and keeps an Outperform rating on the shares as part of the firm's medical technology and life science tools Q1 preview.
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