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TWST Should I Buy

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Intellectia

Should You Buy Twist Bioscience Corp (TWST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
45.400
1 Day change
-6.07%
52 Week Range
57.880
Analysis Updated At
2026/03/06
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Twist Bioscience Corp (TWST) is not a strong buy at the moment for a beginner, long-term investor. While the company shows potential for growth in the AI-driven drug discovery market and has received positive analyst ratings with raised price targets, the current technical indicators, financial performance, and trading sentiment do not support an immediate buy decision. The stock is experiencing a downward trend, and hedge funds are significantly selling, which could indicate short-term weakness. A 'hold' position is recommended until more favorable entry points or stronger signals emerge.

Technical Analysis

The technical indicators suggest a bearish trend. The MACD is negatively expanding below 0 (-0.711), RSI is neutral at 40.797, and moving averages are converging, indicating indecision. The stock is trading near its pivot level of 47.128, with support at 44.137 and resistance at 50.119. The stock has a 40% chance of declining further in the short term.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Options data shows a low put-call ratio, indicating a lack of bearish sentiment in the options market. However, the low call volume (56) and implied volatility (86.56) suggest limited activity and potential uncertainty.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
6

Positive Catalysts

  • Positive analyst ratings and raised price targets driven by AI-driven drug discovery and NGS normalization. Revenue growth of 16.89% YoY in Q1 2026 and improved gross margin (52.05, up 7.79% YoY) indicate operational improvements.

Neutral/Negative Catalysts

  • Significant hedge fund selling (634.68% increase in selling over the last quarter). Net income dropped by -3.44% YoY, and EPS declined by -5.66% YoY. No recent news or congress trading data to support a bullish sentiment. The stock is currently down -4.09% in regular market trading and -5.47% in pre-market trading.

Financial Performance

In Q1 2026, revenue increased by 16.89% YoY to $103.7M, and gross margin improved to 52.05 (up 7.79% YoY). However, net income dropped to -$30.5M (-3.44% YoY), and EPS declined to -0.5 (-5.66% YoY), indicating ongoing profitability challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are optimistic, with multiple firms raising price targets to $50-$52 and maintaining Outperform or Buy ratings. The company is seen as well-positioned for growth in AI-driven drug discovery and diagnostics tools, with solid momentum into FY26.

Wall Street analysts forecast TWST stock price to fall
5 Analyst Rating
Wall Street analysts forecast TWST stock price to fall
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 48.330
sliders
Low
39
Averages
41.25
High
43
Current: 48.330
sliders
Low
39
Averages
41.25
High
43
Evercore ISI
Outperform
maintain
$42 -> $52
AI Analysis
2026-02-03
Reason
Evercore ISI
Price Target
$42 -> $52
AI Analysis
2026-02-03
maintain
Outperform
Reason
Evercore ISI raised the firm's price target on Twist Bioscience to $52 from $42 and keeps an Outperform rating on the shares. Driven by NGS normalization and AI-driven drug discovery, Twist Bioscience is "set for solid growth into FY26," the analyst tells investors.
Baird
Outperform
upgrade
$33 -> $50
2026-02-03
Reason
Baird
Price Target
$33 -> $50
2026-02-03
upgrade
Outperform
Reason
Baird raised the firm's price target on Twist Bioscience to $50 from $33 and keeps an Outperform rating on the shares. The firm uppdated its model following Q4 results where the company raised its 2026 revenue guidance on broad based momentum.
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